[Hub]/) : Traits : Whole body fat-free mass :

chr8:56,094,665-57,683,880

Best TWAS P=1.61e-30 · Best GWAS P=2.06e-53 conditioned to 1.2e-31

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial RP11-446E9.1 0.07 0.00 lasso 6 0.00 6.6e-01 -7.0 8.3 7.2e-17 -0.71 0.03 0.63 FALSE
2 GTEx Brain Cerebellum RPS20 0.26 0.07 enet 17 0.10 5.4e-04 -10.1 -8.8 1.0e-18 0.64 0.13 0.67 FALSE
3 GTEx Brain Cerebellum RP11-446E9.1 0.15 0.05 lasso 3 0.03 3.7e-02 -6.7 6.5 8.7e-11 -0.54 0.06 0.47 FALSE
4 GTEx Brain Nucleus accumbens basal ganglia RPS20 0.41 0.05 lasso 8 0.13 3.1e-04 -7.3 -6.8 8.8e-12 0.54 0.04 0.41 FALSE
5 GTEx Cells EBV-transformed lymphocytes LYN 0.35 0.07 enet 37 0.17 4.5e-06 11.0 -5.4 6.9e-08 -0.12 0.15 0.05 TRUE
6 GTEx Esophagus Muscularis RPS20 0.12 0.04 lasso 6 0.05 7.2e-04 -10.2 -9.9 3.1e-23 0.81 0.20 0.68 FALSE
7 GTEx Muscle Skeletal RPS20 0.07 0.09 lasso 1 0.07 1.5e-07 -6.6 -6.6 5.0e-11 0.52 0.92 0.08 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic RPS20 0.18 0.03 enet 12 0.07 1.5e-04 -9.7 -11.5 1.6e-30 0.80 0.15 0.46 TRUE
9 GTEx Stomach RP11-446E9.1 0.12 0.08 lasso 4 0.03 1.7e-02 -6.1 6.0 1.7e-09 -0.51 0.26 0.20 FALSE
10 ROSMAP Brain Pre-frontal Cortex RPS20 0.24 0.20 lasso 6 0.23 3.4e-29 -8.3 -7.3 2.2e-13 0.55 1.00 0.00 FALSE
11 ROSMAP Brain Pre-frontal Cortex RP11-446E9.1 0.23 0.32 lasso 7 0.34 2.0e-45 -6.6 7.6 3.5e-14 -0.56 1.00 0.00 FALSE
12 The Cancer Genome Atlas Bladder Urothelial Carcinoma PENK 0.03 0.01 blup 40 0.03 9.1e-04 -4.8 -5.3 1.4e-07 0.00 0.02 0.68 FALSE
13 The Cancer Genome Atlas Colon Adenocarcinoma PENK 0.11 0.13 lasso 2 0.14 2.6e-08 -5.1 -5.3 1.4e-07 0.02 0.01 0.99 FALSE
14 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PENK 0.07 0.06 enet 8 0.08 2.4e-09 -4.6 -5.3 1.2e-07 0.03 0.02 0.97 FALSE
15 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma RPS20 0.04 0.02 blup 29 0.03 4.8e-04 -8.1 -7.4 1.3e-13 0.51 0.03 0.03 FALSE
16 The Cancer Genome Atlas Brain Lower Grade Glioma RPS20 0.33 0.07 enet 8 0.07 1.7e-08 -8.3 -9.5 1.4e-21 0.52 0.96 0.03 FALSE
17 The Cancer Genome Atlas Prostate Adenocarcinoma RPS20 0.04 0.03 lasso 3 0.04 1.3e-04 -8.3 -8.3 8.5e-17 0.60 0.15 0.05 FALSE
18 The Cancer Genome Atlas Thyroid Carcinoma LYN 0.09 0.12 lasso 2 0.12 8.4e-12 -6.1 6.2 6.7e-10 -0.53 1.00 0.00 FALSE