[Hub]/) : Traits : Whole body water mass :

chr9:93,476,005-96,338,382

Best TWAS P=5.74e-10 · Best GWAS P=9.42e-11 conditioned to 0.00399

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta ECM2 0.11 0.10 lasso 10 0.09 1.1e-05 -4.5 -5.3 1.1e-07 0.79 0.28 0.71 FALSE
2 GTEx Brain Cerebellum ZNF484 0.21 0.01 lasso 9 0.01 1.7e-01 -6.0 -5.5 3.5e-08 0.79 0.08 0.31 FALSE
3 GTEx Esophagus Mucosa CENPP 0.09 0.01 lasso 5 0.02 2.1e-02 -4.4 5.3 9.2e-08 -0.74 0.15 0.69 FALSE
4 GTEx Esophagus Muscularis BICD2 0.09 0.02 enet 26 0.07 5.0e-05 -4.7 -5.8 5.2e-09 0.57 0.04 0.80 FALSE
5 GTEx Heart Left Ventricle ECM2 0.07 0.05 lasso 3 0.02 3.1e-02 -6.0 -5.8 5.4e-09 0.75 0.06 0.79 FALSE
6 GTEx Skin Sun Exposed Lower leg IPPK 0.17 0.07 enet 8 0.07 2.7e-06 -6.3 5.8 8.4e-09 -0.90 0.02 0.98 FALSE
7 GTEx Testis NFIL3 0.47 0.33 enet 8 0.29 3.8e-13 -6.2 6.2 5.7e-10 0.01 0.00 1.00 TRUE
8 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma IPPK 0.06 0.03 blup 49 0.04 5.8e-03 -6.0 5.8 6.1e-09 -0.88 0.01 0.65 FALSE
9 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma CENPP 0.06 0.02 blup 160 0.04 6.3e-05 -5.6 5.1 2.6e-07 -0.72 0.04 0.92 FALSE
10 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma BICD2 0.10 0.03 blup 52 0.03 1.3e-02 -6.0 -5.4 5.6e-08 0.68 0.03 0.21 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma BICD2 0.06 0.02 blup 52 0.05 2.9e-06 -6.0 -5.8 7.6e-09 0.81 0.03 0.96 FALSE
12 The Cancer Genome Atlas Lung Adenocarcinoma ECM2 0.10 0.04 lasso 2 0.04 4.2e-05 -5.8 -5.9 4.6e-09 0.90 0.00 0.99 TRUE
13 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma IPPK 0.03 0.02 blup 51 0.01 3.2e-02 -5.9 5.8 6.3e-09 -0.87 0.03 0.64 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma IPPK 0.03 0.04 blup 50 0.04 6.7e-05 -5.9 5.7 9.6e-09 -0.94 0.01 0.98 FALSE