Best TWAS P=3.57e-16 · Best GWAS P=5.05e-25 conditioned to 1.51e-10
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | KRT8P33 | 0.10 | 0.04 | lasso | 6 | 0.05 | 9.1e-04 | -4.2 | 5.8 | 5.2e-09 | -0.62 | 0.04 | 0.85 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CSNK1G3 | 0.04 | 0.02 | enet | 8 | 0.02 | 1.2e-04 | 4.3 | 6.4 | 2.0e-10 | -0.56 | 0.02 | 0.14 | FALSE |
| 3 | The Cancer Genome Atlas | Colon Adenocarcinoma | CEP120 | 0.06 | 0.02 | blup | 70 | 0.04 | 3.6e-03 | 6.1 | 7.9 | 2.7e-15 | -0.64 | 0.13 | 0.15 | FALSE |
| 4 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | CEP120 | 0.03 | 0.02 | enet | 5 | 0.04 | 7.3e-05 | -4.2 | 7.3 | 2.6e-13 | -0.66 | 0.03 | 0.83 | FALSE |
| 5 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CEP120 | 0.10 | 0.14 | blup | 70 | 0.14 | 2.6e-14 | -9.5 | 8.2 | 3.6e-16 | -0.83 | 0.17 | 0.83 | TRUE |