TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Whole body fat-free mass
:
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chr17:4,488,884-6,031,861
Best TWAS P=1.61e-08 · Best GWAS P=1.46e-07 conditioned to 0.159
4.4M
4.6M
4.8M
5M
5.2M
5.4M
5.6M
5.8M
6M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Glioblastoma Multiforme
RABEP1
0.23
0.13
blup
79
0.15
3.4e-05
4.5
-5.7
1.6e-08
-0.77
0.05
0.84
TRUE
2
ROSMAP
Brain Pre-frontal Cortex
RPAIN
0.06
0.06
lasso
3
0.06
3.1e-08
5.2
-5.4
5.6e-08
-0.98
0.00
1.00
FALSE
1
GTEx
Esophagus Gastroesophageal Junction
RABEP1
0.19
-0.01
lasso
13
0.00
4.2e-01
4.4
-5.3
1.0e-07
-0.82
0.03
0.77
FALSE
3
The Cancer Genome Atlas
Glioblastoma Multiforme
NUP88
0.12
0.07
enet
12
0.09
1.2e-03
4.4
-5.3
1.3e-07
-0.78
0.02
0.64
FALSE