[Hub]/) : Traits : Hearing difficulty/problems with background noise :

chr5:72,232,417-73,934,274

Best TWAS P=7.94e-10 · Best GWAS P=5.28e-13 conditioned to 0.00117

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Nerve Tibial ARHGEF28 0.15 0.03 lasso 5 0.06 6.7e-05 -5.6 -6.1 7.9e-10 -0.29 0.61 0.08 TRUE
2 The Cancer Genome Atlas Liver Hepatocellular Carcinoma RGNEF 0.16 0.04 lasso 4 0.06 1.0e-03 -4.9 5.4 5.5e-08 0.23 0.28 0.03 FALSE
3 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma RGNEF 0.15 0.09 lasso 7 0.07 7.8e-04 -5.8 5.9 2.9e-09 0.33 0.24 0.07 FALSE
4 The Cancer Genome Atlas Prostate Adenocarcinoma RGNEF 0.20 0.14 lasso 4 0.20 1.3e-20 -6.1 -6.0 2.3e-09 -0.23 0.94 0.06 TRUE
5 The Cancer Genome Atlas Skin Cutaneous Melanoma RGNEF 0.18 0.00 blup 254 0.08 3.7e-03 3.9 5.1 3.0e-07 0.63 0.07 0.31 TRUE