TWAS hub - RNF4

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1150	0.0370	5.6e-05	0.016	0.046	0.031	0.047	0.026	4.2e-03	2.4e-06	1.1e-04	1.8e-06	3.4e-04
2	GTEx	Artery Tibial	0.1284	0.0470	3.9e-03	0.040	NA	0.053	NA	0.050	4.2e-04	NA	5.2e-05	NA	9.0e-05
3	GTEx	Brain Caudate basal ganglia	0.3210	0.0990	1.9e-03	0.040	NA	0.071	NA	0.043	2.7e-02	NA	4.4e-03	NA	2.2e-02
4	GTEx	Cells Transformed fibroblasts	0.1720	0.0470	4.6e-06	0.126	NA	0.135	NA	0.134	1.1e-09	NA	2.6e-10	NA	3.3e-10
5	GTEx	Esophagus Mucosa	0.1160	0.0450	1.4e-03	0.012	NA	0.018	NA	0.017	5.2e-02	NA	2.0e-02	NA	2.4e-02
6	GTEx	Esophagus Muscularis	0.1470	0.0490	9.2e-04	0.066	NA	0.072	NA	0.067	7.3e-05	NA	3.7e-05	NA	6.8e-05
7	GTEx	Lung	0.1288	0.0478	2.8e-03	0.073	NA	0.012	NA	0.045	3.1e-06	NA	3.8e-02	NA	2.3e-04
8	GTEx	Nerve Tibial	0.1489	0.0535	1.8e-03	0.009	NA	0.028	NA	0.016	7.1e-02	NA	4.1e-03	NA	2.5e-02
9	GTEx	Thyroid	0.1460	0.0440	3.5e-04	0.033	NA	0.037	NA	0.039	1.5e-03	NA	7.3e-04	NA	6.0e-04
10	METSIM	Adipose	0.0372	0.0181	9.2e-03	0.027	-0.001	0.003	0.002	0.004	4.8e-05	4.7e-01	1.0e-01	1.3e-01	6.3e-02
11	ROSMAP	Brain Pre-frontal Cortex	0.1626	0.0386	2.9e-10	0.076	0.099	0.115	0.108	0.100	5.7e-10	1.2e-12	1.4e-14	8.8e-14	8.2e-13
12	YFS	Blood	0.0724	0.0159	0.0e+00	0.075	0.070	0.068	0.074	0.071	2.5e-23	9.6e-22	2.2e-21	4.8e-23	2.6e-22
13	TCGA	Cervical Squamous Cell Carcinoma	0.1360	0.0590	7.9e-04	0.019	0.068	0.024	NA	0.028	3.9e-02	3.1e-04	2.2e-02	NA	1.5e-02
14	TCGA	Kidney Renal Clear Cell Carcinoma	0.0378	0.0203	6.0e-03	0.005	0.002	0.001	NA	0.000	8.5e-02	1.9e-01	2.3e-01	NA	2.8e-01
15	TCGA	Brain Lower Grade Glioma	0.0627	0.0253	2.1e-05	0.021	0.043	0.039	NA	0.038	1.7e-03	1.1e-05	2.8e-05	NA	3.8e-05
16	TCGA	Lung Squamous Cell Carcinoma	0.0329	0.0178	9.2e-03	-0.001	0.011	0.006	NA	0.000	4.7e-01	1.7e-02	5.4e-02	NA	2.8e-01
17	TCGA	Prostate Adenocarcinoma	0.0593	0.0254	2.3e-05	0.071	0.059	0.066	NA	0.067	6.8e-08	8.5e-07	1.9e-07	NA	1.7e-07
18	TCGA	Thyroid Carcinoma	0.0610	0.0270	3.0e-05	0.039	0.054	0.062	NA	0.057	9.9e-05	5.0e-06	1.1e-06	NA	3.3e-06

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Frequency of tiredness / lethargy in last 2 weeks	7.1	11.6	21.2	-2.0	3.2	4.5	4.2	4.4	4.6	3.9	2.2	2.9	3.8	2.4	2.4	3.0	3.3	3.4	1.4	3.9	3.6
Overall health rating	6.7	14.4	26.3	-1.1	3.9	4.6	5.0	3.8	5.1	4.4	2.7	3.2	4.3	2.0	2.1	4.3	2.7	3.6	3.9	4.3	4.3
Age when periods started (menarche)	6.3	15.2	23.2	-1.4	-4.2	-4.6	-4.7	-3.9	-4.6	-4.0	-2.5	-4.1	-4.0	-2.8	-3.3	-4.8	-3.2	-4.0	-3.7	-4.0	-4.6
Unable to work because of sickness or disability	6.2	8.1	14.8	-1.5	2.8	2.9	3.1	3.1	3.8	3.7	1.5	3.2	3.5	0.2	2.2	2.0	3.1	2.8	2.2	3.6	3.1
Wears glasses or contact lenses	6.1	7.0	11.7	0.9	-3.3	-2.8	-3.0	-2.1	-3.4	-3.4	-0.9	-2.5	-3.3	0.2	-3.3	-3.4	-1.0	-1.9	-2.1	-3.3	-3.1
Leg pain on walking	6.0	7.5	13.5	-1.0	2.5	2.9	3.5	2.2	3.2	2.4	1.8	3.3	2.7	1.0	2.8	3.7	2.4	3.2	2.8	2.3	3.6
Age at first live birth	5.9	10.5	17.1	0.1	-3.8	-3.5	-3.7	-3.4	-4.1	-3.4	-1.4	-3.2	-3.5	-2.2	-2.8	-3.9	-2.2	-3.6	-3.3	-3.3	-4.1
Alcohol intake frequency.	5.7	13.3	22.9	1.1	3.3	4.4	4.7	3.9	4.8	4.3	1.6	3.3	4.2	1.9	1.6	3.9	3.1	3.9	4.0	4.3	4.2
Mother’s age at death	5.7	7.1	12.3	0.5	-3.5	-3.5	-3.4	-2.6	-3.2	-2.2	-2.9	-2.3	-2.3	-2.1	-1.7	-3.5	-1.5	-2.8	-2.6	-2.2	-3.1
Vitamin and mineral supplements	5.5	7.4	12.0	-0.2	3.3	3.5	3.1	3.3	3.3	2.6	3.0	2.3	2.5	2.2	0.5	2.6	3.0	3.1	2.8	2.7	2.7
Multivitamins +/- minerals	4.9	6.2	10.8	0.2	-3.1	-3.3	-2.9	-3.1	-3.2	-2.6	-2.6	-2.1	-2.5	-1.6	-0.9	-2.4	-2.4	-2.6	-2.2	-2.6	-2.6
Medication: Co-codamol	4.8	5.5	12.1	-0.1	3.5	3.4	2.4	3.4	3.3	2.5	1.4	1.1	2.4	2.4	0.1	2.5	2.0	2.2	1.0	2.5	2.3
Frequency of tenseness / restlessness in last 2 weeks	4.4	6.8	11.2	-0.6	2.0	3.0	3.1	3.2	3.1	3.0	0.5	2.4	3.1	1.8	2.5	2.9	2.9	2.7	0.4	3.1	3.4
Smoking status: Previous	4.4	6.6	12.2	0.3	-1.4	-3.2	-2.6	-3.1	-3.5	-3.3	-0.0	-2.4	-3.1	-1.6	-2.3	-1.9	-2.4	-2.4	-2.8	-3.3	-2.9
Supplements: Glucosamine	4.3	5.6	11.6	0.1	-3.4	-2.8	-2.6	-2.6	-3.0	-2.9	-2.2	-1.8	-2.6	-1.5	-1.1	-2.5	-1.7	-1.9	-2.1	-2.8	-2.5
Bipolar Disorder (2011)	4.2	4.0	8.3	0.3	1.4	2.0	2.5	2.4	2.2	2.2	0.8	1.9	2.1	2.3	1.5	1.6	2.7	2.9	2.3	2.3	0.0
Townsend deprivation index at recruitment	4.2	5.9	14.8	1.0	3.8	2.7	2.8	2.7	3.0	2.3	1.7	2.1	2.2	1.6	1.9	2.7	1.9	2.6	2.1	2.3	2.8
Number of full brothers	3.7	4.6	9.8	-1.2	1.6	2.8	2.2	3.1	2.9	2.8	1.2	1.6	2.6	2.0	-0.1	1.1	2.5	2.3	1.4	2.8	2.0
Supplements: Vitamin C	3.7	4.4	8.4	-1.0	-1.9	-2.6	-2.6	-2.6	-2.3	-1.4	-2.0	-1.3	-1.3	-2.9	0.3	-2.1	-2.7	-2.8	-2.1	-1.5	-2.1
Alzheimer’s Disease (in mother)	3.6	4.3	8.1	-0.4	-2.1	-2.9	-2.0	-2.4	-2.6	-2.2	-1.2	-1.9	-2.2	-2.2	-0.3	-1.9	-2.5	-2.4	-1.3	-2.2	-2.5
Pain all over the body in last month	3.6	3.8	6.8	-0.2	1.6	1.8	2.4	2.3	2.1	2.6	1.4	2.1	2.5	1.8	1.5	1.1	1.8	1.9	1.4	2.6	2.4
Cholesterol lowering medication	3.6	5.4	9.2	-1.6	-1.9	-2.2	-2.1	-2.2	-2.5	-3.0	-1.3	-2.9	-3.0	-1.2	-1.6	-1.7	-2.8	-2.2	-2.5	-3.0	-2.7
Medication: Atenolol	3.5	4.3	11.4	1.4	1.7	1.2	1.9	2.2	1.0	1.9	2.2	3.4	2.4	2.4	-0.3	0.9	3.1	3.1	1.0	2.0	2.5
Frequency of unenthusiasm / disinterest in last 2 weeks	3.3	4.3	7.1	-0.4	1.9	2.5	2.4	2.6	2.3	2.2	1.2	1.9	2.2	1.8	1.8	2.4	2.3	2.3	0.0	2.2	2.7
Worry too long after embarrassment	3.3	5.5	15.1	-0.8	-3.9	-2.7	-2.2	-2.0	-3.0	-2.1	-3.5	-1.6	-2.0	-1.3	-1.2	-2.8	-1.4	-2.1	-2.7	-2.0	-2.4
Chest pain or discomfort	3.3	4.8	9.4	0.5	1.6	3.1	2.9	2.6	2.5	2.2	1.2	2.0	2.2	1.9	0.7	1.7	2.8	2.9	0.9	2.2	2.9
Medication: Atorvastatin	3.3	4.0	9.1	-1.4	-0.1	-1.5	-2.0	-1.6	-1.9	-2.3	0.2	-3.0	-2.4	-0.6	-2.5	-1.9	-1.9	-2.0	-2.6	-2.3	-2.8
Alcohol drinker status: Previous	3.3	3.8	6.5	0.3	1.7	1.7	2.4	2.4	1.7	2.5	1.2	2.3	2.4	1.8	1.1	1.0	1.8	2.1	1.8	2.5	2.4
Health satisfaction	3.2	4.1	9.1	0.1	3.0	2.8	2.2	2.3	3.0	2.0	1.6	1.1	2.0	1.4	0.2	2.3	1.6	2.1	1.7	2.0	2.2
Illness, injury, bereavement, stress in last 2 years	3.2	3.9	7.3	0.3	-1.4	-2.5	-2.0	-2.7	-2.3	-2.3	-0.8	-1.9	-2.1	-2.3	-1.1	-1.1	-2.3	-2.6	-0.9	-2.3	-2.4
Supplements: Fish oil (including cod liver oil)	3.1	4.0	10.2	-0.2	-3.0	-3.0	-2.2	-2.0	-2.9	-1.5	-1.7	-0.8	-1.4	-1.9	-0.3	-3.2	-1.2	-1.7	-2.3	-1.5	-1.9
Ovarian Cancer	3.0	4.0	10.2	0.8	1.2	1.7	1.6	2.1	1.5	2.2	1.1	3.1	2.5	2.4	0.3	-0.6	3.2	2.8	0.7	2.3	2.5
Shortness of breath walking on level ground	2.9	3.5	9.7	0.7	-0.5	1.4	2.4	0.6	1.8	1.6	-0.3	2.8	1.9	0.1	1.7	2.5	1.7	2.2	3.1	1.6	2.7
Pulse rate, automated reading	2.9	9.3	20.5	2.3	3.0	4.5	3.3	4.0	3.7	3.2	2.4	2.3	3.1	3.8	0.3	1.4	3.3	3.3	1.1	3.2	3.3
Mineral and other dietary supplements	2.9	3.8	9.4	0.1	3.1	2.9	2.0	2.1	2.9	1.8	1.7	0.9	1.6	1.6	0.3	2.7	1.7	1.7	1.6	1.8	1.9
Father’s age at death	2.8	3.7	7.9	-0.3	-2.8	-2.2	-1.7	-2.3	-1.9	-1.4	-2.3	-1.7	-1.5	-2.5	0.4	-1.7	-2.6	-2.7	-0.9	-1.4	-2.0
Tense / ‘highly strung’	2.7	4.4	8.7	-1.8	1.4	2.8	2.5	2.6	3.0	2.6	-0.4	1.3	2.7	1.4	1.6	2.3	1.5	1.7	0.7	2.6	2.4
Maternal smoking around birth	2.6	3.7	7.8	-1.0	1.5	2.7	1.6	2.4	2.8	2.4	-0.0	1.7	2.3	-0.0	2.4	1.6	1.2	2.1	1.0	2.4	2.4
Past tobacco smoking	2.6	4.9	9.2	-1.2	0.8	2.9	2.5	2.7	3.0	2.8	-0.8	1.7	2.5	1.3	1.8	2.0	1.9	2.0	2.5	2.8	2.4
Falls in the last year	2.6	3.5	6.9	-1.5	2.3	2.6	2.0	2.5	2.6	2.2	1.6	1.1	2.2	1.2	0.7	1.7	1.0	1.5	0.4	2.1	2.1
Had major operations	2.6	3.1	7.9	2.2	0.1	1.8	1.3	2.3	1.4	1.6	1.8	1.5	1.5	1.8	-1.2	-0.9	2.7	2.8	1.0	1.7	1.9
Average weekly champagne plus white wine intake	2.6	3.5	10.0	-0.8	-3.2	-1.9	-1.7	-1.4	-2.6	-2.1	-1.9	-1.7	-2.1	-0.0	-0.8	-1.6	-1.6	-1.5	-2.7	-2.1	-1.5
Diverticular disease/diverticulitis (self-reported)	2.5	3.0	7.3	0.1	2.7	1.9	2.2	1.6	1.8	1.4	2.3	2.0	1.6	0.9	0.8	2.3	1.6	1.6	0.8	1.4	2.1
Hayfever/allergic rhinitis (self-reported)	2.5	3.3	7.1	-0.3	-1.0	-1.4	-2.5	-1.3	-1.7	-1.5	-1.2	-2.7	-1.6	-1.1	-2.6	-2.0	-1.4	-2.1	-2.4	-1.5	-2.4
Heart disease (mother)	2.5	3.1	5.4	-0.2	-1.1	-1.9	-2.2	-2.0	-2.1	-2.3	-0.8	-1.6	-2.0	-0.6	-1.7	-2.0	-1.1	-1.5	-2.0	-2.3	-2.2
Depression (Nagel 2018)	2.4	3.6	6.9	-0.7	1.7	2.5	2.6	2.4	2.3	2.2	1.0	1.7	2.2	1.3	1.5	1.8	1.6	1.8	-0.2	2.2	2.2
Happiness	2.4	3.0	5.7	-1.0	2.1	2.1	1.9	1.6	2.1	2.4	2.0	1.7	2.4	0.6	1.1	1.1	1.0	1.2	0.6	2.4	1.9
Hair/balding pattern: Pattern 4	2.4	5.8	10.3	1.2	1.8	2.5	2.4	2.1	2.9	3.1	2.4	3.2	3.1	1.5	1.0	1.2	2.1	2.6	2.2	3.0	3.2
Qualifications: NVQ or HND or HNC or equivalent	2.4	2.9	5.8	-0.0	1.7	1.7	2.2	1.6	1.8	1.8	1.4	1.7	1.9	1.1	1.0	2.4	1.6	1.7	1.7	1.9	2.2
Trunk fat percentage	2.3	9.2	25.7	-1.5	2.7	2.0	4.1	1.0	3.2	2.3	1.8	4.0	3.0	0.2	4.2	5.1	1.3	3.0	3.9	2.2	4.0
Relative age voice broke	2.3	3.5	10.0	-0.5	-2.4	-1.8	-2.5	-1.7	-2.2	-1.6	-1.9	-1.6	-1.6	-1.4	-0.7	-3.2	-1.3	-1.8	-2.3	-1.6	-1.9
Diastolic blood pressure, automated reading	2.3	7.2	15.5	0.7	3.2	3.2	2.7	2.4	3.5	2.7	1.2	2.5	2.5	1.3	2.4	3.9	2.1	2.9	2.9	2.6	3.1
Age at last live birth	2.2	3.1	6.7	-0.7	-2.0	-2.1	-1.7	-2.0	-2.6	-1.8	0.4	-1.5	-1.8	-1.0	-1.8	-2.5	-0.9	-1.9	-1.5	-1.7	-2.1
Schizophrenia (2018)	2.1	4.4	8.5	0.2	1.7	2.0	2.5	2.1	2.0	1.8	0.5	2.7	1.8	1.8	2.1	2.5	2.3	2.9	2.1	1.9	2.9
Hearing difficulty/problems with background noise	2.1	3.3	6.3	0.4	0.4	2.1	2.3	2.1	1.7	1.9	0.8	2.2	2.1	2.4	1.6	1.2	1.9	2.0	1.0	2.0	2.5
Alcohol intake versus 10 years previously	2.1	3.1	9.7	0.5	1.6	1.7	2.8	0.9	2.2	1.3	1.5	1.2	1.4	1.0	0.1	2.9	1.0	1.8	3.1	1.2	2.0
Body fat percentage	2.1	8.3	25.8	-1.3	2.6	1.8	3.8	0.7	3.0	2.0	1.7	3.7	2.7	0.2	4.0	5.1	1.2	2.9	3.8	2.0	3.8
Qualifications: nursing, teaching	2.1	3.3	7.6	-0.1	-1.7	-1.4	-2.1	-0.9	-2.2	-2.4	-0.7	-1.8	-2.2	0.6	-2.8	-2.5	0.0	-1.1	-2.4	-2.3	-2.2
Eye problems/disorders: Glaucoma	2.1	2.4	6.4	1.3	0.8	1.0	1.2	1.4	1.3	2.4	1.7	2.5	2.4	1.3	0.9	-0.9	1.1	0.8	1.1	2.4	1.5
Major Depression (MDD)	2.0	2.5	5.2	0.2	1.1	1.9	1.6	1.9	1.3	1.7	1.4	2.0	1.8	2.3	0.1	-0.1	2.2	1.7	-0.0	1.7	2.0
Trunk fat mass	2.0	8.5	24.6	-2.0	3.0	1.9	3.7	0.9	3.3	2.4	1.7	3.5	3.1	-0.1	3.8	5.0	1.0	2.5	4.1	2.3	3.5
Arm fat percentage (right)	2.0	7.8	22.1	-1.6	2.6	1.5	3.7	0.6	2.8	2.2	2.2	3.5	2.8	-0.3	3.9	4.7	1.0	2.6	3.9	2.1	3.6
Serious illness, injury or assault of a close relative in last 2 years	2.0	2.3	5.3	1.3	0.9	1.3	1.2	1.8	1.5	2.1	0.4	2.1	2.2	0.6	0.4	-0.0	2.3	1.8	1.1	2.2	1.5
Arm fat mass (right)	2.0	8.2	26.4	-2.4	2.8	1.7	3.5	0.6	3.2	2.3	1.7	3.0	2.9	-0.6	4.0	5.1	0.6	2.2	4.2	2.2	3.4
Leg fat percentage (right)	2.0	7.2	27.2	-1.2	2.7	1.4	3.3	0.4	2.7	1.7	1.8	3.3	2.3	0.1	3.6	5.2	1.0	2.6	4.0	1.6	3.4
Qualifications: College or University degree	2.0	6.4	26.7	0.6	-2.8	-2.1	-3.5	-1.4	-2.9	-2.4	-1.2	-2.3	-2.4	-0.4	-3.2	-5.2	0.1	-1.5	-3.0	-2.3	-2.9
Leg fat mass (right)	2.0	7.7	28.4	-2.2	3.1	1.7	3.2	0.7	3.2	2.1	1.6	2.8	2.7	-0.2	3.5	5.3	0.7	2.1	4.2	2.0	3.2
Arm fat percentage (left)	2.0	8.1	21.3	-1.6	2.6	1.6	3.8	0.6	2.8	2.2	2.5	3.7	2.8	0.0	3.8	4.6	1.1	2.7	4.0	2.1	3.7
Mood swings	2.0	3.7	10.7	-1.8	0.8	1.6	2.2	1.6	2.0	2.4	0.3	2.5	2.5	1.1	3.3	2.1	0.7	1.1	0.9	2.4	2.4
Age started oral contraceptive pill	2.0	2.4	8.3	0.6	-2.0	-2.1	-1.3	-1.8	-2.0	-1.9	-2.9	-0.4	-1.6	-1.0	-1.1	-1.0	-0.5	-0.9	-1.2	-1.9	-1.5
Whole body fat mass	1.9	7.7	26.8	-2.2	2.7	1.6	3.5	0.5	3.0	2.1	1.4	3.1	2.8	-0.4	3.9	5.2	0.6	2.2	4.0	2.0	3.3
Leg fat percentage (left)	1.9	6.7	26.7	-1.1	2.6	1.4	3.3	0.4	2.7	1.5	1.6	3.1	2.2	-0.1	3.4	5.2	1.0	2.5	3.8	1.4	3.3
Alzheimer’s Disease (including proxy)	1.8	2.6	4.4	0.5	-1.6	-1.8	-1.5	-1.6	-1.9	-1.9	-1.0	-1.8	-2.1	-1.5	-0.8	-1.5	-1.6	-1.7	-1.4	-2.0	-2.0
Systolic blood pressure, automated reading	1.8	5.1	12.4	0.2	1.7	2.3	2.5	2.4	1.9	1.6	1.1	3.0	1.7	2.9	1.8	2.6	2.8	3.5	1.9	1.7	2.8
Pack years adult smoking proportion	1.8	2.8	7.2	0.3	1.9	2.2	2.4	1.4	1.7	1.3	2.7	1.2	1.3	1.6	0.3	2.0	0.7	1.6	2.0	1.2	1.9
Glaucoma (self-reported)	1.8	2.1	6.1	2.5	0.3	0.4	0.6	1.4	0.6	2.1	1.6	2.3	2.0	1.6	0.5	-1.2	1.1	0.7	0.7	2.1	1.1
Illnesses of siblings: Diabetes	1.8	2.2	4.0	0.9	0.6	1.7	1.5	1.3	1.7	1.7	0.2	1.7	1.8	1.9	0.7	1.2	1.4	1.9	0.7	1.7	2.0
Loneliness, isolation	1.8	2.5	4.9	-0.5	0.7	1.6	2.2	1.7	1.5	1.9	1.4	2.0	2.0	1.5	1.2	1.4	1.8	1.5	0.1	2.0	1.9
Arm fat mass (left)	1.8	7.5	24.1	-2.2	2.7	1.5	3.4	0.4	2.9	2.1	2.0	3.0	2.7	-0.5	3.6	4.9	0.6	2.2	4.2	2.0	3.2
Leg fat mass (left)	1.8	7.1	26.8	-2.1	3.0	1.6	3.2	0.6	3.1	2.0	1.4	2.6	2.5	-0.4	3.3	5.2	0.7	2.1	4.0	1.9	3.0
Systolic Blood Pressure	1.7	8.3	23.0	1.0	1.6	3.0	3.0	3.7	1.9	2.1	0.8	3.7	2.0	3.6	1.7	2.8	4.6	4.8	1.3	2.3	3.4
Hand grip strength (right)	1.7	4.7	7.3	-2.3	-2.2	-2.4	-2.3	-2.3	-2.1	-2.3	-1.8	-2.4	-2.1	-2.2	-0.6	-1.3	-2.2	-2.7	-2.0	-2.3	-2.6
Ever unenthusiastic/disinterested for a whole week	1.7	2.1	6.7	-1.1	1.7	2.1	1.2	2.6	1.9	1.3	0.8	0.6	1.2	2.0	-0.1	0.3	1.5	1.6	-0.7	1.3	1.3
Headache pain in last month	1.7	3.0	6.3	-0.1	2.0	2.5	2.0	1.6	2.5	1.8	1.8	1.6	1.7	0.7	1.4	2.1	1.3	1.6	0.7	1.7	2.1
Reason for reducing amount of alcohol drunk: Health precaution	1.7	2.0	3.6	0.4	-1.5	-1.8	-1.2	-1.5	-1.6	-1.5	-1.9	-1.2	-1.4	-1.8	0.4	-0.7	-1.7	-1.4	-1.8	-1.5	-1.1
Back pain experienced in last month	1.7	2.5	5.7	-1.0	1.7	2.3	2.4	1.4	2.3	1.5	1.3	0.6	1.4	0.2	1.1	2.2	0.0	1.1	2.4	1.5	1.5
Ever smoked	1.7	3.1	5.6	2.1	-0.9	-2.1	-2.1	-1.7	-2.4	-2.1	1.2	-1.3	-2.0	-0.7	-1.7	-2.3	-0.9	-1.0	-2.0	-2.1	-1.6
Average weekly fortified wine intake	1.6	1.8	6.0	0.5	-0.5	0.5	1.2	1.3	0.6	1.1	-0.8	2.4	1.3	2.3	0.3	-0.0	2.4	1.9	1.1	1.2	1.3
Qualifications: None of the above	1.6	3.5	11.9	0.2	2.7	1.4	2.4	1.5	2.2	1.6	0.4	1.9	1.7	0.1	1.9	3.5	0.4	1.8	2.0	1.6	2.5
Breastfed as a baby	1.6	2.0	7.6	2.2	-2.5	-1.9	-1.1	-1.2	-2.3	-1.1	0.8	0.7	-0.9	0.6	-0.6	-2.8	0.7	0.1	-0.7	-1.0	-0.5
Wheeze or whistling in the chest in last year	1.6	2.9	5.6	0.1	1.4	1.5	2.2	1.7	2.4	2.2	0.4	1.8	2.3	-0.8	1.2	1.9	1.3	1.2	1.8	2.1	2.0
Neck or shoulder pain in last month	1.6	2.2	6.0	-2.1	1.0	2.2	1.7	1.4	2.5	1.8	-0.6	0.8	1.8	0.4	1.9	1.6	-0.2	0.7	1.1	1.7	1.1
Irritability	1.6	2.7	5.6	1.1	0.6	1.5	1.7	1.6	1.7	2.4	-1.1	1.9	2.3	0.2	2.0	1.4	1.4	1.3	0.7	2.3	2.2
Risk taking	1.6	2.3	13.1	-2.1	0.8	0.2	1.1	0.4	0.8	1.2	0.6	2.6	1.5	0.1	3.6	1.3	0.8	1.3	0.2	1.2	2.2
Supplements: Zinc	1.5	1.6	5.1	-0.2	-0.5	-1.2	-1.3	-0.9	-1.6	-1.1	0.4	-1.4	-1.1	-0.2	-1.4	-2.3	-0.8	-1.3	-2.2	-1.1	-1.5
Body mass index (BMI)	1.5	6.6	26.9	-2.5	2.6	1.3	3.0	0.0	2.9	1.7	1.6	2.2	2.2	-1.2	3.8	5.2	-0.2	1.5	4.0	1.6	2.8
Worrier / anxious feelings	1.5	2.8	9.1	-0.3	-2.4	-1.4	-1.9	-1.2	-1.7	-0.9	-2.4	-0.9	-1.0	-2.0	0.3	-2.3	-1.2	-1.8	-3.0	-0.9	-1.5
Medication: Lisinopril	1.5	2.0	3.6	0.6	-1.8	-1.2	-1.3	-1.7	-1.7	-1.9	-1.3	-1.4	-1.8	-1.4	-0.5	-0.8	-1.5	-1.1	-0.4	-1.9	-1.5
Bipolar Disorder or Schizophrenia	1.4	3.3	7.3	0.5	1.6	2.1	2.2	2.0	1.9	1.6	0.7	1.8	1.4	1.7	1.5	1.8	2.1	2.7	2.0	1.6	2.4
Medication for cholesterol, blood pressure or diabetes	1.4	2.3	6.1	0.5	-1.2	-1.3	-2.0	-1.3	-0.9	-0.1	-2.3	-1.6	-0.6	-2.1	0.6	-2.0	-2.3	-2.5	-1.4	-0.2	-1.4
Medication: Amlodipine	1.4	2.0	5.6	0.1	1.7	1.8	1.6	1.6	1.3	-0.3	0.9	0.4	-0.2	2.2	-1.1	1.5	1.9	2.4	1.9	-0.2	0.5
Family relationship satisfaction	1.4	1.8	10.4	-1.3	1.9	1.8	0.4	1.4	1.5	1.6	3.2	0.4	1.5	0.7	-0.1	-0.5	0.3	0.2	0.0	1.6	0.6
Friendships satisfaction	1.4	1.8	6.3	-1.4	1.9	1.2	1.0	0.9	1.5	1.6	2.5	1.0	1.4	-0.4	0.9	0.8	0.7	0.7	1.7	1.6	1.1
Heart attack/myocardial infarction (self-reported)	1.4	1.8	6.9	0.5	2.6	1.6	1.1	1.6	1.2	0.6	2.4	0.2	0.5	2.3	-1.3	0.5	1.4	1.3	0.6	0.7	0.5
Age at First Birth	1.3	1.8	5.0	1.0	-1.6	-1.6	-1.7	-1.8	-1.9	-1.3	0.4	-1.0	-1.4	0.1	-1.7	-2.2	-0.5	-1.4	-0.5	-1.2	0.0
Schizophrenia (2014)	1.3	2.9	5.9	0.1	1.5	1.8	2.1	1.7	2.0	1.5	0.7	2.0	1.4	1.5	1.5	1.7	2.0	2.4	1.7	1.5	2.3
Frequency of depressed mood in last 2 weeks	1.3	1.8	3.5	-1.1	0.1	1.8	1.6	1.9	1.5	1.7	0.3	1.3	1.7	1.1	1.5	0.6	1.0	1.0	-1.0	1.7	1.6
Relative age of first facial hair	1.3	2.6	9.1	-1.1	-2.0	-1.8	-2.1	-0.9	-2.1	-1.1	-1.6	-1.3	-1.1	-0.3	-0.4	-3.0	-0.8	-1.8	-2.0	-1.0	-2.0
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	3.8	0.5	1.9	1.2	1.7	0.8	1.4	0.6	1.6	1.3	0.9	0.7	0.9	1.6	0.9	1.3	1.4	0.6	1.2
Exposure to tobacco smoke at home	1.3	1.5	9.0	-0.9	-0.1	0.4	1.3	-0.1	0.8	1.3	-0.6	1.2	1.3	-0.6	3.0	1.9	-0.9	0.1	1.0	1.2	1.5
Emphysema/chronic bronchitis	1.3	1.4	6.4	-0.1	2.5	0.7	0.6	0.0	1.3	1.0	1.7	0.3	0.9	-1.5	2.3	1.4	-0.5	0.1	0.5	0.9	1.2
Medication: Blood pressure	1.3	2.2	5.9	-0.4	0.4	1.2	2.0	1.6	0.8	0.9	1.6	1.9	1.2	1.8	-0.5	1.3	2.4	2.4	1.6	1.0	1.3
Long-standing illness, disability or infirmity	1.3	1.9	5.6	-1.4	2.4	2.0	1.5	1.4	2.2	0.6	2.3	0.2	0.7	1.2	-0.2	1.6	1.0	1.4	0.7	0.6	0.9
Financial situation satisfaction	1.3	1.6	3.4	-1.6	1.9	1.6	1.6	0.9	1.8	1.6	1.5	0.3	1.3	-0.3	1.2	1.2	0.3	0.6	0.6	1.5	1.2
Number of operations (self-reported)	1.3	1.9	4.9	0.6	1.1	1.6	1.5	1.7	1.6	1.6	1.1	1.1	1.5	1.0	0.6	0.2	1.7	2.2	0.9	1.6	1.7
Average weekly beer plus cider intake	1.3	1.8	5.0	-0.9	0.6	1.2	1.7	0.6	1.5	2.2	0.3	1.0	2.2	-0.4	0.6	1.7	-0.4	0.1	2.0	2.1	1.2
Heart disease (siblings)	1.3	1.6	9.3	-3.0	-0.6	-0.9	-1.1	-0.9	-1.4	-1.2	-0.6	-0.7	-1.0	-0.1	-0.6	-1.5	-0.3	-0.7	-2.3	-1.1	-1.1
Pack years of smoking	1.3	1.9	6.3	0.5	1.5	1.8	2.1	1.0	1.2	0.9	2.5	0.9	0.9	1.4	0.1	1.8	0.4	1.3	1.7	0.9	1.5
Reaction Time	1.2	2.2	5.9	-1.3	-2.4	-1.5	-1.4	-1.2	-1.3	-1.7	-1.9	-1.7	-1.9	-0.4	-0.1	-0.8	-1.4	-1.5	-1.0	-1.6	-1.7
Chronotype (morning person)	1.2	2.7	9.2	-2.1	-0.0	-2.3	0.4	-2.3	-1.4	-1.4	-0.5	-0.4	-1.3	-3.0	1.2	2.4	-1.6	-0.6	2.4	-1.6	-0.3
Hearing difficulty/problems: Yes	1.2	1.8	4.6	-0.8	0.0	1.2	1.6	1.3	0.9	1.2	2.1	1.9	1.5	1.6	1.6	0.9	1.1	1.5	0.4	1.2	1.8
Stomach or abdominal pain in last month	1.2	1.5	4.3	-0.0	1.8	2.0	1.6	1.1	2.1	1.1	0.8	0.4	1.0	0.1	0.9	1.7	0.5	0.7	1.4	1.1	1.2
Number of incorrect matches in round	1.2	2.0	4.5	-0.3	-1.4	-2.1	-1.8	-1.5	-1.7	-1.2	-1.2	-0.8	-1.1	-1.5	1.1	-0.7	-1.8	-1.9	-1.4	-1.2	-1.4
Time employed in main current job	1.2	1.4	5.7	0.7	1.4	1.0	1.4	0.5	1.3	1.0	1.0	1.2	1.2	-0.3	0.5	1.9	0.3	1.1	2.4	0.9	1.1
Ever highly irritable/argumentative for 2 days	1.2	1.4	4.9	-0.6	1.4	1.3	0.7	1.1	1.5	1.7	0.8	0.8	1.7	-0.4	2.2	0.3	-0.2	0.1	-1.0	1.6	1.5
Number of children fathered	1.2	1.4	4.4	-2.1	0.2	-0.6	-0.9	-1.2	-0.1	-1.0	-1.1	-1.4	-0.8	-1.9	1.2	0.6	-2.0	-1.2	-0.4	-1.1	-0.7
Mean time to correctly identify matches	1.2	2.3	6.0	-0.7	-2.4	-1.8	-1.6	-1.5	-1.7	-1.7	-1.4	-1.4	-1.9	-0.2	-0.2	-1.1	-1.4	-1.6	-0.6	-1.7	-2.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.5	4.9	0.1	0.0	-1.2	-1.1	-1.7	-0.5	-1.0	-1.1	-1.5	-1.0	-1.6	0.0	-0.0	-2.2	-1.8	0.5	-1.1	-1.7
Medication for cholesterol	1.2	1.8	3.8	0.8	0.8	1.4	1.1	1.0	1.7	2.0	0.8	1.4	1.9	0.3	0.4	1.1	1.5	0.9	1.6	1.9	1.5
Guilty feelings	1.2	1.8	7.0	-0.1	-2.6	-0.5	0.5	0.3	-0.3	1.3	-2.2	2.5	1.5	-0.2	1.6	-0.9	1.4	0.7	-0.1	1.4	1.1
Pain type(s) experienced in last month: Hip pain	1.2	1.5	2.8	-1.2	1.2	1.7	1.6	1.3	1.7	1.6	0.5	0.5	1.5	0.6	1.0	1.4	0.2	0.6	1.3	1.5	1.1
High cholesterol (Self-reported)	1.2	2.2	5.1	-2.0	-0.2	-0.9	-0.9	-0.9	-1.3	-2.3	-0.4	-2.2	-2.2	-0.4	-1.3	-0.2	-1.6	-1.0	-1.8	-2.2	-1.6
Medication: Paracetamol	1.2	1.8	8.2	-1.6	0.2	-0.3	-0.1	-1.1	0.6	0.6	-1.0	-0.4	0.5	-2.9	2.4	1.6	-2.3	-1.7	1.2	0.4	0.0
Intelligence (Savage-Jansen 2018)	1.1	3.3	16.8	2.2	-0.7	0.3	-1.8	1.3	-1.2	-0.1	-1.0	-0.9	-0.0	1.6	-3.5	-4.1	1.6	-0.1	-3.1	0.1	-1.3
Verbal and Numeric Reasoning (VNR)	1.1	2.7	12.4	1.2	-1.4	-0.5	-2.3	0.4	-1.4	-0.9	-1.4	-1.4	-1.0	1.1	-2.5	-3.5	0.5	-0.7	-2.6	-0.8	-1.9
Triglycerides	1.1	1.7	3.9	-1.0	0.3	1.5	0.9	1.8	1.6	1.8	0.7	1.5	2.0	0.9	0.4	0.5	1.8	1.6	0.6	1.9	0.0
Cardiovascular Disease	1.1	3.5	7.7	-1.0	0.9	1.6	2.2	2.5	1.2	1.4	0.3	2.6	1.6	2.6	1.6	2.2	2.4	2.8	0.7	1.5	2.3
Qualifications: CSEs or equivalent	1.1	1.5	5.4	-0.8	0.0	1.1	1.5	0.3	1.3	1.5	0.4	0.6	1.2	-0.7	2.3	2.3	-0.2	0.3	1.4	1.5	1.2
Had menopause	1.1	1.3	10.5	3.2	-2.0	-0.1	-0.3	-0.0	-0.2	0.3	-2.0	1.1	0.2	0.2	0.3	-1.6	0.6	0.7	0.0	0.3	0.4
Heart attack	1.1	1.5	5.9	0.5	2.4	1.3	0.7	1.4	0.9	0.2	2.3	-0.2	0.0	2.1	-1.8	0.3	1.1	1.0	0.3	0.2	0.1
Weight	1.1	5.3	19.1	-2.7	2.5	1.2	2.5	0.4	2.8	1.9	1.1	1.9	2.5	-1.1	3.0	4.4	-0.1	1.2	3.7	1.8	2.2
Peak expiratory flow (PEF)	1.1	2.7	6.9	-1.6	-0.0	-1.2	-1.9	-1.2	-1.5	-1.9	-0.8	-2.6	-1.8	-0.7	-1.5	-1.2	-1.2	-1.7	-2.3	-1.8	-2.2
Medication: Seretide 50 evohaler	1.1	1.2	6.2	1.6	-2.0	-0.3	-0.4	0.0	-0.6	0.2	-0.7	-0.4	0.1	1.3	-2.5	-2.3	0.4	-0.3	-0.7	0.2	-0.6
Prostate Cancer	1.0	1.4	7.4	2.7	-1.1	-1.0	-1.2	-0.9	-1.4	-1.4	-0.5	-0.7	-1.4	0.4	-1.5	-1.2	0.2	-0.3	-0.7	-1.3	-0.9
HDL Cholesterol	1.0	1.6	5.6	1.3	0.2	-0.6	-1.4	-0.4	-1.1	-1.8	-0.9	-2.1	-2.4	0.1	-2.0	-0.1	0.6	0.1	-0.8	-2.0	0.0
Diabetes (self-reported)	1.0	1.5	4.6	-0.9	2.1	1.6	1.4	1.9	1.6	0.7	0.6	0.9	0.9	0.8	0.2	1.0	1.5	1.7	-0.5	0.7	1.2
Medication: Ramipril	1.0	1.3	4.0	-0.4	0.7	0.6	1.6	1.2	0.4	0.4	0.6	1.4	0.7	2.0	1.0	1.7	1.5	1.7	0.3	0.5	1.4
Number of live births	1.0	1.4	3.5	-0.2	-0.8	-1.9	-1.3	-1.3	-1.5	-1.0	-1.0	-1.2	-0.8	-1.0	-0.5	-0.6	-1.8	-1.6	0.0	-1.0	-1.4
Birth weight of first child	1.0	1.8	5.4	0.2	0.8	-1.5	-1.4	-1.4	-1.0	-1.4	0.1	-1.8	-1.3	-2.0	0.1	-0.6	-2.3	-1.6	-0.9	-1.5	-1.3
Medication: Ibuprofen	1.0	1.2	2.2	-1.1	-0.6	1.1	1.1	1.3	1.1	1.4	-1.5	1.2	1.5	0.7	1.3	0.2	0.7	0.7	0.2	1.4	1.2
Medication: Allopurinol	1.0	1.3	4.2	-0.9	1.7	1.5	0.7	2.0	1.5	1.6	-0.6	0.6	1.4	0.1	0.8	0.7	0.9	0.8	-0.2	1.6	0.7
Commuting to job workplace: Car/motor vehicle	1.0	1.2	5.7	-0.2	1.3	0.8	1.1	-0.4	1.3	0.7	0.4	0.9	0.7	0.0	1.4	2.1	-0.1	0.6	2.4	0.6	1.0
Handedness (chirality/laterality): Left-handed	1.0	1.3	3.2	0.0	-0.3	-1.4	-1.0	-1.1	-1.4	-0.9	1.0	-1.2	-1.1	-1.5	-0.6	-1.8	-1.3	-1.2	-0.4	-0.9	-1.4
Lupus	0.9	1.4	5.2	2.3	-0.3	0.8	0.1	1.6	0.5	1.6	-0.5	1.1	1.3	1.5	-0.3	-1.8	1.3	0.3	-0.4	1.7	0.2
Lung FEV1/FVC ratio	0.9	4.7	8.6	-1.1	-2.3	-2.8	-2.2	-2.9	-2.9	-2.6	-1.1	-1.3	-2.5	-1.5	1.0	-0.7	-2.5	-2.6	-2.2	-2.6	-2.1
Ever had hysterectomy (womb removed)	0.9	1.1	3.3	-0.6	1.0	0.9	1.8	0.6	1.3	0.8	-0.6	1.3	1.0	0.0	1.8	1.6	0.0	0.7	0.4	0.8	1.1
Chronic bronchitis/emphysema (father)	0.9	1.1	4.8	-1.6	-1.1	-1.2	0.3	-1.3	-0.4	-0.2	-1.1	0.7	0.0	-2.2	2.0	0.6	-1.0	-0.3	-0.2	-0.2	0.4
Hair/balding pattern: Pattern 2	0.9	1.2	4.6	0.0	-1.4	-0.3	-0.6	-0.2	-0.8	-0.9	-1.8	-1.8	-1.1	-0.5	-0.9	-0.8	-0.8	-1.0	-2.1	-0.8	-1.1
Noisy workplace	0.9	1.1	4.6	-1.9	1.2	-0.4	0.4	-0.5	0.6	0.2	-0.5	0.5	0.4	-2.0	2.0	2.2	-0.6	-0.2	0.7	0.1	0.5
Qualifications: A levels/AS levels or equivalent	0.9	1.9	8.8	1.6	-0.5	0.1	-1.0	0.7	-1.1	-1.2	1.4	-0.6	-1.0	1.5	-3.0	-2.5	1.8	1.0	-1.3	-1.0	-0.7
Qualifications: O levels/GCSEs or equivalent	0.9	1.5	5.1	0.7	-1.5	-0.3	-1.4	0.0	-1.2	-1.1	0.9	-0.9	-1.2	0.7	-2.0	-2.3	0.2	-0.4	-1.9	-1.0	-1.3
Medication: Paracetamol	0.9	1.4	5.8	-1.8	0.0	0.3	0.3	-0.7	1.0	0.7	-0.3	-0.4	0.6	-2.4	2.0	1.8	-1.9	-1.2	1.2	0.5	0.3
Commuting to job workplace: Walk	0.9	1.0	5.9	-0.5	0.9	1.2	0.1	2.4	0.6	0.3	-0.3	0.2	0.1	1.3	0.3	-0.5	1.1	0.5	-2.3	0.4	0.1
Breast cancer (self-reported)	0.9	1.1	4.7	0.2	2.2	1.0	1.0	1.0	1.7	1.1	1.0	0.3	1.1	-0.5	1.2	1.3	-0.2	0.3	1.0	1.0	0.5
Osteoporosis (self-reported)	0.9	1.1	3.9	2.0	-1.3	-0.6	-1.4	-0.9	-1.1	-0.6	-0.5	-0.7	-0.8	-0.2	-1.4	-2.0	-0.5	-0.8	-0.4	-0.7	-0.9
Number of self-reported non-cancer illnesses	0.9	1.5	4.9	0.1	1.9	2.2	1.1	1.8	1.9	1.3	1.1	0.1	1.2	1.3	-1.0	0.2	0.8	0.9	-0.2	1.3	0.5
Medication: Bendroflumethiazide	0.9	1.4	2.9	0.2	1.0	1.2	1.2	1.7	1.2	1.3	1.1	1.5	1.6	1.1	-0.4	0.9	1.4	1.6	0.7	1.3	1.3
Alcohol drinker status: Never	0.9	1.1	4.8	0.5	1.3	1.0	1.1	0.4	1.4	0.4	0.9	0.5	0.5	-0.5	1.1	2.2	0.0	0.7	1.9	0.4	0.8
Breast Cancer	0.8	1.9	6.9	-1.4	-1.7	-2.6	-1.0	-2.2	-2.4	-1.3	-0.0	0.0	-1.0	-1.8	0.8	-0.3	-1.2	-0.9	-0.8	-1.3	-0.1
Diabetes (father)	0.8	0.9	2.3	0.0	0.5	0.8	0.8	1.0	0.9	1.0	1.5	0.8	1.1	0.9	-0.7	-0.2	1.5	1.3	1.2	1.0	0.9
Diabetes (mother)	0.8	1.1	2.5	1.2	-0.4	1.0	0.5	0.8	0.9	1.6	-0.2	1.1	1.6	0.9	-0.9	-0.8	1.2	1.0	0.7	1.6	1.0
Fluid intelligence score	0.8	1.7	7.6	0.9	-1.0	-0.7	-1.3	0.5	-1.4	-0.7	-1.4	-0.8	-0.8	1.1	-2.3	-2.8	0.9	-0.1	-1.9	-0.5	-1.2
Medication: Cholesterol lowering	0.8	1.3	6.4	-1.3	1.7	1.0	1.3	0.8	0.5	-0.4	2.5	0.5	-0.1	1.5	-0.3	1.3	1.3	1.4	-0.1	-0.3	0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.8	1.2	4.6	-1.2	0.9	1.5	0.4	2.2	1.1	1.0	0.2	-0.4	0.8	1.0	-1.3	-0.9	1.5	1.2	-0.7	1.0	0.4
Blood clot in the leg (DVT)	0.8	1.0	3.6	-0.4	0.7	1.1	1.5	0.8	1.1	0.9	0.4	0.6	0.8	0.3	1.9	1.5	-0.7	0.7	1.2	0.8	1.1
Exposure to tobacco smoke outside home	0.8	1.1	4.5	-1.8	0.5	0.1	1.2	-0.7	0.8	0.4	0.1	0.1	0.7	-2.0	1.0	2.1	-1.1	-0.5	1.3	0.3	0.3
Number of full sisters	0.8	1.0	4.8	-0.8	0.3	0.3	-0.5	-0.3	0.8	-0.5	-1.8	-2.2	-0.9	-1.1	0.7	1.5	-1.3	-1.0	-0.6	-0.6	-0.5
Average weekly red wine intake	0.8	1.2	5.8	0.6	-0.6	0.4	-0.5	1.0	0.1	0.7	0.3	1.2	0.9	1.5	-1.2	-1.9	2.4	1.4	-0.5	0.8	0.5
Pain experienced in last month	0.8	1.3	6.3	2.5	-0.8	-1.3	-1.2	-0.5	-1.5	-1.3	-0.2	-0.1	-1.1	0.7	-1.8	-1.5	0.8	0.3	-0.6	-1.1	-0.5
Alzheimer’s Disease (in father)	0.7	0.7	2.7	1.3	-0.1	1.2	0.5	1.6	0.6	0.3	-0.2	0.0	0.2	1.2	-1.0	-0.3	1.6	1.1	-0.5	0.4	0.3
Crohns Disease (2017)	0.7	1.5	3.4	1.2	0.4	1.2	1.8	1.1	1.8	1.6	-0.8	0.8	1.3	0.5	1.6	1.2	0.1	0.7	1.4	1.5	1.3
Crohns Disease (2012)	0.7	1.2	5.8	2.4	0.9	1.0	1.0	0.9	1.1	1.6	-0.2	0.8	1.3	0.4	0.9	0.4	0.0	0.3	1.2	1.5	0.7
Rheumatoid Arthritis	0.7	0.9	6.1	0.7	-0.3	-0.5	-0.3	0.4	-0.8	-0.5	1.0	-0.5	-0.6	1.2	-2.5	-2.0	0.9	0.2	-0.3	-0.4	-0.9
Hand grip strength (left)	0.7	1.8	3.2	-1.5	-0.7	-1.5	-1.8	-1.4	-1.2	-1.5	-0.9	-1.7	-1.3	-1.6	-0.7	-0.7	-1.2	-1.7	-0.9	-1.5	-1.8
Ever used hormone-replacement therapy (HRT)	0.7	0.9	2.2	1.3	-0.2	-1.2	-1.1	-1.2	-0.9	-1.4	-0.6	-0.5	-1.4	-0.5	-0.5	-0.4	-0.5	-0.4	-0.4	-1.5	-0.9
Fed-up feelings	0.7	1.4	3.1	-1.6	0.0	1.4	1.1	1.1	1.3	1.7	-0.2	1.4	1.7	1.0	1.3	0.7	0.9	0.5	-0.1	1.8	0.9
High blood pressure	0.7	2.0	6.2	-0.8	1.1	1.5	1.6	1.9	0.9	0.9	0.5	1.9	1.2	2.5	0.4	1.4	1.8	2.2	0.4	1.0	1.2
Waist circumference	0.7	2.5	12.3	-1.4	1.9	0.6	1.9	-0.1	1.8	0.9	0.3	1.2	1.4	-0.9	2.0	3.5	-0.2	0.8	2.8	0.8	1.3
Nervous feelings	0.7	1.4	5.0	-2.2	-1.0	-1.1	-0.7	-1.3	-1.1	-0.7	-0.4	-0.8	-0.7	-1.8	1.1	-0.1	-1.5	-1.7	-1.1	-0.7	-1.0
Neuroticism score	0.7	1.5	3.7	-1.2	-0.9	0.8	1.1	1.1	0.8	1.9	-1.3	1.4	1.9	0.8	1.6	-0.1	0.9	0.3	-0.7	1.9	1.0
Forced expiratory volume in 1-second (FEV1)	0.7	2.4	5.1	-0.3	-1.0	-1.4	-2.0	-0.9	-1.9	-1.8	-0.9	-2.0	-1.8	-0.2	-1.4	-2.0	-0.9	-1.6	-1.9	-1.7	-2.3
Pulse rate	0.7	1.2	8.2	-0.9	2.9	1.7	0.5	1.6	1.6	1.0	0.2	-0.5	0.7	0.4	0.7	0.5	0.3	0.2	-0.6	1.0	-0.1
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	3.1	-1.8	-1.3	0.7	0.8	0.9	0.6	1.1	-1.7	0.8	1.2	0.4	0.9	0.0	0.1	0.2	-0.4	1.1	0.7
Depression (self-reported)	0.7	0.9	3.7	-0.4	-1.2	0.0	-0.9	-0.2	-0.3	-0.2	-1.4	-1.2	-0.4	0.1	-1.8	-1.9	0.2	-0.4	-1.1	-0.2	-1.0
Pulse wave Arterial Stiffness index	0.7	0.8	9.2	-3.0	-1.0	-0.1	-0.0	0.3	-0.0	0.1	-1.7	-0.2	0.2	0.7	0.3	0.1	0.0	-0.5	-0.3	0.2	-0.5
Gout (self-reported)	0.7	0.9	2.3	-0.9	1.4	1.1	0.5	1.1	1.3	1.3	-0.7	0.2	1.0	-0.9	1.5	0.8	-0.6	-0.3	0.1	1.2	0.1
Comparative body size at age 10	0.7	2.0	7.4	-0.4	1.3	0.4	1.0	0.1	1.0	1.1	1.9	2.0	1.3	-0.0	2.7	2.2	0.7	1.0	1.9	1.1	1.6
Pulse wave peak to peak time	0.7	0.8	7.8	2.8	1.3	0.1	0.0	-0.3	0.2	-0.1	1.8	0.1	-0.2	-0.8	-0.3	0.0	-0.1	0.4	0.5	-0.2	0.4
Hypertension (Self-reported)	0.7	1.9	5.9	-0.6	1.0	1.4	1.5	1.9	0.8	0.8	0.6	1.8	1.1	2.4	0.4	1.3	1.8	2.2	0.3	0.9	1.3
Tinnitus: Yes, now most or all of the time	0.7	0.8	2.7	1.5	0.2	-0.3	-0.9	0.4	-0.8	-0.8	0.2	-0.9	-0.9	0.7	-0.7	-1.5	-0.3	-0.6	-1.6	-0.8	-0.9
Mean Putamen Volume	0.6	0.7	4.4	-1.4	2.1	0.8	-0.7	0.2	0.7	-0.3	0.6	-1.2	-0.6	0.9	0.3	-0.5	-0.0	-0.6	-0.7	-0.3	-0.9
Primary Biliary Cirrhosis	0.6	0.8	5.1	2.3	0.9	0.8	0.4	0.8	0.8	0.8	-0.1	1.2	0.8	0.5	0.9	-0.2	1.1	0.9	-0.1	0.8	0.7
BMI	0.6	3.6	17.3	-2.5	1.5	0.2	2.2	-0.8	1.8	1.2	0.4	1.0	1.4	-2.1	2.7	4.2	-1.1	-0.2	3.3	1.0	1.4
Smoking Status	0.6	1.3	4.3	1.8	0.3	-2.1	-0.8	-1.8	-1.5	-1.2	0.3	-0.4	-1.1	-1.5	-1.2	-0.4	-0.6	-0.7	-0.3	-1.3	-0.9
Angina	0.6	0.8	3.6	1.2	1.5	0.2	0.4	0.7	-0.2	-0.6	1.5	0.0	-0.4	1.0	-1.9	0.1	1.1	1.0	0.0	-0.5	0.2
Severe depression (siblings)	0.6	0.7	3.3	-0.2	-0.7	-0.2	-0.7	0.9	-0.6	0.0	0.2	-0.9	-0.3	0.3	-0.9	-1.8	-0.4	-0.9	-1.8	0.1	-0.9
Leg fat-free mass (left)	0.6	3.0	7.6	-2.8	2.1	1.2	1.5	0.6	2.4	1.9	1.2	0.7	2.2	-0.8	1.5	2.4	-0.3	0.2	2.8	1.8	1.1
Current tobacco smoking	0.6	1.0	3.2	1.6	1.8	0.4	1.1	0.8	0.9	1.0	1.2	0.6	0.9	0.1	-0.5	0.6	1.0	0.9	1.7	0.9	0.8
Serious illness, injury or assault to yourself	0.6	0.7	2.1	-0.4	0.9	0.6	0.4	1.0	0.5	0.2	0.7	0.9	0.1	1.4	1.3	0.4	1.1	1.2	-1.1	0.3	1.0
Leg predicted mass (left)	0.6	2.9	7.6	-2.8	2.1	1.2	1.5	0.6	2.3	1.9	1.1	0.7	2.2	-0.8	1.6	2.5	-0.3	0.2	2.8	1.8	1.0
Alcohol usually taken with meals	0.6	0.9	3.8	1.5	-1.1	-0.2	-0.8	0.3	-0.5	-0.4	-1.4	-0.4	-0.4	0.6	-1.1	-1.9	0.5	-0.3	-1.7	-0.3	-0.6
Medication: Simvastatin	0.6	0.9	2.6	-0.5	1.5	1.2	0.9	1.5	0.8	-0.2	1.4	0.2	0.0	1.6	-0.5	0.5	1.1	1.3	-0.6	-0.2	0.6
Hip circumference	0.6	2.6	9.4	-2.4	1.6	0.4	1.6	-0.5	1.7	0.9	0.6	1.1	1.4	-1.5	2.4	3.1	-0.7	0.4	3.0	0.8	1.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.8	4.2	-0.1	-0.7	-1.1	-2.0	-0.8	-1.6	-1.2	-1.0	-1.7	-1.3	-0.0	-1.4	-2.0	-0.6	-1.4	-1.5	-1.1	-2.0
Pulse wave reflection index	0.6	0.8	3.9	-2.0	-0.7	-0.0	0.5	0.5	0.2	0.4	0.6	1.4	0.7	0.9	0.3	0.3	1.2	1.2	0.9	0.5	1.0
Medication: Ventolin 100micrograms inhaler	0.6	0.8	3.9	-0.3	0.4	-0.9	-0.6	-0.9	-0.2	-0.4	0.1	-1.3	-0.4	-2.0	-1.1	-0.7	-1.0	-1.3	-0.1	-0.5	-1.0
Birth weight	0.6	1.4	2.9	-0.6	-0.9	-1.7	-1.2	-1.7	-1.4	-1.5	-0.3	-0.9	-1.1	-0.9	-0.1	-0.4	-1.5	-1.6	-0.1	-1.5	-1.3
Chronic bronchitis/emphysema (mother)	0.6	0.7	2.6	0.3	-0.1	-0.0	-0.1	0.5	0.4	1.6	-1.4	0.5	1.4	-1.1	0.9	-1.1	0.0	-0.3	-0.0	1.6	0.4
Angina (self-reported)	0.6	0.8	3.8	1.2	1.3	0.1	0.3	0.5	-0.3	-0.7	1.5	-0.0	-0.6	0.8	-1.9	0.1	1.0	0.9	0.0	-0.7	0.1
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.6	0.7	2.6	-0.5	-1.1	-0.6	-0.4	-0.1	-1.1	-0.8	0.3	-0.6	-0.7	0.8	-1.6	-1.2	-0.2	-0.3	-1.3	-0.8	-0.4
Ever had bowel cancer screening	0.6	0.7	1.9	0.9	0.1	-1.3	-0.9	-0.9	-0.9	-1.0	-0.8	-0.4	-0.8	-0.4	0.1	-1.4	-1.2	-0.7	-0.4	-1.1	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.2	2.8	0.5	-0.2	-0.8	-1.4	-0.5	-1.4	-1.5	-0.4	-1.3	-1.7	1.4	-0.5	-1.2	0.2	-0.5	-1.5	-1.4	-1.2
Hearing aid user	0.6	0.7	1.6	-0.5	0.8	0.7	1.1	1.0	0.8	0.6	1.3	1.0	0.8	1.2	0.6	0.9	0.5	0.9	-0.0	0.6	1.0
Ever had prostate specific antigen (PSA) test	0.6	0.7	6.0	0.8	-1.0	-0.8	-0.7	-0.1	-0.8	0.0	0.1	-0.0	0.2	0.3	-1.4	-2.5	0.4	-0.1	-0.2	0.1	-0.6
Vascular/heart problems diagnosed by doctor	0.6	1.8	5.7	0.6	-1.3	-1.3	-1.5	-1.7	-0.6	-0.4	-1.0	-1.6	-0.7	-2.4	0.2	-1.4	-1.9	-2.3	-0.3	-0.5	-1.1
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	2.7	-0.6	1.6	0.2	-0.3	0.0	0.3	-1.1	0.2	-1.3	-1.2	-0.1	0.1	1.3	-1.0	-0.2	-0.1	-1.2	-0.9
Supplements: Calcium	0.6	0.7	3.4	1.0	-0.4	0.4	-0.9	0.4	-0.2	-0.4	-0.6	-1.0	-0.4	0.7	-1.8	-1.3	-0.1	-0.4	-1.4	-0.4	-0.8
Neuroticism (Nagel 2018)	0.5	1.1	3.9	-1.5	-1.6	-0.7	-0.5	-0.4	-0.8	0.5	-2.0	-0.2	0.3	-0.8	0.6	-1.7	-0.5	-1.2	-1.9	0.5	-0.6
Body Mass Index (BMI) (2010)	0.5	0.8	5.1	-0.8	-0.0	0.5	0.8	0.3	0.7	0.9	1.0	0.5	0.9	0.1	-0.4	0.6	0.9	1.2	2.3	0.9	0.0
Fasting Glucose	0.5	0.5	3.4	1.8	0.6	1.0	0.1	1.1	0.7	0.7	0.8	0.0	0.4	-0.4	-0.5	-0.2	0.5	0.8	0.6	0.6	0.0
HbA1C	0.5	0.6	3.2	1.0	0.5	-0.1	-0.2	0.4	0.1	1.6	-0.6	-1.2	-0.1	0.1	-1.8	0.3	0.2	0.4	0.8	0.8	0.0
LDL Cholesterol	0.5	0.8	2.0	-0.7	0.8	1.3	1.0	1.4	1.4	0.7	0.6	0.0	0.7	0.9	-0.1	0.8	1.0	1.4	0.1	0.7	0.0
Type 2 Diabetes (T2D) (2018)	0.5	1.0	4.5	0.5	2.1	0.8	0.8	1.4	0.5	0.4	1.2	0.8	0.6	0.8	-1.2	0.1	1.5	1.1	-0.7	0.4	0.5
Lung FVC	0.5	2.5	5.4	1.7	-1.0	-1.0	-2.2	-0.6	-1.7	-1.8	-1.6	-2.3	-2.0	-0.1	-1.1	-1.4	-1.5	-1.4	-1.7	-1.8	-2.0
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	2.1	0.1	0.2	1.2	0.5	1.3	1.0	1.2	-1.0	-0.0	0.9	-0.1	0.4	-1.4	0.5	-0.1	-0.6	1.2	0.0
Tinnitus: Yes, but not now, but have in the past	0.5	0.5	3.0	-0.9	0.7	-0.5	-0.2	-0.6	-0.1	-0.1	-0.5	-0.4	-0.0	-1.7	1.2	-0.2	-1.2	-0.6	-0.5	-0.2	-0.1
Medication: Levothyroxine sodium	0.5	0.9	3.8	2.0	0.5	0.4	0.9	0.5	0.3	0.8	1.2	0.9	0.8	1.2	-0.9	-0.1	1.0	1.1	1.2	0.8	0.9
Medication: Lansoprazole	0.5	0.5	1.9	1.1	0.8	1.1	0.4	1.4	1.0	0.7	-0.3	-0.3	0.5	0.3	-0.9	-0.6	0.5	0.6	-0.0	0.7	0.6
Length of working week for main job	0.5	0.5	2.9	-0.6	1.2	-0.7	-0.7	-0.7	-0.1	0.1	0.7	-0.0	0.1	-1.7	1.1	-0.2	-0.8	-0.7	-0.1	0.0	-0.2
Hypothyroidism/myxoedema (self-reported)	0.5	0.9	2.7	1.5	0.1	0.6	1.1	0.4	0.7	1.4	0.3	1.0	1.3	0.6	0.1	0.3	0.6	0.7	1.6	1.3	1.0
Eye problems/disorders: None of the above	0.5	0.6	3.3	-1.2	0.6	0.4	-0.0	0.3	0.6	0.4	-0.9	-0.1	0.4	-0.9	1.8	1.5	-0.6	-0.1	-0.2	0.3	0.4
Medication for pain relief, constipation, heartburn	0.5	0.8	7.5	2.7	0.1	-0.2	-0.2	-0.1	-0.5	-0.1	0.9	0.5	-0.3	1.0	-1.0	-1.0	1.3	0.8	0.2	0.0	0.2
Illnesses of father: Heart disease	0.5	0.6	1.8	0.2	-0.8	0.6	1.0	1.2	-0.3	0.3	-0.3	1.2	0.4	1.3	-0.3	0.3	1.3	0.9	-0.4	0.4	1.1
Leg fat-free mass (right)	0.5	2.4	6.3	-2.5	1.9	1.2	1.3	0.6	2.3	1.8	1.0	0.5	2.1	-0.9	1.2	2.0	-0.3	0.0	2.5	1.7	0.8
Illnesses of father: None of the above (group 1)	0.5	0.6	3.0	0.5	0.5	-0.5	-0.6	-1.4	-0.0	-0.2	0.0	-0.7	-0.3	-0.7	0.8	-0.5	-1.7	-1.1	0.1	-0.3	-0.7
Smoking status: Current	0.5	0.8	3.2	1.8	1.4	0.2	0.8	0.6	0.7	0.8	1.2	0.7	0.7	-0.0	-0.4	0.4	0.8	0.8	1.5	0.7	0.7
Leg predicted mass (right)	0.5	2.5	6.6	-2.5	2.0	1.3	1.4	0.7	2.3	1.8	1.0	0.6	2.1	-0.8	1.3	2.1	-0.2	0.1	2.6	1.8	0.9
Ever taken oral contraceptive pill	0.5	0.6	2.7	-0.1	-0.9	-0.8	-0.2	-0.6	-0.6	-0.1	1.0	-0.6	-0.2	-1.6	-0.4	-0.8	-0.8	-1.2	0.4	-0.1	-1.1
Basal metabolic rate	0.5	2.6	8.0	-2.6	1.9	1.0	1.3	0.5	2.2	1.6	0.8	0.5	1.9	-0.8	1.4	2.7	-0.4	0.1	2.8	1.5	0.9
Fractured/broken bones in last 5 years	0.5	0.7	4.8	2.2	0.1	-0.1	0.6	0.6	-0.4	0.5	0.9	0.0	0.4	1.0	-1.7	-0.5	0.3	0.5	-0.0	0.5	0.6
Myopia	0.5	0.8	3.1	1.8	0.9	1.1	-0.0	1.0	1.2	0.8	0.8	0.3	0.8	0.1	-0.4	-0.1	0.9	0.7	1.2	0.8	0.4
Arm predicted mass (left)	0.5	2.4	8.0	-2.3	2.0	0.9	1.1	0.5	2.0	1.5	0.4	0.4	1.8	-0.8	1.4	2.8	-0.3	0.2	2.8	1.4	0.9
Type 2 Diabetes (T2D) (2012)	0.4	0.4	1.4	0.5	-0.9	0.2	0.0	0.2	0.2	0.3	-0.9	-0.4	0.3	0.9	-0.8	-0.5	1.1	0.9	1.2	0.5	0.0
Ulcerative Colitis	0.4	0.5	1.1	0.9	0.9	0.3	0.7	0.0	0.7	1.1	1.1	0.9	0.9	0.6	0.7	0.3	0.5	0.3	0.6	1.0	0.7
Blood Eosinophil Count	0.4	2.9	10.0	-0.0	-0.5	-2.4	-1.6	-2.5	-1.1	-0.5	-2.6	-0.7	-0.7	-3.2	2.8	1.3	-2.3	-1.6	0.5	-0.7	-0.2
Blood Platelet Count	0.4	5.0	15.3	2.5	2.2	1.7	3.3	0.9	2.5	1.4	0.5	1.0	1.0	1.8	-0.1	3.7	2.4	2.8	3.9	1.3	2.5
Blood White Count	0.4	2.8	8.5	0.7	1.9	2.4	1.4	2.1	2.0	1.3	0.4	0.6	1.1	2.4	-0.9	0.2	2.9	2.6	0.7	1.4	1.5
Respiratory disease	0.4	0.9	3.0	-0.5	1.7	1.2	0.9	1.1	1.7	1.4	0.3	0.2	1.3	-0.3	0.5	0.7	0.5	0.2	0.2	1.4	0.6
Sensitivity / hurt feelings	0.4	0.7	4.6	-2.1	0.3	-0.4	-0.1	-0.6	-0.2	-0.1	0.5	-0.6	-0.1	-0.7	1.4	-0.0	-1.3	-1.3	-0.7	-0.2	-0.5
Eye problems/disorders: Diabetes related eye disease	0.4	0.5	1.7	-0.4	0.8	1.3	0.5	0.8	1.2	0.1	1.0	-0.5	0.1	0.6	-0.6	0.8	0.5	0.9	0.2	0.1	0.4
High blood pressure (mother)	0.4	0.6	4.1	0.5	-0.5	0.3	-0.2	0.6	-0.5	-1.0	-0.3	-0.9	-0.8	1.0	-0.4	0.8	-0.0	-0.2	-2.0	-1.0	-0.5
Had other major operations	0.4	0.5	1.5	-0.0	1.2	0.4	0.9	0.4	0.8	0.4	0.5	0.5	0.7	0.2	0.6	1.0	0.4	1.0	0.9	0.4	0.8
Forced vital capacity (FVC)	0.4	1.7	4.8	0.3	-0.7	-0.9	-1.8	-0.2	-1.4	-1.2	-0.8	-1.8	-1.1	-0.1	-2.0	-2.2	-0.6	-1.3	-1.2	-1.1	-2.1
Financial difficulties in last 2 years	0.4	0.5	1.3	0.4	0.1	0.8	0.7	0.6	0.5	1.1	0.8	0.7	1.0	0.8	0.2	-0.2	0.6	0.4	0.5	1.2	0.8
Mouth/teeth dental problems: Dentures	0.4	0.7	1.8	-1.0	-0.2	-1.0	0.5	-1.3	-0.8	-1.0	-0.3	-0.3	-0.9	-0.8	0.4	0.9	-0.9	-0.6	1.3	-1.1	-0.6
Loud music exposure frequency	0.4	0.4	2.0	-0.4	0.6	-0.6	0.1	-0.0	-0.1	0.2	0.6	0.9	0.5	-1.1	1.4	0.5	0.6	0.3	-0.7	0.2	0.8
Medication: Omeprazole	0.4	0.5	2.8	-0.7	1.7	0.5	-0.0	0.4	0.9	-0.3	-0.1	-0.7	-0.4	-0.1	0.9	1.4	-0.8	-0.1	-0.1	-0.4	-0.4
Suffer from ‘nerves’	0.4	0.6	1.6	-1.2	0.2	0.7	-0.6	0.9	0.4	0.3	-0.9	-1.1	0.1	-0.1	-0.6	-1.1	-0.1	-1.0	-1.3	0.4	-1.0
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	2.8	-0.7	0.9	1.1	0.4	1.7	1.1	1.5	0.4	0.3	1.4	0.9	-0.4	-0.5	0.7	0.2	-0.8	1.5	0.4
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.4	1.7	0.5	-0.4	-0.7	1.1	-1.1	-0.4	0.1	-0.2	0.6	0.3	-0.6	0.7	0.9	-0.3	-0.0	1.3	0.1	0.5
Osteoarthritis (self-reported)	0.4	0.5	1.8	-0.8	0.9	1.2	0.4	1.3	0.6	0.8	0.5	-0.0	0.4	1.2	-0.1	-0.3	0.4	0.4	-0.7	0.8	0.6
Commuting to job workplace: Public transport	0.4	0.5	1.6	0.7	-1.1	0.0	-0.6	0.0	-0.6	-0.7	0.6	-0.1	-0.6	-0.3	-0.8	-1.3	0.7	0.7	-0.9	-0.6	0.0
Illnesses of father: High blood pressure	0.4	0.5	2.7	0.4	-0.4	0.2	-0.5	0.7	-0.4	-0.5	-0.1	-1.2	-0.8	0.9	-1.6	-0.6	0.6	0.2	-0.4	-0.4	-0.7
Arm fat-free mass (left)	0.4	2.1	7.8	-2.5	1.8	0.8	1.1	0.5	1.9	1.3	0.2	0.4	1.6	-0.7	1.1	2.8	-0.3	0.2	2.5	1.2	0.8
Basal cell carcinoma (self-reported)	0.4	0.5	3.1	-1.8	-1.0	-0.5	0.0	-0.4	-0.7	-0.9	0.3	-0.5	-0.7	-0.1	1.2	0.4	-0.4	-0.1	-0.7	-0.8	-0.1
Deep venous thrombosis (DVT) (self-reported)	0.4	0.6	1.9	-0.2	0.6	0.9	1.2	0.6	0.8	0.6	0.5	0.3	0.5	0.5	1.4	1.0	-0.9	0.4	0.7	0.6	0.8
Depressed Affect (Nagel 2018)	0.3	0.6	1.8	-1.4	-0.9	0.1	0.7	0.2	0.1	1.2	-0.6	0.7	1.2	-0.1	0.9	-0.7	-0.0	-0.5	-1.0	1.2	0.2
Schizophrenia vs Biploar Disorder	0.3	0.3	1.2	-0.2	-0.1	-0.1	-0.7	-0.5	0.3	-0.6	-0.4	-1.1	-0.8	-1.1	0.4	0.5	-0.6	-0.6	-0.1	-0.6	-0.6
Worry (Nagel 2018)	0.3	0.5	2.4	-0.6	-0.8	0.2	-0.5	0.2	-0.2	0.6	-1.4	-0.2	0.4	-0.2	0.0	-1.6	-0.2	-0.6	-1.5	0.6	-0.3
Neuroticism (2016)	0.3	0.5	2.7	-1.4	-0.1	0.3	-0.3	0.7	0.1	0.4	0.2	0.1	0.4	0.7	-0.5	-1.4	0.2	-0.5	-1.6	0.4	-0.2
Allergy or Eczema	0.3	0.7	2.0	-1.4	1.4	-0.1	-0.6	0.2	-0.1	-0.2	0.7	-1.4	-0.3	0.6	-0.7	-1.0	-0.3	-0.8	-1.2	-0.2	-0.9
Neuroticism	0.3	0.7	2.1	-0.2	-0.9	0.3	0.9	0.6	0.2	1.4	-1.0	1.0	1.4	0.4	0.7	-0.8	0.4	0.0	-0.7	1.4	0.6
Average weekly spirits intake	0.3	0.4	3.0	1.7	-0.1	-0.1	-0.3	0.1	0.1	0.3	0.0	0.7	0.0	-0.0	0.7	-1.3	0.7	0.6	-0.4	0.2	0.7
Medication for hormone replacement therapy	0.3	0.4	1.6	-0.1	0.6	-0.4	-0.1	-0.3	-0.4	-0.7	0.3	-0.9	-0.7	-1.3	0.2	0.5	-0.8	-0.5	0.3	-0.7	-0.5
Taking other prescription medications	0.3	0.4	1.5	0.6	0.7	1.1	0.8	1.1	1.2	0.5	-0.2	-0.1	0.4	1.0	-0.6	0.2	0.5	0.6	0.0	0.4	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.3	0.7	3.2	-0.6	-0.7	-0.9	-0.6	-1.3	-0.4	-0.3	-0.3	0.2	-0.3	-1.6	1.8	0.8	-0.8	-0.2	0.5	-0.3	0.5
Sitting height	0.3	2.4	6.3	-1.2	2.5	1.8	1.0	1.9	2.3	2.0	1.3	0.2	2.2	0.7	-0.7	1.3	0.6	0.8	2.1	2.0	0.7
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.7	2.3	-0.4	1.1	0.3	0.5	0.1	0.7	0.7	1.1	0.7	0.7	-0.0	1.0	0.9	0.6	1.0	1.5	0.7	1.3
Mouth/teeth dental problems	0.3	0.5	1.7	0.6	0.6	0.7	-0.4	1.1	0.6	0.5	0.6	-0.5	0.2	1.3	-1.1	-1.0	0.8	0.5	-0.7	0.6	-0.2
Impedance of arm (left)	0.3	1.3	5.1	2.2	-1.7	0.0	0.4	0.3	-1.0	-0.2	0.2	1.7	0.0	1.2	-0.1	-1.9	1.4	1.3	-1.4	-0.0	0.7
Arm fat-free mass (right)	0.3	1.5	5.1	-2.3	1.8	0.7	0.8	0.5	1.6	1.1	0.5	0.1	1.4	-0.5	0.7	2.2	-0.3	-0.1	2.2	1.0	0.5
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.5	-0.2	0.8	0.6	0.1	1.1	0.4	0.0	0.5	-0.8	-0.2	0.2	-1.2	-0.8	0.5	-0.1	-1.0	0.1	-0.5
Arm predicted mass (right)	0.3	1.4	5.1	-2.2	1.7	0.6	0.6	0.3	1.6	1.0	0.2	-0.1	1.2	-0.6	0.6	2.2	-0.6	-0.2	2.2	0.9	0.3
Knee pain experienced in last month	0.3	0.5	2.3	-1.5	-0.5	0.1	0.2	0.0	0.5	0.1	-1.2	-0.2	-0.1	-0.7	1.5	0.8	-0.8	-0.1	0.0	-0.0	0.5
Whole body fat-free mass	0.3	1.5	6.0	-2.5	1.5	0.6	0.6	0.2	1.6	1.2	0.5	-0.1	1.5	-0.8	0.8	1.8	-0.7	-0.4	2.3	1.1	0.2
Diabetes diagnosed by doctor	0.3	0.6	3.9	-0.7	2.0	1.0	0.5	1.1	0.8	-0.1	0.3	0.1	0.1	0.5	-0.3	0.4	0.8	1.0	-0.7	-0.1	0.3
Eye problems/disorders: Cataract	0.3	0.4	1.0	0.4	-1.0	0.5	0.4	0.6	-0.0	-0.1	-1.0	0.2	-0.3	0.8	-0.7	-0.8	1.0	0.9	0.5	-0.0	-0.0
Asthma (self-reported)	0.3	0.7	1.9	-1.4	0.8	0.3	0.9	0.5	1.1	1.1	-0.4	0.5	1.1	-1.1	1.0	0.6	-0.1	-0.3	0.4	1.1	0.4
Whole body water mass	0.3	1.6	6.0	-2.4	1.6	0.6	0.6	0.3	1.6	1.3	0.6	-0.1	1.5	-0.8	0.7	1.8	-0.6	-0.3	2.3	1.2	0.3
Miserableness	0.3	0.6	1.4	-0.5	-0.5	0.8	0.9	0.9	0.4	0.7	-0.3	1.2	0.8	1.1	0.9	0.1	0.9	0.4	-0.9	0.7	0.6
Ever depressed for a whole week	0.3	0.4	4.6	0.2	0.3	-0.1	0.3	0.5	-0.3	0.2	2.1	0.4	0.4	0.9	-0.7	-0.2	0.2	0.2	-0.0	0.3	0.3
Impedance of whole body	0.3	1.3	6.0	2.4	-1.5	0.2	0.4	0.6	-0.8	-0.2	-0.5	1.6	-0.0	1.5	-0.4	-1.5	1.6	1.4	-1.5	-0.1	0.8
Bipolar Disorder (2018)	0.2	0.2	0.8	0.6	0.5	0.9	0.4	0.6	0.5	0.3	0.5	-0.4	-0.1	0.7	-0.3	-0.3	0.5	0.7	0.6	0.2	0.2
Coronary Artery Disease (CAD)	0.2	0.3	1.2	-1.1	-0.7	0.1	-0.1	-0.0	-0.4	0.1	0.2	0.7	0.4	0.8	-0.7	-0.8	0.8	0.1	-0.2	0.2	0.0
Heel T-Score	0.2	1.2	6.1	-0.7	-0.5	-1.4	-1.0	-1.3	-1.1	-1.2	-0.7	-0.4	-1.5	-1.0	2.5	0.2	-1.1	-0.5	0.5	-1.2	-0.5
Waist Hip Ratio (WHR)	0.2	0.9	3.4	1.5	0.1	0.7	1.0	1.1	0.5	0.4	-0.2	1.1	0.7	1.4	-0.9	0.3	1.9	1.4	-0.3	0.5	0.6
Hypothyroidism (self reported)	0.2	0.5	2.6	1.6	-0.1	0.3	0.6	0.0	0.5	1.2	-0.0	0.5	1.0	0.1	-0.3	0.1	0.2	-0.1	1.1	1.1	0.4
Hair Pigment	0.2	4.6	15.2	-1.0	-2.4	-1.2	-2.5	-0.4	-2.1	-1.9	-2.6	-2.2	-2.0	0.3	-2.9	-3.1	-0.3	-1.6	-3.9	-1.7	-2.5
Number of treatments/medications taken	0.2	0.4	3.7	-0.1	-0.3	0.1	-0.1	0.6	-0.1	-0.2	-0.2	-0.3	-0.0	0.8	-1.9	-1.1	0.6	0.2	-0.4	-0.2	-0.6
Impedance of leg (right)	0.2	0.8	5.5	2.3	-0.8	-0.1	-0.0	0.4	-0.8	-0.6	-0.9	0.9	-0.5	1.3	-0.2	-0.3	1.2	1.1	-1.0	-0.5	0.5
Hayfever, allergic rhinitis or eczema	0.2	0.4	1.4	-1.1	1.1	0.1	-0.5	0.7	0.0	-0.2	0.6	-1.1	-0.3	0.7	-0.6	-0.7	0.2	-0.2	-1.2	-0.2	-0.5
Impedance of leg (left)	0.2	1.2	7.8	2.8	-1.1	0.0	0.1	0.6	-0.8	-0.7	-1.3	0.9	-0.7	1.3	-0.5	-0.4	1.5	1.3	-1.2	-0.6	0.5
Illnesses of siblings	0.2	0.3	1.8	0.7	1.4	0.1	0.2	0.2	0.3	0.6	0.6	-0.5	0.4	-0.6	-0.1	0.5	-0.3	-0.2	0.9	0.6	0.1
Impedance of arm (right)	0.2	1.0	4.6	2.1	-1.1	0.3	0.4	0.5	-0.5	0.2	0.1	1.5	0.3	0.7	0.0	-1.7	1.4	1.2	-1.2	0.3	0.8
Trunk fat-free mass	0.2	1.0	5.1	-2.3	1.2	0.1	-0.1	-0.1	1.1	0.8	0.2	-0.7	0.9	-0.9	0.3	1.3	-1.0	-0.9	1.8	0.7	-0.4
Hair/balding pattern: Pattern 3	0.2	0.3	1.0	-0.2	1.0	0.3	0.0	0.6	0.3	0.3	0.9	0.3	0.2	0.4	0.6	0.5	0.6	0.7	0.7	0.3	0.3
Asthma	0.2	0.5	2.0	-1.4	0.6	-0.0	0.6	0.1	0.8	0.7	-0.4	0.4	0.8	-1.3	0.8	0.6	-0.2	-0.5	0.4	0.7	0.1
Prospective memory result	0.2	0.2	1.0	-0.3	-0.7	-0.8	0.0	-0.7	-0.7	-0.0	0.5	0.2	0.1	-0.4	-0.3	0.4	-0.4	-0.5	1.0	-0.0	-0.2
Lung cancer (father)	0.2	0.3	0.8	-0.7	0.2	-0.1	-0.4	-0.7	0.1	0.4	0.7	0.6	0.6	-0.4	0.6	-0.9	-0.9	-0.6	0.1	0.4	-0.2
Illnesses of mother	0.2	0.2	0.9	-0.8	0.9	0.4	0.0	0.3	0.5	-0.2	0.4	-0.5	-0.6	-0.5	0.4	0.7	-0.3	0.0	0.1	-0.2	0.2
Trunk predicted mass	0.2	1.0	5.4	-2.3	1.1	0.0	-0.1	-0.1	0.9	0.7	0.1	-0.7	0.9	-0.9	0.2	1.2	-1.0	-0.9	1.7	0.6	-0.5
High blood pressure (siblings)	0.2	0.3	1.4	-0.2	-1.2	-0.0	0.3	0.1	-0.2	-0.6	-1.0	0.4	-0.3	0.8	0.3	0.8	0.0	0.6	-0.2	-0.6	0.2
Forced vital capacity (FVC), Best measure	0.2	0.9	3.0	0.2	-0.2	-0.5	-1.5	-0.1	-0.7	-0.3	-1.0	-1.5	-0.3	-0.0	-1.5	-1.7	-0.4	-1.2	-0.6	-0.2	-1.6
Mouth/teeth dental problems: Loose teeth	0.2	0.2	1.4	0.3	-1.2	-0.7	0.1	-0.3	-0.8	-0.3	0.6	0.1	-0.2	0.2	0.2	-0.1	-0.3	-0.0	-0.2	-0.3	0.3
Medication: Aspirin	0.2	0.3	1.1	-1.1	-0.1	-0.2	0.5	0.4	-0.6	-0.4	1.1	0.7	-0.0	0.6	0.2	-0.2	0.7	0.6	-0.4	-0.3	0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.2	0.3	1.0	-0.3	-0.3	-0.2	0.3	-0.3	-0.2	-0.0	-0.7	-0.2	0.1	-0.4	1.0	1.0	-0.6	-0.2	-1.0	-0.1	0.6
Medication: Aspirin	0.2	0.3	0.9	-1.0	-0.1	0.0	0.7	0.4	-0.4	-0.2	0.8	0.7	0.0	0.8	0.0	-0.2	0.8	0.6	-0.2	-0.2	0.3
Medication: Gliclazide	0.2	0.2	0.7	0.6	0.3	0.2	0.4	-0.1	-0.0	-0.6	0.5	0.4	-0.2	0.6	-0.0	0.8	0.7	0.5	-0.5	-0.5	0.4
Medication: Blood pressure	0.2	0.4	2.9	1.0	0.1	0.0	0.0	0.5	-0.7	-0.5	-0.2	0.6	-0.4	1.7	-0.5	-0.6	0.5	0.9	-0.7	-0.4	-0.0
Commuting to job workplace: Cycle	0.2	0.2	0.8	-0.3	-0.4	-0.2	-0.3	0.9	0.4	0.2	-0.9	-0.4	0.1	-0.9	0.0	-0.5	0.1	0.1	-0.2	0.1	-0.1
Irritable Bowel Disease (IBD)	0.1	0.3	1.5	0.6	0.4	0.1	0.7	0.1	0.8	0.7	-0.6	0.1	0.4	-0.3	1.2	0.7	-0.5	-0.3	0.6	0.6	0.3
Ulcerative Colitis (UC)	0.1	0.1	0.8	0.2	0.0	-0.5	0.1	-0.5	-0.0	0.1	-0.1	0.0	-0.1	-0.7	0.9	0.3	-0.3	-0.5	-0.0	0.0	-0.0
Blood Red Count	0.1	1.1	3.1	-0.7	1.1	-0.3	-0.7	-1.3	0.4	-1.0	-1.1	-1.7	-1.2	-1.5	-0.2	1.8	-1.1	-0.6	0.1	-1.1	-0.8
Height	0.1	1.0	8.5	-1.7	0.2	0.0	-0.1	-0.2	0.3	0.1	0.4	-0.2	0.9	0.8	-2.9	-1.0	-0.2	-0.5	1.3	0.2	-1.2
Tanning	0.1	1.2	6.0	-0.6	2.4	1.0	0.8	0.3	1.5	1.0	0.1	-0.7	0.6	-0.8	0.8	1.5	-1.5	-0.4	1.6	0.8	0.4
Medication: Metformin	0.1	0.2	0.6	-0.6	0.0	0.1	0.6	0.3	-0.2	-0.5	-0.8	-0.2	-0.3	0.5	0.0	0.6	0.1	0.4	-0.8	-0.5	0.0
Allergy	0.1	0.3	2.2	0.8	-1.5	-0.5	-0.0	-0.7	-0.7	-0.3	-0.0	0.6	-0.2	0.3	-0.2	-0.1	0.2	0.2	0.6	-0.3	0.1
Mouth/teeth dental problems: Bleeding gums	0.1	0.1	0.6	-0.4	-0.1	0.2	0.1	0.2	-0.2	0.0	0.6	0.6	0.1	-0.0	0.8	0.5	0.1	0.3	-0.5	0.0	0.4
Migraine (self-reported)	0.1	0.2	0.7	-0.8	0.1	0.7	0.5	-0.2	0.5	0.1	0.4	-0.4	-0.1	0.7	0.3	0.7	-0.3	-0.1	0.1	0.1	0.2
Comparative height size at age 10	0.1	0.5	2.6	-0.6	1.6	0.5	0.7	0.4	0.2	-0.1	0.9	-0.0	0.2	1.1	-0.1	1.2	0.1	0.5	0.8	-0.1	-0.1
Mouth/teeth dental problems: Mouth ulcers	0.1	0.2	0.5	0.3	0.7	-0.3	0.0	-0.6	0.0	0.0	-0.5	0.7	0.4	-0.2	0.7	0.7	-0.2	-0.5	-0.3	0.0	0.4
Standing height	0.0	0.4	1.1	-0.5	0.4	0.1	-0.6	0.6	0.4	0.6	-0.6	-0.2	1.0	0.1	-1.1	-0.9	0.1	-0.5	0.2	0.7	-0.8

Hub : Genes

RNF4

Models

Trait associations