TWAS hub - UIMC1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.1470	0.0300	2.8e-16	0.194	0.143	0.181	0.173	0.191	4.8e-23	4.3e-17	1.7e-21	1.7e-20	9.3e-23
2	GTEx	Adipose Subcutaneous	0.1210	0.0460	3.8e-04	0.029	NA	0.010	NA	0.023	1.9e-03	NA	5.1e-02	NA	5.0e-03
3	GTEx	Brain Cortex	0.2900	0.1410	6.1e-03	0.002	NA	0.012	NA	-0.010	2.8e-01	NA	1.4e-01	NA	8.0e-01
4	GTEx	Esophagus Mucosa	0.0770	0.0330	4.0e-03	0.001	NA	-0.001	NA	-0.001	2.9e-01	NA	3.6e-01	NA	3.5e-01
5	GTEx	Esophagus Muscularis	0.0930	0.0330	6.9e-04	0.055	NA	0.038	NA	0.026	2.8e-04	NA	2.3e-03	NA	9.7e-03
6	GTEx	Skin Not Sun Exposed Suprapubic	0.1460	0.0600	5.0e-03	-0.003	NA	0.000	NA	-0.005	5.1e-01	NA	3.1e-01	NA	8.0e-01
7	GTEx	Skin Sun Exposed Lower leg	0.1590	0.0430	1.5e-07	0.076	NA	0.139	NA	0.122	6.8e-07	NA	1.5e-11	NA	2.7e-10
8	GTEx	Testis	0.1260	0.0410	2.9e-04	0.179	NA	0.157	NA	0.063	2.2e-08	NA	1.9e-07	NA	8.9e-04
9	GTEx	Thyroid	0.1010	0.0330	6.5e-05	0.101	NA	0.087	NA	0.098	4.1e-08	NA	3.3e-07	NA	6.0e-08
10	METSIM	Adipose	0.0681	0.0205	1.3e-06	0.058	0.029	0.044	0.021	0.015	4.6e-09	3.3e-05	3.6e-07	2.9e-04	1.8e-03
11	YFS	Blood	0.0334	0.0116	2.5e-06	0.008	0.011	0.011	0.009	0.004	6.4e-04	1.2e-04	1.1e-04	4.1e-04	1.5e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	7	8	9	10	11
Had menopause	33.6	42.0	70.1	8.3	-7.9	-4.5	-3.1	-5.9	-6.7	-8.4	-8.2	-6.7	-6.3
Medication: Paracetamol	8.2	13.5	22.6	-4.6	4.8	3.1	0.7	4.4	2.8	4.7	4.6	4.3	2.5
Ever used hormone-replacement therapy (HRT)	7.8	9.9	15.5	3.9	-3.7	-3.2	-1.0	-3.9	-2.7	-3.6	-3.9	-3.5	-2.5
Medication: Paracetamol	7.2	11.1	18.9	-4.2	4.2	3.2	0.8	3.9	2.8	4.3	4.2	3.4	2.0
Seen a psychiatrist for nerves, anxiety, tension or depression	5.8	7.5	12.9	-3.1	2.8	3.6	2.5	2.5	3.0	3.0	3.0	3.2	1.8
Financial difficulties in last 2 years	5.7	7.6	12.4	-2.9	3.0	1.7	3.4	3.5	3.4	2.8	2.7	2.5	2.6
Height	5.6	107.3	585.1	8.7	-7.0	-6.5	-24.2	-9.7	-12.5	-8.5	-7.2	-5.9	-4.2
Number of incorrect matches in round	5.2	8.7	14.0	3.6	-3.4	0.4	-1.9	-3.7	-2.9	-3.4	-3.5	-3.3	-3.0
Medication: Ibuprofen	5.1	6.1	9.8	-2.9	2.7	2.3	0.9	3.0	2.2	2.9	2.9	3.1	2.3
Bilateral oophorectomy (both ovaries removed)	5.0	5.8	10.5	-2.8	2.8	2.1	1.4	3.2	2.6	3.0	2.7	2.6	1.5
Smoking status: Current	4.4	6.9	12.8	-3.4	3.4	1.1	0.6	3.6	2.7	3.3	3.5	2.5	1.4
Reaction Time	4.0	7.6	12.1	3.2	-2.9	-3.5	-1.6	-3.2	-3.3	-3.3	-3.1	-2.3	-1.7
Medication: Ibuprofen (e.g. Nurofen)	4.0	5.1	10.6	-2.6	2.6	1.7	0.3	3.3	1.7	2.6	2.6	3.0	1.6
Comparative height size at age 10	4.0	22.1	108.2	4.6	-3.9	-3.1	-10.4	-4.8	-4.1	-4.2	-3.9	-3.2	-2.5
Ever had hysterectomy (womb removed)	3.9	4.4	6.7	-2.3	2.3	2.4	2.1	2.3	2.6	2.5	2.2	2.0	1.1
Comparative body size at age 10	3.9	10.8	24.3	-3.7	3.1	2.7	4.9	3.7	4.4	3.6	3.4	2.1	1.6
Current tobacco smoking	3.8	6.3	13.1	-3.2	3.2	1.0	0.9	3.6	2.6	3.1	3.2	2.3	1.3
Standing height	3.8	37.8	237.5	4.7	-3.6	-3.9	-15.4	-5.3	-7.0	-4.7	-3.8	-3.2	-2.1
Medication for pain relief, constipation, heartburn	3.5	6.0	12.8	2.9	-3.2	-1.4	0.9	-2.4	-1.1	-3.1	-3.0	-3.6	-2.2
Heart disease (mother)	3.0	3.7	5.0	2.2	-2.1	-1.9	-1.6	-2.0	-2.2	-2.0	-2.2	-1.6	-2.1
Number of operations (self-reported)	2.8	4.2	8.1	-2.5	2.5	1.7	0.2	2.4	2.0	2.8	2.5	2.2	1.1
Age when periods started (menarche)	2.7	6.5	10.6	2.8	-2.7	-2.1	-1.4	-2.4	-3.3	-3.2	-2.8	-3.2	-2.1
Supplements: Calcium	2.7	3.0	7.2	-1.6	1.7	2.2	0.9	2.4	2.7	1.4	1.6	1.9	0.8
Neuroticism (2016)	2.5	3.6	7.2	-2.4	2.2	0.8	2.1	2.7	1.6	2.5	2.3	0.6	-1.2
Vitamin and mineral supplements	2.4	3.3	6.4	1.8	-1.9	-2.4	-1.8	-1.5	-2.5	-2.0	-1.7	-2.1	-0.1
Mean time to correctly identify matches	2.4	4.7	10.2	2.4	-2.0	-3.2	-1.9	-2.0	-2.6	-2.5	-2.3	-1.6	-1.7
Financial situation satisfaction	2.4	3.0	6.8	-2.0	2.2	1.1	0.9	2.6	2.0	2.1	1.9	1.7	0.9
Age at First Birth	2.3	3.3	5.2	2.3	-2.1	-1.0	-2.1	-2.1	-1.4	-2.2	-2.2	-1.7	-1.6
Medication: Co-codamol	2.3	2.6	4.1	-2.0	2.0	0.9	1.5	1.2	1.7	1.9	2.0	1.6	2.0
Supplements: Vitamin C	2.3	2.7	10.9	-1.2	0.9	0.8	3.3	1.9	2.6	1.5	0.9	1.4	-0.4
Fasting Glucose	2.2	2.7	8.2	-2.1	2.0	0.3	0.8	2.9	1.0	1.8	2.1	1.8	0.4
Trunk fat-free mass	2.2	12.5	61.1	2.6	-2.0	-3.1	-7.8	-3.4	-3.6	-2.3	-2.2	-3.1	-3.4
Waist Hip Ratio (WHR)	2.1	9.4	82.6	1.7	-1.0	1.0	-9.1	-1.8	-3.0	-1.4	-1.1	-0.3	-0.2
Frequency of unenthusiasm / disinterest in last 2 weeks	2.1	2.8	4.8	-2.1	2.1	1.8	-0.3	1.8	1.2	2.0	2.2	1.2	2.0
Leg predicted mass (left)	2.1	11.3	19.8	3.2	-2.7	-4.2	-4.5	-3.3	-3.1	-2.8	-2.9	-4.1	-4.0
Trunk predicted mass	2.1	12.0	60.1	2.5	-1.9	-3.1	-7.8	-3.2	-3.6	-2.1	-2.1	-3.1	-3.4
Blood clot in the leg (DVT)	2.1	2.7	5.2	-2.0	1.9	0.6	-0.9	1.4	1.4	1.9	2.1	1.8	2.3
Arm predicted mass (right)	2.1	10.5	39.7	2.6	-2.0	-3.7	-6.3	-2.9	-3.2	-2.3	-2.2	-3.1	-3.6
Whole body fat-free mass	2.1	11.9	43.2	2.9	-2.3	-3.7	-6.6	-3.3	-3.4	-2.5	-2.5	-3.5	-3.7
Leg fat-free mass (right)	2.1	11.0	19.9	3.1	-2.7	-4.3	-4.5	-3.3	-2.9	-2.8	-2.9	-4.0	-3.7
Back pain experienced in last month	2.1	3.1	8.7	-2.3	2.2	0.6	0.5	2.9	1.1	2.3	2.3	1.3	0.2
Whole body water mass	2.1	11.8	42.1	2.8	-2.2	-3.8	-6.5	-3.3	-3.3	-2.4	-2.4	-3.5	-3.7
Leg predicted mass (right)	2.1	11.3	20.3	3.2	-2.8	-4.4	-4.5	-3.4	-3.0	-2.8	-2.9	-4.0	-3.7
Arm predicted mass (left)	2.1	10.6	40.1	2.7	-2.1	-3.7	-6.3	-2.7	-3.3	-2.3	-2.3	-3.2	-3.6
Leg fat-free mass (left)	2.0	10.7	19.4	3.1	-2.6	-4.0	-4.4	-3.2	-3.0	-2.7	-2.8	-4.0	-3.9
Heart attack	2.0	2.6	5.6	-1.8	2.0	2.1	0.8	2.4	1.2	1.8	1.8	1.1	1.4
Arm fat-free mass (right)	2.0	10.0	39.6	2.4	-1.9	-3.8	-6.3	-2.7	-3.2	-2.2	-2.1	-3.0	-3.4
Basal metabolic rate	2.0	11.2	36.8	2.8	-2.2	-3.8	-6.1	-3.3	-3.4	-2.5	-2.4	-3.5	-3.5
Deep venous thrombosis (DVT) (self-reported)	2.0	2.6	5.3	-2.0	1.9	0.6	-0.6	1.4	1.5	1.9	2.1	1.7	2.3
Had other major operations	1.9	2.4	6.2	-1.6	1.5	-0.6	2.5	2.3	1.6	1.8	1.4	1.3	0.0
Hayfever/allergic rhinitis (self-reported)	1.9	2.5	7.8	-1.8	2.0	1.2	-0.4	0.5	1.2	1.7	1.9	1.9	2.8
Number of full brothers	1.9	2.4	4.0	-1.6	1.5	2.0	1.2	1.8	1.3	1.6	1.5	1.8	1.9
Guilty feelings	1.9	2.8	5.2	-2.2	2.3	0.8	0.2	2.2	1.8	2.1	2.3	1.4	0.8
Arm fat-free mass (left)	1.9	9.6	38.4	2.4	-1.9	-3.6	-6.2	-2.8	-3.0	-2.0	-2.1	-2.9	-3.4
Heart attack/myocardial infarction (self-reported)	1.9	2.5	6.1	-1.7	1.9	2.0	0.9	2.5	1.2	1.7	1.7	1.1	1.1
Fed-up feelings	1.8	3.2	6.1	-2.4	2.5	1.5	1.1	2.1	1.7	2.4	2.4	0.5	1.0
Neck or shoulder pain in last month	1.8	2.6	5.3	-1.8	1.8	1.8	1.0	2.3	1.4	2.0	1.9	1.4	0.9
Ever had bowel cancer screening	1.8	2.1	3.4	1.8	-1.8	-1.3	0.4	-1.8	-0.1	-1.9	-1.8	-1.7	-1.4
Hearing difficulty/problems: Yes	1.7	2.6	7.1	-1.7	1.9	0.2	1.0	1.5	2.7	1.6	1.7	1.3	2.2
Eye problems/disorders: Diabetes related eye disease	1.7	1.8	3.6	1.4	-1.6	-1.9	-1.1	-1.1	-1.7	-1.4	-1.3	-1.5	-1.0
Medication: Metformin	1.7	2.4	5.8	1.5	-1.4	-2.4	-1.6	-1.7	-1.6	-1.3	-1.4	-1.4	-1.6
Severe depression (siblings)	1.7	1.9	3.9	-1.8	1.6	-0.1	1.3	1.8	1.5	2.0	1.7	1.0	0.2
Ulcerative Colitis	1.6	2.3	8.1	1.8	-1.6	-0.4	-1.4	-2.8	-1.1	-1.5	-1.6	-1.6	-0.7
Alcohol usually taken with meals	1.6	2.6	6.4	2.2	-2.2	-0.7	-0.8	-2.1	-0.8	-2.5	-2.1	-1.4	-0.7
Weight	1.6	8.0	17.1	2.6	-2.1	-3.4	-4.1	-2.6	-3.1	-2.4	-2.4	-3.1	-3.3
Ever had prostate specific antigen (PSA) test	1.6	1.9	3.4	1.8	-1.8	0.3	-1.8	-1.7	-1.1	-1.7	-1.7	-1.1	-0.3
Depression (Nagel 2018)	1.5	2.3	4.0	-1.9	2.0	1.7	-0.0	1.9	1.5	1.6	2.0	0.9	1.4
HDL Cholesterol	1.5	2.5	4.0	2.0	-1.9	-1.6	-0.9	-1.9	-1.2	-1.8	-1.9	-2.0	-0.4
Smoking Status	1.5	3.6	7.4	-2.6	2.3	0.2	1.2	2.7	1.6	2.3	2.5	2.0	0.0
Long-standing illness, disability or infirmity	1.5	2.4	4.9	-2.0	2.2	-0.4	0.4	2.1	1.6	2.0	2.1	0.9	0.9
Multivitamins +/- minerals	1.4	1.8	3.4	-1.5	1.5	1.5	1.8	1.0	1.3	1.6	1.4	1.3	0.3
Chronic bronchitis/emphysema (father)	1.4	1.7	5.6	1.2	-1.3	-1.5	-0.4	-1.4	-1.3	-0.8	-1.3	-1.2	-2.4
Loud music exposure frequency	1.4	1.6	3.1	-1.4	1.4	0.1	1.8	1.6	1.6	1.4	1.3	1.0	0.3
Pulse wave peak to peak time	1.4	1.7	3.7	1.7	-1.9	-0.7	0.6	-0.8	-1.5	-1.7	-1.9	-1.1	-0.7
Number of full sisters	1.4	1.7	3.9	-1.6	1.5	-0.2	0.9	2.0	1.5	1.5	1.6	1.5	0.6
Frequency of tenseness / restlessness in last 2 weeks	1.3	2.0	3.4	-1.8	1.8	1.9	-0.7	1.4	0.7	1.7	1.8	1.0	1.3
Alcohol intake versus 10 years previously	1.3	2.0	4.5	-1.7	1.6	-0.1	0.8	0.7	1.2	1.7	1.7	2.1	1.9
Pulse wave Arterial Stiffness index	1.3	1.5	3.2	-1.5	1.7	0.6	-1.6	0.4	1.2	1.5	1.8	1.0	0.7
High blood pressure (siblings)	1.3	1.9	3.2	-1.7	1.3	-0.2	1.8	1.8	1.1	1.4	1.6	1.7	1.1
Health satisfaction	1.3	1.6	3.7	-1.8	1.9	0.1	-0.2	1.4	0.3	1.8	1.8	1.5	0.7
Forced expiratory volume in 1-second (FEV1), predicted	1.3	2.7	19.6	-1.1	1.3	-1.0	-4.4	0.5	-0.5	0.8	1.4	0.6	1.7
Commuting to job workplace: Public transport	1.3	1.6	3.6	1.6	-1.8	-0.2	0.0	-1.9	0.2	-1.6	-1.5	-1.3	-1.3
Pain type(s) experienced in last month: Hip pain	1.3	1.6	3.7	-1.8	1.8	0.5	0.3	1.4	1.3	1.9	1.8	0.5	0.4
Age started oral contraceptive pill	1.3	1.6	2.9	1.4	-1.0	-1.2	-1.6	-1.0	-1.7	-1.6	-1.3	-0.4	-1.5
Angina	1.2	1.6	3.0	-1.5	1.7	1.3	-0.0	1.1	0.6	1.4	1.5	1.3	1.7
Average weekly fortified wine intake	1.2	1.4	4.9	-1.3	1.3	0.6	-0.2	2.2	0.4	1.1	1.3	1.4	1.1
Forced vital capacity (FVC)	1.2	4.6	31.3	1.2	-1.0	-1.9	-5.6	-1.8	-2.1	-1.2	-0.9	-1.6	-0.2
Lung cancer (father)	1.2	1.4	2.1	-1.4	1.2	1.1	0.9	1.2	1.4	1.3	1.3	0.7	1.4
Medication: Aspirin	1.2	1.6	5.4	1.2	-0.9	-0.5	-2.3	-1.6	-1.8	-1.4	-1.0	-0.6	0.2
Average weekly beer plus cider intake	1.2	1.8	6.1	-1.3	1.5	0.1	2.5	1.2	1.6	1.5	1.1	0.7	1.3
Crohns Disease (2012)	1.1	1.8	3.7	1.6	-1.6	-1.9	-0.1	-1.6	-1.0	-1.1	-1.5	-0.8	-1.7
Primary Biliary Cirrhosis	1.1	1.6	6.2	-1.4	1.3	0.7	-0.1	0.0	2.5	1.6	1.5	0.9	1.3
Diverticular disease/diverticulitis (self-reported)	1.1	1.3	2.4	1.3	-1.2	-0.8	-0.8	-1.3	-1.0	-1.4	-1.3	-1.2	-1.5
Birth weight of first child	1.1	2.0	9.1	1.1	-0.7	-2.1	-3.0	-1.1	-1.2	-1.1	-0.9	-1.4	0.1
Angina (self-reported)	1.1	1.5	2.9	-1.5	1.7	1.2	0.2	1.3	0.6	1.3	1.5	1.1	1.5
Medication: Omeprazole	1.1	1.3	10.9	0.2	0.3	-0.2	-3.3	-1.1	-1.5	-0.1	-0.1	0.0	-0.2
Leg pain on walking	1.1	1.4	4.3	-1.5	1.5	-2.1	-0.1	0.5	0.5	1.5	1.6	0.6	0.8
Medication: Aspirin	1.1	1.4	4.9	1.2	-0.9	-0.9	-2.2	-1.4	-1.6	-1.3	-0.9	-0.5	0.4
Average weekly champagne plus white wine intake	1.1	1.6	3.5	1.5	-1.1	-0.7	-1.2	-1.9	-0.6	-1.7	-1.5	-1.5	-0.6
Miserableness	1.1	1.9	4.4	-1.8	1.8	2.1	1.0	1.6	1.0	1.7	1.8	0.1	-0.2
Body Mass Index (BMI) (2010)	1.0	1.3	9.2	-0.5	0.2	-0.1	3.0	0.9	1.3	0.6	0.3	-0.4	-1.4
Impedance of leg (right)	1.0	4.9	11.6	-1.4	1.5	3.4	-3.4	1.3	-1.0	0.8	1.6	3.0	3.3
Impedance of leg (left)	1.0	4.7	14.7	-1.4	1.4	2.9	-3.0	1.4	-0.8	0.8	1.6	3.2	3.8
Trunk fat mass	1.0	4.2	7.2	2.1	-1.7	-2.7	-1.9	-1.8	-2.3	-2.2	-2.0	-2.3	-2.2
Waist circumference	1.0	3.8	9.0	1.8	-1.3	-1.8	-3.0	-1.7	-1.9	-1.5	-1.6	-2.1	-2.9
Pulse wave reflection index	1.0	1.2	2.2	-1.3	1.4	1.1	0.5	0.8	1.5	1.2	1.4	1.1	0.8
Forced vital capacity (FVC), Best measure	1.0	3.7	21.8	1.3	-1.0	-1.5	-4.7	-1.5	-2.2	-1.3	-1.0	-2.0	-0.4
Had major operations	1.0	1.2	2.4	-1.4	1.5	0.6	-0.0	0.5	0.7	1.3	1.5	0.9	1.5
Illnesses of father: Heart disease	1.0	1.3	5.2	-0.7	0.6	2.3	2.0	0.9	0.9	0.6	0.5	1.3	0.9
Osteoporosis (self-reported)	1.0	1.2	3.7	-0.6	0.7	1.9	-0.1	1.3	0.8	0.5	0.6	1.4	1.9
Alzheimer’s Disease (in father)	0.9	0.9	2.2	-1.2	1.2	-0.3	-0.3	1.5	-0.2	0.8	1.2	0.9	1.4
Hip circumference	0.9	3.8	8.4	1.8	-1.7	-2.9	-0.2	-2.2	-1.8	-1.6	-1.8	-2.5	-2.7
Illnesses of mother	0.9	1.2	5.9	-0.4	0.2	2.4	0.0	0.1	1.3	0.4	0.4	0.7	2.1
Chest pain or discomfort	0.9	1.3	3.0	-1.4	1.6	1.3	0.7	1.7	0.5	1.3	1.3	0.7	0.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.0	2.9	-1.1	1.6	0.5	-1.7	0.3	0.1	1.0	1.3	0.9	0.6
Handedness (chirality/laterality): Left-handed	0.9	1.1	3.0	0.9	-1.2	-1.7	1.4	-0.8	-0.7	-1.2	-1.0	-0.7	-0.7
Medication: Gliclazide	0.9	1.0	3.8	0.7	-0.7	-2.0	0.7	-1.0	-0.7	-0.7	-0.8	-1.5	-1.0
Allergy or Eczema	0.8	2.2	8.3	1.3	-1.1	-2.0	-2.0	-2.9	0.7	-1.0	-1.1	-1.6	-0.2
Hypothyroidism (self reported)	0.8	1.8	3.9	1.2	-0.9	-2.0	-1.8	-1.6	-1.9	-1.3	-1.2	-1.0	-0.4
Hair/balding pattern: Pattern 3	0.8	1.2	2.6	-1.2	1.2	0.9	1.6	1.3	0.9	1.2	1.1	1.1	1.0
Noisy workplace	0.8	1.0	3.4	-1.2	1.2	0.0	1.5	1.8	0.3	1.1	1.1	0.5	-0.5
Qualifications: O levels/GCSEs or equivalent	0.8	1.2	2.6	-1.1	0.9	1.2	0.7	1.6	1.5	0.9	1.1	1.0	1.3
Qualifications: College or University degree	0.8	2.5	5.0	2.2	-2.0	-0.9	-1.8	-1.8	-0.8	-2.2	-2.1	-1.0	-0.4
Breast cancer (self-reported)	0.8	1.0	2.5	-1.1	1.1	0.5	0.9	0.7	1.6	1.2	1.1	0.8	1.1
Medication: Atorvastatin	0.8	1.0	2.1	-1.2	1.2	0.4	0.9	1.4	1.4	1.2	1.2	0.7	0.4
Alcohol drinker status: Never	0.8	1.0	2.4	-1.1	1.4	1.6	-0.3	1.0	0.4	1.4	1.2	-0.0	-0.9
Myopia	0.8	1.1	8.6	0.5	-0.3	0.1	0.8	-1.0	0.4	-0.7	-0.5	-0.6	2.9
Medication: Omeprazole (e.g. Zanprol)	0.8	0.9	6.1	-0.6	1.0	-0.5	-2.5	0.1	-0.9	0.6	0.8	0.8	0.5
Ulcerative Colitis (UC)	0.7	1.4	7.6	0.9	-0.9	-0.5	-1.6	-2.8	-1.1	-0.7	-0.8	-0.9	-0.1
Coronary Artery Disease (CAD)	0.7	0.8	2.2	0.6	-0.5	-1.4	-0.8	-1.5	-1.1	-0.7	-0.5	-1.1	-0.8
Lupus	0.7	1.1	2.2	-1.2	1.5	0.1	-0.1	1.3	1.3	1.2	1.1	0.8	1.1
Blood Eosinophil Count	0.7	5.8	19.8	2.8	-2.7	-1.3	-1.2	-4.5	-1.6	-2.6	-2.7	-2.4	-1.6
Blood Red Count	0.7	6.7	36.8	2.2	-2.1	-1.5	-1.0	-6.1	-1.5	-2.1	-2.1	-3.0	-2.1
Heel T-Score	0.7	5.2	9.2	-3.0	2.7	-1.0	3.0	0.6	2.3	2.8	2.9	2.7	1.4
Frequency of depressed mood in last 2 weeks	0.7	0.9	5.3	-0.8	0.6	2.3	0.4	0.9	1.1	0.7	0.8	0.3	0.6
Townsend deprivation index at recruitment	0.7	1.0	3.7	-0.8	0.9	1.9	1.1	1.0	1.0	1.1	0.7	1.2	-0.2
Qualifications: CSEs or equivalent	0.7	0.9	4.3	-0.9	0.8	1.0	2.1	0.7	0.4	1.0	0.8	0.6	-0.7
Time employed in main current job	0.7	0.8	2.0	0.6	-0.8	-0.8	-1.4	-1.2	-1.4	-0.6	-0.5	-0.3	-0.8
Father’s age at death	0.7	0.9	2.5	1.2	-1.2	-0.3	-0.0	-1.6	-0.5	-1.3	-1.3	-0.6	-0.6
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	2.7	-1.2	1.0	1.3	1.6	1.5	0.4	1.2	1.1	0.2	0.3
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	3.7	0.6	-0.6	-1.0	1.9	-0.2	-0.0	-0.9	-0.7	-0.0	-1.3
Depression (self-reported)	0.7	0.8	5.5	-0.5	0.5	1.2	2.4	0.5	0.9	0.4	0.3	0.1	-0.0
Birth weight	0.7	1.5	7.7	1.1	-1.3	-2.8	-0.5	-0.9	-1.0	-1.2	-1.1	-0.9	0.6
Whole body fat mass	0.7	2.8	5.0	1.6	-1.3	-2.2	-1.3	-1.5	-1.8	-1.6	-1.5	-2.0	-2.2
Number of self-reported non-cancer illnesses	0.7	1.3	2.4	-1.4	1.6	0.5	1.0	0.4	1.5	1.3	1.5	1.0	0.9
Hearing aid user	0.7	0.8	2.8	0.3	-0.3	-1.7	1.6	1.0	-0.6	-0.3	-0.5	-0.8	-0.7
Irritability	0.7	1.2	2.3	-1.5	1.3	-0.8	1.0	1.4	0.8	1.3	1.5	0.4	0.7
Unable to work because of sickness or disability	0.7	0.9	4.7	0.6	-0.5	-0.9	-0.3	-0.3	-2.2	-0.8	-0.6	-1.1	-1.0
Irritable Bowel Disease (IBD)	0.6	1.3	7.3	0.9	-1.1	-0.9	-0.7	-2.7	-0.7	-0.6	-0.9	-0.8	-1.4
Lung FEV1/FVC ratio	0.6	3.2	15.9	-1.1	0.8	-1.1	2.5	4.0	1.2	0.9	0.9	1.8	1.9
Neuroticism	0.6	1.5	4.1	-1.6	1.6	-0.8	-0.3	2.0	0.6	1.5	1.7	-0.6	-0.7
Other serious medical condition/disability diagnosed by doctor	0.6	0.8	6.2	0.3	-0.1	0.8	-2.5	-1.2	0.1	-0.2	-0.1	-0.4	-0.5
Trunk fat percentage	0.6	2.4	4.3	1.8	-1.6	-2.1	0.1	-1.2	-1.7	-1.9	-1.8	-1.7	-1.4
Hand grip strength (right)	0.6	1.6	6.5	1.1	-1.2	-1.0	-2.5	-1.6	-0.6	-0.9	-0.9	-0.7	-1.4
Taking other prescription medications	0.6	0.9	2.2	-1.2	1.5	-0.5	-1.3	0.1	0.3	1.3	1.3	0.7	0.2
High blood pressure	0.6	1.7	7.2	1.1	-1.2	-1.9	-0.0	-0.7	-0.8	-1.1	-1.1	-1.2	-2.7
Diabetes (self-reported)	0.6	0.9	3.7	0.7	-0.9	-1.9	0.1	-1.0	-0.7	-0.7	-0.7	-1.3	-0.8
Neuroticism score	0.6	1.2	2.7	-1.6	1.5	0.5	0.3	1.3	1.0	1.5	1.6	0.0	0.1
Forced expiratory volume in 1-second (FEV1)	0.6	1.9	14.9	0.5	-0.6	-1.4	-3.9	-0.6	-1.4	-0.6	-0.3	-0.5	0.7
Arm fat mass (right)	0.6	2.6	6.3	1.5	-1.2	-2.3	-0.0	-1.5	-1.4	-1.3	-1.5	-2.2	-2.5
Hypothyroidism/myxoedema (self-reported)	0.6	1.2	3.9	0.9	-0.8	-2.0	-1.4	-1.4	-1.5	-1.0	-0.9	-0.4	-0.3
Wheeze or whistling in the chest in last year	0.6	1.0	7.7	0.2	0.1	-0.8	-2.8	-1.3	-0.4	0.1	0.1	-0.5	-0.9
Age at first live birth	0.6	1.1	3.1	1.3	-1.1	-0.5	-1.8	-1.3	-0.1	-1.4	-1.2	-0.4	0.7
Age at last live birth	0.6	0.9	4.2	-0.8	0.8	0.3	-0.4	0.4	1.3	0.7	0.9	1.2	2.1
Family relationship satisfaction	0.6	0.8	2.6	-0.9	0.9	1.6	-0.0	0.6	1.1	0.8	1.0	0.6	-0.6
Qualifications: NVQ or HND or HNC or equivalent	0.6	0.7	2.8	-0.8	0.5	-0.2	1.7	1.1	1.1	0.8	0.7	0.6	-0.2
Illness, injury, bereavement, stress in last 2 years	0.6	0.8	2.0	0.8	-0.8	-0.3	-1.4	-0.8	-1.4	-0.8	-0.7	-0.6	-1.1
Knee pain experienced in last month	0.6	1.0	4.8	0.8	-0.5	0.5	-2.2	-2.0	-0.2	-0.7	-0.6	-0.5	0.3
Hypertension (Self-reported)	0.6	1.6	7.1	1.2	-1.2	-1.4	0.6	-0.6	-0.8	-1.1	-1.2	-1.4	-2.7
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	2.0	-0.7	0.7	1.1	0.3	0.7	0.4	0.7	0.7	1.4	0.9
Commuting to job workplace: Walk	0.6	0.6	3.8	0.6	-0.6	-2.0	-0.7	-0.9	-0.2	-0.5	-0.5	-0.8	0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.2	3.4	0.8	-1.1	-1.8	1.2	-0.0	-1.6	-1.1	-1.0	-1.2	-0.6
Arm fat mass (left)	0.6	2.4	6.4	1.4	-1.1	-2.3	-0.0	-1.3	-1.2	-1.2	-1.4	-2.2	-2.5
Cholesterol lowering medication	0.6	0.8	2.5	-0.9	1.1	-1.0	-1.6	-0.1	0.1	1.0	1.1	0.9	0.7
Schizophrenia (2018)	0.5	1.0	2.1	1.3	-1.1	1.4	0.6	-0.2	-0.5	-1.2	-1.4	-1.2	-0.4
LDL Cholesterol	0.5	0.8	1.7	-0.9	1.0	1.3	-0.5	0.9	0.6	1.0	1.0	1.3	-0.2
Hand grip strength (left)	0.5	1.4	4.7	1.0	-1.1	-1.4	-2.2	-1.5	-0.5	-1.0	-0.9	-0.9	-0.9
Number of treatments/medications taken	0.5	0.9	2.3	-1.3	1.5	-0.1	-0.8	0.8	0.5	1.3	1.5	0.6	0.5
Average weekly spirits intake	0.5	0.6	2.0	-0.8	1.1	-0.7	-1.4	0.9	0.2	0.9	0.9	0.3	0.0
Maternal smoking around birth	0.5	0.7	1.6	-1.1	1.1	0.3	0.1	0.8	1.0	1.1	1.1	1.3	-0.2
Hayfever, allergic rhinitis or eczema	0.5	1.1	4.1	0.7	-0.5	-1.1	-2.0	-2.0	0.5	-0.5	-0.5	-1.1	0.0
High blood pressure (mother)	0.5	0.8	3.3	-0.5	0.4	-1.8	1.8	0.8	0.5	0.4	0.4	0.2	-0.4
Body mass index (BMI)	0.5	2.1	8.6	0.5	-0.5	-1.8	2.9	-0.3	-0.0	-0.3	-0.8	-1.8	-2.6
Qualifications: None of the above	0.5	1.0	2.6	-1.5	1.5	-0.7	-0.2	0.7	0.0	1.6	1.5	1.0	0.5
Pain all over the body in last month	0.5	0.5	3.2	0.3	-0.3	0.2	-0.5	0.2	-1.0	-0.1	-0.3	-0.8	-1.8
Mouth/teeth dental problems: Dentures	0.5	0.9	2.5	-1.1	1.1	-0.1	0.9	0.8	1.6	1.2	1.1	0.7	0.3
Chronic bronchitis/emphysema (mother)	0.5	0.6	3.6	-0.1	0.2	-0.0	-1.9	-1.1	-0.5	0.3	0.3	-0.2	-1.3
Exposure to tobacco smoke outside home	0.5	0.7	1.4	-1.2	1.0	-0.2	0.4	1.0	0.9	1.0	1.1	0.6	0.9
Worry too long after embarrassment	0.5	0.9	3.5	0.6	-0.4	-1.1	-0.7	0.5	-0.8	-0.9	-0.5	-1.6	-1.9
Number of children fathered	0.5	0.6	2.1	0.7	-0.4	-0.5	-0.5	0.0	-1.2	-0.7	-0.8	-0.7	-1.4
Shortness of breath walking on level ground	0.5	0.6	1.6	-0.9	1.0	0.1	0.4	1.3	0.5	1.1	0.9	0.0	-0.5
Eye problems/disorders: None of the above	0.5	0.6	2.5	-0.4	0.3	1.2	1.6	-0.3	0.6	0.4	0.2	0.7	0.9
Medication: Allopurinol	0.5	0.7	1.5	1.0	-1.1	0.1	0.4	-0.0	-1.0	-1.0	-1.0	-1.2	-0.9
Leg fat mass (right)	0.5	1.9	4.5	1.1	-0.7	-2.0	-1.0	-1.1	-1.6	-1.1	-1.1	-1.9	-2.1
Overall health rating	0.5	1.0	2.8	-1.3	1.7	-0.0	-0.9	1.3	0.1	1.5	1.4	-0.0	0.1
Loneliness, isolation	0.5	0.7	5.3	-0.7	0.4	2.3	-0.3	0.2	0.7	0.5	0.8	-0.0	-0.1
Friendships satisfaction	0.5	0.7	5.0	0.5	-0.4	-0.7	-2.2	-1.1	-0.2	-0.4	-0.2	-0.3	-0.2
Illnesses of father: High blood pressure	0.5	0.6	2.4	0.3	-0.5	1.3	1.0	-0.2	0.7	0.1	-0.4	-0.2	-1.6
Impedance of whole body	0.5	2.6	10.5	-0.2	0.2	2.1	-2.5	0.6	-1.4	-0.3	0.4	2.1	3.2
Leg fat mass (left)	0.5	1.9	4.5	1.1	-0.8	-2.1	-0.8	-1.1	-1.5	-1.1	-1.1	-1.9	-2.0
Depressed Affect (Nagel 2018)	0.4	0.8	2.0	-1.0	1.1	1.0	-0.2	1.4	0.6	0.8	1.1	-1.1	-0.3
Major Depression (MDD)	0.4	0.5	1.3	-0.8	0.9	0.0	0.5	0.8	1.2	0.7	0.8	0.6	0.5
Schizophrenia (2014)	0.4	0.9	2.3	1.4	-1.3	0.8	0.6	-0.3	-0.5	-1.2	-1.5	-1.0	-0.5
BMI	0.4	2.2	14.8	0.1	-0.2	-1.3	3.9	0.1	0.5	0.1	-0.3	-1.8	-2.2
Sensitivity / hurt feelings	0.4	0.6	2.3	0.7	-0.7	-0.5	-1.5	-0.5	-0.6	-0.7	-0.5	-1.1	-0.8
Systolic blood pressure, automated reading	0.4	1.0	3.6	-0.7	0.7	-0.9	1.9	0.9	1.5	1.1	0.7	0.2	-1.1
Diabetes (mother)	0.4	0.5	2.9	-0.7	0.5	-0.1	1.7	0.5	0.1	0.7	0.6	0.8	0.5
Pack years adult smoking proportion	0.4	0.6	3.5	-0.2	0.3	-1.3	-1.9	-0.2	-0.8	0.2	0.3	0.3	-0.3
Relative age voice broke	0.4	0.6	1.3	-0.6	0.9	0.8	-1.0	0.8	0.1	0.7	0.7	1.0	1.1
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	1.5	-0.7	0.7	1.2	-0.3	0.2	-0.6	0.4	0.7	0.7	0.8
Medication: Levothyroxine sodium	0.4	0.6	3.9	0.6	-0.6	-2.0	-0.4	-0.5	-0.9	-0.6	-0.6	-0.4	-0.5
Sitting height	0.4	2.9	7.6	1.7	-1.6	-2.8	-2.1	-1.0	-1.4	-1.5	-1.6	-1.1	-2.4
Past tobacco smoking	0.4	0.7	2.3	0.8	-0.7	-0.1	-1.4	-1.5	-0.5	-0.8	-0.7	-0.6	0.6
Illnesses of siblings	0.4	0.6	1.4	0.9	-0.7	0.6	-0.4	-1.2	-0.6	-0.7	-1.0	-0.7	0.6
Arm fat percentage (right)	0.4	1.4	7.1	0.8	-0.7	-1.0	2.7	-0.7	-0.4	-0.8	-0.9	-1.5	-1.6
Worrier / anxious feelings	0.4	0.8	2.5	0.9	-0.8	0.4	-1.6	-0.8	-1.2	-1.0	-0.8	-1.0	-0.5
Asthma	0.4	0.8	3.0	1.0	-0.6	-1.4	-0.3	-1.7	0.0	-0.7	-0.9	-0.7	-0.8
Forced expiratory volume in 1-second (FEV1), Best measure	0.4	1.1	7.7	0.3	-0.3	-1.3	-2.8	0.2	-1.2	-0.4	-0.2	-0.9	0.5
Hair/balding pattern: Pattern 4	0.4	1.0	2.5	0.9	-1.0	-1.1	-1.4	-0.4	-1.6	-1.0	-0.9	-0.4	-1.1
Peak expiratory flow (PEF)	0.4	0.8	5.3	0.5	-0.7	-0.5	-2.3	-1.1	-0.5	-0.4	-0.4	-0.4	1.0
Mouth/teeth dental problems: Loose teeth	0.4	0.4	1.1	0.8	-0.7	-0.2	-0.7	-1.0	-0.2	-1.0	-0.7	-0.4	0.2
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.4	0.5	1.0	0.8	-0.7	-0.5	0.9	-0.4	0.1	-0.9	-0.9	-1.0	-0.3
Arm fat percentage (left)	0.4	1.5	6.9	0.7	-0.6	-1.3	2.6	-0.6	-0.3	-0.7	-0.9	-1.5	-1.7
Diabetes diagnosed by doctor	0.4	0.7	3.3	0.4	-0.5	-1.8	-0.3	-1.0	-0.4	-0.4	-0.4	-1.4	-0.7
Mouth/teeth dental problems: Mouth ulcers	0.4	0.6	1.0	1.0	-0.7	-0.9	-0.1	1.0	-0.3	-0.8	-0.9	-0.9	-1.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.4	2.4	-0.0	0.5	0.1	-1.5	0.9	-0.9	0.1	0.1	0.4	-0.4
Mineral and other dietary supplements	0.4	0.5	1.9	0.6	-0.5	-1.2	-0.5	-0.1	-1.4	-0.8	-0.6	-0.1	0.8
Ever taken oral contraceptive pill	0.4	0.5	2.5	-0.3	0.5	1.6	0.2	-0.2	0.5	0.2	0.3	1.2	0.7
Medication: Blood pressure	0.4	0.8	2.6	0.8	-0.8	-1.3	-0.0	-0.6	-0.8	-0.7	-0.8	-0.9	-1.6
Ever depressed for a whole week	0.4	0.5	1.2	-1.0	0.9	-0.2	0.1	0.5	0.9	1.1	1.1	0.3	0.2
Pain experienced in last month	0.4	0.6	1.7	1.1	-1.0	-0.1	0.5	-1.3	-0.3	-1.2	-1.1	0.2	0.1
Heart disease (siblings)	0.4	0.5	2.1	0.5	-0.1	1.0	-1.5	-0.9	-0.4	-0.6	-0.3	-0.2	-1.0
Pack years of smoking	0.4	0.6	4.2	-0.5	0.6	-0.8	-2.1	-0.2	-0.6	0.5	0.6	0.7	-0.0
Bipolar Disorder or Schizophrenia	0.3	0.7	1.9	1.0	-1.1	1.4	0.8	-0.6	0.7	-0.8	-1.1	-0.6	0.0
Alzheimer’s Disease (in mother)	0.3	0.3	2.3	-0.1	-0.1	-0.8	1.5	0.5	0.1	-0.1	0.0	0.4	-0.6
Verbal and Numeric Reasoning (VNR)	0.3	0.8	6.9	0.2	0.0	-0.7	-2.6	-0.6	0.0	-0.0	0.0	-0.6	0.3
Prostate Cancer	0.3	0.4	2.0	0.2	-0.1	-1.4	-0.8	-1.1	-0.3	-0.2	-0.1	-0.6	0.5
Mean Putamen Volume	0.3	0.3	1.1	-0.0	0.4	-1.0	-1.1	0.1	0.1	0.1	0.1	0.5	1.1
HbA1C	0.3	0.3	1.1	0.4	-0.4	0.8	-0.5	-0.5	-0.7	-0.3	-0.4	-1.1	-0.1
Rheumatoid Arthritis	0.3	0.4	1.3	-0.3	0.4	1.2	-0.8	-0.9	0.1	0.4	0.4	0.0	0.7
Supplements: Zinc	0.3	0.3	0.9	-0.2	0.2	-0.4	0.9	0.4	0.8	0.4	0.3	0.6	-0.8
Diabetes (father)	0.3	0.3	2.3	0.3	-0.4	0.6	-0.2	-1.5	0.0	-0.2	-0.3	0.0	-0.6
Serious illness, injury or assault to yourself	0.3	0.4	1.0	-0.6	0.6	0.6	-1.0	-0.5	0.5	0.7	0.7	0.6	0.6
Supplements: Glucosamine	0.3	0.4	1.7	0.7	-0.7	-0.3	-0.1	0.1	0.5	-0.7	-0.6	-1.3	-0.1
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.3	-0.7	0.6	-0.7	-0.4	-0.2	0.6	0.5	0.7	0.1	1.1
Allergy	0.3	0.7	3.0	-0.5	0.2	0.8	1.5	1.7	-1.1	0.3	0.3	0.6	0.1
Medication: Ramipril	0.3	0.4	1.1	0.6	-0.7	-0.0	0.1	-0.7	-1.0	-0.8	-0.6	-0.8	-0.2
Fluid intelligence score	0.3	0.6	5.0	0.4	-0.4	0.2	-2.2	-1.0	0.1	-0.1	-0.2	-0.1	0.3
Impedance of arm (right)	0.3	1.3	5.6	0.5	-0.5	1.8	-1.1	-0.1	-1.2	-0.9	-0.4	1.1	2.4
Falls in the last year	0.3	0.4	0.9	0.7	-0.4	-0.9	-0.5	-0.9	-0.3	-0.8	-0.7	-0.6	0.1
Number of live births	0.3	0.5	0.9	-0.6	0.9	0.9	-0.8	0.6	0.4	1.0	0.6	0.7	-0.5
Happiness	0.3	0.4	2.7	0.6	-0.4	0.5	-0.2	0.1	-0.4	-0.4	-0.5	-0.4	-1.6
Medication: Lansoprazole	0.3	0.4	0.8	-0.7	0.7	-0.5	-0.1	0.5	-0.3	0.6	0.7	0.9	0.8
Prospective memory result	0.3	0.4	1.0	-0.7	0.7	-0.2	0.5	1.0	0.5	0.5	0.6	0.7	0.9
Impedance of arm (left)	0.3	1.2	4.1	0.7	-0.7	1.1	-1.4	-0.3	-1.5	-1.1	-0.6	0.7	2.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.5	2.7	-0.7	0.5	0.7	1.6	0.3	0.6	0.6	0.6	-0.3	-0.5
Gout (self-reported)	0.3	0.4	0.8	0.8	-0.9	-0.0	-0.1	-0.6	-0.7	-0.9	-0.7	-0.7	-0.4
Body fat percentage	0.3	1.1	2.2	1.0	-0.8	-1.5	0.7	-0.7	-1.1	-1.2	-1.1	-1.2	-1.2
Migraine (self-reported)	0.3	0.3	1.1	-0.7	0.5	-0.3	0.7	0.5	1.0	0.6	0.7	0.0	0.1
Pulse rate, automated reading	0.3	0.9	2.8	-1.1	1.3	-0.8	-1.7	0.5	0.0	1.3	1.3	-0.4	-0.1
Commuting to job workplace: Car/motor vehicle	0.3	0.3	2.0	-0.2	0.2	0.9	0.2	1.4	-0.4	0.3	0.1	0.0	-0.5
Illnesses of siblings: Diabetes	0.3	0.4	2.0	-0.3	0.3	-1.4	-0.5	0.5	-0.1	0.4	0.3	-0.5	-1.2
Smoking status: Previous	0.3	0.4	1.8	0.3	-0.4	-0.2	1.4	0.3	-0.6	-0.3	-0.4	-0.1	-1.1
Mood swings	0.3	0.6	2.2	-0.8	0.8	1.5	0.0	0.9	0.7	0.8	0.9	-0.6	0.1
Qualifications: nursing, teaching	0.3	0.5	1.1	0.7	-0.5	-0.5	-1.1	-1.0	-0.5	-0.8	-0.6	0.4	1.1
Eye problems/disorders: Cataract	0.3	0.3	0.9	0.1	-0.4	0.4	-0.9	0.9	-0.1	0.1	0.1	-0.5	-1.0
Asthma (self-reported)	0.3	0.7	2.6	0.9	-0.6	-1.3	-0.1	-1.6	0.1	-0.6	-0.9	-0.6	-0.8
Tinnitus: Yes, now most or all of the time	0.3	0.3	1.4	-0.6	0.5	0.3	0.3	0.7	1.2	0.7	0.7	0.2	0.1
Risk taking	0.3	0.4	1.5	-0.5	0.3	-0.2	0.6	1.1	1.2	0.5	0.5	0.6	-0.3
Diastolic blood pressure, automated reading	0.3	0.9	3.0	0.8	-0.6	-1.7	0.9	-0.7	0.1	-0.5	-0.8	-0.9	-1.6
Vascular/heart problems diagnosed by doctor	0.3	0.9	3.1	-0.8	0.8	1.4	0.0	0.5	1.1	0.8	0.7	1.0	1.8
Bipolar Disorder (2018)	0.2	0.4	2.9	0.0	-0.3	0.3	0.5	-0.8	1.7	0.2	0.0	0.3	0.5
Intelligence (Savage-Jansen 2018)	0.2	0.7	5.8	0.2	-0.2	-0.3	-2.4	-0.2	-0.0	-0.2	0.1	-0.2	1.3
Neuroticism (Nagel 2018)	0.2	0.5	1.0	-0.8	0.9	-0.3	-0.9	1.0	0.1	0.6	0.9	-1.0	-0.1
Alzheimer’s Disease (including proxy)	0.2	0.3	1.3	-0.0	-0.1	-1.1	1.1	0.6	-0.8	-0.5	-0.0	0.2	-0.0
Crohns Disease (2017)	0.2	0.4	2.3	0.2	-0.4	-0.4	0.4	-1.1	0.1	0.2	-0.2	0.3	-1.5
Ovarian Cancer	0.2	0.3	0.7	-0.7	0.6	-0.4	-0.7	0.7	0.4	0.5	0.8	0.6	0.4
Respiratory disease	0.2	0.4	1.6	0.4	-0.0	-1.3	0.1	-1.0	0.5	-0.1	-0.4	-0.3	-0.8
Type 2 Diabetes (T2D) (2018)	0.2	0.3	1.5	0.1	-0.3	-1.2	0.1	-0.7	-0.2	-0.2	-0.1	-1.1	-0.3
Tanning	0.2	2.0	3.7	1.4	-1.8	-1.9	1.1	-0.6	-1.6	-1.5	-1.6	-1.3	-1.8
Stomach or abdominal pain in last month	0.2	0.3	2.3	-0.0	-0.0	-0.1	-0.4	-0.2	-0.2	0.1	0.1	-0.9	1.5
Hair/balding pattern: Pattern 2	0.2	0.3	0.7	0.6	-0.6	0.6	-0.1	-0.8	0.4	-0.6	-0.6	-0.3	-0.8
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.6	3.2	0.3	-0.2	-1.8	0.3	-1.5	-0.2	-0.4	-0.3	0.0	0.0
Mouth/teeth dental problems	0.2	0.3	0.9	0.4	-0.4	1.0	-0.2	-0.8	-0.8	-0.5	-0.4	-0.0	0.4
Qualifications: A levels/AS levels or equivalent	0.2	0.5	2.1	0.5	-0.9	0.2	0.4	-1.5	0.2	-0.7	-0.6	0.5	1.2
Length of working week for main job	0.2	0.2	0.9	-0.3	0.4	0.7	-0.7	-0.5	-0.2	0.2	0.3	0.9	0.4
Breastfed as a baby	0.2	0.3	1.2	0.7	-0.5	-1.1	-0.2	0.1	0.2	-0.6	-0.6	0.1	0.7
Tense / ‘highly strung’	0.2	0.3	1.4	0.4	-0.4	0.1	0.6	-0.7	-0.2	-0.3	-0.5	-0.9	-1.2
Ever highly irritable/argumentative for 2 days	0.2	0.3	1.3	-0.0	-0.1	-1.0	0.6	0.6	-0.3	0.1	-0.1	-1.1	-0.2
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	1.2	0.3	-0.6	-1.1	0.8	0.1	0.2	-0.3	-0.4	0.0	-0.9
Headache pain in last month	0.2	0.3	1.0	0.2	-0.3	-0.3	-0.9	-0.2	-0.6	-0.1	-0.1	-0.6	-1.0
Medication: Amlodipine	0.2	0.3	1.1	0.4	-0.5	-1.1	0.0	-0.7	-1.1	-0.3	-0.3	-0.1	-0.4
Medication: Ventolin 100micrograms inhaler	0.2	0.3	1.0	0.1	0.0	-0.8	0.8	0.1	-0.3	-0.2	-0.2	-1.0	-0.7
Alcohol intake frequency.	0.2	0.5	1.8	0.4	-0.4	-0.8	-0.5	-1.4	-0.0	0.1	-0.3	-0.9	-1.1
Medication for cholesterol	0.2	0.4	3.1	0.1	-0.1	1.7	0.7	0.0	0.6	-0.0	-0.1	-0.1	0.4
Osteoarthritis (self-reported)	0.2	0.2	0.8	-0.2	0.7	-0.0	-0.9	-0.2	0.7	0.4	0.4	-0.0	0.4
Wears glasses or contact lenses	0.2	0.3	0.8	0.0	-0.0	-0.9	0.6	0.5	-0.7	-0.1	-0.1	0.5	0.8
Eye problems/disorders: Glaucoma	0.2	0.2	0.6	0.5	-0.1	0.5	-0.7	-0.3	-0.1	-0.5	-0.4	-0.5	-0.8
High cholesterol (Self-reported)	0.2	0.4	0.9	-0.8	0.9	-0.2	-0.4	0.4	0.5	0.8	0.8	0.6	0.8
Medication: Lisinopril	0.2	0.2	0.9	0.2	-0.3	-0.9	0.6	0.1	0.6	-0.2	-0.3	-0.4	-0.8
Ever smoked	0.2	0.3	1.7	-0.2	0.1	-0.4	1.3	1.1	-0.1	0.2	0.2	-0.0	-0.7
Fractured/broken bones in last 5 years	0.2	0.3	2.7	0.0	-0.0	1.6	0.0	-0.1	0.3	-0.0	-0.1	0.3	0.3
Basal cell carcinoma (self-reported)	0.2	0.2	0.9	0.2	-0.1	-0.6	-1.0	0.2	-0.5	-0.1	-0.2	-0.3	-0.8
Schizophrenia vs Biploar Disorder	0.1	0.2	0.9	-0.4	0.4	-0.0	-0.4	1.0	-0.5	0.2	0.4	0.1	0.4
Worry (Nagel 2018)	0.1	0.1	0.3	-0.4	0.4	-0.3	0.0	-0.3	0.1	0.5	0.5	-0.3	0.6
Breast Cancer	0.1	0.2	2.3	0.2	-0.1	0.0	-0.0	0.0	-1.5	-0.4	-0.2	-0.3	-0.1
Triglycerides	0.1	0.2	0.6	0.4	-0.3	-0.6	0.2	-0.8	0.1	-0.2	-0.4	-0.2	-0.6
Type 2 Diabetes (T2D) (2012)	0.1	0.2	0.9	-0.1	0.1	0.1	0.3	-1.0	0.4	0.2	0.2	0.5	0.4
Blood Platelet Count	0.1	1.4	6.9	-0.0	-0.1	1.0	2.6	0.4	1.0	0.0	-0.2	1.4	2.1
Blood White Count	0.1	0.8	1.9	-1.1	0.8	0.6	-0.4	-1.4	1.0	1.4	1.1	0.7	0.4
Systolic Blood Pressure	0.1	0.5	1.1	-0.7	0.5	-0.8	0.9	0.2	1.0	1.0	0.7	0.6	0.1
Cardiovascular Disease	0.1	0.5	3.4	0.3	-0.3	-0.2	0.8	0.3	-0.5	-0.3	-0.3	-0.6	-1.8
Lung FVC	0.1	0.3	0.9	-0.5	0.3	-0.9	0.4	1.0	0.8	0.5	0.5	-0.4	-0.5
Chronotype (morning person)	0.1	0.2	0.7	-0.3	0.5	0.9	0.1	0.5	-0.6	0.1	0.3	0.7	0.2
Hair Pigment	0.1	2.4	8.6	-1.4	1.4	2.9	-1.8	-0.7	1.4	1.4	1.5	0.7	1.8
Medication for hormone replacement therapy	0.1	0.1	1.0	-0.0	-0.0	-1.0	0.4	0.1	-0.4	0.0	0.0	-0.0	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	1.6	-0.3	0.3	-1.2	0.7	-0.4	0.4	0.1	0.3	0.3	0.9
Medication: Atenolol	0.1	0.1	0.6	-0.2	0.2	-0.2	0.5	0.4	0.0	0.0	0.2	0.5	0.8
Nervous feelings	0.1	0.2	1.1	-0.2	0.1	0.8	0.1	-0.2	-0.0	0.1	0.2	0.2	1.0
Hearing difficulty/problems with background noise	0.1	0.2	1.3	-0.2	0.5	-0.6	-1.2	-0.1	0.0	0.1	0.3	-0.2	0.4
Medication: Simvastatin	0.1	0.2	0.5	-0.4	0.4	-0.6	0.2	-0.2	0.2	0.5	0.4	0.1	0.7
Pulse rate	0.1	0.2	0.7	-0.4	0.5	0.1	-0.9	0.3	-0.5	0.3	0.5	-0.0	0.7
Exposure to tobacco smoke at home	0.1	0.1	0.2	0.2	-0.4	-0.4	-0.5	-0.4	-0.5	-0.4	-0.2	-0.2	-0.1
Medication for cholesterol, blood pressure or diabetes	0.1	0.2	0.6	-0.6	0.7	0.4	-0.5	0.0	-0.2	0.7	0.5	0.7	0.5
Glaucoma (self-reported)	0.1	0.1	0.6	0.2	-0.0	0.8	0.3	0.1	0.0	-0.2	-0.3	-0.5	-0.5
Leg fat percentage (right)	0.1	0.3	1.5	0.0	0.2	-0.4	0.7	0.1	-0.7	-0.1	-0.1	-0.5	-1.2
Reason for reducing amount of alcohol drunk: Health precaution	0.1	0.1	0.5	0.3	-0.0	0.2	0.3	-0.2	0.7	-0.3	-0.2	-0.6	0.1
Emphysema/chronic bronchitis	0.1	0.2	0.8	0.1	0.2	-0.3	-0.2	0.8	0.4	-0.3	-0.0	0.3	-0.9
Medication: Blood pressure	0.1	0.2	0.7	-0.1	0.1	0.1	0.6	0.5	0.8	-0.0	0.2	0.3	0.6
Medication: Seretide 50 evohaler	0.1	0.1	0.9	0.1	-0.1	-0.9	0.5	-0.3	-0.4	-0.1	-0.1	-0.1	0.0
Suffer from ‘nerves’	0.1	0.2	1.3	-0.3	0.2	-1.1	0.4	-0.4	0.0	0.3	0.2	-0.3	-0.1
Illnesses of father: None of the above (group 1)	0.1	0.2	1.1	0.1	-0.1	-1.0	0.2	0.3	-0.4	-0.3	-0.1	-0.6	-0.4
Mother’s age at death	0.1	0.1	0.6	0.3	-0.3	0.0	0.4	0.7	-0.1	-0.4	-0.3	-0.5	-0.3
Supplements: Fish oil (including cod liver oil)	0.1	0.1	0.5	-0.3	0.3	0.7	0.1	-0.2	0.2	0.5	0.3	0.0	-0.7
Medication: Bendroflumethiazide	0.1	0.2	0.7	0.4	-0.5	-0.2	0.8	0.4	0.4	-0.6	-0.4	0.0	0.2
Leg fat percentage (left)	0.1	0.3	1.1	0.0	0.2	-0.6	1.1	0.1	-0.5	-0.1	-0.1	-0.5	-1.0
Commuting to job workplace: Cycle	0.1	0.2	0.5	-0.3	0.2	0.7	-0.4	0.4	-0.4	0.2	0.4	0.6	-0.2
Alcohol drinker status: Previous	0.1	0.1	0.3	-0.1	0.0	0.2	-0.0	0.2	0.5	0.4	0.1	-0.5	-0.4
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	-0.2
Relative age of first facial hair	0.0	0.1	0.6	-0.0	0.2	0.7	-0.4	0.4	0.1	0.2	0.1	0.3	0.2
Medication: Cholesterol lowering	0.0	0.1	0.3	0.1	-0.2	-0.2	0.4	-0.2	-0.3	-0.2	-0.1	-0.5	0.3
Average weekly red wine intake	0.0	0.0	0.1	0.0	-0.1	0.1	-0.2	0.0	-0.2	-0.3	-0.1	0.3	-0.3

Hub : Genes

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Trait associations