[Hub]/) : Traits : Basal metabolic rate :

chr17:4,488,884-6,068,117

Best TWAS P=1.46e-09 · Best GWAS P=2.68e-08 conditioned to 0.161

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Esophagus Gastroesophageal Junction DHX33 0.12 0.08 lasso 5 0.07 1.8e-03 5.5 -5.1 2.7e-07 -0.96 0.02 0.96 FALSE
2 GTEx Esophagus Gastroesophageal Junction RABEP1 0.19 -0.01 lasso 13 0.00 4.2e-01 4.7 -5.7 1.6e-08 -0.82 0.03 0.80 FALSE
3 GTEx Esophagus Muscularis RABEP1 0.13 0.09 lasso 10 0.10 2.1e-06 5.5 -5.3 8.6e-08 -0.94 0.02 0.98 FALSE
4 GTEx Heart Atrial Appendage RABEP1 0.13 0.10 enet 11 0.12 7.2e-06 5.0 -5.2 2.0e-07 -0.85 0.05 0.94 FALSE
5 ROSMAP Brain Pre-frontal Cortex RPAIN 0.06 0.06 lasso 3 0.06 3.1e-08 5.5 -5.8 7.4e-09 -0.98 0.00 1.00 FALSE
6 The Cancer Genome Atlas Glioblastoma Multiforme NUP88 0.12 0.07 enet 12 0.09 1.2e-03 4.7 -5.6 2.0e-08 -0.78 0.02 0.68 FALSE
7 The Cancer Genome Atlas Glioblastoma Multiforme RABEP1 0.23 0.13 blup 79 0.15 3.4e-05 4.9 -6.0 1.5e-09 -0.77 0.05 0.85 TRUE
8 The Cancer Genome Atlas Thyroid Carcinoma RABEP1 0.04 0.03 enet 5 0.03 1.5e-03 -4.0 -5.1 2.7e-07 -0.67 0.09 0.82 FALSE