[Hub]/) : Traits : Whole body water mass :

chr1:40,748,755-42,542,658

Best TWAS P=2.2e-38 · Best GWAS P=1.15e-30 conditioned to 0.00641

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta CTPS1 0.10 0.00 enet 8 0.00 4.6e-01 8.85 9.4 7.4e-21 0.75 0.05 0.60 FALSE
2 GTEx Artery Coronary CTPS1 0.25 -0.01 enet 23 0.00 3.0e-01 0.66 5.9 4.6e-09 0.39 0.07 0.13 FALSE
3 GTEx Brain Cerebellum FOXO6 0.35 0.33 enet 21 0.36 1.2e-11 3.33 5.7 1.6e-08 -0.01 0.99 0.00 FALSE
4 GTEx Breast Mammary Tissue (Female) CTPS1 0.12 -0.01 lasso 4 -0.01 7.5e-01 8.03 7.0 1.7e-12 0.61 0.04 0.10 FALSE
5 GTEx Cells EBV-transformed lymphocytes CTPS1 0.26 0.11 lasso 6 0.08 1.6e-03 9.17 8.8 2.2e-18 0.70 0.19 0.36 FALSE
6 GTEx Colon Transverse SCMH1 0.16 0.07 enet 21 0.06 1.3e-03 0.73 -5.2 1.7e-07 -0.23 0.22 0.09 FALSE
7 GTEx Lung CTPS1 0.06 0.04 lasso 3 0.04 2.4e-04 9.42 9.8 9.1e-23 0.77 0.22 0.63 FALSE
8 GTEx Nerve Tibial SCMH1 0.16 0.03 enet 24 0.07 1.6e-05 11.08 -10.3 8.0e-25 -0.70 0.04 0.96 FALSE
9 GTEx Testis SLFNL1 0.30 0.17 lasso 14 0.28 5.3e-13 11.36 8.2 1.6e-16 0.85 0.01 0.99 FALSE
10 GTEx Testis CTPS1 0.57 0.28 enet 17 0.38 1.0e-17 -3.60 6.0 1.5e-09 0.48 0.97 0.03 FALSE
11 METSIM Adipose CTPS1 0.11 0.09 enet 31 0.09 6.2e-14 -3.60 5.3 1.1e-07 0.28 1.00 0.00 FALSE
12 ROSMAP Brain Pre-frontal Cortex CTPS1 0.04 0.04 enet 7 0.04 9.1e-06 8.01 6.0 2.6e-09 0.59 0.60 0.16 FALSE
13 The Cancer Genome Atlas Breast Invasive Carcinoma SLFNL1 0.03 0.01 enet 6 0.02 5.6e-05 -1.26 6.1 1.1e-09 0.58 0.11 0.74 FALSE
14 The Cancer Genome Atlas Brain Lower Grade Glioma CTPS 0.05 0.04 blup 49 0.03 1.0e-04 -3.60 5.3 9.7e-08 0.33 0.13 0.07 FALSE
15 The Cancer Genome Atlas Brain Lower Grade Glioma SCMH1 0.04 0.01 enet 7 0.02 2.5e-03 0.12 -7.9 3.0e-15 -0.70 0.01 0.82 FALSE
16 The Cancer Genome Atlas Prostate Adenocarcinoma SCMH1 0.03 0.03 lasso 2 0.02 6.2e-03 11.51 -11.5 1.1e-30 -1.00 0.01 0.96 FALSE
17 The Cancer Genome Atlas Testicular Germ Cell Tumors SCMH1 0.35 0.14 blup 96 0.14 1.5e-05 -5.17 6.7 1.6e-11 0.47 0.17 0.26 FALSE
18 The Cancer Genome Atlas Thyroid Carcinoma SCMH1 0.07 0.08 blup 97 0.07 2.5e-07 11.04 -13.0 2.2e-38 -0.75 0.20 0.80 TRUE