[Hub]/) : Traits : Whole body water mass :

chr9:97,520,168-100,366,953

Best TWAS P=2.26e-22 · Best GWAS P=2.65e-26 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex LOC441454 0.05 0.01 lasso 3 0.02 1.5e-03 6.05 6.7 1.7e-11 0.04 0.04 0.55 FALSE
2 GTEx Adipose Subcutaneous HSD17B3 0.21 0.01 enet 31 0.04 1.9e-04 6.13 5.1 2.8e-07 0.09 0.32 0.21 FALSE
3 GTEx Artery Tibial RP11-435O5.5 0.09 0.04 lasso 2 0.02 7.3e-03 9.98 -9.7 2.3e-22 -0.95 0.01 0.94 TRUE
4 GTEx Breast Mammary Tissue CDC14B 0.16 0.02 enet 21 0.02 3.7e-02 8.30 -7.1 1.0e-12 -0.02 0.06 0.86 FALSE
5 GTEx Cells EBV-transformed lymphocytes AAED1 0.17 0.02 lasso 3 0.04 2.4e-02 8.28 7.4 1.6e-13 0.02 0.05 0.51 FALSE
6 GTEx Cells Transformed fibroblasts RP11-435O5.5 0.14 0.04 lasso 4 0.02 7.9e-03 5.16 -5.4 8.6e-08 -0.60 0.36 0.03 TRUE
7 GTEx Heart Atrial Appendage RP11-435O5.4 0.18 0.00 lasso 5 0.00 6.2e-01 2.67 -5.2 1.6e-07 -0.10 0.04 0.44 TRUE
8 GTEx Liver PTCH1 0.25 0.06 enet 11 0.03 4.9e-02 9.65 6.2 4.7e-10 0.26 0.16 0.06 FALSE
9 GTEx Nerve Tibial HSD17B3 0.14 0.00 enet 20 0.00 2.4e-01 8.03 6.3 3.6e-10 0.05 0.08 0.40 FALSE
10 GTEx Nerve Tibial ZNF367 0.10 0.05 lasso 3 0.02 7.9e-03 8.65 7.8 5.5e-15 0.04 0.02 0.97 FALSE
11 GTEx Spleen PTCH1 0.33 0.08 lasso 8 0.18 1.9e-05 -0.26 5.5 4.3e-08 0.28 0.17 0.10 TRUE
12 GTEx Testis HABP4 0.19 0.22 lasso 9 0.21 1.1e-09 8.37 8.4 5.5e-17 0.04 0.07 0.93 FALSE
13 GTEx Thyroid CDC14B 0.15 0.10 lasso 5 0.08 5.3e-07 7.97 -8.1 6.6e-16 -0.04 0.24 0.75 FALSE
14 NTR Blood PTCH1 0.04 0.02 blup 433 0.02 4.1e-08 7.11 6.0 1.9e-09 0.09 0.97 0.01 TRUE
15 YFS Blood HABP4 0.08 0.09 enet 24 0.11 5.9e-34 8.46 -8.1 6.1e-16 -0.09 0.03 0.97 FALSE
16 YFS Blood PTCH1 0.09 0.05 lasso 8 0.05 1.2e-15 7.08 7.8 4.4e-15 0.42 0.99 0.01 FALSE
17 The Cancer Genome Atlas Breast Invasive Carcinoma CDC14B 0.02 0.01 lasso 1 0.01 3.0e-03 8.53 -8.5 1.5e-17 -0.04 0.03 0.57 FALSE
18 The Cancer Genome Atlas Glioblastoma Multiforme CDC14B 0.16 0.17 blup 41 0.19 2.6e-06 8.28 -7.5 4.7e-14 -0.01 0.05 0.92 FALSE
19 The Cancer Genome Atlas Glioblastoma Multiforme HABP4 0.08 0.06 blup 44 0.05 1.6e-02 7.85 -8.6 5.6e-18 -0.06 0.03 0.49 FALSE
20 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma HABP4 0.02 0.02 blup 44 0.02 7.1e-03 8.28 8.6 1.1e-17 0.04 0.03 0.66 FALSE
21 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CDC14B 0.03 0.02 blup 42 0.02 2.1e-03 8.28 -8.5 2.2e-17 -0.04 0.04 0.62 FALSE
22 The Cancer Genome Atlas Brain Lower Grade Glioma CDC14B 0.05 0.06 lasso 5 0.06 6.5e-07 8.29 -7.7 1.9e-14 -0.04 0.08 0.92 FALSE
23 The Cancer Genome Atlas Brain Lower Grade Glioma HABP4 0.05 0.08 lasso 5 0.08 6.9e-09 7.82 -8.0 1.1e-15 -0.05 0.11 0.89 FALSE
24 The Cancer Genome Atlas Prostate Adenocarcinoma PTCH1 0.02 0.01 blup 54 0.02 1.1e-03 8.60 -8.5 1.7e-17 -0.86 0.02 0.74 FALSE
25 The Cancer Genome Atlas Stomach Adenocarcinoma CDC14B 0.08 0.02 blup 41 0.04 1.0e-03 6.05 -8.7 2.5e-18 -0.08 0.02 0.59 TRUE
26 The Cancer Genome Atlas Thyroid Carcinoma CDC14B 0.05 0.07 blup 42 0.08 4.8e-08 8.34 -8.3 1.2e-16 -0.03 0.05 0.95 FALSE