[Hub]/) : Traits : Whole body fat mass : ← →

chr15:83,632,164-86,489,699

Best TWAS P=6.43e-13 · Best GWAS P=7.06e-18 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
46	GTEx	Skin Sun Exposed Lower leg	AC103965.1	0.33	0.17	enet	24	0.23	4.8e-19	5.12	-7.2	6.4e-13	0.50	1.00	0.00	TRUE
52	GTEx	Whole Blood	GOLGA6L4	0.12	0.08	enet	16	0.11	2.1e-10	-5.05	-6.8	1.2e-11	0.58	0.80	0.20	TRUE
21	GTEx	Breast Mammary Tissue (Male)	GOLGA6L4	0.23	0.07	lasso	2	0.12	8.3e-04	-6.36	-6.3	2.2e-10	0.57	0.07	0.33	TRUE
31	GTEx	Esophagus Muscularis	UBE2Q2P1	0.34	0.03	lasso	7	0.15	1.9e-09	2.58	6.3	2.2e-10	-0.42	0.34	0.28	TRUE
47	GTEx	Small Intestine Terminal Ileum	RP11-182J1.14	0.26	0.01	enet	27	0.12	1.3e-03	-7.74	6.3	2.4e-10	-0.37	0.06	0.17	TRUE
4	GTEx	Adipose Subcutaneous	CSPG4P11	0.19	0.17	lasso	5	0.20	7.9e-16	5.18	-6.2	4.8e-10	0.38	1.00	0.00	TRUE
54	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	UBE2Q2P1	0.10	0.00	blup	22	0.03	1.9e-02	-5.45	6.1	1.3e-09	-0.40	0.00	0.42	TRUE
5	GTEx	Adipose Visceral Omentum	GOLGA6L3	0.23	0.05	lasso	5	0.07	2.2e-04	-6.03	-5.3	9.7e-08	0.37	0.00	1.00	TRUE
48	GTEx	Spleen	GOLGA6L4	0.55	0.20	enet	19	0.40	2.6e-11	-6.06	-7.1	1.6e-12	0.54	0.87	0.04	FALSE
23	GTEx	Cells Transformed fibroblasts	AC103965.1	0.15	0.09	lasso	7	0.11	1.3e-08	5.18	-7.0	2.8e-12	0.56	0.68	0.31	FALSE
22	GTEx	Breast Mammary Tissue (Male)	AC103965.1	0.24	0.14	lasso	4	0.11	1.4e-03	4.92	-6.9	5.3e-12	0.55	0.07	0.58	FALSE
2	CommonMind	Brain Pre-frontal Cortex	LOC388152	0.14	0.14	enet	20	0.18	6.7e-22	5.16	-6.9	5.6e-12	0.52	1.00	0.00	FALSE
26	GTEx	Colon Transverse	AC103965.1	0.15	0.07	enet	33	0.06	7.1e-04	-6.06	-6.9	6.2e-12	0.50	0.10	0.53	FALSE
39	GTEx	Pancreas	RP11-182J1.16	0.08	-0.01	enet	11	-0.01	7.9e-01	-6.06	-6.9	6.6e-12	0.62	0.03	0.52	FALSE
15	GTEx	Brain Cerebellum	AC103965.1	0.13	0.02	enet	21	0.01	2.1e-01	5.18	-6.8	8.6e-12	0.53	0.08	0.43	FALSE
16	GTEx	Brain Cortex	GOLGA6L4	0.42	0.21	lasso	7	0.28	2.8e-08	-6.36	-6.7	1.9e-11	0.65	0.17	0.75	FALSE
41	GTEx	Prostate	RP11-182J1.16	0.24	0.06	enet	27	0.08	6.2e-03	0.60	-6.7	2.1e-11	0.48	0.07	0.31	FALSE
42	GTEx	Prostate	CSPG4P11	0.34	0.07	enet	13	0.18	2.3e-05	-2.89	-6.7	2.8e-11	0.42	0.06	0.70	FALSE
36	GTEx	Nerve Tibial	AC103965.1	0.20	0.22	enet	17	0.27	5.1e-19	5.12	-6.6	3.0e-11	0.49	1.00	0.00	FALSE
29	GTEx	Esophagus Mucosa	RP11-182J1.16	0.20	0.05	lasso	5	0.10	1.8e-07	4.97	-6.5	8.3e-11	0.46	0.89	0.02	FALSE
30	GTEx	Esophagus Mucosa	CSPG4P11	0.21	0.01	enet	28	0.08	3.7e-06	-6.06	-6.5	1.0e-10	0.56	0.61	0.32	FALSE
3	GTEx	Adipose Subcutaneous	AC103965.1	0.24	0.14	lasso	6	0.15	2.6e-12	5.18	-6.4	1.3e-10	0.40	1.00	0.00	FALSE
33	GTEx	Lung	AC103965.1	0.20	0.14	lasso	4	0.16	1.8e-12	5.12	-6.4	1.3e-10	0.42	1.00	0.00	FALSE
37	GTEx	Ovary	AC103965.1	0.27	0.22	lasso	3	0.24	1.6e-06	5.18	-6.4	1.9e-10	0.43	0.34	0.12	FALSE
13	GTEx	Artery Tibial	CSPG4P11	0.16	0.24	lasso	4	0.23	3.0e-18	5.12	-6.2	4.8e-10	0.41	1.00	0.00	FALSE
11	GTEx	Artery Tibial	SCAND2P	0.12	0.05	enet	16	0.08	8.7e-07	-3.36	-6.2	5.6e-10	0.38	0.44	0.36	FALSE
27	GTEx	Colon Transverse	CSPG4P11	0.10	0.10	lasso	4	0.08	1.2e-04	-6.06	-6.2	6.3e-10	0.40	0.25	0.04	FALSE
19	GTEx	Brain Nucleus accumbens basal ganglia	AC103965.1	0.29	0.23	enet	21	0.27	6.9e-08	4.87	-6.2	7.4e-10	0.45	0.84	0.10	FALSE
28	GTEx	Esophagus Mucosa	AC103965.1	0.20	0.19	enet	47	0.16	8.4e-11	5.12	-6.2	7.4e-10	0.47	1.00	0.00	FALSE
50	GTEx	Thyroid	AC103965.1	0.30	0.25	lasso	7	0.25	1.8e-19	5.18	-6.1	1.2e-09	0.37	1.00	0.00	FALSE
40	GTEx	Pituitary	AC103965.1	0.30	0.16	enet	10	0.24	8.4e-07	5.11	-6.0	1.9e-09	0.52	0.28	0.46	FALSE
12	GTEx	Artery Tibial	AC103965.1	0.27	0.26	enet	31	0.30	1.8e-23	5.12	-5.9	2.9e-09	0.41	1.00	0.00	FALSE
32	GTEx	Esophagus Muscularis	AC103965.1	0.18	0.14	enet	16	0.14	7.6e-09	4.92	-5.9	3.3e-09	0.40	1.00	0.00	FALSE
17	GTEx	Brain Cortex	AC103965.1	0.17	0.19	lasso	3	0.16	4.3e-05	4.92	-5.9	4.8e-09	0.40	0.21	0.44	FALSE
43	GTEx	Skin Not Sun Exposed Suprapubic	AC103965.1	0.23	0.15	lasso	8	0.19	1.9e-10	5.18	-5.8	6.0e-09	0.37	0.96	0.02	FALSE
45	GTEx	Skin Sun Exposed Lower leg	ZSCAN2	0.08	0.02	enet	13	0.03	1.4e-03	-6.04	5.7	1.2e-08	-0.34	0.38	0.07	FALSE
55	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	UBE2Q2P1	0.03	0.03	lasso	3	0.02	9.2e-04	5.18	5.7	1.2e-08	-0.36	0.04	0.21	FALSE
7	GTEx	Artery Aorta	UBE2Q2P1	0.15	0.00	enet	21	0.05	8.4e-04	-3.08	5.7	1.3e-08	-0.46	0.26	0.15	FALSE
38	GTEx	Pancreas	AC103965.1	0.29	0.23	lasso	9	0.18	2.8e-08	5.18	-5.6	1.7e-08	0.39	1.00	0.00	FALSE
18	GTEx	Brain Nucleus accumbens basal ganglia	GOLGA6L4	0.21	0.04	lasso	5	0.09	2.3e-03	-6.95	-5.6	2.0e-08	0.55	0.06	0.18	FALSE
14	GTEx	Brain Caudate basal ganglia	AC103965.1	0.28	0.25	lasso	7	0.25	6.7e-08	4.92	-5.6	2.3e-08	0.37	0.82	0.04	FALSE
35	GTEx	Nerve Tibial	UBE2Q2P1	0.13	0.01	enet	37	0.04	1.3e-03	5.16	5.6	2.8e-08	-0.20	0.10	0.40	FALSE
34	GTEx	Muscle Skeletal	NMB	0.07	0.00	enet	23	0.00	9.9e-02	-3.68	-5.5	3.2e-08	0.39	0.11	0.46	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ADAMTSL3	0.10	0.04	lasso	4	0.04	8.7e-06	-6.74	-5.5	3.6e-08	0.56	0.23	0.09	FALSE
51	GTEx	Thyroid	RP11-182J1.16	0.10	0.02	lasso	7	0.05	1.3e-04	-6.70	-5.5	4.8e-08	0.56	0.38	0.32	FALSE
56	The Cancer Genome Atlas	Soft Tissue Sarcoma	GOLGA6L5	0.09	0.08	enet	4	0.09	5.2e-06	-2.28	-5.5	4.9e-08	0.44	0.01	0.84	FALSE
53	The Cancer Genome Atlas	Brain Lower Grade Glioma	UBE2Q2P1	0.07	0.04	blup	22	0.06	1.8e-07	5.18	5.4	8.4e-08	-0.37	0.66	0.28	FALSE
24	GTEx	Colon Sigmoid	RP11-182J1.14	0.31	0.29	lasso	9	0.30	2.7e-11	4.97	5.3	1.2e-07	-0.36	1.00	0.00	FALSE
44	GTEx	Skin Not Sun Exposed Suprapubic	RP11-182J1.16	0.10	0.01	enet	13	0.04	3.1e-03	0.89	-5.2	1.5e-07	0.40	0.37	0.06	FALSE
25	GTEx	Colon Transverse	GOLGA6L3	0.18	0.17	lasso	4	0.14	2.2e-07	-6.03	-5.2	1.8e-07	0.36	0.00	1.00	FALSE
8	GTEx	Artery Aorta	AC103965.1	0.10	0.12	lasso	3	0.10	3.9e-06	5.16	-5.2	2.2e-07	0.30	0.92	0.05	FALSE
6	GTEx	Adrenal Gland	CSPG4P11	0.14	-0.01	enet	15	0.04	1.7e-02	5.18	-5.2	2.4e-07	0.22	0.15	0.05	FALSE
10	GTEx	Artery Aorta	CSPG4P11	0.11	0.10	lasso	4	0.08	3.1e-05	5.18	-5.2	2.4e-07	0.30	0.92	0.01	FALSE
9	GTEx	Artery Aorta	RP11-182J1.16	0.11	0.12	lasso	3	0.11	1.6e-06	5.18	-5.1	2.8e-07	0.28	0.94	0.01	FALSE
20	GTEx	Breast Mammary Tissue	AC103965.1	0.13	0.11	lasso	1	0.13	2.9e-07	5.12	-5.1	3.1e-07	0.31	0.92	0.02	FALSE
49	GTEx	Testis	RP11-182J1.14	0.10	0.19	lasso	1	0.17	6.7e-08	5.12	5.1	3.1e-07	-0.31	0.94	0.00	FALSE