Best TWAS P=2.69e-09 · Best GWAS P=1.34e-11 conditioned to 0.022
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Muscle Skeletal | MTIF3 | 0.12 | 0.03 | lasso | 5 | 0.03 | 0.0012 | -5.1 | -5.3 | 1.4e-07 | 0.74 | 0.28 | 0.56 | FALSE |
| 2 | GTEx | Nerve Tibial | AL137059.1 | 0.10 | 0.02 | lasso | 3 | 0.03 | 0.0029 | 4.4 | -5.9 | 2.7e-09 | 0.71 | 0.02 | 0.94 | TRUE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | GTF3A | 0.03 | 0.00 | enet | 8 | 0.01 | 0.0228 | 1.5 | 5.6 | 2.6e-08 | -0.63 | 0.01 | 0.84 | TRUE |