[Hub]/) : Traits : Whole body water mass :

chr4:16,922,182-18,507,692

Best TWAS P=1.81e-57 · Best GWAS P=1.55e-52 conditioned to NaN

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex MED28 0.07 0.09 enet 9 0.11 7.1e-13 -5.11 5.1 2.8e-07 -0.18 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous DCAF16 0.21 0.15 lasso 3 0.17 5.1e-14 9.11 8.9 7.2e-19 -0.24 1.00 0.00 FALSE
3 GTEx Adipose Visceral Omentum DCAF16 0.19 0.06 enet 10 0.11 3.9e-06 9.11 10.2 1.2e-24 -0.35 0.28 0.49 FALSE
4 GTEx Artery Aorta DCAF16 0.10 0.01 enet 6 0.02 4.7e-02 -14.27 16.0 1.8e-57 -0.81 0.05 0.80 TRUE
5 GTEx Artery Tibial DCAF16 0.16 0.16 lasso 5 0.13 1.5e-10 10.49 11.8 6.8e-32 -0.36 1.00 0.00 TRUE
6 GTEx Breast Mammary Tissue DCAF16 0.12 0.08 lasso 4 0.10 6.4e-06 9.12 12.1 7.6e-34 -0.52 0.15 0.63 FALSE
7 GTEx Breast Mammary Tissue (Male) DCAF16 0.24 0.03 enet 18 -0.01 4.4e-01 -13.51 13.4 6.2e-41 -0.76 0.04 0.57 FALSE
8 GTEx Breast Mammary Tissue (Female) DCAF16 0.16 0.13 lasso 2 0.06 7.8e-03 9.11 9.2 3.0e-20 -0.27 0.06 0.08 FALSE
9 GTEx Colon Transverse MED28 0.13 0.05 lasso 3 0.02 5.8e-02 -4.48 5.1 3.1e-07 -0.11 0.20 0.04 FALSE
10 GTEx Esophagus Mucosa DCAF16 0.10 0.02 lasso 4 0.02 8.3e-03 9.12 9.8 1.9e-22 -0.37 0.13 0.41 FALSE
11 GTEx Esophagus Muscularis DCAF16 0.16 0.14 lasso 3 0.14 9.3e-09 9.11 8.9 5.2e-19 -0.27 0.99 0.00 FALSE
12 GTEx Nerve Tibial DCAF16 0.16 0.14 lasso 3 0.14 2.8e-10 9.11 10.5 1.5e-25 -0.37 0.99 0.01 FALSE
13 GTEx Pituitary DCAF16 0.27 0.20 enet 15 0.19 1.3e-05 9.11 9.2 5.1e-20 -0.38 0.07 0.35 FALSE
14 GTEx Skin Not Sun Exposed Suprapubic DCAF16 0.16 0.08 lasso 5 0.12 4.4e-07 10.12 11.1 8.6e-29 -0.35 0.64 0.04 TRUE
15 GTEx Skin Sun Exposed Lower leg DCAF16 0.14 0.12 enet 14 0.12 5.4e-10 9.12 10.3 9.6e-25 -0.28 1.00 0.00 FALSE
16 GTEx Spleen DCAF16 0.35 0.02 lasso 5 0.11 8.5e-04 9.11 14.2 5.2e-46 -0.66 0.06 0.53 FALSE
17 GTEx Stomach DCAF16 0.21 0.04 lasso 6 0.02 5.6e-02 10.26 11.3 1.6e-29 -0.26 0.19 0.04 FALSE
18 GTEx Thyroid DCAF16 0.11 0.02 lasso 5 0.03 2.3e-03 9.11 13.4 8.6e-41 -0.54 0.17 0.70 FALSE
19 ROSMAP Brain Pre-frontal Cortex FAM184B 0.17 0.14 enet 31 0.18 5.1e-23 -5.11 -7.1 1.6e-12 0.26 1.00 0.00 FALSE
20 ROSMAP Brain Pre-frontal Cortex MED28 0.02 0.01 bslmm 411 0.00 1.9e-01 -4.93 6.8 1.2e-11 -0.30 0.22 0.03 FALSE
21 ROSMAP Brain Pre-frontal Cortex DCAF16 0.04 0.02 bslmm 379 0.01 3.9e-02 -13.58 12.9 6.1e-38 -0.83 0.03 0.89 TRUE
22 YFS Blood DCAF16 0.02 0.02 lasso 1 0.01 1.1e-04 10.49 10.5 1.0e-25 -0.25 0.84 0.04 FALSE
23 The Cancer Genome Atlas Breast Invasive Carcinoma NCAPG 0.03 0.04 enet 5 0.04 8.1e-09 -0.62 -5.5 4.2e-08 0.55 0.95 0.05 TRUE
24 The Cancer Genome Atlas Colon Adenocarcinoma NCAPG 0.08 0.04 blup 34 0.09 1.1e-05 -13.70 -12.1 8.1e-34 0.84 0.01 0.98 FALSE
25 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma FAM184B 0.02 0.03 lasso 2 0.02 2.6e-03 -5.21 -5.3 1.4e-07 0.16 0.24 0.03 FALSE
26 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma NCAPG 0.14 0.07 lasso 3 0.07 5.2e-08 -13.58 -13.3 4.3e-40 0.84 0.71 0.28 FALSE
27 The Cancer Genome Atlas Brain Lower Grade Glioma DCAF16 0.09 0.02 lasso 3 0.04 5.2e-05 10.49 14.9 5.1e-50 -0.64 0.09 0.78 FALSE
28 The Cancer Genome Atlas Brain Lower Grade Glioma NCAPG 0.02 0.03 lasso 1 0.02 9.0e-04 -13.70 -13.7 1.1e-42 0.88 0.03 0.57 FALSE
29 The Cancer Genome Atlas Lung Adenocarcinoma NCAPG 0.06 0.02 blup 34 0.04 1.0e-05 -13.70 -8.8 1.6e-18 0.68 0.04 0.73 TRUE
30 The Cancer Genome Atlas Prostate Adenocarcinoma DCAF16 0.04 0.04 blup 31 0.04 2.2e-05 9.11 13.3 2.2e-40 -0.58 0.28 0.22 FALSE
31 The Cancer Genome Atlas Prostate Adenocarcinoma NCAPG 0.02 0.02 blup 34 0.02 3.4e-03 -12.47 -11.5 2.1e-30 0.76 0.01 0.77 FALSE
32 The Cancer Genome Atlas Stomach Adenocarcinoma LAP3 0.07 0.03 blup 36 0.06 5.3e-05 -3.19 -5.2 2.2e-07 0.15 0.03 0.96 FALSE
33 The Cancer Genome Atlas Thyroid Carcinoma DCAF16 0.07 0.04 blup 31 0.07 4.9e-07 10.26 14.2 4.6e-46 -0.65 0.14 0.79 FALSE