[Hub]/) : Traits : Body fat percentage :

chr19:32,209,988-34,959,979

Best TWAS P=2.32e-21 · Best GWAS P=3.59e-19 conditioned to 0.135

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DPY19L3 0.07 0.05 lasso 2 0.06 8.7e-08 -5.4 -5.2 2.3e-07 -0.01 0.00 0.99 TRUE
2 CommonMind Brain Pre-frontal Cortex PEPD 0.32 0.27 enet 22 0.38 1.2e-49 1.7 5.6 2.6e-08 0.48 1.00 0.00 FALSE
3 GTEx Adipose Subcutaneous PEPD 0.30 0.25 lasso 6 0.26 2.5e-21 5.7 5.2 1.6e-07 0.73 1.00 0.00 FALSE
4 GTEx Breast Mammary Tissue PEPD 0.16 0.06 lasso 4 0.04 3.5e-03 5.7 6.4 1.9e-10 0.78 0.35 0.61 FALSE
5 GTEx Colon Transverse PEPD 0.14 0.16 lasso 2 0.13 1.2e-06 5.7 5.6 1.9e-08 0.71 0.61 0.25 FALSE
6 GTEx Esophagus Mucosa PEPD 0.37 0.32 enet 20 0.39 9.5e-28 5.7 7.9 3.4e-15 0.87 0.01 0.99 FALSE
7 METSIM Adipose CHST8 0.22 0.17 lasso 4 0.17 3.7e-25 5.7 5.9 3.0e-09 0.73 1.00 0.00 FALSE
8 METSIM Adipose PEPD 0.19 0.18 lasso 5 0.17 2.3e-24 5.7 5.8 8.2e-09 0.73 1.00 0.00 FALSE
9 The Cancer Genome Atlas Bladder Urothelial Carcinoma PEPD 0.06 0.01 blup 114 0.04 2.6e-04 8.9 7.7 1.6e-14 0.84 0.01 0.97 FALSE
10 The Cancer Genome Atlas Colon Adenocarcinoma PEPD 0.13 0.06 blup 113 0.10 1.2e-06 5.1 9.5 2.3e-21 0.86 0.01 0.99 TRUE
11 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PEPD 0.04 0.05 blup 113 0.03 1.9e-04 -6.3 5.9 4.1e-09 0.53 0.53 0.20 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma PEPD 0.05 0.03 blup 113 0.05 7.1e-07 6.5 5.4 8.1e-08 0.69 0.06 0.94 FALSE
13 The Cancer Genome Atlas Liver Hepatocellular Carcinoma PEPD 0.16 0.07 lasso 3 0.05 3.1e-03 8.9 8.6 6.5e-18 0.95 0.01 0.97 FALSE
14 The Cancer Genome Atlas Prostate Adenocarcinoma PEPD 0.08 0.04 lasso 8 0.03 2.8e-04 6.3 5.2 2.2e-07 0.32 0.29 0.03 FALSE