[Hub]/) : Traits : Whole body fat mass : ← →

chr4:47,802,595-53,598,975

Best TWAS P=1.69e-10 · Best GWAS P=1.22e-09 conditioned to 0.304

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SGCB 0.02 0.02 enet 21 0.01 9.7e-03 5.5 5.2 2.6e-07 0.69 0.05 0.85 FALSE
2 GTEx Breast Mammary Tissue DCUN1D4 0.08 0.02 enet 11 0.04 2.4e-03 6.0 5.8 6.2e-09 0.89 0.04 0.91 FALSE
3 GTEx Breast Mammary Tissue (Female) DCUN1D4 0.02 0.03 lasso 1 0.02 8.2e-02 6.0 6.0 2.6e-09 0.96 0.02 0.22 FALSE
4 GTEx Cells Transformed fibroblasts DCUN1D4 0.05 0.04 enet 15 0.04 7.8e-04 5.4 5.4 5.8e-08 0.85 0.05 0.89 FALSE
5 GTEx Nerve Tibial DCUN1D4 0.10 0.09 lasso 3 0.10 6.8e-08 5.4 5.8 5.4e-09 0.93 0.07 0.93 FALSE
6 GTEx Ovary FRYL 0.12 -0.01 enet 21 0.03 7.2e-02 5.2 5.6 1.9e-08 0.62 0.07 0.51 FALSE
7 GTEx Testis DCUN1D4 0.19 0.17 enet 14 0.16 8.7e-08 5.4 5.6 2.8e-08 0.84 0.08 0.92 FALSE
8 GTEx Thyroid DCUN1D4 0.03 0.05 lasso 1 0.04 2.4e-04 6.0 6.0 2.6e-09 0.96 0.03 0.94 FALSE
9 ROSMAP Brain Pre-frontal Cortex SGCB 0.03 0.03 enet 9 0.03 7.0e-05 5.6 6.4 1.7e-10 0.87 0.04 0.96 TRUE
10 The Cancer Genome Atlas Colon Adenocarcinoma LRRC66 0.07 0.03 lasso 3 0.05 8.0e-04 5.1 -5.2 2.2e-07 -0.62 0.03 0.39 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma FRYL 0.03 0.03 enet 8 0.03 3.2e-04 4.8 5.2 1.8e-07 0.40 0.04 0.84 FALSE