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chr17:65,289,798-66,844,411

Best TWAS P=7.62e-09 · Best GWAS P=7.65e-09 conditioned to 0.0511

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	LINC00674	0.12	0.13	enet	6	0.14	9.9e-12	5.3	5.8	7.6e-09	0.79	0.17	0.83	TRUE
12	The Cancer Genome Atlas	Thyroid Carcinoma	C17orf58	0.02	0.02	lasso	2	0.01	1.8e-02	5.7	5.7	1.1e-08	0.99	0.00	0.76	FALSE
3	GTEx	Brain Cortex	C17orf58	0.34	0.09	lasso	6	0.13	2.4e-04	5.7	5.7	1.3e-08	0.95	0.03	0.95	FALSE
2	GTEx	Adipose Subcutaneous	SH3GL1P3	0.08	0.06	lasso	5	0.04	2.5e-04	5.3	5.7	1.4e-08	0.80	0.04	0.93	FALSE
6	GTEx	Cells Transformed fibroblasts	SH3GL1P3	0.26	0.31	lasso	7	0.31	1.5e-23	5.3	5.6	1.8e-08	0.90	0.19	0.81	FALSE
8	GTEx	Esophagus Muscularis	LINC00674	0.11	0.04	lasso	6	0.07	7.9e-05	4.0	5.4	7.8e-08	0.77	0.16	0.82	FALSE
5	GTEx	Cells Transformed fibroblasts	LRRC37A16P	0.50	0.46	lasso	8	0.47	1.1e-38	5.3	5.4	7.9e-08	0.84	0.20	0.80	FALSE
10	GTEx	Nerve Tibial	LRRC37A16P	0.09	0.08	lasso	4	0.06	2.7e-05	5.3	5.4	8.4e-08	0.84	0.08	0.82	FALSE
7	GTEx	Colon Sigmoid	LINC00674	0.42	0.09	lasso	8	0.12	5.5e-05	4.8	5.3	9.0e-08	0.81	0.11	0.74	FALSE
4	GTEx	Cells Transformed fibroblasts	LINC00674	0.30	0.31	enet	10	0.32	1.5e-24	5.3	5.3	9.2e-08	0.86	0.20	0.80	FALSE
11	GTEx	Spleen	C17orf58	0.30	-0.01	lasso	8	-0.01	4.6e-01	4.3	5.2	2.2e-07	0.81	0.03	0.35	FALSE
9	GTEx	Heart Atrial Appendage	LINC00674	0.14	0.08	lasso	17	0.09	1.1e-04	4.0	5.1	2.7e-07	0.73	0.07	0.84	FALSE