[Hub]/) : Traits : Body fat percentage :

chr15:40,828,922-42,468,786

Best TWAS P=6.44e-09 · Best GWAS P=5.99e-09 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous OIP5-AS1 0.21 0.23 lasso 5 0.26 3.7e-21 4.9 5.3 1.1e-07 0.73 0.18 0.81 FALSE
2 GTEx Adrenal Gland OIP5-AS1 0.17 0.16 lasso 3 0.16 2.6e-06 5.2 5.3 1.3e-07 0.77 0.11 0.86 FALSE
3 GTEx Artery Coronary OIP5-AS1 0.12 0.13 lasso 2 0.14 2.3e-05 5.3 5.3 9.2e-08 0.74 0.12 0.82 FALSE
4 GTEx Artery Tibial OIP5-AS1 0.16 0.23 lasso 4 0.24 3.6e-19 4.8 5.2 2.0e-07 0.75 0.29 0.71 FALSE
5 GTEx Brain Caudate basal ganglia NUSAP1 0.31 0.38 lasso 9 0.40 1.1e-12 5.2 5.5 4.2e-08 0.78 0.08 0.92 FALSE
6 GTEx Brain Cerebellar Hemisphere NDUFAF1 0.20 0.23 lasso 6 0.22 2.2e-06 5.3 -5.5 4.2e-08 -0.77 0.08 0.90 FALSE
7 GTEx Brain Cerebellum NUSAP1 0.22 0.23 enet 18 0.22 3.7e-07 5.2 5.2 1.7e-07 0.78 0.09 0.90 FALSE
8 GTEx Brain Cerebellum NDUFAF1 0.24 0.26 lasso 8 0.20 1.1e-06 5.4 -5.3 1.1e-07 -0.77 0.06 0.94 FALSE
9 GTEx Brain Cortex NDUFAF1 0.40 0.37 enet 22 0.36 7.0e-11 5.0 -5.4 7.1e-08 -0.69 0.15 0.85 FALSE
10 GTEx Brain Frontal Cortex BA9 NDUFAF1 0.55 0.37 lasso 8 0.40 1.6e-11 5.4 -5.5 5.1e-08 -0.74 0.08 0.92 FALSE
11 GTEx Brain Hypothalamus NUSAP1 0.26 0.36 lasso 4 0.27 5.6e-07 5.2 5.5 3.4e-08 0.66 0.10 0.88 FALSE
12 GTEx Brain Nucleus accumbens basal ganglia NUSAP1 0.36 0.32 lasso 6 0.26 1.5e-07 5.4 5.3 1.4e-07 0.76 0.08 0.91 FALSE
13 GTEx Brain Nucleus accumbens basal ganglia NDUFAF1 0.12 0.11 lasso 6 0.10 9.7e-04 5.3 -5.5 4.7e-08 -0.73 0.08 0.78 FALSE
14 GTEx Brain Putamen basal ganglia NUSAP1 0.38 0.30 lasso 20 0.34 9.1e-09 5.2 5.3 9.7e-08 0.75 0.11 0.89 FALSE
15 GTEx Cells EBV-transformed lymphocytes OIP5-AS1 0.21 0.12 lasso 7 0.10 3.2e-04 5.4 5.4 5.2e-08 0.83 0.07 0.77 FALSE
16 GTEx Cells Transformed fibroblasts CHP1 0.13 0.11 lasso 6 0.11 2.1e-08 5.5 -5.7 1.2e-08 -0.94 0.04 0.96 FALSE
17 GTEx Cells Transformed fibroblasts OIP5-AS1 0.28 0.32 lasso 2 0.32 3.5e-24 5.4 5.4 7.9e-08 0.73 0.07 0.93 FALSE
18 GTEx Colon Sigmoid OIP5-AS1 0.21 0.27 lasso 3 0.25 3.3e-09 5.4 5.4 5.2e-08 0.76 0.12 0.88 FALSE
19 GTEx Colon Transverse OIP5-AS1 0.13 0.14 lasso 5 0.15 1.8e-07 5.4 5.3 9.7e-08 0.75 0.12 0.88 FALSE
20 GTEx Esophagus Gastroesophageal Junction OIP5-AS1 0.18 0.10 lasso 7 0.11 8.9e-05 5.4 5.5 4.9e-08 0.85 0.09 0.88 FALSE
21 GTEx Esophagus Mucosa OIP5-AS1 0.20 0.22 lasso 6 0.20 1.7e-13 5.2 5.3 1.3e-07 0.76 0.12 0.88 FALSE
22 GTEx Esophagus Muscularis NDUFAF1 0.24 0.23 lasso 5 0.28 2.8e-17 5.3 -5.1 2.9e-07 -0.69 0.12 0.88 FALSE
23 GTEx Esophagus Muscularis OIP5-AS1 0.24 0.24 enet 19 0.28 4.6e-17 5.4 5.2 1.5e-07 0.73 0.15 0.85 FALSE
24 GTEx Heart Atrial Appendage NDUFAF1 0.36 0.28 enet 24 0.34 9.5e-16 5.4 -5.6 2.4e-08 -0.73 0.06 0.94 FALSE
25 GTEx Heart Atrial Appendage RTF1 0.14 0.07 lasso 4 0.08 2.4e-04 5.7 -5.8 6.4e-09 -0.98 0.02 0.97 TRUE
26 GTEx Heart Left Ventricle NDUFAF1 0.49 0.62 lasso 8 0.62 2.0e-41 5.4 -5.5 3.1e-08 -0.75 0.05 0.95 FALSE
27 GTEx Muscle Skeletal NDUFAF1 0.44 0.56 enet 31 0.60 3.0e-73 5.3 -5.3 1.5e-07 -0.78 0.06 0.94 FALSE
28 GTEx Nerve Tibial OIP5 0.07 0.08 lasso 2 0.05 1.6e-04 5.0 5.2 2.0e-07 0.91 0.02 0.98 FALSE
29 GTEx Nerve Tibial NUSAP1 0.15 0.09 enet 10 0.15 9.8e-11 5.2 5.3 8.6e-08 0.84 0.10 0.90 FALSE
30 GTEx Nerve Tibial NDUFAF1 0.36 0.43 lasso 6 0.43 8.0e-33 5.2 5.4 8.3e-08 0.74 0.07 0.93 FALSE
31 GTEx Nerve Tibial OIP5-AS1 0.20 0.22 enet 21 0.26 1.3e-18 5.3 5.3 9.6e-08 0.73 0.12 0.88 FALSE
32 GTEx Pancreas NDUFAF1 0.41 0.39 enet 20 0.42 2.7e-19 5.3 5.5 2.8e-08 0.75 0.06 0.94 FALSE
33 GTEx Prostate NDUFAF1 0.30 0.12 lasso 2 0.14 2.7e-04 5.5 5.7 1.3e-08 0.88 0.04 0.85 FALSE
34 GTEx Skin Not Sun Exposed Suprapubic OIP5-AS1 0.17 0.19 enet 17 0.22 4.3e-12 5.0 5.3 1.1e-07 0.80 0.13 0.87 FALSE
35 GTEx Skin Sun Exposed Lower leg OIP5-AS1 0.13 0.17 lasso 3 0.23 5.0e-19 4.9 5.4 8.5e-08 0.80 0.28 0.72 FALSE
36 GTEx Thyroid OIP5 0.06 0.03 lasso 5 0.02 1.1e-02 5.2 5.6 2.2e-08 0.76 0.10 0.80 FALSE
37 GTEx Thyroid NDUFAF1 0.25 0.21 lasso 6 0.22 9.3e-17 5.3 5.5 3.2e-08 0.81 0.07 0.93 FALSE
38 GTEx Whole Blood NDUFAF1 0.25 0.07 lasso 6 0.12 6.4e-11 5.0 5.2 2.5e-07 0.81 0.07 0.93 FALSE
39 METSIM Adipose NUSAP1 0.03 0.03 lasso 6 0.02 4.2e-04 5.1 5.2 2.7e-07 0.77 0.13 0.81 FALSE
40 The Cancer Genome Atlas Brain Lower Grade Glioma NDUFAF1 0.03 0.04 lasso 3 0.04 3.2e-05 5.3 -5.3 9.0e-08 -0.77 0.02 0.98 FALSE
41 The Cancer Genome Atlas Lung Adenocarcinoma NDUFAF1 0.14 0.17 lasso 5 0.18 9.6e-21 5.3 5.2 1.7e-07 0.74 0.01 0.99 FALSE
42 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma LOC729082 0.15 0.05 blup 44 0.10 8.6e-05 5.4 -5.6 2.4e-08 -0.72 0.04 0.83 FALSE
43 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma NDUFAF1 0.18 0.21 blup 28 0.22 5.4e-09 5.3 5.2 1.5e-07 0.76 0.01 0.99 FALSE
44 The Cancer Genome Atlas Prostate Adenocarcinoma NDUFAF1 0.13 0.16 enet 8 0.17 2.2e-17 5.3 5.2 2.2e-07 0.74 0.01 0.99 FALSE
45 The Cancer Genome Atlas Thyroid Carcinoma NDUFAF1 0.32 0.38 enet 11 0.39 1.2e-39 5.3 5.3 1.3e-07 0.76 0.01 0.99 FALSE