Best TWAS P=2.94e-09 · Best GWAS P=3.36e-13 conditioned to 0.000505
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | NEO1 | 0.20 | 0.13 | lasso | 7 | 0.17 | 1.1e-10 | -5.9 | 5.6 | 2.3e-08 | -0.45 | 0.82 | 0.18 | FALSE |
| 2 | GTEx | Nerve Tibial | NEO1 | 0.07 | 0.09 | lasso | 2 | 0.09 | 3.9e-07 | -5.9 | -5.9 | 2.9e-09 | 0.45 | 0.61 | 0.35 | TRUE |
| 3 | GTEx | Pituitary | BBS4 | 0.27 | 0.02 | enet | 21 | 0.05 | 2.1e-02 | -5.2 | -5.5 | 4.7e-08 | 0.69 | 0.06 | 0.44 | TRUE |
| 4 | GTEx | Testis | ADPGK-AS1 | 0.17 | 0.05 | lasso | 4 | 0.03 | 1.3e-02 | -4.2 | 5.9 | 3.2e-09 | -0.72 | 0.02 | 0.88 | FALSE |