Hub : Genes

RABGGTA

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Esophagus Gastroesophageal Junction	0.1910	0.0700	3.9e-03	-0.008	NA	0.001	NA	-0.007	9.5e-01	NA	2.9e-01	NA	6.7e-01
2	GTEx	Esophagus Mucosa	0.1420	0.0480	1.5e-03	0.042	NA	0.050	NA	0.080	8.5e-04	NA	2.7e-04	NA	4.9e-06
3	GTEx	Lung	0.0899	0.0377	6.0e-03	0.058	NA	0.026	NA	0.051	2.9e-05	NA	3.8e-03	NA	8.2e-05
4	METSIM	Adipose	0.0981	0.0253	1.1e-07	0.060	0.061	0.075	0.063	0.080	2.7e-09	1.8e-09	2.3e-11	8.3e-10	5.5e-12
5	NTR	Blood	0.0272	0.0099	7.4e-05	0.018	0.015	0.016	0.015	0.018	1.7e-06	9.6e-06	4.8e-06	9.0e-06	8.9e-07
6	TCGA	Brain Lower Grade Glioma	0.0332	0.0183	3.2e-03	0.028	0.014	0.015	NA	0.022	3.6e-04	9.5e-03	6.4e-03	NA	1.4e-03
7	TCGA	Lung Squamous Cell Carcinoma	0.0697	0.0376	3.2e-03	0.030	0.020	0.016	NA	0.026	2.1e-04	2.1e-03	5.0e-03	NA	5.3e-04
8	TCGA	Stomach Adenocarcinoma	0.0620	0.0350	9.4e-03	0.012	0.016	0.013	NA	0.005	4.1e-02	2.4e-02	3.7e-02	NA	1.4e-01
9	TCGA	Testicular Germ Cell Tumors	0.2640	0.1210	5.0e-03	0.143	0.051	0.152	NA	0.139	9.9e-06	7.0e-03	5.1e-06	NA	1.3e-05
10	TCGA	Thyroid Carcinoma	0.0390	0.0230	7.0e-03	0.004	0.010	0.014	NA	0.011	1.2e-01	3.3e-02	1.4e-02	NA	2.5e-02

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10
Bipolar Disorder (2018)	0.5	0.8	1.7	-0.4	-1.1	-1.2	1.1	0.2	-1.3	-0.7	-0.6	0.0	-0.9
Bipolar Disorder or Schizophrenia	0.3	0.7	2.5	-0.6	-1.0	-0.9	-0.3	1.6	-1.2	0.1	-0.3	1.0	-0.1
Depressed Affect (Nagel 2018)	0.4	0.8	2.6	0.4	1.0	-1.4	0.2	-0.5	-1.6	-0.4	-0.7	0.1	-1.0
Depression (Nagel 2018)	0.4	0.5	2.2	0.6	0.5	-0.0	-1.5	1.0	-0.1	0.6	-0.6	0.7	0.5
Intelligence (Savage-Jansen 2018)	0.3	0.8	2.4	0.3	-0.4	-0.9	0.3	-1.1	-0.8	-0.7	1.5	-0.7	-1.4
Neuroticism (Nagel 2018)	0.2	0.6	2.0	1.4	1.3	-0.4	0.5	-0.4	-0.6	0.6	-0.3	0.8	0.0
Schizophrenia (2018)	0.4	0.9	3.6	-0.5	-0.4	-0.2	-1.3	1.9	-0.5	0.7	0.1	1.3	0.6
Schizophrenia vs Biploar Disorder	2.1	2.8	5.7	0.9	2.4	2.0	-0.2	0.1	1.9	2.0	2.0	2.0	1.0
Worry (Nagel 2018)	0.6	1.2	3.3	1.8	1.4	0.8	0.3	0.5	0.6	1.5	-0.3	1.4	1.0
Alzheimer’s Disease (in mother)	0.3	0.4	1.4	-0.3	-1.1	-0.1	1.2	0.3	0.1	-0.6	0.1	-0.9	0.1
Alzheimer’s Disease (in father)	0.7	0.8	2.2	0.1	0.1	1.1	0.1	0.1	1.1	1.5	0.4	1.4	1.0
Alzheimer’s Disease (including proxy)	0.2	0.3	1.4	-0.5	-1.0	-0.3	1.2	-0.4	-0.3	0.3	0.3	-0.4	0.2
Crohns Disease (2017)	0.7	1.5	2.5	0.4	1.2	1.6	-1.6	0.1	1.6	1.6	0.7	1.4	1.3
Irritable Bowel Disease (IBD)	0.3	0.6	1.5	0.6	1.1	0.3	-1.2	-0.5	0.2	0.7	1.2	0.8	0.4
Ulcerative Colitis (UC)	0.5	0.9	2.3	0.8	0.3	-1.4	-0.4	-1.2	-1.5	-0.6	1.1	-0.5	-1.1
Major Depression (MDD)	1.6	2.0	4.7	0.2	-1.6	-2.0	0.3	0.5	-2.2	-1.5	-1.8	-0.8	-1.4
Reaction Time	0.7	1.4	10.4	3.2	0.5	0.2	-0.4	-1.1	0.2	0.7	0.9	0.8	-0.1
Verbal and Numeric Reasoning (VNR)	1.1	2.7	6.9	-0.5	-0.5	-1.3	1.7	-2.1	-1.1	-1.4	2.6	-1.0	-2.6
Breast Cancer	1.6	3.8	6.9	0.6	1.4	2.1	-1.3	2.1	2.0	2.5	-0.7	2.6	2.6
Ovarian Cancer	0.3	0.3	0.8	0.5	-0.5	0.7	0.1	0.4	0.8	0.5	0.9	0.6	0.5
Prostate Cancer	0.6	0.9	3.0	0.6	0.9	0.5	1.7	-0.6	0.4	0.9	1.2	1.2	0.2
Age at First Birth	0.7	1.0	5.5	-2.4	-1.2	-0.1	-0.2	1.0	0.1	-0.2	-1.2	0.3	0.5
Bipolar Disorder (2011)	0.4	0.3	1.1	0.0	-1.0	-1.1	-0.7	0.9	0.0	0.0	0.0	0.0	0.0
Body Mass Index (BMI) (2010)	0.5	0.6	1.9	0.5	1.0	0.6	1.4	-1.0	0.8	0.2	0.8	-0.5	0.0
Coronary Artery Disease (CAD)	0.3	0.3	1.7	-1.3	-0.9	0.3	-0.4	0.1	0.2	-0.2	0.6	-0.3	-0.3
Crohns Disease (2012)	1.6	2.6	5.3	0.7	1.1	1.8	-2.3	1.6	1.7	2.1	0.9	1.6	1.6
Mean Putamen Volume	0.5	0.6	1.9	-1.4	0.1	-0.9	-0.3	0.1	-1.1	-0.6	-1.0	0.1	-0.5
Fasting Glucose	0.7	0.9	3.1	1.7	0.3	0.6	0.8	-1.0	0.8	0.7	1.6	0.1	0.1
HbA1C	1.0	1.1	4.4	0.8	-2.1	-0.6	-0.3	-0.1	-0.9	-1.1	-0.2	-1.2	-1.4
HDL Cholesterol	1.8	3.0	6.0	2.4	0.6	1.8	-1.2	2.2	1.8	1.9	-0.8	1.3	2.2
LDL Cholesterol	0.9	1.4	3.9	0.8	1.4	2.0	-0.6	0.1	1.9	1.0	1.1	0.5	1.1
Lupus	0.7	1.0	3.7	1.2	0.1	0.1	-0.2	1.5	-0.1	0.3	-1.9	1.3	0.9
Neuroticism (2016)	0.4	0.6	1.5	1.1	0.3	0.5	-0.2	-0.2	0.2	1.2	-0.3	1.2	1.0
Primary Biliary Cirrhosis	0.8	1.1	3.6	0.4	1.4	0.8	0.2	-0.3	0.8	1.3	-0.3	1.4	1.9
Rheumatoid Arthritis	0.5	0.7	3.6	-0.3	0.9	-0.4	0.6	-0.2	-0.4	-1.0	-1.9	-0.7	-0.5
Schizophrenia (2014)	0.2	0.5	1.4	-0.2	-0.0	-0.2	-1.2	1.0	-0.4	0.5	0.3	1.1	0.6
Triglycerides	0.4	0.6	2.1	0.4	-0.2	0.9	-1.5	-0.8	1.1	0.6	0.9	0.2	0.6
Type 2 Diabetes (T2D) (2012)	0.8	1.0	2.7	-1.6	0.2	0.7	-1.4	-0.3	1.0	0.0	-1.5	0.0	1.1
Ulcerative Colitis	0.2	0.2	0.9	-0.1	0.0	-0.8	-0.4	-0.1	-1.0	0.2	0.5	0.5	-0.3
Blood Eosinophil Count	0.1	0.5	2.1	-1.0	0.2	0.6	-1.4	0.2	0.8	0.3	-0.8	0.2	0.4
Blood Platelet Count	0.5	5.6	9.9	-2.5	-2.1	-3.1	0.2	-2.0	-3.1	-3.1	-0.3	-1.9	-3.0
Blood Red Count	0.1	1.4	7.2	-1.1	0.6	1.0	0.1	-1.2	1.1	1.2	2.7	0.0	-0.4
Blood White Count	0.9	6.9	22.6	-4.8	-0.6	-1.5	1.0	-3.2	-0.9	-3.3	-0.2	-4.2	-1.9
Heel T-Score	2.0	15.5	35.2	3.1	2.5	4.5	-5.9	4.4	4.5	3.4	-1.5	3.3	4.3
BMI	0.5	2.7	9.3	-3.1	-1.0	-1.0	0.0	-0.8	-0.7	-2.4	-1.9	-2.0	-1.0
Height	2.6	50.1	134.6	-0.7	-4.2	-10.6	10.4	-4.2	-11.6	-6.0	0.5	-3.3	-7.9
Waist Hip Ratio (WHR)	0.1	0.4	1.1	0.0	-0.8	-0.9	-0.0	0.5	-1.1	-0.2	-0.8	-0.1	-0.8
Systolic Blood Pressure	1.9	9.5	18.7	-2.9	-2.6	-4.1	-0.2	-1.0	-4.0	-4.3	-2.4	-3.9	-2.5
Smoking Status	1.2	3.0	7.2	-1.5	-0.2	-1.6	1.1	-1.4	-1.5	-2.6	0.6	-2.3	-2.7
Allergy or Eczema	0.3	0.8	3.2	0.3	0.7	0.5	-0.7	0.7	0.5	1.0	-0.4	1.8	1.1
Cardiovascular Disease	1.1	3.5	9.5	-2.0	-1.0	-2.2	0.4	-0.3	-2.2	-2.4	-3.1	-1.9	-1.0
Hypothyroidism (self reported)	0.4	0.8	2.4	0.9	1.0	0.5	0.7	0.1	0.4	0.8	-1.4	0.6	1.6
Respiratory disease	0.4	0.8	1.8	0.6	-1.4	-0.9	-0.9	-0.8	-0.6	-1.2	-0.5	-1.0	-0.7
Type 2 Diabetes (T2D) (2018)	0.9	1.6	5.4	-2.3	-0.3	-1.3	1.1	-1.4	-1.2	-1.1	0.5	-1.3	-1.3
Lung FEV1/FVC ratio	0.8	4.3	8.2	-1.3	-2.3	-2.9	0.4	-2.0	-2.8	-2.3	-1.2	-1.7	-2.5
Lung FVC	0.3	1.5	6.4	0.7	0.3	-0.7	0.2	2.5	-1.2	1.2	-0.6	2.0	0.1
Neuroticism	0.4	1.1	4.2	1.1	2.0	-0.4	0.7	-1.0	-0.7	1.0	0.5	1.3	-0.1
Chronotype (morning person)	0.8	1.8	8.8	-1.1	-1.5	-0.2	-0.3	-0.2	0.1	-1.3	-3.0	-2.0	0.3
Hair Pigment	0.1	2.3	6.2	0.4	2.5	1.5	0.0	0.1	1.4	2.0	0.9	2.4	1.4
Tanning	0.1	0.9	2.2	0.6	-0.7	-1.5	0.1	-1.3	-1.5	-0.5	0.8	0.0	-1.3
Hand grip strength (left)	0.4	0.9	2.3	0.8	-1.2	-1.3	0.8	0.9	-1.5	-0.8	-1.0	-0.6	-0.3
Number of treatments/medications taken	1.8	3.3	7.2	-0.3	-2.0	-2.6	0.1	0.6	-2.7	-1.9	-2.5	-1.3	-1.7
Average weekly spirits intake	0.1	0.1	0.4	0.7	-0.1	0.3	-0.1	-0.4	0.3	0.1	0.0	-0.5	0.1
Sensitivity / hurt feelings	0.4	0.7	1.7	1.1	0.5	0.5	0.9	0.3	0.4	1.0	-0.0	1.3	1.1
Frequency of depressed mood in last 2 weeks	0.5	0.7	1.8	-0.7	0.7	-0.6	-1.4	1.0	-0.7	0.2	-1.3	0.8	0.3
Hearing difficulty/problems: Yes	0.1	0.2	1.0	0.5	0.3	0.0	-0.1	1.0	0.1	-0.2	-0.6	-0.1	-0.5
Relative age of first facial hair	5.5	11.2	22.4	1.5	4.0	3.9	-0.8	3.6	3.6	4.2	0.9	4.7	3.5
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	3.5	1.9	-0.1	-0.6	-0.4	0.5	-0.8	0.3	0.5	0.6	-0.9
Ever used hormone-replacement therapy (HRT)	2.9	3.7	7.4	-0.8	-0.5	-2.5	2.1	-1.5	-2.6	-2.0	1.7	-1.3	-2.7
Ever had hysterectomy (womb removed)	0.1	0.1	0.5	0.6	0.7	-0.0	0.0	0.2	-0.3	0.3	-0.4	0.4	-0.2
Systolic blood pressure, automated reading	1.8	5.1	10.1	-2.0	-2.5	-2.6	-1.2	-0.5	-2.4	-3.2	-1.8	-3.1	-1.9
Eye problems/disorders: Diabetes related eye disease	1.2	1.3	3.3	-1.8	0.8	1.6	-1.3	0.7	1.7	0.6	-0.2	0.1	0.9
Angina	0.2	0.3	0.9	0.4	1.0	-0.4	-0.9	-0.6	-0.4	-0.1	0.2	-0.1	0.1
Medication for hormone replacement therapy	0.6	0.6	2.1	0.5	0.6	-0.2	1.4	-0.5	-0.4	0.8	1.5	1.0	0.0
Vitamin and mineral supplements	0.6	0.8	3.8	-0.1	0.2	1.0	-2.0	0.7	1.1	0.4	1.0	-0.0	0.6
Supplements: Zinc	0.5	0.5	2.9	0.5	-0.8	-0.7	1.7	0.0	-0.8	-0.0	-0.1	-0.5	-0.4
Medication: Co-codamol	0.3	0.3	1.4	1.2	0.4	-0.1	0.9	-0.6	-0.1	-0.0	-0.6	0.1	0.4
Medication: Metformin	0.1	0.2	0.7	-0.8	-0.2	0.7	-0.1	-0.1	0.7	0.3	0.3	-0.0	0.3
Diabetes (father)	1.7	2.1	14.0	-3.7	-1.3	-0.9	-0.6	-0.1	-0.8	-0.8	-1.4	-1.0	-0.1
Diabetes (mother)	0.8	1.0	3.9	0.2	-0.8	0.1	-2.0	1.7	-0.1	0.8	0.2	1.3	-0.1
Severe depression (siblings)	0.3	0.3	1.0	-0.2	-0.0	0.4	0.4	-0.9	0.5	0.5	1.0	0.4	0.4
Pack years adult smoking proportion	0.4	0.7	1.5	-0.5	-0.4	-1.1	0.8	-0.4	-1.1	-1.2	0.0	-1.0	-0.6
Impedance of leg (right)	0.4	1.8	4.5	-0.5	0.8	1.6	-2.1	1.1	1.6	1.7	0.7	1.0	1.5
Leg fat-free mass (left)	1.6	8.3	21.9	-0.6	-1.1	-4.0	4.7	-2.2	-4.2	-3.1	-0.5	-1.8	-2.8
Trunk fat percentage	0.4	1.7	4.4	-2.1	-1.1	-1.3	-1.0	-0.9	-1.2	-1.7	-1.0	-1.4	-0.6
Hand grip strength (right)	0.1	0.4	1.9	0.3	0.1	-0.3	0.7	0.6	-0.4	-0.3	-1.4	-0.3	0.9
Townsend deprivation index at recruitment	3.8	5.3	9.2	-2.5	-2.4	-2.4	1.0	-2.1	-2.2	-2.6	0.7	-2.9	-3.0
Current tobacco smoking	1.5	2.5	5.5	-1.4	-0.9	-1.8	1.5	-1.0	-1.7	-1.9	1.1	-1.6	-2.3
Average weekly fortified wine intake	0.7	0.8	4.8	2.2	0.7	0.6	-0.4	-0.2	0.6	0.9	0.7	0.3	0.4
Maternal smoking around birth	0.5	0.7	2.5	1.0	0.3	-0.3	0.3	-0.0	-0.5	0.9	1.2	1.6	-0.9
Fed-up feelings	0.3	0.6	1.3	-0.4	0.8	-1.1	-0.2	-0.6	-1.2	-0.6	-1.0	-0.2	-0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.2	0.2	1.1	-0.3	0.1	0.0	-1.0	0.8	0.2	-0.0	-0.4	-0.2	0.4
Relative age voice broke	2.8	4.3	8.9	1.8	2.1	2.4	-0.3	2.1	2.2	2.6	-0.1	3.0	2.1
Taking other prescription medications	0.6	1.0	3.1	-0.7	-0.9	-1.2	-0.4	0.8	-1.4	-0.4	-1.8	0.6	-0.5
Age when periods started (menarche)	1.3	3.2	5.6	2.3	0.9	2.2	-0.4	2.4	2.2	1.8	-1.2	1.4	2.0
Bilateral oophorectomy (both ovaries removed)	0.5	0.6	2.1	-0.6	0.3	-0.9	1.0	-1.5	-1.0	-0.4	0.3	0.2	-0.5
Heel bone mineral density (BMD) T-score, automated (left)	2.7	6.2	9.5	1.8	2.5	3.0	-2.7	2.2	3.0	2.5	-1.3	2.3	3.1
Tinnitus: Yes, but not now, but have in the past	2.4	2.6	5.1	-1.0	-1.0	-2.3	1.4	-1.7	-2.2	-2.0	0.3	-1.5	-1.5
Qualifications: CSEs or equivalent	2.6	3.4	8.4	1.1	2.0	2.1	0.0	0.6	2.0	2.5	0.2	2.9	2.2
Serious illness, injury or assault to yourself	1.4	1.7	3.8	-1.3	-1.3	-1.9	0.5	-1.1	-1.9	-1.0	0.4	-0.9	-1.7
High blood pressure	1.5	4.3	8.6	-1.6	-1.5	-2.8	0.5	-0.5	-2.7	-2.9	-2.3	-2.2	-1.8
Hayfever, allergic rhinitis or eczema	0.1	0.1	0.6	0.2	0.1	-0.5	-0.3	-0.3	-0.5	0.0	-0.4	0.8	0.3
Multivitamins +/- minerals	0.4	0.5	2.0	0.7	0.4	-0.1	1.4	0.0	-0.3	0.7	-0.9	0.8	0.4
Stomach or abdominal pain in last month	2.0	2.5	4.9	1.2	-1.1	-2.0	0.3	-1.5	-1.9	-2.0	-0.2	-1.9	-2.2
Supplements: Glucosamine	0.2	0.3	1.1	0.1	-0.3	-0.8	0.6	0.6	-1.1	-0.0	-0.6	0.4	-0.1
Diverticular disease/diverticulitis (self-reported)	1.3	1.5	2.6	-0.9	-1.4	-1.4	0.9	-1.4	-1.5	-0.8	1.6	-0.4	-1.3
Medication: Atenolol	2.3	2.9	7.1	-2.2	-1.9	-1.6	-1.2	1.6	-1.5	-1.6	-2.7	-1.5	-0.3
Medication: Levothyroxine sodium	0.2	0.3	1.3	-0.0	0.4	0.0	0.7	-0.2	0.1	-0.7	-1.1	-0.6	0.4
Sitting height	0.9	6.2	22.2	1.3	0.2	-3.3	4.7	-1.4	-3.8	-1.7	1.2	-0.6	-2.3
Chronic bronchitis/emphysema (father)	0.5	0.6	3.4	-0.4	0.4	-0.3	0.5	-0.9	-0.5	0.5	1.8	0.6	-0.7
High blood pressure (mother)	0.3	0.4	1.2	-1.1	0.5	-0.7	0.3	0.7	-0.9	-0.2	-0.7	0.6	0.2
Body mass index (BMI)	0.2	1.0	3.8	-2.0	-0.4	-0.4	-0.7	-0.4	-0.2	-1.3	-1.4	-0.9	-0.1
Impedance of leg (left)	0.5	2.4	6.7	0.2	0.6	1.8	-2.6	1.4	1.8	1.8	0.3	1.2	1.9
Leg predicted mass (left)	1.5	8.2	21.7	-0.6	-1.1	-4.0	4.7	-2.2	-4.2	-3.0	-0.5	-1.8	-2.8
Trunk fat mass	0.8	3.6	7.4	-2.2	-1.6	-2.5	0.4	-1.3	-2.4	-2.7	-1.3	-2.0	-1.5
Waist circumference	1.1	4.1	8.5	-2.3	-1.3	-2.9	0.6	-1.0	-2.9	-2.6	-1.2	-1.5	-2.1
Number of incorrect matches in round	0.2	0.4	1.0	-0.3	-0.2	1.0	-0.2	0.7	1.0	0.6	0.4	0.5	0.7
Past tobacco smoking	0.6	1.1	2.0	1.2	-1.0	1.0	-0.0	1.1	1.0	1.4	-0.6	0.9	1.4
Alcohol usually taken with meals	0.4	0.7	2.2	-0.7	-0.7	-0.4	0.4	-0.7	-0.2	-1.2	0.8	-1.5	-0.6
Nervous feelings	1.5	2.7	5.9	2.2	0.9	1.7	-1.5	1.2	1.5	2.4	0.0	2.0	1.8
Frequency of tenseness / restlessness in last 2 weeks	0.2	0.3	0.8	0.9	0.6	-0.0	0.2	0.6	-0.1	0.5	-0.3	0.9	0.8
Hearing difficulty/problems with background noise	0.9	1.5	7.0	-0.2	-0.5	0.2	-1.7	2.7	0.1	0.2	-2.1	0.6	0.6
Hair/balding pattern: Pattern 2	0.4	0.5	3.2	1.8	0.9	0.6	-0.0	0.1	0.5	0.5	0.1	0.5	0.2
Had menopause	0.5	0.6	1.7	-0.4	-0.6	-0.7	-1.3	0.7	-0.7	-0.8	-0.8	-0.8	-0.8
Had other major operations	1.5	1.8	4.6	-1.7	1.6	-0.4	2.2	-0.7	-0.7	0.5	1.8	1.7	-0.3
Forced vital capacity (FVC)	0.7	2.8	9.9	0.4	0.8	-2.2	3.2	0.1	-2.8	0.3	0.5	1.6	-1.3
Heel bone mineral density (BMD) T-score, automated (right)	2.6	6.0	9.2	2.2	1.9	3.0	-3.0	2.2	3.0	2.4	-0.9	2.0	3.0
Ever unenthusiastic/disinterested for a whole week	1.7	2.1	4.2	-0.8	-0.5	-1.8	-0.1	-0.9	-1.7	-2.1	-1.7	-1.6	-1.8
Qualifications: None of the above	0.8	1.7	3.9	0.7	-2.0	-1.4	-1.3	0.5	-1.5	-1.1	-1.6	-0.7	-1.4
Financial difficulties in last 2 years	1.5	2.0	6.4	2.5	1.0	0.8	-0.9	1.7	0.5	1.6	-0.3	1.6	1.5
Mouth/teeth dental problems	2.0	3.1	6.8	0.9	-1.6	-2.1	2.6	-1.8	-2.2	-0.9	1.2	-0.3	-2.5
Heart attack	0.6	0.8	2.2	-0.5	-0.7	-0.8	-0.8	-0.6	-0.6	-1.3	-1.5	-1.2	-0.2
Allergy	0.1	0.3	1.0	-0.9	-0.1	0.3	1.0	0.4	0.2	-0.0	0.1	-0.7	-0.4
Pain all over the body in last month	0.4	0.4	1.2	-0.9	-0.6	-0.8	-0.8	0.1	-1.1	0.5	-0.5	0.2	-0.3
Diabetes (self-reported)	1.1	1.7	4.1	-2.0	-1.1	-1.4	1.3	-1.4	-1.3	-1.1	0.3	-1.2	-1.3
Hayfever/allergic rhinitis (self-reported)	0.1	0.1	0.5	0.4	0.4	-0.2	-0.7	0.0	-0.2	-0.1	-0.1	0.7	0.3
Medication: Ramipril	1.6	2.0	4.4	-2.1	-0.3	-1.3	-0.3	-0.9	-1.1	-1.9	-2.1	-1.9	-0.1
Medication: Simvastatin	1.4	2.0	5.9	-2.4	-0.7	-1.5	-0.8	0.6	-1.6	-1.4	-2.4	-0.3	-0.6
Fluid intelligence score	0.2	0.4	0.8	0.1	-0.9	-0.7	0.5	-0.7	-0.7	-0.0	0.8	0.2	-0.7
Illnesses of siblings	0.6	0.9	3.5	1.9	0.5	1.0	0.3	0.4	1.0	1.0	0.7	0.6	1.0
Neuroticism score	0.1	0.3	0.7	0.7	0.8	-0.4	0.1	-0.5	-0.7	0.6	-0.1	0.7	0.1
Weight	1.2	5.8	12.4	-1.9	-1.4	-3.4	2.6	-1.7	-3.5	-3.0	-1.1	-1.9	-2.2
Impedance of arm (right)	0.1	0.6	2.0	0.5	-0.6	0.2	-1.1	0.4	0.2	1.1	1.4	0.3	0.5
Arm fat percentage (right)	0.5	1.8	5.9	-2.4	-1.4	-0.9	-1.6	-0.5	-0.7	-1.6	-1.4	-1.4	-0.3
Trunk fat-free mass	1.9	10.7	28.5	-0.5	-1.1	-4.6	5.3	-2.1	-4.9	-3.5	-1.0	-1.9	-3.2
Hip circumference	1.1	4.7	11.3	-3.4	-1.3	-2.7	1.0	-1.2	-2.6	-3.0	-0.8	-1.9	-2.0
Time employed in main current job	0.9	1.0	2.8	-0.5	-1.0	-1.0	-0.7	0.8	-1.0	-1.0	-1.7	-1.1	-1.0
Alcohol intake versus 10 years previously	0.8	1.2	3.5	-0.1	-0.2	-1.2	0.9	-1.9	-1.3	-0.5	1.3	-0.9	-1.4
Father’s age at death	0.4	0.6	1.2	1.0	-1.1	-0.6	0.2	-0.1	-0.6	-1.0	0.6	-1.0	-0.8
Worrier / anxious feelings	0.1	0.2	1.0	1.0	0.0	-0.4	0.1	0.2	-0.5	-0.0	-0.7	0.4	0.4
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.3	4.0	1.5	-0.8	-1.8	0.4	0.5	-2.0	-0.6	-0.9	0.5	-0.8
Falls in the last year	1.2	1.6	4.3	2.0	0.4	0.3	-1.2	2.1	0.1	1.1	-1.1	2.0	0.3
Hair/balding pattern: Pattern 3	0.2	0.3	1.5	0.7	-0.5	-0.5	0.0	-1.2	-0.5	-0.0	-0.1	-0.3	-0.4
Number of live births	0.8	1.1	2.4	1.1	0.7	0.8	-0.8	1.1	0.7	1.6	-0.8	1.6	1.0
Forced expiratory volume in 1-second (FEV1)	0.8	2.8	9.1	0.2	0.5	-2.4	2.9	-0.3	-3.0	0.3	-0.0	1.5	-1.4
Pulse rate	0.7	1.2	2.2	0.8	1.5	1.1	0.8	-1.3	1.2	1.1	1.3	0.8	0.6
Happiness	0.8	1.0	4.4	2.1	0.6	0.1	-0.5	1.2	-0.3	0.8	-0.8	1.0	1.1
Noisy workplace	0.2	0.3	0.9	0.5	0.0	-0.4	-0.8	0.5	-0.3	-0.5	-0.9	-0.3	0.2
Qualifications: A levels/AS levels or equivalent	0.2	0.4	1.1	-0.9	-0.8	-0.3	0.2	-0.1	-0.1	-1.0	0.6	-1.0	-0.6
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	2.3	0.9	-1.1	-0.5	-0.1	1.5	-0.7	0.4	0.4	0.4	-0.7
Mouth/teeth dental problems: Dentures	1.6	2.7	10.1	-3.2	-0.2	-1.1	0.6	-1.8	-0.9	-2.2	0.0	-2.2	-1.3
Asthma	0.3	0.6	1.6	0.6	-1.2	-0.6	-1.3	-0.2	-0.3	-1.0	-0.5	-0.7	-0.5
Medication: Ibuprofen (e.g. Nurofen)	1.4	1.8	6.0	-0.3	-0.2	-1.4	1.6	-1.0	-1.6	-0.4	2.4	-0.1	-1.9
Medication: Cholesterol lowering	1.0	1.6	5.2	-1.3	-0.5	-1.3	-0.7	-0.9	-1.2	-1.6	-2.3	-1.1	-0.5
Depression (self-reported)	0.7	0.9	4.0	-0.1	-0.8	-0.9	0.4	1.1	-1.2	0.2	-2.0	0.7	-0.4
Medication: Lansoprazole	0.2	0.2	1.0	-0.7	-0.0	0.3	1.0	-0.1	0.4	-0.1	-0.1	0.1	0.0
Prospective memory result	0.5	0.6	3.2	0.5	0.7	0.3	0.8	-0.6	0.4	-0.1	1.8	-0.1	-0.7
Lung cancer (father)	0.9	1.1	4.1	-1.2	2.0	-0.1	2.0	-0.8	-0.2	-0.2	0.2	0.4	-0.8
Illnesses of mother	0.6	0.7	2.0	1.3	0.4	1.2	-0.9	0.0	1.4	0.6	-0.2	0.4	0.6
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.5	9.4	0.1	0.6	-2.1	3.1	-0.2	-2.7	0.4	0.0	1.5	-1.1
Pulse wave Arterial Stiffness index	1.1	1.3	3.4	-0.6	-0.8	-1.7	1.7	-0.6	-1.9	-0.6	-0.0	-0.8	-1.2
Impedance of arm (left)	0.2	0.8	2.2	0.7	-0.3	0.5	-1.5	0.7	0.5	1.2	1.4	0.4	0.7
Arm fat mass (right)	0.7	2.9	6.1	-2.2	-1.4	-2.0	0.2	-1.1	-1.8	-2.5	-1.5	-1.9	-1.1
Trunk predicted mass	1.8	10.3	28.5	-0.5	-1.1	-4.5	5.3	-2.0	-4.8	-3.4	-1.0	-1.8	-3.1
Standing height	2.1	20.5	52.6	0.0	-2.0	-6.7	7.3	-2.8	-7.2	-4.1	0.4	-2.3	-4.6
Length of working week for main job	0.9	1.0	3.6	1.6	0.3	0.1	1.6	-0.6	-0.1	0.9	1.9	0.2	-0.3
Exposure to tobacco smoke at home	0.5	0.5	2.6	0.9	-1.0	-0.2	0.6	-0.2	-0.4	0.5	1.6	0.4	-0.2
Breastfed as a baby	0.9	1.1	2.9	0.9	-0.1	1.5	-1.0	1.3	1.7	0.7	-0.4	0.9	0.8
Tense / ‘highly strung’	0.8	1.3	2.2	1.4	1.3	1.1	0.9	-0.3	1.0	1.5	1.1	1.3	1.0
Seen doctor (GP) for nerves, anxiety, tension or depression	0.3	0.4	1.2	0.5	-0.0	-0.2	0.0	1.0	-0.5	0.6	-1.1	0.9	0.5
Hair/balding pattern: Pattern 4	1.2	3.0	5.7	0.7	1.8	2.3	0.5	0.5	2.2	2.4	1.5	2.2	1.7
Birth weight of first child	0.4	0.8	2.9	0.3	1.7	-0.5	0.0	1.1	-0.8	0.5	0.1	1.7	-0.1
Peak expiratory flow (PEF)	0.5	1.2	4.6	-0.4	-0.4	-1.8	1.1	0.2	-2.1	-0.3	-1.5	0.2	-0.5
Pulse wave reflection index	0.6	0.7	1.7	-0.6	-1.3	-0.9	0.6	0.1	-1.0	-0.4	0.7	-1.0	-1.0
Ever highly irritable/argumentative for 2 days	0.4	0.5	1.3	-0.6	1.1	0.4	-0.7	0.8	0.3	0.2	-1.0	0.6	0.7
Loud music exposure frequency	0.5	0.6	2.0	1.4	0.2	-0.2	0.5	-1.1	-0.2	0.2	1.4	-0.2	-0.4
Qualifications: O levels/GCSEs or equivalent	0.6	1.0	4.5	-1.1	0.4	-0.3	0.9	-1.2	-0.3	-0.6	2.1	-0.3	-0.9
Mouth/teeth dental problems: Bleeding gums	2.9	3.8	6.8	-0.6	2.6	2.5	-2.0	1.6	2.6	1.5	-1.0	1.1	2.6
Blood clot in the leg (DVT)	0.6	0.8	5.4	0.2	0.7	0.6	0.3	-0.5	0.6	0.4	2.3	0.3	-0.6
Medication: Paracetamol	0.2	0.3	0.9	0.1	-0.4	-0.3	-0.0	1.0	-0.3	0.0	-0.8	0.7	-0.3
Headache pain in last month	0.8	1.4	3.6	1.8	-0.6	-1.7	0.6	0.1	-1.9	-0.9	-1.2	-0.2	-0.9
Medication for cholesterol, blood pressure or diabetes	3.1	5.1	15.8	1.3	1.5	2.7	0.7	0.4	2.5	3.2	4.0	2.5	0.9
Glaucoma (self-reported)	1.0	1.2	3.3	-0.1	1.8	0.7	1.2	0.5	0.5	1.4	1.0	1.8	0.8
Gout (self-reported)	6.0	8.2	14.1	-2.4	-3.3	-3.5	-0.6	-1.2	-3.3	-3.8	-2.9	-3.6	-2.3
Hypothyroidism/myxoedema (self-reported)	0.4	0.8	2.5	0.8	1.6	0.7	1.0	-0.7	0.6	0.7	-0.7	0.5	1.2
Medication: Amlodipine	0.2	0.2	0.8	0.0	-0.3	-0.2	-0.9	0.7	-0.1	-0.4	-0.9	-0.2	-0.2
Medication: Ventolin 100micrograms inhaler	0.5	0.7	2.6	0.7	-0.6	-0.2	-0.6	0.2	0.0	-1.4	-1.6	-1.0	0.2
Birth weight	0.5	1.1	3.1	0.1	-0.9	-1.3	0.8	0.5	-1.4	-1.4	-1.8	-0.8	-0.3
Chronic bronchitis/emphysema (mother)	1.6	1.9	6.2	0.5	-2.5	-1.7	-1.6	-0.4	-1.7	-0.7	-1.3	-1.0	-1.2
High blood pressure (siblings)	2.6	3.8	7.2	-0.7	-1.7	-2.7	2.1	-1.1	-2.7	-2.4	0.1	-1.8	-2.4
Forced vital capacity (FVC), Best measure	0.7	2.7	11.1	0.6	0.8	-1.9	3.3	0.4	-2.5	0.6	0.3	1.7	-1.1
Body fat percentage	0.4	1.6	6.0	-2.5	-1.1	-0.9	-1.3	-0.7	-0.8	-1.5	-1.2	-1.1	-0.3
Leg fat percentage (right)	0.5	1.8	10.0	-3.2	-0.5	-0.1	-2.0	-0.1	0.1	-1.1	-1.2	-0.9	0.1
Arm fat-free mass (right)	1.3	6.9	19.8	-0.6	-0.5	-3.6	4.4	-1.9	-3.9	-2.9	-1.0	-1.4	-2.4
Exposure to tobacco smoke outside home	0.4	0.6	1.9	0.4	1.0	0.4	1.4	-0.4	0.3	0.5	-0.6	0.6	1.2
Comparative body size at age 10	0.6	1.5	6.7	-2.6	0.7	0.8	-0.7	0.8	1.1	-0.9	-1.8	-0.9	0.3
Number of full brothers	0.8	1.0	2.5	0.7	0.0	-1.4	0.8	-1.3	-1.6	-0.7	0.5	0.0	-1.3
Worry too long after embarrassment	0.6	1.0	3.2	-0.9	-0.1	-1.1	1.1	-1.8	-1.1	-0.6	1.1	-0.5	-0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.6	0.8	1.7	-1.1	-0.1	-1.2	1.2	-1.3	-1.2	-0.4	0.2	0.2	-0.9
Wheeze or whistling in the chest in last year	0.7	1.3	4.2	-0.4	-1.0	-1.4	-0.9	0.7	-1.2	-1.5	-2.0	-0.4	-0.2
Number of children fathered	0.5	0.6	1.5	-0.8	0.5	1.1	0.0	0.0	1.2	0.3	0.9	0.8	0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	2.1	0.2	-0.4	0.1	-1.4	0.6	0.2	-0.3	-0.8	-0.5	0.3
Age at first live birth	2.2	3.9	10.0	-2.0	0.2	1.4	-2.8	2.8	1.4	0.5	-3.2	0.4	2.3
Pulse wave peak to peak time	0.4	0.5	1.3	0.4	0.5	1.0	-1.1	0.3	1.2	0.0	-0.0	0.4	0.7
Health satisfaction	1.0	1.3	9.0	3.0	0.4	-0.7	0.2	-0.4	-0.9	0.2	1.4	0.3	-0.5
Shortness of breath walking on level ground	2.1	2.6	5.6	2.4	-0.5	-1.4	0.9	-1.8	-1.1	-2.1	0.2	-2.3	-1.6
Qualifications: College or University degree	0.1	0.4	0.9	-0.8	-0.6	-0.5	0.8	-0.9	-0.5	-0.4	0.8	-0.2	-0.4
Eye problems/disorders: None of the above	0.3	0.4	1.2	0.9	-0.5	-1.0	0.1	-0.7	-1.1	0.1	0.3	0.1	0.1
Mouth/teeth dental problems: Loose teeth	1.0	1.2	4.9	-2.2	0.4	0.9	-1.1	0.7	1.1	-0.5	-1.4	-0.9	0.7
Emphysema/chronic bronchitis	0.7	0.8	2.1	0.0	-0.2	-1.0	0.1	-0.9	-0.8	-1.4	0.0	-1.4	-0.9
Medication for pain relief, constipation, heartburn	0.9	1.6	4.8	0.1	0.9	1.9	-0.6	0.3	1.9	1.4	-0.4	0.9	2.2
Neck or shoulder pain in last month	0.4	0.5	3.0	0.7	0.7	-0.4	0.5	0.3	-0.6	0.6	-0.4	1.7	0.1
Medication: Blood pressure	4.0	7.1	14.7	-1.4	-1.9	-3.4	-0.6	-0.9	-3.3	-3.8	-3.6	-3.5	-1.6
Angina (self-reported)	0.2	0.3	0.7	0.0	0.9	-0.6	-0.8	-0.8	-0.6	-0.3	0.1	-0.3	-0.1
Migraine (self-reported)	2.8	3.5	8.2	-0.9	-2.0	-2.7	1.8	-1.4	-2.9	-1.4	1.2	-0.6	-2.4
Medication: Ibuprofen	2.0	2.3	7.3	-0.2	-0.6	-1.7	1.6	-1.3	-1.9	-0.7	2.7	-0.3	-2.2
Medication: Allopurinol	4.2	5.6	10.8	-1.8	-2.3	-3.0	0.1	-1.3	-2.8	-3.3	-2.2	-3.0	-1.9
Medication: Omeprazole	1.3	1.6	4.1	0.7	0.0	-1.9	1.3	-0.7	-2.0	-1.0	0.7	-0.8	-1.9
Medication: Seretide 50 evohaler	0.6	0.7	1.7	-1.1	-1.0	-0.6	0.4	-0.7	-0.3	-1.3	-0.7	-1.2	-0.6
Mean time to correctly identify matches	0.6	1.2	6.9	2.6	0.4	0.3	-1.0	-1.1	0.3	0.7	0.7	1.1	0.3
Heart disease (mother)	0.2	0.2	0.5	-0.2	0.2	-0.7	-0.2	-0.3	-0.7	-0.5	-0.6	0.1	-0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.2	1.4	6.2	1.5	0.1	0.9	-2.5	1.1	0.9	0.8	0.0	0.9	1.2
Whole body fat mass	0.7	3.1	6.2	-2.2	-1.4	-2.2	0.2	-1.3	-2.1	-2.5	-1.3	-1.9	-1.3
Leg fat mass (right)	0.5	2.1	6.9	-2.6	-0.8	-1.4	0.1	-0.8	-1.3	-2.1	-1.3	-1.5	-0.7
Arm predicted mass (right)	1.3	6.4	19.0	-0.7	-0.3	-3.5	4.4	-1.8	-3.7	-2.8	-0.9	-1.2	-2.3
Pulse rate, automated reading	0.2	0.5	2.0	-0.0	0.8	0.8	0.1	-1.4	0.8	0.7	0.6	0.4	0.5
Alcohol intake frequency.	0.3	0.7	1.3	1.0	-1.1	-0.8	-0.1	-0.3	-1.0	0.7	0.7	1.1	-0.6
Comparative height size at age 10	5.2	28.4	60.2	-2.5	-4.6	-7.5	5.6	-3.9	-7.8	-5.9	0.6	-4.5	-6.2
Number of full sisters	0.4	0.4	1.4	0.7	0.1	0.5	-1.2	0.6	0.5	0.5	-0.5	0.7	0.8
Suffer from ‘nerves’	0.4	0.7	3.0	1.7	0.6	0.7	0.6	0.6	0.7	0.9	0.2	0.4	0.8
Overall health rating	0.4	0.9	3.2	0.5	-0.1	-1.7	-0.4	-0.3	-1.8	-0.9	0.2	0.2	-1.4
Chest pain or discomfort	0.8	1.1	3.8	0.4	-0.5	-1.7	1.2	-1.3	-1.9	-0.3	0.2	0.3	-0.9
Had major operations	0.9	1.0	3.2	1.2	0.9	0.7	0.2	0.3	0.5	1.8	1.0	1.5	0.8
Age at last live birth	1.1	1.7	4.4	-1.0	1.0	1.0	-1.5	1.9	1.0	0.3	-2.1	0.3	1.5
Family relationship satisfaction	0.3	0.4	1.1	0.7	0.0	0.3	0.2	0.7	-0.0	1.0	0.8	1.0	0.6
Leg pain on walking	0.6	0.8	1.9	-0.5	0.2	0.7	-1.3	1.1	1.0	-0.3	-1.4	-0.6	0.7
Qualifications: NVQ or HND or HNC or equivalent	0.2	0.3	1.8	0.2	0.4	0.2	1.4	0.4	0.1	0.4	0.2	0.5	0.3
Commuting to job workplace: Car/motor vehicle	1.1	1.3	2.9	0.9	1.3	1.6	-0.6	-0.3	1.7	1.3	0.3	1.0	1.4
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	1.6	-1.3	-0.4	0.5	0.3	-0.6	0.7	-0.6	-0.6	-0.6	0.4
Medication: Aspirin	0.5	0.7	2.2	-1.1	0.7	0.1	-1.4	0.7	0.2	-0.4	-1.5	0.1	0.3
Supplements: Vitamin C	0.2	0.3	1.4	1.2	1.0	0.2	0.5	-0.1	0.2	0.0	-0.5	0.1	0.0
Knee pain experienced in last month	0.4	0.7	3.1	-0.8	0.9	0.2	-0.6	0.8	0.2	0.4	-1.8	0.8	0.5
Hypertension (Self-reported)	1.4	3.8	7.4	-1.6	-1.4	-2.7	0.6	-0.4	-2.6	-2.7	-2.2	-2.0	-1.7
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.2	5.9	-0.3	0.4	-1.2	2.4	-0.1	-1.5	-0.2	0.7	0.4	-1.2
Illnesses of father: Heart disease	0.8	1.1	3.0	1.2	-0.5	0.9	-0.8	1.7	0.9	1.0	-0.5	1.4	1.2
Illnesses of siblings: Diabetes	0.9	1.1	2.6	-0.6	-0.8	-1.6	-0.4	-0.5	-1.6	-1.3	-0.6	-1.1	-1.3
Smoking status: Previous	0.3	0.4	1.9	-0.1	1.4	-0.1	-1.3	-0.5	-0.2	-0.3	-0.2	-0.0	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.9	1.8	10.6	-0.6	-0.9	-1.4	3.3	-0.3	-1.4	-1.0	0.3	-0.5	-1.0
Whole body fat-free mass	1.7	10.0	27.8	-0.4	-1.1	-4.4	5.3	-2.2	-4.7	-3.3	-0.8	-1.8	-3.1
Leg fat-free mass (right)	1.5	8.1	23.0	-0.2	-1.2	-3.9	4.8	-2.2	-4.1	-3.0	-0.6	-1.7	-2.7
Arm fat percentage (left)	0.3	1.4	4.9	-2.2	-1.0	-0.5	-1.8	-0.3	-0.3	-1.3	-1.2	-1.1	-0.0
Average weekly red wine intake	0.8	1.2	6.4	-1.1	-0.2	-0.1	-1.6	2.5	-0.1	-0.5	-1.2	-0.4	0.2
Handedness (chirality/laterality): Left-handed	0.5	0.6	2.9	1.3	-1.7	-0.1	-0.2	0.4	0.0	-0.1	-0.5	-0.7	0.2
Mood swings	0.2	0.4	1.8	0.3	0.8	0.4	-0.6	0.4	0.2	1.0	-0.3	1.3	0.6
Loneliness, isolation	0.5	0.7	2.8	0.1	-0.2	-0.9	0.1	0.1	-0.8	-1.1	-0.6	-1.7	-0.9
Long-standing illness, disability or infirmity	0.7	1.0	3.0	0.1	0.5	-1.6	1.2	-0.4	-1.7	-0.9	0.1	-0.1	-1.5
Ever had bowel cancer screening	0.3	0.3	1.6	0.3	0.3	0.1	1.3	-0.1	0.1	-0.4	1.0	0.1	-0.3
Diabetes diagnosed by doctor	1.0	1.7	4.0	-1.9	-0.5	-1.2	1.5	-2.0	-1.1	-1.0	0.5	-1.2	-1.3
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.5	4.1	-0.3	2.0	1.5	-0.5	-0.1	1.7	0.8	1.8	0.7	0.8
Friendships satisfaction	0.3	0.4	2.4	0.0	-0.1	0.1	-1.5	0.1	0.1	-0.4	-0.8	-0.4	0.6
Qualifications: nursing, teaching	0.3	0.4	1.5	-0.7	0.3	0.3	1.2	-0.5	0.4	-0.4	1.2	-0.1	-0.2
Commuting to job workplace: Walk	0.3	0.3	1.5	-1.2	-0.2	0.2	-0.2	1.0	0.1	0.5	-0.2	0.1	0.5
Eye problems/disorders: Cataract	1.5	1.7	4.6	-2.1	-0.2	1.6	-1.4	1.8	1.8	0.3	-1.0	0.3	0.9
Mouth/teeth dental problems: Mouth ulcers	5.0	7.9	14.5	3.7	2.3	3.2	-2.3	2.5	3.3	2.6	-1.3	2.2	3.8
Medication for cholesterol	0.7	1.0	3.2	1.4	0.2	1.2	-1.8	0.4	1.2	0.9	0.6	0.6	0.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	2.1	-0.7	0.1	0.6	-0.2	-1.4	0.9	-0.6	0.6	-1.4	0.1
Back pain experienced in last month	0.5	0.7	2.2	0.3	1.3	-0.2	0.3	1.0	-0.4	1.0	-0.9	1.5	0.4
Mineral and other dietary supplements	1.0	1.4	5.6	-1.3	0.1	-0.6	0.5	-1.4	-0.4	-1.0	2.4	-0.9	-1.3
Breast cancer (self-reported)	0.1	0.2	0.5	0.7	0.6	-0.4	0.1	0.4	-0.4	-0.2	0.0	-0.2	-0.3
Asthma (self-reported)	0.4	0.7	1.7	0.4	-1.3	-0.8	-1.2	-0.2	-0.5	-1.1	-0.7	-0.8	-0.6
Osteoporosis (self-reported)	1.0	1.3	3.5	0.1	-1.8	-1.2	0.2	-0.7	-1.1	-1.0	0.5	-1.3	-1.9
Osteoarthritis (self-reported)	0.3	0.4	0.9	-0.8	0.5	-0.9	-0.0	-0.5	-0.9	-0.6	-0.8	0.1	-0.4
Medication: Aspirin	0.4	0.6	1.6	-1.2	0.5	-0.4	-1.3	0.7	-0.3	-0.6	-1.1	0.0	-0.2
Medication: Gliclazide	0.4	0.5	2.1	-1.5	-0.4	0.2	-1.2	0.5	0.3	-0.1	-0.7	0.3	0.1
Illnesses of father: None of the above (group 1)	1.2	1.5	9.8	-0.8	3.1	1.0	0.5	-0.2	1.1	0.8	0.5	0.8	0.5
Smoking status: Current	1.7	2.6	6.2	-1.7	-0.6	-1.7	1.7	-1.1	-1.7	-1.8	1.3	-1.4	-2.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.2	2.6	0.5	1.1	0.0	-1.3	1.1	-0.2	1.4	-1.4	1.6	0.9
Whole body water mass	1.8	10.0	27.5	-0.4	-1.1	-4.4	5.2	-2.2	-4.7	-3.4	-0.8	-1.8	-3.1
Leg predicted mass (right)	1.5	8.3	23.0	-0.2	-1.3	-4.0	4.8	-2.2	-4.2	-3.0	-0.5	-1.8	-2.7
Arm fat mass (left)	0.6	2.3	4.9	-2.2	-1.1	-1.7	0.0	-1.0	-1.6	-2.2	-1.4	-1.7	-0.9
Number of self-reported non-cancer illnesses	4.3	7.4	16.0	-2.7	-2.6	-4.0	0.6	-1.4	-4.0	-3.3	-1.7	-2.1	-2.9
Average weekly champagne plus white wine intake	1.4	2.0	4.8	-0.3	-1.2	-2.1	0.7	-0.8	-2.2	-1.6	-1.1	-1.4	-1.4
Miserableness	0.9	1.6	5.3	-1.3	-0.7	-2.1	-0.0	0.0	-2.3	-1.1	-0.6	-0.2	-1.5
Guilty feelings	0.3	0.5	2.0	-0.4	1.4	-0.8	0.5	-0.7	-1.0	0.1	-0.9	0.0	-0.0
Wears glasses or contact lenses	1.0	1.2	2.4	-1.0	-1.5	-1.1	0.8	-0.5	-0.9	-1.5	-0.6	-1.3	-1.1
Ever taken oral contraceptive pill	0.4	0.5	2.6	-1.6	0.3	0.6	-0.2	0.4	0.8	-0.2	-0.3	0.7	0.6
Hearing aid user	1.4	1.6	4.2	-1.1	-0.5	-1.4	0.4	-0.4	-1.3	-2.1	-0.7	-2.0	-1.4
Mother’s age at death	1.7	2.1	4.0	1.1	1.6	1.0	-1.3	1.5	0.8	1.5	-2.0	1.6	1.7
Financial situation satisfaction	0.7	0.9	2.7	0.8	-0.3	-0.5	-1.4	1.6	-0.7	-0.2	-1.6	-0.2	0.3
Tinnitus: Yes, now most or all of the time	3.2	3.8	10.8	-1.3	0.4	1.9	-2.8	3.3	1.8	1.3	-1.7	1.6	1.7
Commuting to job workplace: Public transport	1.0	1.2	2.9	-1.7	-1.2	-1.2	0.1	-0.7	-1.2	-1.1	-0.7	-1.3	-0.6
Eye problems/disorders: Glaucoma	0.4	0.4	1.3	0.2	1.2	-0.1	0.7	-0.7	-0.2	0.7	0.6	1.0	-0.1
Medication: Blood pressure	1.4	2.7	4.5	-2.0	-1.6	-2.1	1.1	-0.2	-2.1	-2.0	-0.9	-1.4	-1.7
Pain type(s) experienced in last month: Hip pain	0.5	0.7	1.4	-0.1	1.2	0.7	-1.2	0.8	0.7	0.3	-1.2	0.4	0.8
Supplements: Fish oil (including cod liver oil)	1.3	1.8	6.2	1.6	-0.4	0.7	-1.5	1.6	0.7	0.9	-2.5	0.7	1.3
High cholesterol (Self-reported)	0.9	1.7	10.3	-1.2	-0.1	-0.5	-1.3	0.9	-0.4	-1.2	-3.2	-0.8	0.3
Medication: Bendroflumethiazide	0.4	0.6	1.2	1.1	0.2	-0.7	0.5	1.0	-0.8	-0.9	-1.0	-0.9	-0.4
Medication: Paracetamol	0.2	0.3	0.7	-0.1	-0.5	-0.7	-0.2	0.6	-0.8	0.0	-0.3	0.8	-0.6
Medication: Lisinopril	2.8	3.6	8.1	-2.1	-1.4	-2.2	1.4	-1.1	-2.0	-2.9	-1.7	-2.2	-1.2
Medication: Atorvastatin	0.8	0.9	2.7	1.1	-0.1	-0.3	0.4	-1.6	0.0	-1.6	0.1	-1.5	-0.6
Illnesses of father: High blood pressure	1.9	2.3	4.2	0.8	-2.1	-1.3	1.7	-1.7	-1.0	-1.7	1.7	-1.7	-1.1
Alcohol drinker status: Never	0.3	0.3	0.8	0.7	-0.8	-0.0	-0.4	0.9	-0.1	0.2	-0.7	0.7	0.5
Ever smoked	0.3	0.6	1.7	-0.5	1.3	-0.5	-0.0	-0.7	-0.5	-1.0	0.8	-0.6	-1.0
Basal metabolic rate	1.7	9.3	22.4	-0.8	-1.2	-4.3	4.7	-2.1	-4.6	-3.4	-0.9	-1.9	-2.9
Leg fat percentage (left)	0.4	1.5	7.5	-2.7	-0.5	0.0	-2.0	-0.0	0.2	-1.0	-1.3	-0.8	0.3
Arm fat-free mass (left)	1.6	7.9	18.3	-0.9	-1.1	-4.0	4.3	-2.0	-4.2	-3.2	-1.2	-1.6	-2.7
Number of operations (self-reported)	1.1	1.7	5.0	0.7	2.2	0.0	2.0	-0.8	-0.3	1.3	1.1	1.9	0.0
Average weekly beer plus cider intake	0.3	0.4	1.5	-1.2	-0.3	-0.7	0.2	-0.0	-0.7	-0.8	-0.7	-0.3	-0.6
Irritability	0.1	0.2	0.7	0.4	0.8	0.1	-0.0	-0.2	-0.1	0.5	-0.3	0.7	0.3
Risk taking	0.4	0.6	2.7	0.4	0.7	-0.1	1.4	-0.0	-0.1	0.5	1.7	0.6	-0.4
Ever had prostate specific antigen (PSA) test	0.8	0.9	3.3	0.1	-0.6	-0.0	-1.7	1.5	0.0	-0.3	-1.8	-0.1	-0.0
Fractured/broken bones in last 5 years	0.1	0.1	0.3	0.5	-0.1	0.3	0.0	0.1	0.2	0.6	-0.0	0.4	-0.1
Age started oral contraceptive pill	1.0	1.2	4.9	0.3	-1.4	-0.3	-1.4	0.8	-0.1	-1.1	-2.2	-1.2	0.0
Diastolic blood pressure, automated reading	2.0	6.2	11.4	-2.9	-2.1	-3.4	1.4	-2.2	-3.3	-3.1	-0.0	-2.3	-2.3
Ever depressed for a whole week	2.6	3.2	10.2	-1.3	-1.2	-1.8	-0.1	-1.1	-1.5	-3.2	-0.8	-2.8	-2.0
Unable to work because of sickness or disability	0.5	0.6	1.9	-0.2	-0.2	-1.2	0.4	-0.8	-1.3	-0.0	0.4	0.2	-1.4
Commuting to job workplace: Cycle	0.9	1.1	2.4	0.9	1.5	0.9	1.6	0.2	0.8	0.9	-0.3	1.4	0.9
Myopia	0.1	0.2	0.9	0.6	0.1	-0.1	0.2	0.6	-0.1	0.1	-0.9	-0.2	0.3
Vascular/heart problems diagnosed by doctor	1.6	4.2	8.0	1.8	1.5	2.8	-0.4	0.6	2.7	2.8	2.4	2.2	1.7
Cholesterol lowering medication	0.4	0.5	1.9	-0.1	0.9	0.5	-0.7	1.1	0.6	-0.3	-1.4	-0.2	0.5
Medication: Omeprazole (e.g. Zanprol)	0.8	0.9	2.6	1.0	0.1	-1.5	0.9	-0.5	-1.6	-0.7	0.2	-0.5	-1.4
Pain experienced in last month	1.1	1.9	6.3	-0.8	1.1	2.3	-0.5	0.7	2.5	1.0	0.3	0.1	1.9
Supplements: Calcium	0.7	0.8	2.1	1.0	-1.0	-1.2	0.3	0.3	-1.4	-0.3	-0.2	-0.1	-1.4
Basal cell carcinoma (self-reported)	0.5	0.6	4.3	-0.4	-0.2	-0.7	-0.1	-2.1	-0.7	-0.2	-0.0	-0.1	-0.8
Heart attack/myocardial infarction (self-reported)	0.4	0.5	1.5	-0.6	-0.4	-0.6	-0.6	-0.6	-0.5	-1.1	-1.2	-0.9	-0.0
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	4.3	0.2	1.1	1.0	0.3	-0.5	1.1	0.5	2.1	0.3	-0.3
Heart disease (siblings)	1.9	2.4	3.3	-0.2	1.7	1.7	-1.5	1.0	1.6	1.8	-1.4	1.8	1.8
Alcohol drinker status: Previous	0.6	0.7	2.1	0.2	-0.9	-1.0	-0.2	-0.8	-0.9	-0.5	0.5	-0.8	-1.5
Pack years of smoking	0.7	1.0	2.7	-1.0	-0.4	-1.4	0.5	-0.6	-1.4	-1.6	-0.4	-1.2	-0.7
Impedance of whole body	0.3	1.5	4.5	0.4	0.2	1.2	-2.1	1.0	1.2	1.6	0.8	0.8	1.4
Leg fat mass (left)	0.5	1.8	5.7	-2.4	-0.8	-1.3	0.1	-0.8	-1.2	-1.9	-1.3	-1.3	-0.6
Arm predicted mass (left)	1.6	8.2	19.4	-1.0	-1.0	-4.0	4.4	-1.9	-4.3	-3.3	-1.4	-1.7	-2.7