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chr8:8,165,004-10,985,432
Best TWAS P=7.75e-09 · Best GWAS P=3.5e-10 conditioned to 0.00259
8M
8.5M
9M
9.5M
10M
10.5M
11M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
GTEx
Esophagus Gastroesophageal Junction
MSRA
0.11
-0.01
enet
30
-0.01
8.0e-01
4.9
-5.8
7.7e-09
0.51
0.17
0.15
TRUE
4
GTEx
Small Intestine Terminal Ileum
RP11-375N15.2
0.36
0.20
lasso
5
0.14
4.9e-04
5.6
5.4
8.6e-08
-0.37
0.02
0.95
TRUE
5
NTR
Blood
MSRA
0.02
0.01
blup
833
0.01
2.3e-05
3.3
-5.7
1.0e-08
0.57
0.33
0.66
FALSE
1
GTEx
Adipose Subcutaneous
ERI1
0.05
0.00
enet
10
0.00
5.5e-01
5.7
-5.3
9.5e-08
0.49
0.02
0.95
FALSE
2
GTEx
Colon Transverse
RP11-375N15.2
0.09
0.10
lasso
5
0.07
2.4e-04
4.6
5.3
1.3e-07
-0.45
0.04
0.95
FALSE