Hub : Genes

KHNYN

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.3400 0.0460 0.0e+00 0.194 0.195 0.263 0.235 0.256 4.0e-23 3.1e-23 6.9e-32 3.2e-28 5.0e-31
2 GTEx Adipose Subcutaneous 0.2960 0.0650 8.5e-06 0.139 NA 0.117 NA 0.145 1.8e-11 NA 9.1e-10 NA 7.1e-12
3 GTEx Adipose Visceral Omentum 0.1880 0.0640 9.7e-03 -0.003 NA -0.005 NA 0.000 4.6e-01 NA 8.2e-01 NA 3.0e-01
4 GTEx Artery Aorta 0.1900 0.0670 6.1e-03 0.199 NA 0.198 NA 0.204 3.5e-11 NA 3.8e-11 NA 1.8e-11
5 GTEx Artery Tibial 0.3786 0.0643 7.9e-09 0.124 NA 0.145 NA 0.176 6.3e-10 NA 1.9e-11 NA 8.8e-14
6 GTEx Cells Transformed fibroblasts 0.3300 0.0620 7.7e-07 0.176 NA 0.190 NA 0.157 3.7e-13 NA 3.4e-14 NA 7.3e-12
7 GTEx Lung 0.1409 0.0584 9.3e-03 0.080 NA 0.044 NA 0.050 1.0e-06 NA 2.5e-04 NA 9.7e-05
8 GTEx Muscle Skeletal 0.0791 0.0334 7.2e-03 -0.003 NA -0.002 NA -0.003 7.6e-01 NA 5.7e-01 NA 8.4e-01
9 GTEx Nerve Tibial 0.3362 0.0695 2.5e-05 0.101 NA 0.131 NA 0.146 1.3e-07 NA 1.5e-09 NA 1.6e-10
10 GTEx Whole Blood 0.1680 0.0490 3.1e-04 0.146 NA 0.118 NA 0.135 2.4e-13 NA 5.2e-11 NA 2.1e-12
11 METSIM Adipose 0.0447 0.0187 3.2e-03 0.037 0.018 0.020 0.022 0.030 2.8e-06 7.5e-04 3.9e-04 2.1e-04 2.2e-05
12 NTR Blood 0.0695 0.0203 5.2e-06 0.060 0.019 0.058 0.061 0.058 1.4e-18 8.3e-07 5.9e-18 6.6e-19 4.6e-18
13 YFS Blood 0.3591 0.0362 0.0e+00 0.202 0.237 0.291 0.278 0.290 3.5e-64 2.8e-76 1.2e-96 1.2e-91 5.9e-96
14 TCGA Brain Lower Grade Glioma 0.0585 0.0336 5.8e-03 0.002 0.008 0.011 NA 0.002 1.6e-01 3.8e-02 1.7e-02 NA 1.9e-01
15 TCGA Thyroid Carcinoma 0.0760 0.0370 1.7e-03 -0.002 0.014 0.006 NA -0.001 7.3e-01 1.3e-02 7.9e-02 NA 4.5e-01

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Bipolar Disorder (2018) 0.1 0.1 0.6 -0.2 0.7 0.1 0.2 0.4 -0.2 0.2 0.4 0.6 -0.0 -0.0 -0.0 0.5 -0.2 0.8
Bipolar Disorder or Schizophrenia 0.1 0.3 1.1 1.0 -0.2 -0.3 -0.1 -0.6 -0.5 -0.6 0.7 -0.2 -0.6 -0.6 -0.3 -0.0 0.4 0.9
Depressed Affect (Nagel 2018) 0.3 0.6 2.9 0.5 0.0 -1.0 -0.2 -0.2 -0.5 -0.3 -1.7 -0.5 -0.7 -0.7 -0.7 0.5 0.9 1.1
Depression (Nagel 2018) 0.2 0.4 0.8 0.5 -0.3 -0.9 -0.4 -0.5 -0.4 -0.6 0.1 -0.6 -0.8 -0.8 -0.7 -0.0 0.7 0.9
Intelligence (Savage-Jansen 2018) 2.0 6.2 10.4 0.9 -2.3 -2.6 -3.1 -2.6 -2.5 -3.0 1.9 -2.6 -3.2 -3.2 -3.2 -2.1 1.7 -0.6
Neuroticism (Nagel 2018) 0.2 0.4 2.4 -0.1 0.8 -0.6 0.3 0.7 0.3 0.3 -1.6 0.2 -0.2 -0.2 -0.4 0.9 0.2 0.9
Schizophrenia (2018) 0.3 0.7 2.2 1.5 -0.8 -0.5 -0.5 -1.1 -0.5 -0.9 1.2 -0.8 -0.7 -0.7 -0.7 -0.6 0.5 0.6
Schizophrenia vs Biploar Disorder 0.1 0.2 1.1 -0.4 0.3 0.4 0.5 0.1 1.0 0.3 0.6 0.1 0.1 0.1 0.3 0.1 -0.1 -0.4
Worry (Nagel 2018) 0.3 0.7 2.3 -1.4 1.3 -0.6 0.3 0.9 1.5 0.3 -1.2 0.6 -0.3 -0.3 -0.5 0.2 -1.2 -0.3
Alzheimer’s Disease (in mother) 0.1 0.1 0.5 0.0 0.2 0.2 0.1 0.2 -0.5 0.3 0.6 0.1 0.4 0.4 0.2 0.3 0.7 0.4
Alzheimer’s Disease (in father) 0.2 0.3 1.6 0.5 -0.3 0.2 -0.3 -0.1 -0.9 -0.0 1.3 -0.1 0.2 0.2 -0.2 -0.0 1.0 0.1
Alzheimer’s Disease (including proxy) 0.3 0.5 2.2 0.4 -0.0 0.4 -0.1 0.2 -1.3 0.2 1.3 0.1 0.4 0.4 -0.1 0.3 1.5 0.4
Crohns Disease (2017) 0.3 0.6 2.7 -1.4 0.6 -0.0 0.7 0.7 1.6 0.6 -0.2 0.6 0.3 0.3 0.8 0.3 0.5 -0.9
Irritable Bowel Disease (IBD) 0.2 0.5 1.1 -0.3 -0.4 -0.9 -0.5 -0.6 0.6 -0.7 0.1 -0.6 -0.9 -0.9 -0.6 -0.9 1.1 -1.0
Ulcerative Colitis (UC) 0.8 1.5 2.4 0.9 -1.3 -1.2 -1.1 -1.6 -1.0 -1.4 0.3 -1.4 -1.4 -1.4 -1.2 -1.4 1.4 -0.5
Major Depression (MDD) 0.3 0.4 2.1 1.2 0.0 -0.7 0.0 -0.4 -0.4 -0.5 -1.4 -0.4 0.0 0.0 -0.8 -0.3 -0.5 0.2
Reaction Time 1.2 2.3 5.2 0.4 -1.4 -1.7 -1.6 -1.7 -0.3 -1.7 2.3 -1.4 -1.8 -1.8 -1.8 -1.5 -0.9 -0.4
Verbal and Numeric Reasoning (VNR) 1.3 3.0 5.6 0.1 -1.5 -1.7 -2.1 -1.6 -1.8 -2.1 1.2 -1.8 -2.4 -2.4 -2.2 -1.6 0.5 -1.5
Breast Cancer 1.2 2.9 5.3 0.7 -1.6 -2.3 -2.2 -1.6 -0.5 -2.0 0.1 -1.9 -1.9 -1.9 -2.2 -2.0 0.3 -1.6
Ovarian Cancer 0.9 1.2 2.4 1.0 -1.3 -0.8 -1.2 -1.4 -1.2 -1.2 -0.2 -1.2 -1.1 -1.1 -1.2 -0.5 1.5 0.5
Prostate Cancer 0.1 0.1 0.4 -0.1 -0.2 -0.3 -0.3 -0.0 -0.1 -0.4 0.1 -0.2 -0.5 -0.5 -0.6 -0.1 0.4 -0.3
Age at First Birth 0.4 0.6 3.6 -0.1 -0.3 -0.5 -0.4 -0.1 -1.9 -0.3 1.7 -0.2 -0.2 -0.3 -0.6 -0.1 0.7 -0.7
Bipolar Disorder (2011) 0.1 0.1 1.3 0.0 0.0 0.0 0.0 0.0 -1.1 0.0 -0.8 0.0 0.0 0.0 0.5 0.2 0.0 0.0
Body Mass Index (BMI) (2010) 0.3 0.4 0.7 -0.8 0.7 0.4 0.7 0.7 0.7 0.6 -0.6 0.8 0.4 0.4 0.6 0.5 0.5 -0.1
Coronary Artery Disease (CAD) 0.3 0.4 1.9 -0.3 -0.2 0.5 0.6 0.1 -0.1 0.1 0.8 -0.1 0.2 0.2 1.1 -0.4 -1.4 -0.9
Crohns Disease (2012) 0.5 0.7 5.3 -1.1 0.8 0.6 0.5 0.7 2.3 0.8 -0.4 0.8 0.6 0.5 0.5 -0.0 -0.4 -0.6
Mean Putamen Volume 1.1 1.2 2.2 -1.4 1.3 0.5 1.1 1.2 0.4 1.0 -1.4 1.2 0.9 0.9 0.8 1.5 -1.3 1.3
Fasting Glucose 0.3 0.4 0.9 -0.7 0.7 0.9 0.5 0.7 0.9 0.6 0.1 0.6 0.5 0.5 0.3 0.7 -0.8 0.5
HbA1C 1.0 1.2 3.0 -0.4 0.7 1.4 1.4 1.0 -0.4 1.1 1.0 1.0 1.3 1.3 1.7 1.0 -0.6 0.5
HDL Cholesterol 0.1 0.2 0.8 -0.5 0.5 -0.3 -0.6 0.2 0.6 0.0 0.7 0.5 -0.0 -0.0 -0.6 -0.6 0.0 -0.9
LDL Cholesterol 1.0 1.7 4.8 -0.7 -1.0 -1.2 -1.2 -1.5 -0.1 -1.4 0.9 -1.6 -1.4 -1.5 -1.4 -1.4 -0.3 -2.2
Lupus 3.5 5.2 10.2 -2.8 3.2 1.2 2.2 2.7 3.0 2.3 -1.8 2.8 1.7 1.7 1.6 2.1 -3.0 0.6
Neuroticism (2016) 0.2 0.3 0.5 -0.3 0.7 0.3 0.5 0.7 0.1 0.6 0.2 0.6 0.7 0.7 0.6 0.6 -0.1 0.1
Primary Biliary Cirrhosis 0.2 0.3 3.4 0.3 0.2 -0.5 -0.0 0.0 0.3 0.0 0.2 0.2 0.1 0.1 -0.4 0.9 -0.0 1.8
Rheumatoid Arthritis 0.3 0.4 4.2 0.5 0.2 -0.4 0.2 -0.0 0.6 0.3 -2.0 0.4 0.2 0.2 0.0 0.6 -0.1 1.0
Schizophrenia (2014) 0.1 0.2 1.8 0.9 0.0 0.2 0.3 -0.3 0.5 -0.1 1.3 0.0 -0.0 -0.0 0.3 0.0 0.4 0.0
Triglycerides 0.3 0.5 3.0 -0.5 -0.5 -0.2 0.0 0.1 0.4 -0.3 1.6 -0.4 -0.1 -0.1 0.5 -0.8 -0.8 -1.7
Type 2 Diabetes (T2D) (2012) 0.6 0.7 1.7 -0.5 -0.6 -1.3 -1.2 -0.7 0.2 -0.8 0.6 -0.5 -0.8 -0.8 -1.2 -1.0 -0.2 -0.7
Ulcerative Colitis 0.1 0.1 0.5 0.5 -0.2 -0.2 -0.1 -0.5 0.4 -0.2 -0.6 -0.3 -0.1 -0.1 -0.4 -0.2 0.1 0.7
Blood Eosinophil Count 0.3 2.1 3.9 0.5 -1.1 -1.8 -1.6 -1.5 1.7 -1.6 -1.7 -1.4 -1.7 -1.7 -1.6 -2.0 0.2 -0.6
Blood Platelet Count 0.1 0.7 1.7 0.8 -1.1 -0.6 -1.0 -1.0 -0.0 -0.8 -0.4 -1.3 -0.9 -0.9 -1.0 -1.0 0.7 -0.4
Blood Red Count 0.1 0.6 3.5 -1.3 -0.1 0.7 0.3 -0.1 1.9 -0.1 -0.4 -0.2 -0.1 -0.1 0.4 -0.3 -0.1 -1.5
Blood White Count 0.4 2.7 11.7 3.3 -2.0 -0.3 -0.5 -1.4 -2.1 -0.7 0.0 -1.7 -0.1 -0.1 -0.3 0.3 1.9 3.4
Heel T-Score 0.7 5.6 14.2 0.7 -2.2 -2.4 -2.6 -2.3 -0.1 -2.2 3.3 -2.5 -2.1 -2.1 -1.9 -3.3 0.9 -3.8
BMI 0.1 0.8 4.9 -0.5 0.2 0.3 0.8 0.3 -0.6 0.7 -0.5 0.6 0.8 0.8 0.9 1.3 1.0 2.2
Height 3.0 57.7 89.5 -6.0 8.9 8.1 8.8 8.9 3.8 8.4 -9.5 8.5 7.7 7.7 8.2 7.8 -3.6 4.3
Waist Hip Ratio (WHR) 0.4 1.8 6.5 -1.3 1.5 0.5 1.4 1.2 2.5 0.8 -2.3 1.0 0.5 0.5 1.0 0.8 -1.9 -0.4
Systolic Blood Pressure 0.1 0.5 2.8 0.5 0.1 0.3 0.8 -0.4 -0.4 0.3 -1.7 0.5 0.5 0.5 0.9 0.4 1.2 0.7
Smoking Status 1.1 2.7 5.8 -0.6 1.2 2.4 1.8 1.4 0.5 1.9 -2.4 1.2 2.2 2.2 1.8 1.6 -0.5 1.1
Allergy or Eczema 0.5 1.2 2.9 0.4 -1.1 -1.1 -1.1 -0.9 -1.1 -1.2 1.3 -1.0 -1.1 -1.1 -0.7 -1.4 0.2 -1.7
Cardiovascular Disease 0.7 2.3 4.1 2.0 -1.7 -1.8 -1.5 -1.8 -1.5 -1.6 -0.9 -1.4 -1.5 -1.5 -1.7 -0.9 1.5 0.8
Hypothyroidism (self reported) 0.2 0.4 2.2 -0.2 0.4 -1.5 -0.2 -0.1 0.6 -0.7 -0.3 0.2 -0.9 -0.9 -0.8 0.0 0.2 -0.1
Respiratory disease 0.3 0.6 2.5 -1.6 0.8 0.7 0.6 1.1 0.4 0.7 0.4 0.8 0.5 0.5 0.7 0.2 -1.0 -0.9
Type 2 Diabetes (T2D) (2018) 0.4 0.7 4.8 0.2 -0.6 -0.6 -0.6 -0.9 -0.0 -0.6 -2.2 -0.6 -0.5 -0.5 -0.8 -0.1 -0.3 1.0
Lung FEV1/FVC ratio 0.4 1.9 3.4 -0.5 1.6 1.7 1.7 1.7 0.1 1.6 1.1 1.8 1.5 1.5 1.7 1.5 0.8 0.0
Lung FVC 0.2 1.0 4.0 -0.6 0.3 -0.8 -0.7 -0.2 -0.0 -0.5 -1.7 -0.2 -1.0 -1.0 -0.7 -1.4 -2.0 -1.6
Neuroticism 0.2 0.5 2.1 -1.0 1.0 -0.4 0.6 0.7 1.2 0.2 -1.4 0.3 -0.2 -0.2 -0.1 0.9 -0.2 0.7
Chronotype (morning person) 0.4 1.0 2.1 1.1 0.2 1.0 0.8 0.6 -1.2 1.0 -0.5 0.9 1.5 1.5 1.2 1.0 0.7 1.1
Hair Pigment 0.1 1.5 3.2 0.6 -0.8 -1.4 -1.4 -1.0 -0.2 -1.2 -1.3 -1.1 -1.5 -1.5 -1.2 -1.8 0.3 -1.8
Tanning 0.0 0.5 1.7 -0.3 -0.4 -0.3 -0.6 -0.3 0.3 -0.7 -1.1 -0.3 -0.8 -0.8 -0.6 -0.9 -0.7 -1.3
Hand grip strength (left) 0.2 0.6 6.6 -0.2 0.4 -0.5 -0.1 0.1 0.2 -0.1 -2.6 0.0 -0.4 -0.4 -0.6 0.7 0.7 0.9
Number of treatments/medications taken 0.4 0.7 3.0 -1.2 0.8 -0.7 0.1 0.3 0.8 -0.2 -1.5 0.5 -0.6 -0.6 -0.2 -0.4 -1.1 -1.7
Average weekly spirits intake 0.2 0.3 0.8 -0.9 0.4 0.3 0.6 0.6 0.4 0.5 0.7 0.6 0.4 0.4 0.8 0.5 -0.4 0.2
Sensitivity / hurt feelings 0.3 0.5 3.5 -0.3 0.6 -0.7 0.0 0.3 0.6 0.0 -1.0 0.3 -0.2 -0.2 -0.6 1.0 0.3 1.9
Frequency of depressed mood in last 2 weeks 0.2 0.3 1.2 1.1 -0.4 -0.8 -0.5 -0.4 -0.3 -0.4 0.2 -0.6 -0.5 -0.5 -0.5 0.1 0.6 0.9
Hearing difficulty/problems: Yes 1.4 2.1 3.3 -1.7 1.8 1.3 1.5 1.7 1.3 1.7 -1.4 1.6 1.3 1.3 1.3 1.6 -0.7 1.4
Relative age of first facial hair 0.6 1.2 9.6 -1.0 -0.2 -1.1 -0.8 -0.3 0.8 -0.7 -0.3 -0.6 -0.9 -0.9 -0.7 -1.4 -0.0 -3.1
Other serious medical condition/disability diagnosed by doctor 0.7 1.0 3.7 -1.9 1.2 0.0 0.2 0.6 1.2 0.2 -0.9 0.8 -0.5 -0.5 -0.0 -0.4 -1.8 -1.5
Ever used hormone-replacement therapy (HRT) 0.8 1.1 2.6 -0.2 -0.8 -0.5 -1.0 -0.9 -0.2 -1.1 -0.6 -1.2 -1.2 -1.2 -1.1 -1.6 -1.2 -1.2
Ever had hysterectomy (womb removed) 0.3 0.3 2.3 -0.7 0.4 0.5 0.3 0.3 0.4 0.3 0.1 0.4 0.2 0.2 0.4 -0.6 -0.8 -1.5
Systolic blood pressure, automated reading 1.0 2.8 5.3 -1.2 2.0 1.6 2.3 1.5 0.7 2.0 -0.6 2.1 1.9 1.9 2.2 1.9 -0.4 0.9
Eye problems/disorders: Diabetes related eye disease 1.6 1.8 2.6 1.4 -1.5 -1.4 -1.5 -1.4 -0.4 -1.6 -0.9 -1.5 -1.6 -1.6 -1.5 -1.4 0.5 -0.3
Angina 1.6 2.1 3.3 1.2 -1.8 -1.6 -1.8 -1.6 -1.0 -1.8 1.2 -1.6 -1.7 -1.7 -1.6 -1.5 -0.2 -0.5
Medication for hormone replacement therapy 2.2 2.4 4.0 0.5 -1.6 -1.3 -1.8 -1.9 -0.6 -1.9 0.9 -1.9 -1.9 -1.9 -1.7 -2.0 -1.0 -1.3
Vitamin and mineral supplements 0.4 0.5 1.7 0.2 -0.0 0.8 0.8 -0.1 0.5 0.5 1.2 -0.3 0.8 0.8 1.0 0.4 1.3 0.5
Supplements: Zinc 0.2 0.3 1.5 0.4 -0.1 0.3 -0.1 -0.2 -1.2 0.2 1.1 -0.1 0.3 0.3 0.2 0.0 1.0 0.1
Medication: Co-codamol 0.7 0.8 3.4 -0.9 0.3 -1.3 -0.2 0.0 1.0 -0.5 0.0 0.2 -0.8 -0.8 -0.3 -0.6 -1.9 -1.5
Medication: Metformin 0.4 0.6 2.1 0.4 -0.8 -0.9 -0.7 -0.7 -1.0 -0.7 -1.5 -0.6 -0.8 -0.8 -0.8 -0.2 -0.2 0.6
Diabetes (father) 0.2 0.3 1.2 0.9 -0.4 0.1 0.5 -0.4 -0.2 0.1 -0.3 -0.3 0.5 0.5 0.9 -0.1 1.1 0.5
Diabetes (mother) 1.0 1.2 2.2 0.3 -0.9 -1.1 -1.2 -1.1 -1.0 -1.1 -0.3 -1.1 -1.3 -1.3 -1.2 -1.3 1.1 -1.5
Severe depression (siblings) 3.0 3.4 5.6 -1.5 1.9 1.6 2.3 1.9 1.4 1.9 0.8 2.1 2.2 2.2 2.0 2.4 -0.5 1.8
Pack years adult smoking proportion 0.7 1.1 2.5 -0.7 1.0 1.1 1.1 0.8 1.0 1.1 -1.6 1.4 1.2 1.2 1.2 0.9 -0.7 -0.5
Impedance of leg (right) 1.1 5.1 15.8 4.0 -3.3 -1.0 -2.2 -2.6 -2.4 -2.2 2.1 -3.1 -1.4 -1.4 -1.6 -2.0 1.5 0.5
Leg fat-free mass (left) 1.9 10.3 16.7 -2.4 3.7 2.9 3.5 3.5 1.3 3.6 -3.9 3.7 3.3 3.3 3.2 4.1 0.6 3.1
Trunk fat percentage 0.3 1.1 3.5 1.9 -1.5 -0.4 -0.4 -1.0 -1.8 -0.7 -0.4 -1.1 -0.3 -0.3 -0.2 -0.2 1.2 1.9
Hand grip strength (right) 0.3 0.7 4.3 1.1 -0.4 -0.8 -0.3 -0.6 -0.5 -0.4 -2.1 -0.6 -0.4 -0.4 -0.5 0.2 1.2 0.9
Townsend deprivation index at recruitment 0.5 0.7 2.4 -1.0 -0.4 -0.4 -0.6 -0.4 0.9 -0.8 -0.1 -0.8 -1.0 -1.0 -0.6 -1.1 -0.9 -1.6
Current tobacco smoking 0.9 1.4 4.5 -0.3 0.8 2.1 1.1 0.9 -0.2 1.3 -1.7 0.9 1.6 1.6 1.2 1.2 -0.1 0.9
Average weekly fortified wine intake 0.2 0.3 1.8 -0.7 0.3 0.2 0.1 0.4 0.2 0.1 1.3 0.3 0.1 0.1 0.1 -0.3 -0.1 -1.2
Maternal smoking around birth 0.5 0.8 5.1 -0.3 0.6 1.2 0.4 0.3 -0.1 0.5 -2.3 0.1 0.5 0.5 0.1 0.7 -0.1 1.6
Fed-up feelings 0.4 0.7 3.0 0.9 -0.2 -1.0 -0.4 -0.4 -0.3 -0.6 -1.7 -0.4 -0.8 -0.8 -0.7 0.6 0.6 1.6
Frequency of unenthusiasm / disinterest in last 2 weeks 0.9 1.2 2.9 0.7 -0.6 -1.7 -1.2 -1.0 -0.1 -1.3 0.4 -1.0 -1.6 -1.6 -1.3 -0.7 0.9 -0.1
Relative age voice broke 1.9 2.9 4.7 0.6 -1.8 -2.1 -2.1 -1.7 -0.9 -2.1 -0.1 -2.0 -2.1 -2.1 -2.2 -2.0 0.7 -1.1
Taking other prescription medications 3.1 4.8 20.5 -1.8 -0.1 -2.8 -1.3 -0.8 1.6 -1.9 -1.3 -0.8 -2.6 -2.6 -1.6 -2.6 -2.8 -4.5
Age when periods started (menarche) 1.7 4.1 9.4 -2.3 2.1 1.7 2.0 2.1 3.1 2.4 0.1 2.3 2.2 2.2 2.3 1.3 -0.7 -1.9
Bilateral oophorectomy (both ovaries removed) 1.7 1.9 3.9 -0.2 1.2 1.8 1.8 1.3 0.0 1.5 -0.0 1.3 1.8 1.8 1.4 1.8 0.1 2.0
Heel bone mineral density (BMD) T-score, automated (left) 0.3 0.6 2.0 0.8 -0.5 -0.8 -0.6 -0.3 0.6 -0.5 1.3 -0.2 -0.4 -0.4 -0.3 -0.8 1.1 -1.4
Tinnitus: Yes, but not now, but have in the past 1.2 1.3 2.4 1.1 -1.1 -1.0 -1.2 -1.2 -1.5 -1.1 1.1 -1.3 -1.2 -1.2 -1.1 -0.5 1.6 0.7
Qualifications: CSEs or equivalent 1.4 1.9 6.5 -1.0 1.3 0.9 1.2 1.5 2.5 1.4 -1.5 1.3 1.3 1.3 1.1 0.8 -1.7 -0.4
Serious illness, injury or assault to yourself 2.5 3.0 10.0 1.4 -1.5 -1.4 -1.8 -1.4 -0.8 -1.7 0.9 -1.9 -1.8 -1.8 -1.6 -2.6 -0.6 -3.2
High blood pressure 0.2 0.5 2.2 1.5 -0.9 -0.8 -0.3 -0.9 -1.2 -0.7 0.2 -0.6 -0.5 -0.5 -0.4 -0.1 0.6 0.5
Hayfever, allergic rhinitis or eczema 0.7 1.5 2.3 0.5 -1.4 -1.3 -1.4 -1.2 -0.9 -1.4 1.0 -1.2 -1.3 -1.3 -1.0 -1.5 0.1 -1.5
Multivitamins +/- minerals 0.2 0.3 1.5 -0.2 0.3 -0.5 -0.5 0.3 0.4 -0.2 -1.2 0.5 -0.3 -0.3 -0.7 -0.3 -0.1 -0.8
Stomach or abdominal pain in last month 0.8 1.0 5.7 -0.6 1.0 0.9 0.9 0.8 0.9 1.0 -2.4 0.7 0.6 0.6 0.8 0.9 -0.7 0.5
Supplements: Glucosamine 1.9 2.5 7.3 -1.3 -0.5 -1.9 -1.4 -1.1 -1.0 -1.7 -0.4 -0.9 -2.0 -2.0 -1.8 -1.9 -1.6 -2.7
Diverticular disease/diverticulitis (self-reported) 1.2 1.5 3.0 0.8 0.8 1.7 1.3 1.0 0.5 1.3 0.5 0.9 1.5 1.5 1.2 1.5 1.4 1.4
Medication: Atenolol 0.5 0.7 2.4 1.1 0.1 0.8 0.8 0.2 -1.0 0.6 1.6 0.5 0.9 0.9 1.2 0.3 0.3 0.3
Medication: Levothyroxine sodium 0.3 0.6 1.8 -0.7 0.7 -0.8 0.0 0.4 0.8 -0.3 -1.3 0.5 -0.6 -0.6 -0.7 1.1 -0.1 1.4
Sitting height 3.4 24.2 35.3 -3.4 5.9 5.2 5.5 5.7 3.1 5.7 -4.7 5.7 5.4 5.4 5.0 5.7 0.2 3.9
Chronic bronchitis/emphysema (father) 0.2 0.2 1.0 -0.4 0.3 0.3 0.3 0.1 0.1 0.2 -0.6 0.0 0.1 0.1 0.1 0.4 -0.9 1.0
High blood pressure (mother) 0.4 0.6 1.1 0.1 -0.8 -0.9 -0.8 -1.0 0.3 -0.8 -0.4 -1.0 -0.8 -0.8 -0.5 -1.0 -0.4 -1.1
Body mass index (BMI) 0.1 0.3 1.8 0.3 -0.4 -0.3 0.1 -0.3 -0.7 0.1 -0.4 -0.1 0.1 0.1 0.1 0.5 1.2 1.4
Impedance of leg (left) 0.7 3.2 10.4 3.2 -2.7 -0.9 -1.7 -2.1 -1.6 -1.9 1.4 -2.5 -1.2 -1.2 -1.2 -1.8 0.8 0.0
Leg predicted mass (left) 1.9 10.1 16.5 -2.3 3.6 2.8 3.5 3.5 1.2 3.6 -4.0 3.7 3.2 3.2 3.1 4.1 0.6 3.2
Trunk fat mass 0.3 1.2 5.8 0.7 0.1 0.8 0.9 0.4 -0.9 0.7 -1.5 0.4 1.0 1.0 1.1 1.2 1.1 2.4
Waist circumference 0.3 1.0 4.0 -0.6 0.8 0.7 1.3 0.7 0.1 0.9 -2.0 0.8 0.8 0.8 1.2 1.3 0.2 1.4
Number of incorrect matches in round 0.1 0.2 1.1 -0.1 0.0 0.0 -0.1 0.1 0.7 -0.1 -0.9 -0.4 -0.2 -0.2 -0.2 -0.7 -0.7 -1.0
Past tobacco smoking 1.5 2.8 4.7 0.8 -1.3 -2.2 -2.0 -1.5 -0.6 -1.9 2.0 -1.2 -2.1 -2.1 -2.1 -1.9 -0.1 -1.4
Alcohol usually taken with meals 0.6 1.0 1.8 0.7 -1.0 -0.8 -1.1 -0.9 -1.3 -1.2 0.4 -1.2 -1.1 -1.1 -1.2 -0.7 -0.2 1.0
Nervous feelings 0.3 0.5 1.6 -0.2 -0.1 -1.2 -0.8 -0.6 0.2 -0.7 0.3 -0.5 -1.1 -1.1 -1.3 -0.6 0.1 -0.6
Frequency of tenseness / restlessness in last 2 weeks 0.1 0.2 0.7 -0.1 0.3 -0.8 -0.3 -0.1 0.1 -0.4 -0.4 -0.0 -0.7 -0.7 -0.6 -0.0 -0.4 -0.5
Hearing difficulty/problems with background noise 0.5 0.8 2.5 -1.5 1.1 0.1 0.5 0.8 1.6 0.8 -1.1 0.8 0.2 0.2 0.5 0.5 -1.1 0.2
Hair/balding pattern: Pattern 2 2.3 3.0 4.7 1.9 -2.2 -1.8 -1.8 -2.1 -1.4 -1.9 1.0 -2.1 -1.8 -1.8 -1.6 -2.1 0.6 -0.8
Had menopause 1.3 1.6 3.9 -2.0 1.4 1.2 1.4 1.3 0.8 1.2 1.3 1.3 1.1 1.1 1.5 0.6 -1.2 -0.9
Had other major operations 4.9 5.9 12.1 -3.5 3.3 2.2 2.5 3.0 2.5 2.6 -1.6 3.0 2.2 2.2 2.2 1.9 -1.6 0.3
Forced vital capacity (FVC) 1.3 4.9 12.2 -1.4 2.7 2.1 2.3 2.3 1.2 2.3 -3.5 2.3 2.1 2.1 1.9 2.5 0.0 2.5
Heel bone mineral density (BMD) T-score, automated (right) 0.3 0.8 3.1 1.1 -0.4 -0.4 -0.6 -0.2 0.8 -0.2 1.5 -0.2 -0.2 -0.2 -0.4 -1.0 1.6 -1.8
Ever unenthusiastic/disinterested for a whole week 0.4 0.5 2.2 -0.5 1.0 0.0 0.5 0.7 0.5 0.6 -1.5 1.1 0.4 0.4 0.4 0.5 -0.9 0.1
Qualifications: None of the above 0.6 1.3 8.3 -1.0 0.8 0.8 0.7 0.7 1.1 0.9 1.1 0.9 0.7 0.7 1.0 -0.7 -1.1 -2.9
Financial difficulties in last 2 years 0.9 1.2 3.6 1.9 -0.9 -1.1 -1.3 -1.2 -0.6 -1.0 0.2 -1.0 -1.1 -1.1 -1.0 -0.9 1.8 -0.1
Mouth/teeth dental problems 0.5 0.7 2.1 -0.7 0.4 1.4 0.8 0.6 -0.4 0.8 1.4 0.9 0.9 0.9 0.8 0.9 -0.0 0.7
Heart attack 0.3 0.3 0.7 0.7 -0.8 -0.6 -0.6 -0.5 -0.8 -0.5 0.8 -0.5 -0.4 -0.4 -0.4 -0.3 -0.6 0.3
Allergy 0.2 0.4 1.9 0.4 0.3 0.6 0.6 0.4 0.3 0.6 -0.4 0.5 0.6 0.6 0.2 1.1 0.7 1.4
Pain all over the body in last month 0.2 0.2 2.6 0.1 -0.3 0.3 0.0 0.0 0.3 0.1 1.6 0.1 0.2 0.2 0.3 0.1 -0.6 -0.3
Diabetes (self-reported) 0.6 1.0 2.4 1.5 -1.4 -0.6 -1.0 -1.2 -0.9 -0.8 -1.1 -1.2 -0.7 -0.7 -0.9 -0.9 0.7 -0.1
Hayfever/allergic rhinitis (self-reported) 0.6 0.8 2.1 0.8 -0.9 -0.7 -1.0 -0.7 -1.5 -0.9 1.1 -1.0 -0.8 -0.8 -0.8 -0.7 0.7 -0.2
Medication: Ramipril 0.6 0.8 3.6 1.9 -1.2 -0.9 -0.4 -1.0 -1.1 -0.8 0.5 -0.8 -0.6 -0.6 -0.2 -0.1 0.5 0.8
Medication: Simvastatin 3.7 5.4 8.2 2.3 -2.9 -2.5 -2.8 -2.9 -2.4 -2.5 -0.8 -2.8 -2.3 -2.3 -2.8 -1.9 1.4 0.1
Fluid intelligence score 1.7 3.5 6.2 0.9 -1.9 -2.0 -2.0 -1.9 -1.9 -2.2 2.5 -1.8 -2.1 -2.1 -1.9 -1.6 0.8 -1.7
Illnesses of siblings 2.0 2.9 4.4 -1.3 1.6 2.1 1.9 2.0 1.9 2.1 -0.0 1.9 1.9 1.9 2.1 1.8 0.4 0.3
Neuroticism score 0.4 0.8 2.3 0.0 -0.2 -1.5 -0.6 -0.5 0.3 -0.9 -1.3 -0.8 -1.3 -1.3 -1.1 -0.3 -0.3 0.5
Weight 1.2 6.0 9.8 -1.2 2.3 2.3 2.7 2.4 0.5 2.7 -3.1 2.5 2.7 2.7 2.6 3.1 0.9 3.0
Impedance of arm (right) 1.2 5.6 10.8 3.2 -3.3 -1.2 -2.6 -2.6 -2.1 -2.6 2.3 -3.3 -1.9 -1.9 -2.0 -3.0 0.7 -0.4
Arm fat percentage (right) 0.7 2.7 5.6 2.1 -2.4 -1.4 -1.5 -2.0 -2.3 -1.6 1.0 -2.0 -1.2 -1.2 -1.2 -1.2 1.6 1.1
Trunk fat-free mass 3.7 21.2 31.7 -3.6 5.5 4.2 5.2 5.2 2.6 5.3 -5.0 5.5 4.9 4.9 4.7 5.6 -0.1 3.4
Hip circumference 0.2 1.0 5.0 0.9 -0.2 0.7 0.7 0.1 -1.1 0.5 -0.7 0.1 0.9 0.9 1.0 1.0 1.8 2.2
Time employed in main current job 1.2 1.4 8.1 -1.1 1.0 -0.2 0.2 0.5 2.0 0.2 0.2 1.0 -0.2 -0.2 0.2 -0.7 -2.8 -2.0
Alcohol intake versus 10 years previously 0.2 0.3 2.0 -1.0 0.1 0.4 0.4 0.1 -0.1 0.3 -1.4 0.1 0.3 0.3 0.5 0.3 -0.7 0.5
Father’s age at death 0.1 0.1 0.8 -0.5 0.0 0.1 0.3 0.2 -0.6 -0.0 0.3 0.3 -0.1 -0.1 0.2 -0.1 -0.3 -0.9
Worrier / anxious feelings 0.4 0.8 1.9 -1.0 1.1 0.3 0.8 1.1 0.6 0.7 -0.4 0.9 0.5 0.5 0.3 1.3 -1.4 1.2
Frequency of tiredness / lethargy in last 2 weeks 0.3 0.4 1.6 -0.7 0.9 0.4 0.5 0.9 0.8 0.7 0.1 0.6 0.4 0.4 0.4 0.5 -1.3 -0.3
Falls in the last year 0.2 0.2 1.5 0.3 0.2 -0.1 -0.4 0.2 -0.3 -0.1 -1.2 0.1 -0.2 -0.2 -0.3 -0.4 -0.5 -0.8
Hair/balding pattern: Pattern 3 0.4 0.7 2.4 -0.2 -0.1 -0.8 -0.8 -0.4 -0.2 -0.6 1.5 -0.0 -0.9 -0.9 -0.9 -0.8 -0.4 -1.6
Number of live births 0.2 0.2 1.0 -0.6 0.6 -0.1 0.1 0.2 0.7 0.3 0.7 0.7 0.1 0.1 0.2 -0.0 -0.0 -1.0
Forced expiratory volume in 1-second (FEV1) 1.0 3.5 7.1 -0.9 2.4 1.9 2.1 2.1 1.0 2.1 -2.7 2.1 1.8 1.8 1.9 2.1 0.2 1.4
Pulse rate 3.7 6.3 11.3 2.7 -2.5 -2.6 -3.3 -2.4 -0.5 -2.8 1.2 -2.7 -2.8 -2.8 -3.4 -2.5 2.2 -1.5
Happiness 0.8 1.0 2.9 0.7 -0.4 -1.7 -1.0 -0.5 -0.9 -1.1 0.4 -0.9 -1.4 -1.4 -1.7 -0.2 -0.3 0.7
Noisy workplace 0.2 0.2 0.6 0.5 0.5 0.0 0.4 0.3 0.8 0.6 -0.2 0.5 0.5 0.5 0.5 0.2 0.4 -0.1
Qualifications: A levels/AS levels or equivalent 1.9 4.2 9.6 2.4 -2.3 -1.8 -2.2 -2.2 -3.1 -2.2 1.4 -2.1 -2.0 -2.0 -2.2 -1.1 2.0 0.5
Serious illness, injury or assault of a close relative in last 2 years 0.2 0.3 2.0 0.4 -0.5 0.3 -0.1 -0.6 -0.7 -0.2 1.4 -0.4 -0.2 -0.2 0.1 -0.3 0.7 -0.2
Mouth/teeth dental problems: Dentures 1.2 2.0 4.4 -0.5 -0.8 -1.6 -1.6 -1.1 -0.2 -1.4 -1.9 -1.1 -1.6 -1.6 -1.5 -2.1 -1.1 -1.7
Asthma 0.7 1.4 3.5 -1.9 1.4 1.2 1.3 1.4 0.7 1.3 0.4 1.2 1.1 1.1 1.3 0.9 -1.1 -0.2
Medication: Ibuprofen (e.g. Nurofen) 1.3 1.7 3.8 -1.6 1.3 1.9 1.3 1.0 1.9 1.2 -1.7 1.0 0.9 0.9 1.1 1.4 -0.7 0.9
Medication: Cholesterol lowering 4.2 6.5 10.7 2.0 -3.0 -3.3 -3.1 -3.0 -1.9 -3.0 -0.4 -2.9 -2.8 -2.8 -3.2 -2.6 0.0 -1.1
Depression (self-reported) 0.4 0.5 1.6 -0.4 1.3 0.2 0.9 0.9 0.7 0.8 0.1 1.1 0.5 0.5 0.6 0.4 -0.9 -0.3
Medication: Lansoprazole 0.6 0.6 3.0 -1.4 0.7 0.0 0.4 0.9 0.9 0.1 0.9 0.7 0.0 0.0 0.3 0.0 -1.7 -1.0
Prospective memory result 0.6 0.7 1.8 -0.9 0.9 1.3 0.5 1.1 0.9 1.2 0.2 0.9 1.0 1.0 0.5 0.1 0.3 0.4
Lung cancer (father) 0.9 1.1 3.0 -0.8 0.9 1.1 0.7 0.9 -0.5 1.0 -1.6 0.9 1.0 1.0 0.6 1.4 -0.0 1.7
Illnesses of mother 0.7 0.8 3.2 0.1 0.6 0.9 0.8 0.9 0.1 0.9 0.3 1.1 1.1 1.1 0.7 1.3 0.2 1.8
Forced expiratory volume in 1-second (FEV1), Best measure 0.6 1.9 7.9 -0.4 1.6 1.2 1.2 1.4 0.4 1.2 -2.8 1.4 1.0 1.0 0.8 1.6 0.3 1.9
Pulse wave Arterial Stiffness index 2.5 3.0 6.8 -2.6 2.4 1.3 1.7 2.3 1.9 1.6 -1.6 2.1 1.2 1.2 1.2 1.1 -1.5 -1.0
Impedance of arm (left) 0.9 4.1 8.7 2.9 -2.8 -0.9 -2.0 -2.2 -1.9 -2.3 2.2 -2.8 -1.6 -1.6 -1.5 -2.6 0.6 -0.6
Arm fat mass (right) 0.1 0.5 3.3 0.7 -0.4 -0.0 0.2 -0.2 -1.1 0.2 -0.7 -0.1 0.3 0.3 0.3 0.7 1.2 1.8
Trunk predicted mass 3.5 19.9 29.5 -3.5 5.4 4.0 5.0 5.0 2.5 5.2 -5.0 5.3 4.7 4.7 4.5 5.4 -0.1 3.2
Standing height 2.9 29.1 38.5 -3.3 6.1 5.9 6.1 6.2 2.7 6.2 -5.9 6.0 6.0 6.0 5.8 6.2 -0.4 4.2
Length of working week for main job 1.3 1.4 5.4 1.3 -1.2 -0.4 -1.4 -1.0 -0.0 -1.1 0.7 -1.0 -1.1 -1.1 -1.4 -1.2 2.3 -1.0
Exposure to tobacco smoke at home 0.4 0.4 1.6 -0.4 -0.2 -0.5 -0.4 -0.4 -0.2 -0.5 -1.3 -0.3 -0.7 -0.7 -0.5 -0.8 -0.8 -1.1
Breastfed as a baby 1.7 2.1 16.3 -1.1 0.1 -0.0 -0.4 0.1 1.5 -0.2 2.5 0.1 -0.5 -0.5 0.1 -1.5 -1.7 -4.0
Tense / ‘highly strung’ 1.8 3.0 5.6 -0.2 -1.1 -2.4 -1.9 -1.3 1.0 -2.0 -1.1 -1.5 -2.3 -2.3 -2.3 -2.1 -0.6 -2.1
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.4 1.9 -0.2 0.7 -0.4 0.5 0.5 0.9 0.2 -1.4 0.4 -0.1 -0.1 -0.1 0.5 -1.4 0.3
Hair/balding pattern: Pattern 4 0.8 1.8 2.7 -1.4 1.6 1.6 1.6 1.6 1.6 1.4 -0.7 1.5 1.4 1.4 1.3 1.5 0.2 0.1
Birth weight of first child 0.8 1.5 2.4 -1.0 1.3 1.4 1.2 1.1 -0.1 1.4 -1.5 1.1 1.5 1.5 1.0 1.5 -0.1 1.5
Peak expiratory flow (PEF) 0.4 0.9 4.2 2.0 -0.8 -0.3 0.1 -0.7 -1.6 -0.2 -0.0 -0.4 -0.0 -0.0 0.5 0.2 2.0 1.1
Pulse wave reflection index 4.2 5.2 7.9 -1.6 2.5 2.6 2.8 2.6 0.1 2.6 -1.6 2.3 2.6 2.6 2.4 2.8 -0.6 2.2
Ever highly irritable/argumentative for 2 days 0.5 0.6 2.7 -0.5 0.4 -1.1 -0.4 -0.0 1.6 -0.4 -0.9 0.3 -0.8 -0.8 -0.8 -0.2 -1.1 -0.3
Loud music exposure frequency 0.9 1.0 1.6 0.6 -1.0 -1.0 -1.3 -1.0 0.1 -1.2 0.5 -1.2 -1.3 -1.3 -1.0 -1.3 -0.3 -1.2
Qualifications: O levels/GCSEs or equivalent 2.2 3.5 6.2 1.6 -2.3 -1.7 -2.2 -2.3 -2.3 -2.2 -0.4 -2.5 -1.9 -1.9 -2.3 -1.2 0.2 1.4
Mouth/teeth dental problems: Bleeding gums 0.3 0.4 2.5 0.7 -0.0 -0.5 0.2 -0.0 0.4 0.0 -1.4 -0.2 0.2 0.2 0.1 0.8 0.1 1.6
Blood clot in the leg (DVT) 0.1 0.2 0.9 -0.3 0.3 0.3 0.1 -0.1 -0.9 0.0 -0.7 -0.3 -0.2 -0.2 -0.0 -0.6 0.3 0.0
Medication: Paracetamol 0.3 0.4 2.4 -0.4 0.5 0.1 0.2 0.4 1.1 0.2 -0.4 0.4 -0.1 -0.1 0.5 -0.3 -1.3 -1.5
Headache pain in last month 0.9 1.6 4.2 -1.6 2.1 0.7 1.1 1.7 1.0 0.9 -1.8 1.7 0.4 0.4 0.8 1.1 -1.4 0.2
Medication for cholesterol, blood pressure or diabetes 1.0 1.7 3.9 -1.7 1.5 1.8 1.3 1.3 2.0 1.3 1.0 1.3 1.0 1.0 1.4 0.5 -0.3 -0.3
Glaucoma (self-reported) 0.8 1.0 3.0 -0.4 -0.3 -1.1 -0.9 -0.5 1.7 -0.9 -0.3 -0.7 -1.2 -1.2 -1.1 -0.9 -1.0 -1.4
Gout (self-reported) 0.5 0.7 3.9 0.3 -0.5 -1.0 -0.2 -0.5 -0.4 -0.6 1.8 -0.1 -0.5 -0.5 0.1 -1.0 0.5 -2.0
Hypothyroidism/myxoedema (self-reported) 0.4 0.8 2.2 -1.3 1.3 -0.9 0.2 0.9 1.5 0.0 -1.1 0.9 -0.5 -0.5 -0.6 1.0 -0.8 0.8
Medication: Amlodipine 0.4 0.6 3.3 0.5 0.1 0.8 0.6 0.0 0.4 0.7 -0.5 0.0 0.9 0.9 0.6 1.0 -0.2 1.8
Medication: Ventolin 100micrograms inhaler 3.2 4.1 6.0 -2.0 2.3 1.8 2.3 2.4 1.1 2.4 -1.8 2.4 2.3 2.3 2.2 2.2 -1.1 0.7
Birth weight 2.3 5.0 13.9 -3.7 3.0 1.0 2.0 2.3 3.2 2.2 -2.5 2.6 1.6 1.6 1.5 1.5 -1.9 -0.5
Chronic bronchitis/emphysema (mother) 1.9 2.2 4.4 0.7 0.8 2.1 1.6 1.1 -0.4 1.5 1.6 1.2 1.8 1.8 1.7 1.7 0.5 2.0
High blood pressure (siblings) 0.2 0.2 1.3 -0.0 0.4 -0.0 -0.2 0.0 -1.0 -0.1 -1.1 -0.0 -0.3 -0.3 -0.6 0.2 -0.1 0.4
Forced vital capacity (FVC), Best measure 0.8 2.8 11.9 -0.9 1.9 1.4 1.3 1.5 0.7 1.5 -3.5 1.6 1.2 1.2 0.9 1.9 0.2 2.6
Body fat percentage 0.4 1.7 4.2 2.0 -2.0 -0.9 -0.9 -1.5 -2.1 -1.1 0.5 -1.6 -0.7 -0.7 -0.6 -0.7 1.4 1.3
Leg fat percentage (right) 0.7 2.6 6.2 2.2 -2.5 -1.1 -1.4 -1.9 -2.3 -1.4 1.0 -2.1 -1.0 -1.0 -0.9 -1.0 1.7 1.0
Arm fat-free mass (right) 2.9 14.8 24.6 -2.9 4.6 3.2 4.3 4.2 2.3 4.4 -4.8 4.5 3.8 3.8 3.8 5.0 0.2 3.2
Exposure to tobacco smoke outside home 0.6 0.8 1.4 -1.2 1.0 -0.0 1.0 1.1 0.1 1.0 -0.9 1.0 1.0 1.0 0.9 1.0 -0.7 0.4
Comparative body size at age 10 0.3 0.7 5.2 -0.4 0.4 0.4 0.2 0.5 -0.5 0.8 -1.0 0.2 1.0 1.0 0.2 1.1 0.4 2.3
Number of full brothers 0.5 0.6 2.7 0.1 -0.5 -0.4 -0.3 -0.7 -1.4 -0.7 1.6 -0.2 -0.7 -0.7 -0.2 -0.7 -0.5 -0.9
Worry too long after embarrassment 0.2 0.3 1.2 -1.1 0.7 0.3 0.6 1.0 0.3 0.5 -0.4 0.5 0.3 0.3 0.5 0.5 -0.2 -0.4
Seen a psychiatrist for nerves, anxiety, tension or depression 0.6 0.7 2.3 0.6 -0.2 -1.3 -0.9 -0.6 0.9 -1.0 -0.5 -0.4 -1.1 -1.1 -1.5 -0.6 0.7 -0.1
Wheeze or whistling in the chest in last year 1.1 1.9 6.1 -1.4 1.7 0.9 1.2 1.4 2.5 1.3 -1.0 1.4 1.1 1.1 1.2 0.1 -2.0 -1.0
Number of children fathered 0.2 0.2 1.5 -0.1 0.1 0.2 -0.1 0.3 -0.1 0.3 -0.2 0.3 0.4 0.4 -0.1 0.6 0.0 1.2
Reason for reducing amount of alcohol drunk: Health precaution 0.5 0.6 1.1 0.4 -0.7 -0.6 -0.9 -0.8 0.2 -1.0 -0.5 -0.8 -0.9 -0.9 -0.9 -1.1 0.2 -1.0
Age at first live birth 2.5 4.4 8.9 2.7 -2.1 -3.0 -1.9 -2.0 -2.3 -2.3 2.3 -2.3 -2.2 -2.2 -1.9 -1.3 1.4 -0.1
Pulse wave peak to peak time 1.9 2.2 6.5 2.5 -2.1 -0.9 -1.4 -1.9 -1.8 -1.2 1.1 -1.8 -0.8 -0.8 -0.9 -0.7 1.5 1.3
Health satisfaction 5.1 6.6 12.9 -3.5 3.6 2.4 2.6 3.2 3.2 2.8 -0.9 3.1 2.3 2.3 2.2 2.2 -1.7 0.3
Shortness of breath walking on level ground 1.6 1.9 5.4 -2.2 1.9 0.4 1.0 1.3 2.2 1.0 -0.1 1.8 0.4 0.4 0.8 0.5 -2.3 -1.1
Qualifications: College or University degree 0.2 0.8 4.1 0.6 -0.4 -0.2 0.1 -0.3 -1.8 -0.4 2.0 -0.2 -0.2 -0.2 0.0 0.4 1.6 0.7
Eye problems/disorders: None of the above 0.6 0.7 1.3 -0.4 0.8 1.0 0.7 0.9 0.4 1.0 0.7 1.1 1.1 1.1 0.7 0.9 -0.6 0.5
Mouth/teeth dental problems: Loose teeth 4.7 5.6 9.4 2.0 -3.0 -2.9 -2.7 -2.9 -1.6 -2.7 0.7 -3.1 -2.6 -2.6 -2.5 -2.3 0.2 -0.9
Emphysema/chronic bronchitis 0.1 0.1 0.6 0.4 -0.2 0.2 -0.4 -0.1 0.3 0.1 -0.8 -0.3 0.1 0.1 -0.3 -0.5 0.3 -0.0
Medication for pain relief, constipation, heartburn 0.2 0.3 1.5 -0.3 -0.3 -0.7 -0.3 -0.2 -0.9 -0.2 0.4 -0.2 -0.1 -0.1 -0.6 0.2 0.2 1.2
Neck or shoulder pain in last month 0.6 0.9 2.4 1.2 -0.5 -0.7 -0.7 -0.5 -0.7 -0.7 -1.6 -0.8 -0.9 -0.9 -0.6 -0.7 1.5 -1.0
Medication: Blood pressure 0.5 0.8 5.0 1.8 -0.9 -0.7 -0.1 -0.5 -2.2 -0.4 -0.1 -0.5 0.0 0.0 -0.0 0.5 0.6 1.3
Angina (self-reported) 2.5 3.3 5.2 1.7 -2.3 -1.9 -2.2 -2.0 -1.6 -2.2 1.2 -2.0 -2.1 -2.1 -2.0 -1.9 0.2 -0.4
Migraine (self-reported) 0.2 0.2 1.8 -0.4 0.2 0.1 -0.2 -0.0 0.4 -0.2 -1.4 -0.0 -0.4 -0.4 -0.3 0.2 -0.4 0.3
Medication: Ibuprofen 1.5 1.8 5.6 -1.9 1.4 1.8 1.2 1.0 1.7 1.0 -2.4 0.9 0.8 0.8 0.8 1.4 -0.5 1.2
Medication: Allopurinol 0.2 0.3 1.3 0.3 -0.3 -0.6 0.1 -0.2 -1.1 -0.2 0.9 -0.0 -0.1 -0.1 0.4 -0.7 0.0 -1.1
Medication: Omeprazole 0.3 0.3 1.5 -0.8 0.1 -0.2 -0.1 -0.1 0.7 -0.3 -0.1 -0.2 -0.6 -0.6 -0.4 -0.6 -1.2 -0.9
Medication: Seretide 50 evohaler 2.6 3.0 4.8 -2.2 2.1 1.3 1.9 2.0 1.4 1.9 -0.5 2.0 1.7 1.7 1.7 1.7 -1.9 1.2
Mean time to correctly identify matches 1.2 2.2 7.8 0.5 -1.3 -1.6 -1.5 -1.2 -0.2 -1.5 2.8 -1.3 -1.5 -1.5 -1.6 -1.8 -1.1 -1.4
Heart disease (mother) 0.4 0.5 2.7 -1.0 0.3 -0.7 -0.1 -0.2 0.4 -0.5 -0.1 -0.2 -0.6 -0.6 -0.3 -0.6 -1.2 -1.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.2 0.3 0.9 -0.1 -0.3 -0.7 -0.5 -0.5 -0.1 -0.6 -0.9 -0.5 -0.6 -0.6 -0.6 -0.5 -0.7 0.0
Whole body fat mass 0.2 0.7 3.8 0.9 -0.4 0.3 0.5 -0.0 -1.2 0.4 -0.7 -0.0 0.6 0.6 0.7 0.8 1.2 1.9
Leg fat mass (right) 0.2 0.9 4.4 1.0 -0.7 0.1 0.2 -0.3 -1.6 0.2 -0.5 -0.3 0.4 0.4 0.4 0.8 1.7 2.1
Arm predicted mass (right) 2.9 14.7 23.7 -2.7 4.4 3.3 4.3 4.1 2.0 4.4 -4.7 4.5 4.0 4.0 4.0 4.9 0.3 3.1
Pulse rate, automated reading 8.8 28.5 40.2 5.0 -6.1 -5.7 -6.3 -5.9 -3.0 -6.2 2.7 -6.2 -6.0 -6.0 -5.7 -6.0 2.8 -4.2
Alcohol intake frequency. 0.1 0.3 2.3 -0.4 0.1 0.1 -0.2 0.1 -0.6 -0.1 0.3 0.1 -0.4 -0.4 0.1 -0.7 -0.4 -1.5
Comparative height size at age 10 3.1 16.8 23.8 -2.9 4.9 4.9 4.6 4.8 2.4 4.8 -4.3 4.6 4.4 4.4 4.3 4.3 -0.7 2.8
Number of full sisters 0.9 1.1 3.6 -0.8 0.5 1.0 1.4 0.6 1.3 1.1 0.9 0.9 1.2 1.2 1.9 0.1 -1.0 -0.7
Suffer from ‘nerves’ 1.4 2.2 8.3 -2.0 2.3 0.5 1.2 1.7 2.9 1.3 -1.0 1.9 0.8 0.8 0.7 1.1 -1.2 -0.4
Overall health rating 1.2 2.6 5.6 -2.4 2.2 1.1 1.7 1.8 1.7 1.6 -1.6 1.8 1.1 1.1 1.4 1.6 -1.6 0.5
Chest pain or discomfort 0.3 0.4 1.1 -0.2 1.0 0.4 0.7 0.9 -0.1 0.6 -0.6 0.8 0.4 0.4 0.3 1.1 -0.2 0.8
Had major operations 0.7 0.8 5.1 -1.2 0.4 -0.4 -0.2 0.1 0.6 -0.2 -0.5 0.1 -0.5 -0.5 -0.2 -1.2 -1.7 -2.3
Age at last live birth 2.1 3.0 6.9 1.5 -1.4 -2.6 -2.2 -1.4 -1.5 -1.9 1.3 -1.7 -2.1 -2.1 -2.2 -1.6 0.8 -0.6
Family relationship satisfaction 0.7 0.8 3.1 -0.7 1.3 0.4 0.7 1.0 1.0 0.7 -1.8 0.6 0.4 0.4 0.0 1.2 -0.3 1.3
Leg pain on walking 0.7 0.9 7.1 -0.9 0.8 0.2 0.4 0.5 1.8 0.4 0.2 0.5 0.4 0.4 0.4 -0.0 -2.7 -0.3
Qualifications: NVQ or HND or HNC or equivalent 0.5 0.6 2.8 0.8 -0.7 0.3 -0.2 -0.5 -1.7 -0.0 -1.3 -0.7 0.1 0.1 -0.1 0.4 0.5 1.6
Commuting to job workplace: Car/motor vehicle 0.1 0.2 1.1 0.0 0.1 0.0 -0.0 0.2 1.1 0.1 -0.7 0.1 0.2 0.2 -0.0 -0.0 -0.8 0.1
Illness, injury, bereavement, stress in last 2 years 0.2 0.3 1.5 -1.2 0.4 -0.5 0.2 0.5 0.4 0.1 -0.7 0.7 0.1 0.1 -0.0 0.6 0.2 0.4
Medication: Aspirin 0.3 0.4 1.6 1.3 -0.9 -0.2 -0.3 -0.9 -1.0 -0.4 0.8 -0.6 -0.0 -0.0 0.1 -0.6 0.4 -0.7
Supplements: Vitamin C 0.1 0.1 0.9 0.0 0.1 -0.0 -0.3 0.1 -0.8 -0.0 -0.0 0.0 -0.1 -0.1 -0.3 0.2 -1.0 0.3
Knee pain experienced in last month 0.2 0.4 2.8 -0.9 0.7 -0.2 0.2 0.5 0.2 0.3 0.0 0.7 -0.1 -0.1 0.2 -0.0 -1.7 -0.6
Hypertension (Self-reported) 0.2 0.6 3.0 1.7 -0.9 -0.6 -0.3 -0.8 -1.4 -0.6 -0.0 -0.6 -0.4 -0.4 -0.4 0.1 0.8 1.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.3 0.4 1.3 -0.4 0.2 -0.7 -0.5 -0.3 -0.1 -0.7 -0.5 -0.3 -1.1 -1.1 -1.1 -0.1 0.4 0.4
Illnesses of father: Heart disease 2.7 3.8 5.6 1.5 -2.0 -2.1 -2.3 -2.0 -1.3 -2.3 1.8 -2.1 -2.4 -2.4 -2.2 -2.3 -0.0 -0.6
Illnesses of siblings: Diabetes 1.0 1.2 3.1 1.2 -1.1 -1.1 -0.8 -1.5 -1.8 -1.1 0.6 -1.4 -0.9 -0.9 -0.7 -1.2 -0.6 0.0
Smoking status: Previous 0.6 1.0 2.1 -0.4 0.8 1.0 1.4 0.8 0.8 1.1 -1.3 0.6 1.2 1.2 1.4 1.1 -0.2 0.7
Forced expiratory volume in 1-second (FEV1), predicted 4.8 9.9 15.4 -2.5 3.9 3.1 3.6 3.6 2.4 3.6 -2.8 3.5 3.2 3.2 3.3 3.9 0.1 2.6
Whole body fat-free mass 3.1 17.5 26.9 -3.2 4.9 3.7 4.7 4.7 2.2 4.8 -4.8 5.0 4.3 4.3 4.2 5.2 0.1 3.4
Leg fat-free mass (right) 2.3 12.4 18.7 -3.0 4.2 3.0 3.9 3.9 1.8 4.0 -4.3 4.2 3.5 3.5 3.5 4.3 0.1 2.9
Arm fat percentage (left) 0.5 1.9 4.0 1.8 -2.0 -1.1 -1.1 -1.6 -2.0 -1.2 0.8 -1.7 -0.8 -0.8 -0.8 -0.9 1.7 1.0
Average weekly red wine intake 2.0 3.0 8.4 2.9 -2.1 -1.3 -1.7 -2.0 -1.4 -1.8 0.6 -2.2 -1.4 -1.4 -1.4 -1.4 2.1 0.1
Handedness (chirality/laterality): Left-handed 0.5 0.6 1.0 -0.1 1.0 0.9 1.0 1.0 0.5 0.9 0.8 1.0 0.9 0.9 0.8 0.7 -0.4 0.3
Mood swings 0.1 0.1 0.6 -0.4 0.4 -0.5 0.5 0.2 0.8 0.0 -0.1 -0.0 -0.2 -0.2 0.3 0.4 0.5 -0.0
Loneliness, isolation 0.5 0.6 2.2 0.7 -0.5 -1.0 -0.5 -0.8 -0.6 -0.6 -1.5 -0.8 -1.0 -1.0 -0.6 -0.1 0.5 0.6
Long-standing illness, disability or infirmity 0.5 0.8 8.5 -0.6 0.9 0.1 0.1 0.5 1.0 0.3 -2.9 0.5 -0.3 -0.3 -0.0 0.1 -0.3 0.0
Ever had bowel cancer screening 0.8 1.0 3.6 -1.9 1.2 0.0 0.3 0.9 1.8 0.5 -1.2 1.1 0.0 0.0 -0.1 0.5 -1.6 -0.3
Diabetes diagnosed by doctor 0.3 0.4 1.1 0.4 -1.0 -0.6 -0.7 -0.8 -0.4 -0.6 -1.1 -0.7 -0.6 -0.6 -0.7 -0.7 -0.3 -0.2
Ever had stillbirth, spontaneous miscarriage or termination 0.7 0.8 2.3 0.8 0.0 1.3 0.5 0.4 -1.0 1.0 0.0 0.2 1.3 1.3 0.7 0.6 1.5 0.9
Friendships satisfaction 0.5 0.6 1.4 -0.3 0.9 0.2 0.9 1.1 0.7 0.7 -0.6 0.5 0.7 0.7 0.5 1.2 0.4 1.2
Qualifications: nursing, teaching 0.7 1.0 2.2 0.5 -0.8 -1.0 -0.9 -1.0 -1.5 -1.3 -0.0 -1.0 -1.3 -1.3 -1.1 -0.2 1.4 0.6
Commuting to job workplace: Walk 0.7 0.7 4.2 -0.9 0.1 -1.1 -0.5 -0.1 0.1 -0.6 0.7 -0.1 -1.0 -1.0 -0.6 -1.1 -0.5 -2.1
Eye problems/disorders: Cataract 2.6 3.1 6.4 0.9 -1.6 -2.5 -1.9 -1.7 -0.7 -1.9 -0.2 -2.0 -2.1 -2.1 -1.8 -2.3 0.6 -1.9
Mouth/teeth dental problems: Mouth ulcers 0.5 0.8 2.7 1.0 0.8 0.3 0.8 0.9 0.5 0.8 -0.9 0.8 0.9 0.9 0.5 1.6 1.1 1.1
Medication for cholesterol 0.2 0.3 0.9 -0.9 0.6 0.4 0.5 0.9 0.3 0.5 0.4 0.4 0.4 0.4 0.3 0.6 -0.1 -0.3
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.6 0.7 1.8 1.4 -1.0 -0.5 -0.7 -0.7 -1.1 -1.0 -0.1 -0.9 -0.8 -0.8 -0.7 -0.5 0.8 -0.0
Back pain experienced in last month 2.2 3.2 4.7 -0.8 2.2 1.7 2.1 2.1 1.6 2.0 -1.0 2.0 1.8 1.8 2.1 2.2 0.1 1.7
Mineral and other dietary supplements 0.6 0.8 2.6 0.8 -0.0 1.4 0.6 0.2 0.1 0.7 -0.4 -0.1 0.9 0.9 0.8 0.9 1.5 1.6
Breast cancer (self-reported) 5.6 6.6 11.1 -2.4 3.3 2.6 2.8 3.2 2.5 2.8 -2.1 3.2 2.5 2.5 2.6 2.4 -1.7 1.0
Asthma (self-reported) 0.9 1.8 4.1 -2.0 1.6 1.4 1.5 1.6 0.8 1.5 0.4 1.4 1.3 1.3 1.5 1.1 -1.5 -0.1
Osteoporosis (self-reported) 0.4 0.5 1.5 0.3 -0.7 -0.5 -0.5 -0.3 -0.7 -0.7 1.0 -0.6 -0.8 -0.8 -0.3 -1.1 -0.9 -1.2
Osteoarthritis (self-reported) 1.6 2.1 6.2 -2.2 1.0 -1.7 -0.4 0.5 1.8 -0.6 -1.3 0.8 -1.4 -1.4 -0.9 -0.8 -2.5 -2.3
Medication: Aspirin 0.4 0.5 1.4 1.2 -1.1 -0.2 -0.6 -1.0 -0.9 -0.5 0.8 -0.8 -0.2 -0.2 -0.2 -0.8 0.3 -0.5
Medication: Gliclazide 2.1 2.4 4.8 1.3 -2.2 -1.7 -1.5 -2.1 -1.2 -1.6 1.1 -1.9 -1.5 -1.5 -1.1 -1.6 0.8 -1.3
Illnesses of father: None of the above (group 1) 0.2 0.3 1.6 0.5 -0.3 -0.1 -0.3 -0.2 -0.2 -0.2 -1.3 -0.1 -0.2 -0.2 -0.4 0.2 1.2 0.3
Smoking status: Current 1.0 1.6 4.8 -0.8 1.0 2.2 1.2 1.1 -0.1 1.4 -1.8 1.0 1.6 1.6 1.2 1.3 -0.3 0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.1 0.2 0.7 0.2 0.1 -0.6 -0.4 -0.0 0.0 -0.3 -0.1 -0.1 -0.3 -0.3 -0.3 -0.8 -0.2 -0.8
Whole body water mass 3.0 17.2 26.2 -3.3 4.9 3.7 4.6 4.7 2.2 4.8 -4.8 4.9 4.3 4.3 4.1 5.1 -0.1 3.3
Leg predicted mass (right) 2.4 12.9 19.2 -3.1 4.3 3.1 4.0 4.0 1.9 4.0 -4.3 4.3 3.6 3.6 3.5 4.4 -0.0 2.9
Arm fat mass (left) 0.1 0.5 3.1 0.6 -0.3 0.0 0.3 -0.1 -0.9 0.2 -0.9 0.0 0.4 0.4 0.5 0.7 1.1 1.8
Number of self-reported non-cancer illnesses 1.5 2.6 5.2 0.4 -0.9 -2.0 -1.8 -1.4 -0.2 -1.9 -0.6 -1.3 -2.3 -2.3 -2.3 -1.8 -0.9 -1.6
Average weekly champagne plus white wine intake 0.6 0.8 3.0 -0.9 -0.3 -0.8 -0.9 -0.5 -0.0 -0.9 -0.3 -0.1 -1.0 -1.0 -0.9 -0.9 -1.3 -1.7
Miserableness 0.1 0.2 1.1 -0.2 0.7 0.1 0.4 0.7 -0.1 0.3 -1.1 0.1 0.0 0.0 0.1 0.4 -0.6 0.3
Guilty feelings 0.2 0.3 0.7 -0.5 0.7 -0.5 0.5 0.4 0.8 0.3 -0.8 0.5 0.1 0.1 0.4 0.8 -0.1 0.6
Wears glasses or contact lenses 0.6 0.7 2.5 -1.1 0.6 0.7 0.8 0.9 -0.4 0.7 1.1 0.6 0.7 0.7 1.1 -0.4 -0.0 -1.6
Ever taken oral contraceptive pill 1.4 1.5 2.8 1.4 -1.6 -1.3 -1.3 -1.6 -1.1 -1.4 0.5 -1.7 -1.3 -1.3 -1.1 -1.1 0.7 -0.1
Hearing aid user 0.6 0.7 3.4 -0.9 0.2 -0.6 -0.6 0.0 0.2 -0.2 -0.8 0.2 -0.5 -0.5 -0.4 -0.9 -1.8 -1.7
Mother’s age at death 0.7 0.9 2.4 -0.8 0.1 -1.4 -0.7 -0.3 1.1 -0.7 0.1 -0.3 -1.0 -1.0 -1.0 -0.9 -1.3 -1.5
Financial situation satisfaction 0.3 0.4 1.3 -1.1 1.0 -0.5 0.3 0.9 1.0 0.4 -0.1 0.6 -0.1 -0.1 0.3 0.3 -0.5 -0.3
Tinnitus: Yes, now most or all of the time 0.5 0.6 2.3 -0.0 -0.4 -0.7 -0.2 -0.5 1.4 -0.4 -1.0 -0.4 -0.6 -0.6 0.1 -1.3 -0.7 -1.5
Commuting to job workplace: Public transport 3.1 3.7 6.7 1.2 -1.8 -2.0 -2.1 -1.7 -1.2 -2.2 2.4 -1.6 -2.1 -2.1 -2.0 -2.2 0.7 -2.6
Eye problems/disorders: Glaucoma 0.5 0.6 2.8 -0.5 0.1 -0.6 -0.3 -0.1 1.7 -0.6 -0.7 -0.3 -0.7 -0.7 -0.8 -0.4 -1.2 -0.9
Medication: Blood pressure 0.1 0.1 0.5 0.7 -0.3 0.4 0.3 -0.4 -0.4 0.2 -0.2 0.1 0.3 0.3 0.4 -0.1 0.7 0.3
Pain type(s) experienced in last month: Hip pain 0.1 0.2 1.7 -0.3 0.0 -0.4 -0.4 0.0 -0.2 -0.1 -1.3 -0.1 -0.2 -0.2 -0.3 -0.4 -0.2 -0.1
Supplements: Fish oil (including cod liver oil) 0.2 0.3 1.5 -0.4 0.2 -0.6 -0.3 0.0 0.2 -0.1 0.9 0.5 -0.2 -0.2 -0.3 -0.8 -0.9 -1.2
High cholesterol (Self-reported) 1.6 2.8 5.7 0.5 -1.8 -2.4 -2.0 -2.0 -0.3 -1.9 -0.2 -1.8 -2.0 -2.0 -2.0 -1.9 -0.6 -1.3
Medication: Bendroflumethiazide 0.2 0.4 2.0 0.4 0.2 0.4 0.2 0.2 0.5 0.3 -1.4 0.4 0.4 0.4 -0.1 0.5 -0.3 1.4
Medication: Paracetamol 0.2 0.2 1.0 -0.4 0.5 0.3 0.2 0.4 1.0 0.2 -0.9 0.3 -0.0 -0.0 0.2 0.1 -0.7 -0.5
Medication: Lisinopril 0.1 0.2 0.4 -0.5 0.4 -0.1 0.3 0.2 -0.2 0.4 0.5 0.6 0.4 0.4 0.2 0.5 0.6 0.6
Medication: Atorvastatin 0.7 0.8 1.8 -1.4 1.1 0.4 0.8 1.1 1.2 0.9 -0.9 1.0 0.7 0.7 0.7 0.4 -1.1 -0.0
Illnesses of father: High blood pressure 0.3 0.3 1.9 -1.0 -0.1 0.1 -0.0 -0.1 0.2 -0.1 1.0 -0.0 0.0 0.0 0.2 -0.7 -0.9 -1.4
Alcohol drinker status: Never 0.2 0.2 0.8 0.0 -0.1 -0.4 -0.7 -0.3 -0.7 -0.5 -0.1 0.0 -0.6 -0.6 -0.9 -0.6 0.5 -0.4
Ever smoked 1.1 1.9 3.6 -0.4 0.9 1.9 1.5 1.0 0.8 1.5 -1.8 0.8 1.8 1.8 1.6 1.5 0.9 1.4
Basal metabolic rate 2.5 13.9 22.1 -2.7 4.2 3.3 4.2 4.1 1.8 4.3 -4.4 4.3 3.9 3.9 3.8 4.7 0.3 3.4
Leg fat percentage (left) 0.5 1.7 4.3 1.7 -2.1 -1.1 -1.2 -1.6 -1.8 -1.2 0.4 -1.7 -0.9 -0.9 -0.8 -0.9 1.3 0.7
Arm fat-free mass (left) 2.6 13.0 20.4 -2.8 4.2 3.1 4.0 3.9 2.0 4.1 -4.5 4.3 3.7 3.7 3.6 4.5 -0.2 2.9
Number of operations (self-reported) 2.4 3.5 7.3 -2.7 2.5 1.5 1.7 2.1 1.5 1.9 -2.5 2.4 1.6 1.6 1.5 1.4 -1.5 0.4
Average weekly beer plus cider intake 0.6 0.9 2.1 0.1 -0.7 -1.4 -1.1 -1.1 0.0 -1.0 -0.6 -1.0 -1.2 -1.2 -1.2 -0.9 0.3 0.7
Irritability 0.7 1.1 6.9 0.2 -0.3 -1.3 -0.7 -0.4 1.0 -0.9 -2.6 -0.9 -1.2 -1.2 -1.2 -0.4 -1.0 0.4
Risk taking 0.3 0.5 0.9 -0.1 -0.6 -0.4 -0.9 -0.6 0.6 -0.8 -0.5 -0.9 -0.9 -0.9 -0.8 -0.7 0.7 -0.5
Ever had prostate specific antigen (PSA) test 0.6 0.7 2.7 -1.1 0.1 -0.8 -0.2 -0.2 1.0 -0.3 -0.6 -0.3 -0.7 -0.7 -0.2 -0.8 -1.7 -1.5
Fractured/broken bones in last 5 years 0.4 0.5 2.9 0.6 0.2 -0.3 -0.3 0.1 1.7 -0.1 -0.6 -0.0 -0.3 -0.3 -0.4 -0.5 1.3 -1.1
Age started oral contraceptive pill 1.4 1.7 9.0 0.2 -0.2 -1.6 -1.0 -0.5 0.6 -1.0 1.8 -0.3 -1.4 -1.4 -1.0 -1.5 0.8 -3.0
Diastolic blood pressure, automated reading 2.4 7.5 12.4 -2.4 3.3 2.7 3.4 3.0 1.3 2.9 -2.2 3.5 2.8 2.8 3.0 3.5 -0.4 1.8
Ever depressed for a whole week 0.3 0.3 3.3 -0.2 0.6 -0.2 0.3 0.3 -0.0 0.0 -1.8 0.4 -0.2 -0.2 -0.1 0.3 -0.5 0.5
Unable to work because of sickness or disability 0.1 0.2 1.1 -0.2 0.4 0.4 0.2 0.2 -0.1 0.0 -0.3 0.3 0.1 0.1 -0.2 0.6 -0.7 1.0
Commuting to job workplace: Cycle 2.3 2.7 6.7 -2.6 2.4 0.7 1.6 2.1 1.7 1.8 -0.0 2.5 1.4 1.4 1.3 1.6 0.1 -0.7
Myopia 0.4 0.6 3.7 0.1 -0.4 -0.8 -0.2 -0.5 0.3 -0.4 1.1 -0.3 -0.5 -0.5 0.2 -1.1 -1.1 -1.9
Vascular/heart problems diagnosed by doctor 0.3 0.7 3.4 -1.8 1.2 0.8 0.5 1.0 1.1 0.8 -0.4 0.8 0.6 0.6 0.5 0.2 -0.5 -0.4
Cholesterol lowering medication 0.7 1.1 2.2 -0.0 -0.6 -1.5 -1.2 -1.2 0.2 -1.1 -0.8 -0.7 -1.5 -1.5 -1.3 -1.2 0.3 -0.8
Medication: Omeprazole (e.g. Zanprol) 0.3 0.4 2.7 -0.8 0.3 -0.5 -0.1 0.0 1.1 -0.4 -0.2 -0.1 -0.7 -0.7 -0.5 -0.1 -1.6 -0.4
Pain experienced in last month 0.9 1.5 2.8 1.0 -1.7 -1.4 -1.5 -1.6 -1.0 -1.3 1.3 -1.4 -0.9 -0.9 -1.3 -1.5 0.6 -0.7
Supplements: Calcium 0.6 0.7 1.3 -0.5 0.8 0.7 0.9 0.9 0.8 0.9 -0.6 0.8 0.7 0.7 0.9 1.1 -0.6 1.1
Basal cell carcinoma (self-reported) 0.2 0.2 1.6 0.6 -0.2 -0.3 -0.4 -0.3 0.2 -0.6 1.3 0.0 -0.5 -0.5 -0.5 -0.4 -0.1 0.2
Heart attack/myocardial infarction (self-reported) 0.3 0.3 0.6 0.7 -0.8 -0.7 -0.7 -0.6 -0.7 -0.6 0.4 -0.5 -0.5 -0.5 -0.6 -0.4 -0.4 0.3
Deep venous thrombosis (DVT) (self-reported) 0.1 0.2 0.8 -0.6 0.5 0.1 0.0 -0.1 -0.7 -0.0 -0.9 -0.1 -0.3 -0.3 -0.2 -0.6 -0.1 0.1
Heart disease (siblings) 0.7 0.9 2.9 0.4 -0.6 -1.7 -1.1 -0.9 -0.6 -1.2 -0.1 -0.9 -1.1 -1.1 -1.4 -0.5 0.6 0.3
Alcohol drinker status: Previous 0.5 0.5 1.5 -1.1 1.1 0.6 0.7 0.8 0.0 0.6 -0.5 1.1 0.2 0.2 0.7 0.4 -1.2 -0.2
Pack years of smoking 0.7 1.1 2.2 -1.1 1.0 0.7 1.0 0.7 1.1 0.9 -1.5 1.3 0.9 0.9 1.1 0.5 -1.1 -1.2
Impedance of whole body 0.9 4.4 11.3 3.4 -3.0 -1.0 -2.1 -2.3 -1.8 -2.3 2.1 -2.8 -1.5 -1.5 -1.5 -2.5 0.7 -0.5
Leg fat mass (left) 0.1 0.6 3.1 0.7 -0.4 0.1 0.3 -0.1 -1.1 0.3 -0.8 -0.1 0.4 0.4 0.5 0.8 1.3 1.8
Arm predicted mass (left) 2.7 13.6 22.8 -2.9 4.3 3.0 4.1 4.0 2.1 4.2 -4.8 4.4 3.7 3.7 3.7 4.6 -0.3 2.9