Best TWAS P=3.58e-23 · Best GWAS P=3.43e-25 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | GPR126 | 0.06 | 0.04 | lasso | 4 | 0.04 | 6.1e-04 | -9.8 | 9.9 | 3.6e-23 | -0.98 | 0.02 | 0.96 | TRUE |
| 2 | METSIM | Adipose | GPR126 | 0.05 | 0.01 | blup | 429 | 0.02 | 1.9e-04 | -5.1 | 7.2 | 8.4e-13 | -0.74 | 0.10 | 0.90 | FALSE |
| 3 | NTR | Blood | HIVEP2 | 0.02 | 0.01 | blup | 424 | 0.01 | 2.6e-03 | -3.3 | -5.7 | 1.5e-08 | 0.41 | 0.34 | 0.05 | FALSE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | NMBR | 0.03 | 0.03 | blup | 46 | 0.02 | 3.6e-05 | 4.7 | -5.6 | 1.8e-08 | 0.13 | 0.88 | 0.04 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | VTA1 | 0.03 | 0.02 | blup | 66 | 0.02 | 1.7e-03 | 6.0 | -5.8 | 5.8e-09 | 0.08 | 0.21 | 0.18 | FALSE |
| 6 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | NMBR | 0.09 | 0.01 | blup | 46 | 0.04 | 3.4e-02 | 4.4 | -6.2 | 4.2e-10 | 0.11 | 0.02 | 0.66 | TRUE |