[Hub]/) : Traits : Whole body fat-free mass : →

chr1:752,566-3,191,909

Best TWAS P=1.38e-11 · Best GWAS P=5.23e-10 conditioned to 2.4e-13

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	GTEx	Brain Cerebellar Hemisphere	RP5-890O3.9	0.24	0.02	lasso	9	0.02	1.3e-01	-6.21	6.8	1.4e-11	-0.91	0.02	0.67	TRUE
23	METSIM	Adipose	TNFRSF14	0.07	0.05	blup	373	0.05	1.9e-07	3.95	6.6	4.7e-11	-0.08	0.98	0.01	TRUE
11	GTEx	Esophagus Muscularis	RP11-181G12.2	0.23	0.14	lasso	4	0.19	1.0e-11	5.12	6.0	1.5e-09	-0.06	0.41	0.58	TRUE
6	GTEx	Adipose Visceral Omentum	RP11-345P4.6	0.40	0.24	enet	28	0.20	1.8e-10	2.33	5.4	6.4e-08	-0.13	1.00	0.00	TRUE
5	GTEx	Adipose Visceral Omentum	RP1-283E3.4	0.26	0.05	enet	25	0.16	1.5e-08	-2.68	-5.3	1.1e-07	0.21	0.14	0.12	TRUE
3	GTEx	Adipose Subcutaneous	C1orf86	0.15	0.05	enet	10	0.04	2.0e-04	-5.26	-6.6	4.4e-11	0.37	0.34	0.23	FALSE
14	GTEx	Muscle Skeletal	NADK	0.06	0.00	enet	9	0.00	1.3e-01	-5.61	-6.0	1.5e-09	0.79	0.06	0.79	FALSE
9	GTEx	Esophagus Gastroesophageal Junction	RP11-181G12.2	0.16	0.02	enet	18	0.01	1.1e-01	5.77	5.9	3.5e-09	-0.06	0.07	0.37	FALSE
13	GTEx	Lung	AL590822.2	0.09	0.00	lasso	3	0.00	2.0e-01	5.46	5.9	4.3e-09	-0.05	0.07	0.26	FALSE
21	GTEx	Skin Sun Exposed Lower leg	TMEM52	0.17	0.14	lasso	7	0.15	2.0e-12	5.79	5.8	5.0e-09	-0.92	0.06	0.94	FALSE
2	CommonMind	Brain Pre-frontal Cortex	SLC35E2	0.35	0.15	enet	24	0.17	1.0e-20	-6.19	5.8	5.6e-09	-0.71	0.01	0.99	FALSE
12	GTEx	Lung	NADK	0.07	0.03	lasso	3	0.02	8.5e-03	5.25	-5.8	6.5e-09	0.94	0.04	0.88	FALSE
26	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	TMEM52	0.02	0.01	blup	37	0.02	6.6e-03	-5.43	5.8	6.6e-09	-0.91	0.01	0.77	FALSE
7	GTEx	Brain Cerebellar Hemisphere	NADK	0.18	0.11	lasso	7	0.09	3.1e-03	-5.61	-5.8	8.4e-09	0.85	0.03	0.61	FALSE
16	GTEx	Muscle Skeletal	TMEM52	0.11	0.08	lasso	6	0.10	7.2e-10	-5.75	5.7	9.5e-09	-0.84	0.18	0.82	FALSE
24	ROSMAP	Brain Pre-frontal Cortex	C1orf222	0.11	0.14	enet	18	0.14	1.8e-17	-4.03	5.7	1.1e-08	-0.70	0.99	0.01	FALSE
1	CommonMind	Brain Pre-frontal Cortex	RER1	0.06	0.00	blup	359	0.01	8.1e-03	1.34	-5.6	2.1e-08	0.30	0.04	0.15	FALSE
20	GTEx	Skin Not Sun Exposed Suprapubic	TMEM52	0.19	0.18	lasso	4	0.14	2.6e-08	5.25	5.6	2.1e-08	-0.92	0.05	0.95	FALSE
18	GTEx	Nerve Tibial	RP11-181G12.2	0.24	0.22	lasso	5	0.21	3.7e-15	-5.26	5.5	3.1e-08	-0.04	0.67	0.33	FALSE
17	GTEx	Muscle Skeletal	RP11-181G12.2	0.12	0.13	enet	8	0.14	7.6e-14	-5.26	5.5	4.1e-08	-0.03	0.67	0.33	FALSE
27	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	C1orf86	0.03	0.02	blup	49	0.01	1.3e-02	5.79	5.4	5.2e-08	-0.05	0.02	0.80	FALSE
15	GTEx	Muscle Skeletal	C1orf86	0.20	0.16	lasso	4	0.15	8.0e-15	-5.26	-5.4	6.3e-08	0.03	0.67	0.33	FALSE
10	GTEx	Esophagus Mucosa	TMEM52	0.17	0.18	lasso	2	0.20	2.9e-13	-5.40	5.4	7.1e-08	-0.83	0.55	0.45	FALSE
4	GTEx	Adipose Subcutaneous	RP11-181G12.2	0.09	0.07	lasso	1	0.05	1.3e-04	-5.26	5.3	1.4e-07	-0.03	0.53	0.30	FALSE
25	ROSMAP	Brain Pre-frontal Cortex	MMP23B	0.05	0.04	lasso	2	0.03	1.9e-04	-5.20	-5.2	2.2e-07	0.80	0.07	0.91	FALSE
19	GTEx	Pancreas	TMEM52	0.19	0.00	enet	30	0.00	2.6e-01	-0.93	-5.2	2.5e-07	0.59	0.03	0.63	FALSE
28	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	SLC35E2	0.03	0.00	blup	34	0.01	5.3e-02	-5.53	5.1	2.9e-07	-0.82	0.02	0.51	FALSE
22	GTEx	Thyroid	PRKCZ	0.16	0.03	lasso	4	0.08	1.9e-06	-4.95	-5.1	3.1e-07	-0.03	0.27	0.06	FALSE