Best TWAS P=7.75e-09 · Best GWAS P=3.5e-10 conditioned to 0.00259
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | ERI1 | 0.05 | 0.00 | enet | 10 | 0.00 | 5.5e-01 | 5.7 | -5.3 | 9.5e-08 | 0.49 | 0.02 | 0.95 | FALSE |
| 2 | GTEx | Colon Transverse | RP11-375N15.2 | 0.09 | 0.10 | lasso | 5 | 0.07 | 2.4e-04 | 4.6 | 5.3 | 1.3e-07 | -0.45 | 0.04 | 0.95 | FALSE |
| 3 | GTEx | Esophagus Gastroesophageal Junction | MSRA | 0.11 | -0.01 | enet | 30 | -0.01 | 8.0e-01 | 4.9 | -5.8 | 7.7e-09 | 0.51 | 0.17 | 0.15 | TRUE |
| 4 | GTEx | Small Intestine Terminal Ileum | RP11-375N15.2 | 0.36 | 0.20 | lasso | 5 | 0.14 | 4.9e-04 | 5.6 | 5.4 | 8.6e-08 | -0.37 | 0.02 | 0.95 | TRUE |
| 5 | NTR | Blood | MSRA | 0.02 | 0.01 | blup | 833 | 0.01 | 2.3e-05 | 3.3 | -5.7 | 1.0e-08 | 0.57 | 0.33 | 0.66 | FALSE |