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chr17:4,488,884-6,068,117

Best TWAS P=1.46e-09 · Best GWAS P=2.68e-08 conditioned to 0.161

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
7	The Cancer Genome Atlas	Glioblastoma Multiforme	RABEP1	0.23	0.13	blup	79	0.15	3.4e-05	4.9	-6.0	1.5e-09	-0.77	0.05	0.85	TRUE
5	ROSMAP	Brain Pre-frontal Cortex	RPAIN	0.06	0.06	lasso	3	0.06	3.1e-08	5.5	-5.8	7.4e-09	-0.98	0.00	1.00	FALSE
2	GTEx	Esophagus Gastroesophageal Junction	RABEP1	0.19	-0.01	lasso	13	0.00	4.2e-01	4.7	-5.7	1.6e-08	-0.82	0.03	0.80	FALSE
6	The Cancer Genome Atlas	Glioblastoma Multiforme	NUP88	0.12	0.07	enet	12	0.09	1.2e-03	4.7	-5.6	2.0e-08	-0.78	0.02	0.68	FALSE
3	GTEx	Esophagus Muscularis	RABEP1	0.13	0.09	lasso	10	0.10	2.1e-06	5.5	-5.3	8.6e-08	-0.94	0.02	0.98	FALSE
4	GTEx	Heart Atrial Appendage	RABEP1	0.13	0.10	enet	11	0.12	7.2e-06	5.0	-5.2	2.0e-07	-0.85	0.05	0.94	FALSE
1	GTEx	Esophagus Gastroesophageal Junction	DHX33	0.12	0.08	lasso	5	0.07	1.8e-03	5.5	-5.1	2.7e-07	-0.96	0.02	0.96	FALSE
8	The Cancer Genome Atlas	Thyroid Carcinoma	RABEP1	0.04	0.03	enet	5	0.03	1.5e-03	-4.0	-5.1	2.7e-07	-0.67	0.09	0.82	FALSE