[Hub]/) : Traits : Whole body fat-free mass : ← →

chr14:24,039,559-25,605,046

Best TWAS P=1.28e-14 · Best GWAS P=4e-14 conditioned to 0

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	ADCY4	0.08	0.04	lasso	3	0.03	3.3e-03	5.0	5.3	8.8e-08	0.62	0.20	0.27	FALSE
2	GTEx	Breast Mammary Tissue	LTB4R	0.30	0.18	lasso	4	0.16	2.3e-08	5.2	-5.2	2.3e-07	-0.63	0.74	0.24	FALSE
3	GTEx	Heart Atrial Appendage	ADCY4	0.28	0.14	lasso	4	0.10	2.1e-05	7.0	6.0	2.1e-09	0.48	0.07	0.83	TRUE
4	GTEx	Lung	LTB4R	0.19	0.15	lasso	6	0.12	2.0e-09	5.0	-5.5	3.8e-08	-0.66	0.99	0.01	FALSE
5	GTEx	Muscle Skeletal	CBLN3	0.14	0.13	enet	7	0.13	4.8e-13	4.8	-5.2	2.2e-07	-0.13	1.00	0.00	TRUE
6	GTEx	Spleen	NFATC4	0.45	0.00	enet	24	0.00	2.5e-01	4.7	-6.1	1.2e-09	-0.22	0.07	0.06	TRUE
7	GTEx	Thyroid	ADCY4	0.13	0.13	lasso	6	0.09	1.0e-07	4.3	5.7	1.4e-08	0.51	0.36	0.64	FALSE
8	METSIM	Adipose	ADCY4	0.07	0.03	lasso	5	0.03	2.2e-05	7.2	7.7	1.3e-14	0.71	0.04	0.96	TRUE
9	METSIM	Adipose	LTB4R	0.15	0.07	blup	498	0.07	6.2e-11	5.2	-5.1	2.8e-07	-0.61	0.38	0.62	TRUE
10	METSIM	Adipose	RABGGTA	0.10	0.06	lasso	9	0.08	5.5e-12	5.7	5.3	1.4e-07	0.62	0.99	0.01	TRUE
11	YFS	Blood	KHNYN	0.36	0.20	enet	50	0.29	1.2e-96	4.2	5.2	2.2e-07	0.14	1.00	0.00	TRUE
12	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	ADCY4	0.03	0.01	blup	75	0.03	1.1e-03	4.7	6.0	2.5e-09	0.71	0.05	0.73	FALSE
13	The Cancer Genome Atlas	Colon Adenocarcinoma	ADCY4	0.07	0.02	lasso	4	0.03	4.7e-03	5.0	5.9	4.3e-09	0.70	0.03	0.76	TRUE
14	The Cancer Genome Atlas	Colon Adenocarcinoma	CBLN3	0.24	0.14	enet	8	0.13	4.0e-08	4.8	-5.1	3.0e-07	-0.14	0.50	0.49	FALSE
15	The Cancer Genome Atlas	Brain Lower Grade Glioma	ADCY4	0.06	0.06	lasso	6	0.09	3.0e-10	6.5	7.5	7.5e-14	0.75	0.05	0.95	FALSE
16	The Cancer Genome Atlas	Lung Adenocarcinoma	ADCY4	0.07	0.09	lasso	3	0.08	4.4e-10	5.2	6.5	8.1e-11	0.73	0.84	0.16	FALSE
17	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	LTB4R	0.16	0.05	blup	73	0.08	4.9e-04	3.5	-5.6	2.4e-08	-0.70	0.03	0.57	FALSE
18	The Cancer Genome Atlas	Stomach Adenocarcinoma	LTB4R	0.04	0.01	blup	73	0.01	4.2e-02	6.2	-5.7	1.2e-08	-0.63	0.01	0.45	FALSE
19	The Cancer Genome Atlas	Stomach Adenocarcinoma	LTB4R2	0.04	0.04	lasso	1	0.02	2.5e-02	6.2	-6.2	6.3e-10	-0.70	0.04	0.53	FALSE