TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Whole body fat-free mass
:
←
→
chr1:109,316,076-110,733,794
Best TWAS P=4.53e-10 · Best GWAS P=3.36e-07 conditioned to 0.682
109.4M
109.6M
109.8M
110M
110.2M
110.4M
110.6M
110.8M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Liver
ATXN7L2
0.39
0.04
lasso
12
0.21
1.3e-06
5.1
6.2
4.5e-10
0.78
0.04
0.88
TRUE
3
The Cancer Genome Atlas
Liver Hepatocellular Carcinoma
MYBPHL
0.09
0.07
blup
46
0.06
5.7e-04
3.0
5.9
3.4e-09
0.78
0.01
0.69
FALSE
5
The Cancer Genome Atlas
Stomach Adenocarcinoma
SORT1
0.04
0.01
blup
60
0.03
4.4e-03
4.7
5.7
1.2e-08
0.73
0.02
0.35
FALSE
1
GTEx
Liver
SYPL2
0.34
0.27
lasso
5
0.30
4.6e-09
4.7
5.7
1.3e-08
0.85
0.04
0.95
FALSE
4
The Cancer Genome Atlas
Ovarian Serous Cystadenocarcinoma
MYBPHL
0.16
0.18
enet
10
0.17
2.3e-11
5.0
5.2
2.1e-07
0.93
0.01
0.99
FALSE