[Hub]/) : Traits : Whole body water mass : ← →

chr4:85,698,680-88,430,396

Best TWAS P=7.15e-11 · Best GWAS P=9.74e-11 conditioned to 0.0324

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PTPN13 0.13 0.18 bslmm 418 0.18 6.8e-22 5.6 -6.0 2.7e-09 -0.44 0.52 0.47 FALSE
2 GTEx Artery Aorta MAPK10 0.15 0.17 enet 16 0.17 1.4e-09 6.2 -6.1 1.1e-09 -0.81 0.01 0.99 FALSE
3 GTEx Artery Aorta ARHGAP24 0.24 0.13 enet 8 0.14 2.2e-08 -4.1 -5.2 1.5e-07 -0.06 0.69 0.31 FALSE
4 GTEx Artery Aorta RP13-514E23.2 0.26 0.09 lasso 6 0.10 2.2e-06 -5.5 -5.5 4.2e-08 -0.05 0.38 0.62 FALSE
5 GTEx Artery Tibial ARHGAP24 0.26 0.19 enet 14 0.21 2.7e-16 -5.5 -5.3 1.1e-07 -0.01 0.30 0.70 FALSE
6 GTEx Artery Tibial RP13-514E23.2 0.22 0.16 enet 10 0.18 1.2e-13 -5.5 -5.6 2.8e-08 -0.04 0.33 0.67 TRUE
7 GTEx Brain Caudate basal ganglia PTPN13 0.26 0.16 enet 17 0.11 4.6e-04 5.7 -5.4 7.6e-08 -0.34 0.24 0.47 FALSE
8 GTEx Colon Sigmoid MAPK10 0.25 0.11 lasso 8 0.07 1.6e-03 6.3 -6.5 7.1e-11 -0.74 0.02 0.96 TRUE
9 GTEx Thyroid PTPN13 0.41 0.31 lasso 6 0.30 3.2e-23 6.5 6.3 2.8e-10 0.81 0.01 0.99 FALSE
10 ROSMAP Brain Pre-frontal Cortex PTPN13 0.09 0.03 blup 409 0.07 4.7e-09 5.6 -6.0 1.8e-09 -0.45 0.50 0.50 FALSE