Best TWAS P=3.62e-10 · Best GWAS P=4.35e-14 conditioned to 0.00167
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | NEO1 | 0.20 | 0.13 | lasso | 7 | 0.17 | 1.1e-10 | -5.9 | 5.6 | 1.9e-08 | -0.45 | 0.95 | 0.05 | FALSE |
| 2 | GTEx | Heart Atrial Appendage | RP11-1006G14.4 | 0.12 | 0.06 | lasso | 11 | 0.05 | 2.3e-03 | -5.8 | -5.4 | 7.6e-08 | 0.37 | 0.12 | 0.10 | FALSE |
| 3 | GTEx | Nerve Tibial | NEO1 | 0.07 | 0.09 | lasso | 2 | 0.09 | 3.9e-07 | -5.9 | -5.9 | 2.8e-09 | 0.45 | 0.83 | 0.13 | TRUE |
| 4 | GTEx | Pituitary | BBS4 | 0.27 | 0.02 | enet | 21 | 0.05 | 2.1e-02 | -5.4 | -6.3 | 3.6e-10 | 0.69 | 0.05 | 0.50 | TRUE |
| 5 | GTEx | Testis | ADPGK-AS1 | 0.17 | 0.05 | lasso | 4 | 0.03 | 1.3e-02 | -4.3 | 6.2 | 4.9e-10 | -0.72 | 0.02 | 0.90 | FALSE |
| 6 | NTR | Blood | NEO1 | 0.04 | 0.01 | lasso | 4 | 0.02 | 4.1e-06 | 5.2 | -5.5 | 4.6e-08 | 0.25 | 0.93 | 0.01 | FALSE |