[Hub]/) : Traits : Whole body fat mass :

chr15:83,632,164-86,489,699

Best TWAS P=6.43e-13 · Best GWAS P=7.06e-18 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ADAMTSL3 0.10 0.04 lasso 4 0.04 8.7e-06 -6.74 -5.5 3.6e-08 0.56 0.23 0.09 FALSE
2 CommonMind Brain Pre-frontal Cortex LOC388152 0.14 0.14 enet 20 0.18 6.7e-22 5.16 -6.9 5.6e-12 0.52 1.00 0.00 FALSE
3 GTEx Adipose Subcutaneous AC103965.1 0.24 0.14 lasso 6 0.15 2.6e-12 5.18 -6.4 1.3e-10 0.40 1.00 0.00 FALSE
4 GTEx Adipose Subcutaneous CSPG4P11 0.19 0.17 lasso 5 0.20 7.9e-16 5.18 -6.2 4.8e-10 0.38 1.00 0.00 TRUE
5 GTEx Adipose Visceral Omentum GOLGA6L3 0.23 0.05 lasso 5 0.07 2.2e-04 -6.03 -5.3 9.7e-08 0.37 0.00 1.00 TRUE
6 GTEx Adrenal Gland CSPG4P11 0.14 -0.01 enet 15 0.04 1.7e-02 5.18 -5.2 2.4e-07 0.22 0.15 0.05 FALSE
7 GTEx Artery Aorta UBE2Q2P1 0.15 0.00 enet 21 0.05 8.4e-04 -3.08 5.7 1.3e-08 -0.46 0.26 0.15 FALSE
8 GTEx Artery Aorta AC103965.1 0.10 0.12 lasso 3 0.10 3.9e-06 5.16 -5.2 2.2e-07 0.30 0.92 0.05 FALSE
9 GTEx Artery Aorta RP11-182J1.16 0.11 0.12 lasso 3 0.11 1.6e-06 5.18 -5.1 2.8e-07 0.28 0.94 0.01 FALSE
10 GTEx Artery Aorta CSPG4P11 0.11 0.10 lasso 4 0.08 3.1e-05 5.18 -5.2 2.4e-07 0.30 0.92 0.01 FALSE
11 GTEx Artery Tibial SCAND2P 0.12 0.05 enet 16 0.08 8.7e-07 -3.36 -6.2 5.6e-10 0.38 0.44 0.36 FALSE
12 GTEx Artery Tibial AC103965.1 0.27 0.26 enet 31 0.30 1.8e-23 5.12 -5.9 2.9e-09 0.41 1.00 0.00 FALSE
13 GTEx Artery Tibial CSPG4P11 0.16 0.24 lasso 4 0.23 3.0e-18 5.12 -6.2 4.8e-10 0.41 1.00 0.00 FALSE
14 GTEx Brain Caudate basal ganglia AC103965.1 0.28 0.25 lasso 7 0.25 6.7e-08 4.92 -5.6 2.3e-08 0.37 0.82 0.04 FALSE
15 GTEx Brain Cerebellum AC103965.1 0.13 0.02 enet 21 0.01 2.1e-01 5.18 -6.8 8.6e-12 0.53 0.08 0.43 FALSE
16 GTEx Brain Cortex GOLGA6L4 0.42 0.21 lasso 7 0.28 2.8e-08 -6.36 -6.7 1.9e-11 0.65 0.17 0.75 FALSE
17 GTEx Brain Cortex AC103965.1 0.17 0.19 lasso 3 0.16 4.3e-05 4.92 -5.9 4.8e-09 0.40 0.21 0.44 FALSE
18 GTEx Brain Nucleus accumbens basal ganglia GOLGA6L4 0.21 0.04 lasso 5 0.09 2.3e-03 -6.95 -5.6 2.0e-08 0.55 0.06 0.18 FALSE
19 GTEx Brain Nucleus accumbens basal ganglia AC103965.1 0.29 0.23 enet 21 0.27 6.9e-08 4.87 -6.2 7.4e-10 0.45 0.84 0.10 FALSE
20 GTEx Breast Mammary Tissue AC103965.1 0.13 0.11 lasso 1 0.13 2.9e-07 5.12 -5.1 3.1e-07 0.31 0.92 0.02 FALSE
21 GTEx Breast Mammary Tissue (Male) GOLGA6L4 0.23 0.07 lasso 2 0.12 8.3e-04 -6.36 -6.3 2.2e-10 0.57 0.07 0.33 TRUE
22 GTEx Breast Mammary Tissue (Male) AC103965.1 0.24 0.14 lasso 4 0.11 1.4e-03 4.92 -6.9 5.3e-12 0.55 0.07 0.58 FALSE
23 GTEx Cells Transformed fibroblasts AC103965.1 0.15 0.09 lasso 7 0.11 1.3e-08 5.18 -7.0 2.8e-12 0.56 0.68 0.31 FALSE
24 GTEx Colon Sigmoid RP11-182J1.14 0.31 0.29 lasso 9 0.30 2.7e-11 4.97 5.3 1.2e-07 -0.36 1.00 0.00 FALSE
25 GTEx Colon Transverse GOLGA6L3 0.18 0.17 lasso 4 0.14 2.2e-07 -6.03 -5.2 1.8e-07 0.36 0.00 1.00 FALSE
26 GTEx Colon Transverse AC103965.1 0.15 0.07 enet 33 0.06 7.1e-04 -6.06 -6.9 6.2e-12 0.50 0.10 0.53 FALSE
27 GTEx Colon Transverse CSPG4P11 0.10 0.10 lasso 4 0.08 1.2e-04 -6.06 -6.2 6.3e-10 0.40 0.25 0.04 FALSE
28 GTEx Esophagus Mucosa AC103965.1 0.20 0.19 enet 47 0.16 8.4e-11 5.12 -6.2 7.4e-10 0.47 1.00 0.00 FALSE
29 GTEx Esophagus Mucosa RP11-182J1.16 0.20 0.05 lasso 5 0.10 1.8e-07 4.97 -6.5 8.3e-11 0.46 0.89 0.02 FALSE
30 GTEx Esophagus Mucosa CSPG4P11 0.21 0.01 enet 28 0.08 3.7e-06 -6.06 -6.5 1.0e-10 0.56 0.61 0.32 FALSE
31 GTEx Esophagus Muscularis UBE2Q2P1 0.34 0.03 lasso 7 0.15 1.9e-09 2.58 6.3 2.2e-10 -0.42 0.34 0.28 TRUE
32 GTEx Esophagus Muscularis AC103965.1 0.18 0.14 enet 16 0.14 7.6e-09 4.92 -5.9 3.3e-09 0.40 1.00 0.00 FALSE
33 GTEx Lung AC103965.1 0.20 0.14 lasso 4 0.16 1.8e-12 5.12 -6.4 1.3e-10 0.42 1.00 0.00 FALSE
34 GTEx Muscle Skeletal NMB 0.07 0.00 enet 23 0.00 9.9e-02 -3.68 -5.5 3.2e-08 0.39 0.11 0.46 FALSE
35 GTEx Nerve Tibial UBE2Q2P1 0.13 0.01 enet 37 0.04 1.3e-03 5.16 5.6 2.8e-08 -0.20 0.10 0.40 FALSE
36 GTEx Nerve Tibial AC103965.1 0.20 0.22 enet 17 0.27 5.1e-19 5.12 -6.6 3.0e-11 0.49 1.00 0.00 FALSE
37 GTEx Ovary AC103965.1 0.27 0.22 lasso 3 0.24 1.6e-06 5.18 -6.4 1.9e-10 0.43 0.34 0.12 FALSE
38 GTEx Pancreas AC103965.1 0.29 0.23 lasso 9 0.18 2.8e-08 5.18 -5.6 1.7e-08 0.39 1.00 0.00 FALSE
39 GTEx Pancreas RP11-182J1.16 0.08 -0.01 enet 11 -0.01 7.9e-01 -6.06 -6.9 6.6e-12 0.62 0.03 0.52 FALSE
40 GTEx Pituitary AC103965.1 0.30 0.16 enet 10 0.24 8.4e-07 5.11 -6.0 1.9e-09 0.52 0.28 0.46 FALSE
41 GTEx Prostate RP11-182J1.16 0.24 0.06 enet 27 0.08 6.2e-03 0.60 -6.7 2.1e-11 0.48 0.07 0.31 FALSE
42 GTEx Prostate CSPG4P11 0.34 0.07 enet 13 0.18 2.3e-05 -2.89 -6.7 2.8e-11 0.42 0.06 0.70 FALSE
43 GTEx Skin Not Sun Exposed Suprapubic AC103965.1 0.23 0.15 lasso 8 0.19 1.9e-10 5.18 -5.8 6.0e-09 0.37 0.96 0.02 FALSE
44 GTEx Skin Not Sun Exposed Suprapubic RP11-182J1.16 0.10 0.01 enet 13 0.04 3.1e-03 0.89 -5.2 1.5e-07 0.40 0.37 0.06 FALSE
45 GTEx Skin Sun Exposed Lower leg ZSCAN2 0.08 0.02 enet 13 0.03 1.4e-03 -6.04 5.7 1.2e-08 -0.34 0.38 0.07 FALSE
46 GTEx Skin Sun Exposed Lower leg AC103965.1 0.33 0.17 enet 24 0.23 4.8e-19 5.12 -7.2 6.4e-13 0.50 1.00 0.00 TRUE
47 GTEx Small Intestine Terminal Ileum RP11-182J1.14 0.26 0.01 enet 27 0.12 1.3e-03 -7.74 6.3 2.4e-10 -0.37 0.06 0.17 TRUE
48 GTEx Spleen GOLGA6L4 0.55 0.20 enet 19 0.40 2.6e-11 -6.06 -7.1 1.6e-12 0.54 0.87 0.04 FALSE
49 GTEx Testis RP11-182J1.14 0.10 0.19 lasso 1 0.17 6.7e-08 5.12 5.1 3.1e-07 -0.31 0.94 0.00 FALSE
50 GTEx Thyroid AC103965.1 0.30 0.25 lasso 7 0.25 1.8e-19 5.18 -6.1 1.2e-09 0.37 1.00 0.00 FALSE
51 GTEx Thyroid RP11-182J1.16 0.10 0.02 lasso 7 0.05 1.3e-04 -6.70 -5.5 4.8e-08 0.56 0.38 0.32 FALSE
52 GTEx Whole Blood GOLGA6L4 0.12 0.08 enet 16 0.11 2.1e-10 -5.05 -6.8 1.2e-11 0.58 0.80 0.20 TRUE
53 The Cancer Genome Atlas Brain Lower Grade Glioma UBE2Q2P1 0.07 0.04 blup 22 0.06 1.8e-07 5.18 5.4 8.4e-08 -0.37 0.66 0.28 FALSE
54 The Cancer Genome Atlas Liver Hepatocellular Carcinoma UBE2Q2P1 0.10 0.00 blup 22 0.03 1.9e-02 -5.45 6.1 1.3e-09 -0.40 0.00 0.42 TRUE
55 The Cancer Genome Atlas Lung Squamous Cell Carcinoma UBE2Q2P1 0.03 0.03 lasso 3 0.02 9.2e-04 5.18 5.7 1.2e-08 -0.36 0.04 0.21 FALSE
56 The Cancer Genome Atlas Soft Tissue Sarcoma GOLGA6L5 0.09 0.08 enet 4 0.09 5.2e-06 -2.28 -5.5 4.9e-08 0.44 0.01 0.84 FALSE