Best TWAS P=1.73e-13 · Best GWAS P=1.09e-16 conditioned to 1.29e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Gastroesophageal Junction | CDKN2C | 0.14 | 0.11 | enet | 17 | 0.12 | 3.0e-05 | 6.2 | -5.6 | 2.2e-08 | 0.03 | 0.10 | 0.66 | TRUE |
| 2 | METSIM | Adipose | AGBL4 | 0.02 | 0.02 | lasso | 5 | 0.02 | 1.3e-03 | 7.2 | -7.4 | 1.7e-13 | -0.86 | 0.15 | 0.83 | TRUE |
| 3 | YFS | Blood | TAL1 | 0.03 | 0.02 | bslmm | 402 | 0.02 | 2.6e-06 | 5.9 | -6.0 | 2.0e-09 | 0.02 | 0.01 | 0.99 | TRUE |