[Hub]/) : Traits : Weight :

chr1:40,748,755-43,576,321

Best TWAS P=1.24e-16 · Best GWAS P=2.86e-16 conditioned to 0.00963

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta CTPS1 0.10 0.00 enet 8 0.00 4.6e-01 6.23 7.1 1.6e-12 0.74 0.05 0.59 FALSE
2 GTEx Artery Coronary CTPS1 0.25 -0.01 enet 23 0.00 3.0e-01 -0.81 5.8 5.7e-09 0.39 0.07 0.13 FALSE
3 GTEx Brain Cerebellum HIVEP3 0.23 0.16 lasso 6 0.19 2.8e-06 4.51 5.8 8.5e-09 0.06 0.57 0.03 TRUE
4 GTEx Cells EBV-transformed lymphocytes CTPS1 0.26 0.11 lasso 6 0.08 1.6e-03 7.02 6.7 2.6e-11 0.69 0.19 0.37 FALSE
5 GTEx Lung CTPS1 0.06 0.04 lasso 3 0.04 2.4e-04 7.41 7.3 3.1e-13 0.77 0.21 0.64 FALSE
6 GTEx Nerve Tibial SCMH1 0.16 0.03 enet 24 0.07 1.6e-05 7.55 -6.0 2.6e-09 -0.69 0.03 0.96 FALSE
7 GTEx Testis SLFNL1 0.30 0.17 lasso 14 0.28 5.3e-13 8.18 5.4 5.3e-08 0.86 0.01 0.99 FALSE
8 ROSMAP Brain Pre-frontal Cortex RIMKLA 0.06 0.06 bslmm 341 0.05 1.3e-07 -4.30 6.1 1.2e-09 0.03 0.97 0.01 TRUE
9 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma RIMKLA 0.03 0.02 blup 53 0.01 2.8e-02 4.86 5.3 1.1e-07 0.06 0.00 0.86 FALSE
10 The Cancer Genome Atlas Prostate Adenocarcinoma SCMH1 0.03 0.03 lasso 2 0.02 6.2e-03 8.08 -8.1 6.5e-16 -0.98 0.01 0.96 FALSE
11 The Cancer Genome Atlas Testicular Germ Cell Tumors SCMH1 0.35 0.14 blup 96 0.14 1.5e-05 -3.64 5.2 2.6e-07 0.47 0.17 0.29 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma SCMH1 0.07 0.08 blup 97 0.07 2.5e-07 7.62 -8.3 1.2e-16 -0.73 0.17 0.83 TRUE