[Hub]/) : Traits : Whole body fat-free mass : ← →

chr5:175,662,866-177,591,495

Best TWAS P=4.48e-14 · Best GWAS P=5.12e-15 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	RAB24	0.14	0.06	enet	14	0.09	4.2e-11	4.9	5.8	5.9e-09	0.18	1.00	0.00	TRUE
2	GTEx	Adipose Subcutaneous	RAB24	0.17	0.08	enet	26	0.14	1.7e-11	4.8	6.2	7.4e-10	0.44	0.99	0.01	FALSE
3	GTEx	Adipose Subcutaneous	MXD3	0.16	0.05	enet	13	0.06	1.7e-05	6.6	6.6	3.6e-11	0.77	0.02	0.98	FALSE
4	GTEx	Adipose Visceral Omentum	MXD3	0.33	0.06	lasso	6	0.05	9.1e-04	6.6	5.9	3.7e-09	0.84	0.04	0.88	TRUE
5	GTEx	Artery Aorta	MXD3	0.36	0.22	enet	45	0.29	2.4e-16	6.6	5.3	9.4e-08	0.72	0.03	0.97	FALSE
6	GTEx	Artery Tibial	RAB24	0.18	0.09	lasso	3	0.07	2.3e-06	4.8	6.3	2.2e-10	0.49	0.99	0.00	TRUE
7	GTEx	Artery Tibial	MXD3	0.12	0.13	enet	5	0.12	7.0e-10	6.6	6.8	9.1e-12	0.89	0.18	0.82	FALSE
8	GTEx	Brain Cerebellum	MXD3	0.28	0.31	lasso	2	0.30	1.6e-09	6.6	6.6	5.2e-11	0.87	0.09	0.90	FALSE
9	GTEx	Brain Cortex	MXD3	0.47	0.20	lasso	10	0.22	7.7e-07	6.6	5.7	1.4e-08	0.78	0.06	0.59	FALSE
10	GTEx	Brain Nucleus accumbens basal ganglia	MXD3	0.24	0.14	enet	10	0.25	2.9e-07	6.6	6.6	5.4e-11	0.83	0.05	0.82	FALSE
11	GTEx	Breast Mammary Tissue	MXD3	0.26	0.08	lasso	5	0.10	1.3e-05	6.6	6.9	4.5e-12	0.86	0.00	1.00	FALSE
12	GTEx	Breast Mammary Tissue (Female)	MXD3	0.23	0.08	lasso	3	0.09	1.1e-03	7.8	6.7	2.5e-11	0.82	0.01	0.92	FALSE
13	GTEx	Colon Sigmoid	MXD3	0.35	0.27	lasso	9	0.29	6.3e-11	6.6	6.7	2.7e-11	0.90	0.04	0.96	FALSE
14	GTEx	Colon Transverse	PRELID1	0.31	0.28	lasso	4	0.26	1.1e-12	6.6	-6.7	1.8e-11	-0.90	0.03	0.97	FALSE
15	GTEx	Colon Transverse	MXD3	0.22	0.09	lasso	5	0.13	8.2e-07	4.8	5.2	1.6e-07	0.73	0.07	0.93	FALSE
16	GTEx	Esophagus Gastroesophageal Junction	MXD3	0.17	0.12	lasso	3	0.08	9.5e-04	6.6	5.6	2.6e-08	0.78	0.03	0.62	FALSE
17	GTEx	Esophagus Mucosa	UIMC1	0.08	0.00	lasso	5	0.00	3.5e-01	-6.5	-6.6	4.9e-11	-0.19	0.13	0.04	TRUE
18	GTEx	Esophagus Mucosa	FGFR4	0.18	0.16	enet	8	0.16	9.2e-11	-6.5	-6.2	4.5e-10	-0.21	0.94	0.06	FALSE
19	GTEx	Esophagus Mucosa	MXD3	0.16	0.14	lasso	8	0.15	1.7e-10	6.6	6.5	8.8e-11	0.85	0.25	0.74	FALSE
20	GTEx	Esophagus Muscularis	MXD3	0.27	0.20	enet	10	0.24	1.6e-14	6.6	6.8	7.5e-12	0.91	0.08	0.92	FALSE
21	GTEx	Heart Atrial Appendage	MXD3	0.33	0.15	enet	24	0.16	1.5e-07	6.6	6.3	3.1e-10	0.76	0.00	1.00	FALSE
22	GTEx	Heart Left Ventricle	MXD3	0.17	0.03	lasso	3	0.03	1.5e-02	6.6	6.5	5.7e-11	0.86	0.10	0.34	FALSE
23	GTEx	Liver	PRELID1	0.22	0.25	lasso	3	0.24	2.4e-07	7.8	-7.5	4.5e-14	-0.98	0.00	1.00	TRUE
24	GTEx	Lung	MXD3	0.20	0.12	lasso	10	0.12	1.8e-09	6.6	6.8	1.1e-11	0.85	0.12	0.88	FALSE
25	GTEx	Nerve Tibial	FGFR4	0.44	0.48	lasso	7	0.47	2.1e-37	-6.5	-6.4	2.0e-10	-0.19	0.94	0.06	FALSE
26	GTEx	Nerve Tibial	RAB24	0.27	0.08	enet	32	0.17	6.3e-12	2.0	7.1	1.4e-12	0.52	0.77	0.12	FALSE
27	GTEx	Nerve Tibial	MXD3	0.26	0.17	lasso	7	0.28	6.9e-20	6.6	7.1	1.0e-12	0.87	0.04	0.96	FALSE
28	GTEx	Pituitary	MXD3	0.25	0.20	lasso	6	0.16	7.5e-05	6.1	6.7	2.2e-11	0.74	0.03	0.91	FALSE
29	GTEx	Skin Not Sun Exposed Suprapubic	FGFR4	0.19	0.11	lasso	5	0.11	8.3e-07	-6.5	-5.4	5.8e-08	-0.18	0.87	0.05	FALSE
30	GTEx	Skin Not Sun Exposed Suprapubic	MXD3	0.22	0.18	lasso	3	0.17	1.8e-09	6.6	7.2	7.9e-13	0.94	0.01	0.99	FALSE
31	GTEx	Skin Sun Exposed Lower leg	PRELID1	0.06	0.02	enet	5	0.03	3.4e-03	6.6	-6.7	1.6e-11	-0.92	0.01	0.99	FALSE
32	GTEx	Skin Sun Exposed Lower leg	MXD3	0.19	0.14	lasso	6	0.12	4.2e-10	7.8	7.2	5.8e-13	0.91	0.00	1.00	FALSE
33	GTEx	Small Intestine Terminal Ileum	PRELID1	0.47	0.16	enet	10	0.13	7.6e-04	7.8	-7.3	2.7e-13	-0.94	0.00	0.97	FALSE
34	GTEx	Stomach	MXD3	0.21	0.03	lasso	7	0.08	1.4e-04	4.4	5.3	1.2e-07	0.76	0.07	0.88	FALSE
35	GTEx	Testis	DBN1	0.10	0.00	lasso	6	0.00	4.6e-01	6.2	-5.5	5.2e-08	-0.66	0.03	0.55	FALSE
36	GTEx	Thyroid	MXD3	0.31	0.17	lasso	8	0.24	1.1e-18	6.6	7.3	3.2e-13	0.91	0.00	1.00	FALSE
37	METSIM	Adipose	MXD3	0.18	0.18	lasso	3	0.21	1.3e-30	6.6	6.8	1.3e-11	0.86	0.72	0.28	FALSE
38	METSIM	Adipose	ZNF346	0.04	0.00	blup	373	0.03	9.6e-05	5.1	5.4	7.5e-08	0.38	0.67	0.04	TRUE
39	ROSMAP	Brain Pre-frontal Cortex	FGFR4	0.26	0.14	lasso	20	0.21	4.5e-26	-4.4	-5.1	2.8e-07	-0.23	1.00	0.00	FALSE
40	YFS	Blood	MXD3	0.04	0.03	lasso	4	0.04	5.8e-13	-2.8	5.6	2.1e-08	0.58	0.39	0.61	FALSE
41	The Cancer Genome Atlas	Colon Adenocarcinoma	PRELID1	0.09	0.01	blup	38	0.05	1.1e-03	6.9	-5.3	1.4e-07	-0.74	0.01	0.88	FALSE
42	The Cancer Genome Atlas	Colon Adenocarcinoma	RAB24	0.08	0.04	enet	7	0.06	3.4e-04	-3.1	6.3	2.9e-10	0.57	0.04	0.10	FALSE
43	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	FGFR4	0.08	0.06	blup	46	0.07	2.5e-08	3.7	-6.3	2.6e-10	-0.39	0.17	0.82	FALSE
44	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	LMAN2	0.04	0.00	blup	46	0.00	1.6e-01	7.8	-5.9	3.3e-09	-0.77	0.00	0.91	TRUE
45	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PRELID1	0.24	0.11	lasso	5	0.10	1.2e-11	6.9	-6.8	1.1e-11	-0.88	0.39	0.61	TRUE
46	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	PRELID1	0.33	0.08	enet	4	0.08	2.7e-05	6.6	-6.8	1.3e-11	-0.90	0.14	0.72	FALSE
47	The Cancer Genome Atlas	Brain Lower Grade Glioma	FGFR4	0.06	0.02	enet	7	0.05	1.2e-06	-2.2	-5.7	1.4e-08	-0.27	0.04	0.90	FALSE
48	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	PRELID1	0.08	0.10	lasso	4	0.07	2.9e-04	6.0	-6.2	4.2e-10	-0.83	0.02	0.92	FALSE
49	The Cancer Genome Atlas	Lung Adenocarcinoma	MXD3	0.04	0.02	blup	41	0.02	5.6e-04	4.7	5.6	1.7e-08	0.79	0.11	0.56	FALSE
50	The Cancer Genome Atlas	Prostate Adenocarcinoma	MXD3	0.04	0.02	blup	40	0.03	2.8e-04	6.6	6.3	2.7e-10	0.84	0.10	0.77	FALSE