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chr1:40,748,755-43,576,321

Best TWAS P=1.24e-16 · Best GWAS P=2.86e-16 conditioned to 0.00963

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
12	The Cancer Genome Atlas	Thyroid Carcinoma	SCMH1	0.07	0.08	blup	97	0.07	2.5e-07	7.62	-8.3	1.2e-16	-0.73	0.17	0.83	TRUE
8	ROSMAP	Brain Pre-frontal Cortex	RIMKLA	0.06	0.06	bslmm	341	0.05	1.3e-07	-4.30	6.1	1.2e-09	0.03	0.97	0.01	TRUE
3	GTEx	Brain Cerebellum	HIVEP3	0.23	0.16	lasso	6	0.19	2.8e-06	4.51	5.8	8.5e-09	0.06	0.57	0.03	TRUE
10	The Cancer Genome Atlas	Prostate Adenocarcinoma	SCMH1	0.03	0.03	lasso	2	0.02	6.2e-03	8.08	-8.1	6.5e-16	-0.98	0.01	0.96	FALSE
5	GTEx	Lung	CTPS1	0.06	0.04	lasso	3	0.04	2.4e-04	7.41	7.3	3.1e-13	0.77	0.21	0.64	FALSE
1	GTEx	Artery Aorta	CTPS1	0.10	0.00	enet	8	0.00	4.6e-01	6.23	7.1	1.6e-12	0.74	0.05	0.59	FALSE
4	GTEx	Cells EBV-transformed lymphocytes	CTPS1	0.26	0.11	lasso	6	0.08	1.6e-03	7.02	6.7	2.6e-11	0.69	0.19	0.37	FALSE
6	GTEx	Nerve Tibial	SCMH1	0.16	0.03	enet	24	0.07	1.6e-05	7.55	-6.0	2.6e-09	-0.69	0.03	0.96	FALSE
2	GTEx	Artery Coronary	CTPS1	0.25	-0.01	enet	23	0.00	3.0e-01	-0.81	5.8	5.7e-09	0.39	0.07	0.13	FALSE
7	GTEx	Testis	SLFNL1	0.30	0.17	lasso	14	0.28	5.3e-13	8.18	5.4	5.3e-08	0.86	0.01	0.99	FALSE
9	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	RIMKLA	0.03	0.02	blup	53	0.01	2.8e-02	4.86	5.3	1.1e-07	0.06	0.00	0.86	FALSE
11	The Cancer Genome Atlas	Testicular Germ Cell Tumors	SCMH1	0.35	0.14	blup	96	0.14	1.5e-05	-3.64	5.2	2.6e-07	0.47	0.17	0.29	FALSE