[Hub]/) : Traits : Whole body water mass : ← →

chr1:154,238,383-155,910,830

Best TWAS P=4.71e-42 · Best GWAS P=6.88e-39 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Brain Cerebellar Hemisphere	DCST2	0.45	0.10	lasso	6	0.16	6.6e-05	-4.267	9.9	5.6e-23	0.75	0.01	0.96	TRUE
2	GTEx	Brain Nucleus accumbens basal ganglia	DCST2	0.28	0.04	lasso	5	0.13	2.0e-04	13.044	8.3	9.4e-17	0.69	0.02	0.90	TRUE
3	GTEx	Brain Putamen basal ganglia	DCST2	0.56	0.05	enet	11	0.10	2.8e-03	-4.267	5.4	8.3e-08	0.47	0.18	0.58	FALSE
4	GTEx	Breast Mammary Tissue (Female)	FAM189B	0.05	-0.01	lasso	2	0.00	4.8e-01	-6.689	6.7	2.6e-11	0.09	0.04	0.07	FALSE
5	GTEx	Colon Sigmoid	GBAP1	0.16	0.13	enet	8	0.14	8.4e-06	3.296	5.2	2.6e-07	0.09	0.65	0.04	FALSE
6	GTEx	Esophagus Mucosa	ADAM15	0.11	0.02	enet	16	0.04	1.5e-03	-5.778	-6.2	5.2e-10	-0.43	0.13	0.78	FALSE
7	GTEx	Esophagus Mucosa	MUC1	0.17	0.20	lasso	4	0.18	5.6e-12	-7.478	-7.1	1.0e-12	-0.12	1.00	0.00	TRUE
8	GTEx	Pancreas	THBS3	0.36	0.14	lasso	6	0.12	1.0e-05	2.898	-6.1	8.3e-10	-0.34	0.18	0.54	TRUE
9	GTEx	Pancreas	RP11-263K19.4	0.22	0.06	enet	23	0.05	3.1e-03	2.898	-8.6	5.5e-18	-0.43	0.06	0.49	FALSE
10	GTEx	Skin Not Sun Exposed Suprapubic	GBAP1	0.15	0.06	lasso	4	0.06	3.6e-04	-7.567	6.2	4.9e-10	0.11	0.54	0.04	FALSE
11	GTEx	Skin Sun Exposed Lower leg	ADAM15	0.14	0.09	lasso	4	0.08	6.1e-07	13.044	-13.6	4.7e-42	-0.96	0.00	1.00	TRUE
12	GTEx	Spleen	SHC1	0.22	0.14	lasso	2	0.08	4.0e-03	-5.790	-5.5	3.4e-08	-0.15	0.14	0.05	FALSE
13	GTEx	Testis	MUC1	0.20	0.02	lasso	7	0.07	7.5e-04	-7.567	-6.4	1.4e-10	-0.11	0.27	0.05	TRUE
14	GTEx	Thyroid	DCST2	0.16	0.12	lasso	2	0.11	6.4e-09	-4.267	6.3	2.2e-10	0.53	0.38	0.62	FALSE
15	GTEx	Vagina	GBAP1	0.27	0.08	lasso	7	0.17	1.3e-04	-5.790	5.6	2.7e-08	0.09	0.25	0.05	FALSE
16	METSIM	Adipose	DCST2	0.04	0.04	enet	12	0.04	4.3e-07	-4.101	5.7	9.9e-09	0.47	0.86	0.11	TRUE
17	NTR	Blood	ZBTB7B	0.02	0.02	lasso	1	0.01	5.4e-05	7.303	7.3	2.8e-13	0.67	0.87	0.03	FALSE
18	ROSMAP	Brain Pre-frontal Cortex	SLC50A1	0.06	0.02	bslmm	331	0.03	4.3e-05	-7.478	-7.5	6.0e-14	-0.27	0.65	0.04	FALSE
19	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	TRIM46	0.03	0.00	blup	33	0.02	3.6e-03	-7.478	-6.5	6.7e-11	-0.11	0.01	0.68	FALSE
20	The Cancer Genome Atlas	Breast Invasive Carcinoma	LENEP	0.01	0.00	blup	37	0.01	1.6e-03	-3.990	6.0	2.1e-09	0.48	0.02	0.30	FALSE
21	The Cancer Genome Atlas	Breast Invasive Carcinoma	TRIM46	0.03	0.01	blup	32	0.01	4.9e-03	-7.458	-5.4	8.3e-08	-0.11	0.00	0.64	TRUE
22	The Cancer Genome Atlas	Colon Adenocarcinoma	ADAM15	0.15	0.02	blup	49	0.08	1.4e-05	6.568	-6.2	6.1e-10	-0.34	0.03	0.04	TRUE
23	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MUC1	0.04	0.01	enet	4	0.02	1.3e-03	-7.478	-6.4	2.1e-10	-0.15	0.00	0.88	FALSE
24	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	RAG1AP1	0.07	0.00	blup	76	0.00	2.9e-01	-3.066	-6.3	3.3e-10	-0.17	0.02	0.25	FALSE
25	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	ADAM15	0.09	0.00	blup	49	0.02	3.6e-02	0.054	-5.7	1.1e-08	-0.43	0.01	0.09	FALSE
26	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ZBTB7B	0.05	0.06	lasso	2	0.05	1.8e-06	13.044	-13.0	7.4e-39	-1.00	0.00	1.00	FALSE
27	The Cancer Genome Atlas	Prostate Adenocarcinoma	GBA	0.05	0.01	lasso	2	0.01	2.3e-02	6.679	-5.5	3.3e-08	-0.07	0.02	0.04	FALSE