[Hub]/) : Traits : Whole body fat-free mass : ← →

chr3:183,204,923-186,072,370

Best TWAS P=4.48e-23 · Best GWAS P=8.64e-24 conditioned to 0.00405

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
19	The Cancer Genome Atlas	Lung Adenocarcinoma	PSMD2	0.09	0.02	blup	50	0.05	1.2e-06	-9.4	9.9	4.5e-23	-0.73	0.03	0.84	TRUE
16	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ETV5	0.03	0.01	blup	55	0.02	1.3e-03	-7.2	-7.0	2.0e-12	-0.04	0.01	0.86	TRUE
18	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	ABCF3	0.08	0.03	blup	51	0.06	6.1e-04	2.6	5.6	2.6e-08	-0.25	0.02	0.69	TRUE
2	CommonMind	Brain Pre-frontal Cortex	SENP2	0.21	0.18	enet	33	0.19	4.2e-22	-5.2	5.5	4.5e-08	0.02	1.00	0.00	TRUE
22	The Cancer Genome Atlas	Testicular Germ Cell Tumors	VWA5B2	0.10	0.04	blup	51	0.04	1.8e-02	5.7	-8.6	1.1e-17	0.43	0.03	0.33	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ECE2	0.24	0.20	bslmm	542	0.19	1.6e-22	8.2	8.0	1.0e-15	-0.37	1.00	0.00	FALSE
17	The Cancer Genome Atlas	Brain Lower Grade Glioma	ECE2	0.04	0.02	blup	61	0.03	3.5e-04	8.2	7.5	4.6e-14	-0.24	0.54	0.02	FALSE
10	GTEx	Skin Sun Exposed Lower leg	ABCF3	0.13	0.08	lasso	4	0.11	1.6e-09	5.8	7.3	2.2e-13	-0.36	0.98	0.01	FALSE
8	GTEx	Pituitary	ECE2	0.52	0.30	lasso	7	0.23	1.5e-06	8.2	7.0	3.6e-12	-0.31	0.39	0.23	FALSE
21	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	PSMD2	0.05	0.00	enet	10	0.01	3.6e-02	8.2	6.5	6.8e-11	-0.49	0.01	0.10	FALSE
4	GTEx	Brain Putamen basal ganglia	ECE2	0.38	0.03	enet	22	0.11	1.4e-03	8.2	6.5	8.8e-11	-0.28	0.08	0.16	FALSE
3	GTEx	Artery Tibial	PSMD2	0.13	0.09	lasso	5	0.08	1.3e-06	-6.1	6.3	2.4e-10	-0.42	0.88	0.02	FALSE
11	GTEx	Skin Sun Exposed Lower leg	PSMD2	0.13	0.14	lasso	4	0.15	1.4e-12	-6.1	6.2	5.8e-10	-0.39	1.00	0.00	FALSE
12	YFS	Blood	PSMD2	0.26	0.22	lasso	5	0.24	2.4e-77	-6.1	5.8	5.2e-09	-0.39	1.00	0.00	FALSE
5	GTEx	Esophagus Mucosa	ABCF3	0.11	0.10	lasso	3	0.08	3.6e-06	-5.3	5.6	2.8e-08	-0.31	0.37	0.54	FALSE
15	The Cancer Genome Atlas	Colon Adenocarcinoma	ABCF3	0.07	0.00	blup	51	0.01	4.4e-02	5.7	5.5	3.7e-08	-0.26	0.01	0.88	FALSE
7	GTEx	Pancreas	ECE2	0.26	0.04	enet	24	0.09	1.2e-04	8.2	5.5	4.5e-08	-0.24	0.16	0.09	FALSE
13	The Cancer Genome Atlas	Breast Invasive Carcinoma	PSMD2	0.03	0.03	blup	50	0.03	4.8e-06	-6.1	5.5	4.6e-08	-0.48	0.66	0.27	FALSE
20	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CAMK2N2	0.04	0.01	enet	8	0.03	3.9e-04	2.9	5.3	1.3e-07	-0.32	0.14	0.06	FALSE
14	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	VWA5B2	0.15	0.00	blup	52	0.01	1.4e-01	3.9	5.3	1.4e-07	-0.16	0.01	0.04	FALSE
9	GTEx	Skin Not Sun Exposed Suprapubic	ABCF3	0.15	0.10	lasso	4	0.11	1.1e-06	5.8	5.2	1.9e-07	-0.26	0.77	0.04	FALSE
6	GTEx	Lung	PSMD2	0.17	0.11	lasso	2	0.10	6.4e-08	-6.1	5.1	2.8e-07	-0.40	0.98	0.00	FALSE