[Hub]/) : Traits : Whole body fat-free mass :

chr2:35,883,253-37,567,226

Best TWAS P=2.05e-11 · Best GWAS P=4.08e-10 conditioned to 0.0144

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex FEZ2 0.16 0.24 lasso 2 0.22 1.3e-26 6.1 -6.1 1.1e-09 -0.97 0.00 1.00 FALSE
2 GTEx Adipose Subcutaneous AC007401.1 0.10 0.02 lasso 4 0.02 5.4e-03 5.5 6.1 1.3e-09 0.87 0.02 0.96 FALSE
3 GTEx Artery Tibial CRIM1 0.10 0.04 lasso 4 0.05 1.4e-04 5.5 -6.3 3.2e-10 -0.86 0.02 0.98 FALSE
4 GTEx Artery Tibial RP11-78I14.1 0.10 0.08 enet 16 0.07 4.2e-06 5.5 -6.1 1.4e-09 -0.71 0.09 0.87 FALSE
5 GTEx Brain Cerebellar Hemisphere CRIM1 0.36 0.21 lasso 5 0.16 5.4e-05 5.5 5.6 1.9e-08 0.85 0.05 0.87 FALSE
6 GTEx Brain Cerebellar Hemisphere FEZ2 0.41 0.30 lasso 6 0.28 8.6e-08 5.1 5.3 1.4e-07 0.89 0.04 0.95 FALSE
7 GTEx Brain Cerebellar Hemisphere AC007401.1 0.40 0.26 lasso 4 0.22 2.3e-06 5.5 5.3 8.9e-08 0.87 0.06 0.92 FALSE
8 GTEx Brain Cerebellar Hemisphere RP11-490M8.1 0.37 0.18 lasso 4 0.15 1.2e-04 5.1 5.3 1.4e-07 0.90 0.03 0.88 FALSE
9 GTEx Brain Cerebellum AC007401.1 0.27 0.21 enet 5 0.20 1.5e-06 5.5 5.5 2.9e-08 0.86 0.08 0.88 FALSE
10 GTEx Brain Cerebellum RP11-490M8.1 0.21 0.21 lasso 4 0.20 1.4e-06 5.2 5.3 1.3e-07 0.82 0.05 0.92 FALSE
11 GTEx Spleen FEZ2 0.42 0.16 enet 25 0.17 3.9e-05 5.2 6.7 2.1e-11 0.66 0.04 0.89 TRUE
12 GTEx Whole Blood AC007401.1 0.06 0.06 lasso 5 0.05 4.6e-05 5.1 5.4 7.0e-08 0.89 0.12 0.85 FALSE
13 NTR Blood CRIM1 0.09 0.10 lasso 6 0.11 3.1e-32 5.2 -5.3 1.3e-07 -0.91 0.15 0.85 FALSE
14 ROSMAP Brain Pre-frontal Cortex FEZ2 0.41 0.55 lasso 5 0.58 3.1e-93 5.4 -5.5 4.0e-08 -0.93 0.23 0.77 FALSE
15 The Cancer Genome Atlas Breast Invasive Carcinoma FEZ2 0.01 0.01 blup 85 0.01 1.0e-03 5.1 -6.3 3.5e-10 -0.90 0.01 0.96 FALSE
16 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma FEZ2 0.06 0.05 lasso 4 0.04 3.3e-03 5.5 -5.4 7.4e-08 -0.92 0.04 0.82 FALSE
17 The Cancer Genome Atlas Prostate Adenocarcinoma FEZ2 0.06 0.05 blup 87 0.08 1.4e-08 5.4 -5.8 6.9e-09 -0.91 0.07 0.93 FALSE