TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Whole body fat mass
:
←
→
chr13:27,315,078-28,717,392
Best TWAS P=2.69e-09 · Best GWAS P=1.34e-11 conditioned to 0.022
27.4M
27.6M
27.8M
28M
28.2M
28.4M
28.6M
28.8M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Nerve Tibial
AL137059.1
0.10
0.02
lasso
3
0.03
0.0029
4.4
-5.9
2.7e-09
0.71
0.02
0.94
TRUE
3
The Cancer Genome Atlas
Brain Lower Grade Glioma
GTF3A
0.03
0.00
enet
8
0.01
0.0228
1.5
5.6
2.6e-08
-0.63
0.01
0.84
TRUE
1
GTEx
Muscle Skeletal
MTIF3
0.12
0.03
lasso
5
0.03
0.0012
-5.1
-5.3
1.4e-07
0.74
0.28
0.56
FALSE