[Hub]/) : Traits : Overall health rating : ← →

chr9:126,927,285-129,422,783

Best TWAS P=1.42e-12 · Best GWAS P=1.2e-12 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
17	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PBX3	0.04	0.07	lasso	3	0.06	6.7e-07	-7.1	-7.1	1.4e-12	1.00	0.00	1.00	TRUE
16	GTEx	Thyroid	PBX3	0.07	0.00	lasso	6	0.01	4.7e-02	-6.8	-6.3	2.3e-10	0.62	0.04	0.91	TRUE
14	GTEx	Testis	PBX3	0.19	0.22	lasso	3	0.20	4.7e-09	-6.2	-6.1	8.6e-10	0.91	0.09	0.91	TRUE
10	GTEx	Heart Atrial Appendage	PBX3	0.10	0.08	lasso	6	0.04	9.0e-03	-5.4	-5.8	6.1e-09	0.85	0.05	0.84	TRUE
9	GTEx	Esophagus Muscularis	PBX3	0.12	0.08	lasso	7	0.09	4.2e-06	-5.4	-5.8	8.9e-09	0.88	0.06	0.94	TRUE
20	The Cancer Genome Atlas	Brain Lower Grade Glioma	WDR38	0.03	0.01	enet	6	0.02	4.9e-03	4.0	5.5	4.9e-08	-0.17	0.02	0.70	TRUE
18	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	GOLGA1	0.07	0.01	blup	47	0.02	1.5e-02	-5.2	-5.4	6.3e-08	0.21	0.02	0.79	TRUE
7	GTEx	Esophagus Gastroesophageal Junction	PBX3	0.21	0.19	lasso	5	0.14	1.0e-05	-4.8	-5.3	1.1e-07	0.84	0.15	0.82	TRUE
21	The Cancer Genome Atlas	Prostate Adenocarcinoma	PBX3	0.03	0.03	blup	65	0.04	5.4e-05	-6.1	-6.5	6.9e-11	0.90	0.03	0.96	FALSE
11	GTEx	Heart Left Ventricle	PBX3	0.21	0.22	lasso	4	0.21	3.3e-11	-6.1	-6.2	7.7e-10	0.91	0.14	0.86	FALSE
12	GTEx	Skin Not Sun Exposed Suprapubic	PBX3	0.12	0.13	lasso	2	0.13	1.8e-07	-5.4	-6.1	9.5e-10	0.91	0.05	0.95	FALSE
4	GTEx	Artery Tibial	PBX3	0.11	0.07	lasso	2	0.06	8.1e-06	-5.4	-5.8	6.7e-09	0.87	0.15	0.77	FALSE
13	GTEx	Testis	PPP6C	0.10	0.03	enet	13	0.01	1.1e-01	-5.0	5.7	1.1e-08	-0.26	0.05	0.69	FALSE
2	GTEx	Adipose Subcutaneous	PBX3	0.17	0.08	lasso	6	0.10	2.4e-08	-5.9	-5.5	4.5e-08	0.87	0.29	0.70	FALSE
1	GTEx	Adipose Subcutaneous	GOLGA1	0.04	0.05	lasso	1	0.05	8.6e-05	-5.4	-5.4	6.5e-08	0.24	0.02	0.97	FALSE
15	GTEx	Thyroid	ARPC5L	0.18	0.12	enet	17	0.16	1.5e-12	-5.4	-5.4	7.3e-08	0.29	0.02	0.98	FALSE
8	GTEx	Esophagus Muscularis	GOLGA1	0.12	0.05	lasso	9	0.06	2.4e-04	-5.0	-5.3	1.3e-07	0.22	0.05	0.94	FALSE
3	GTEx	Adipose Subcutaneous	SCAI	0.07	0.05	lasso	4	0.02	7.4e-03	-5.4	5.3	1.4e-07	-0.30	0.04	0.96	FALSE
5	GTEx	Brain Cerebellum	ARPC5L	0.31	0.37	enet	7	0.27	1.5e-08	-5.3	-5.2	2.1e-07	0.24	0.06	0.94	FALSE
6	GTEx	Colon Sigmoid	PBX3	0.23	0.22	lasso	3	0.16	1.9e-06	-5.4	-5.2	2.2e-07	0.81	0.25	0.74	FALSE
19	The Cancer Genome Atlas	Brain Lower Grade Glioma	SCAI	0.02	0.02	blup	94	0.01	2.1e-02	-5.0	5.2	2.5e-07	-0.29	0.02	0.88	FALSE