[Hub]/) : Traits : Basal metabolic rate : ← →

chr2:85,083,503-86,518,249

Best TWAS P=5.32e-13 · Best GWAS P=1.71e-11 conditioned to 0.0292

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
34	The Cancer Genome Atlas	Prostate Adenocarcinoma	GGCX	0.04	0.02	blup	44	0.02	2.7e-03	5.9	7.2	5.3e-13	0.72	0.10	0.73	TRUE
23	GTEx	Skin Sun Exposed Lower leg	GGCX	0.15	0.11	lasso	3	0.18	7.9e-15	5.5	6.8	1.2e-11	0.69	0.51	0.49	FALSE
21	GTEx	Pancreas	VAMP5	0.29	0.09	enet	4	0.05	3.2e-03	6.0	-6.7	2.0e-11	-0.66	0.02	0.76	FALSE
22	GTEx	Skin Not Sun Exposed Suprapubic	GGCX	0.13	0.04	enet	11	0.06	3.9e-04	5.5	6.6	3.4e-11	0.64	0.27	0.33	FALSE
5	GTEx	Artery Tibial	GGCX	0.29	0.22	enet	14	0.24	6.3e-19	5.5	6.6	4.5e-11	0.69	0.74	0.26	FALSE
20	GTEx	Nerve Tibial	GGCX	0.38	0.30	lasso	7	0.33	6.5e-24	5.5	6.5	8.0e-11	0.72	0.77	0.23	FALSE
25	GTEx	Thyroid	GGCX	0.30	0.17	enet	10	0.23	1.4e-17	5.5	6.5	9.6e-11	0.74	0.73	0.27	FALSE
19	GTEx	Muscle Skeletal	GGCX	0.10	0.04	enet	11	0.02	2.7e-03	5.5	6.5	9.9e-11	0.78	0.09	0.91	FALSE
24	GTEx	Testis	GGCX	0.38	0.36	enet	25	0.40	8.6e-19	5.5	6.4	1.9e-10	0.72	0.70	0.30	FALSE
17	GTEx	Esophagus Muscularis	GGCX	0.14	0.12	lasso	9	0.12	1.1e-07	5.5	6.3	3.2e-10	0.75	0.47	0.53	FALSE
7	GTEx	Brain Cerebellum	GGCX	0.54	0.30	lasso	10	0.34	6.0e-11	5.5	6.2	4.8e-10	0.75	0.76	0.24	FALSE
4	GTEx	Artery Aorta	GGCX	0.23	0.22	lasso	6	0.23	5.5e-13	5.5	6.2	5.6e-10	0.74	0.62	0.38	FALSE
28	YFS	Blood	VAMP8	0.15	0.15	enet	37	0.18	2.2e-55	5.8	-6.0	1.5e-09	-0.75	0.63	0.37	FALSE
13	GTEx	Colon Transverse	GGCX	0.26	0.28	lasso	3	0.28	1.4e-13	5.5	6.0	1.7e-09	0.73	0.69	0.31	FALSE
33	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	VAMP8	0.06	0.01	enet	15	0.02	2.1e-02	6.0	6.0	2.2e-09	0.45	0.04	0.26	FALSE
26	GTEx	Whole Blood	GGCX	0.15	0.14	lasso	4	0.15	1.7e-13	5.5	5.9	3.1e-09	0.73	0.75	0.25	FALSE
14	GTEx	Esophagus Gastroesophageal Junction	GGCX	0.24	0.16	lasso	6	0.12	4.3e-05	5.5	5.9	3.6e-09	0.74	0.32	0.48	FALSE
35	The Cancer Genome Atlas	Soft Tissue Sarcoma	GGCX	0.04	0.03	lasso	2	0.03	1.1e-02	5.8	5.8	9.0e-09	0.70	0.06	0.08	FALSE
16	GTEx	Esophagus Mucosa	TMEM150A	0.10	0.05	enet	5	0.05	3.2e-04	5.5	-5.7	1.1e-08	-0.80	0.07	0.88	FALSE
36	The Cancer Genome Atlas	Thyroid Carcinoma	GGCX	0.03	0.03	enet	5	0.02	8.7e-03	5.3	5.7	1.2e-08	0.82	0.05	0.54	FALSE
6	GTEx	Brain Cerebellar Hemisphere	GGCX	0.46	0.41	enet	16	0.48	5.3e-14	4.8	5.7	1.6e-08	0.72	0.78	0.22	FALSE
15	GTEx	Esophagus Mucosa	GGCX	0.29	0.21	enet	30	0.27	5.8e-18	5.8	5.7	1.6e-08	0.62	0.60	0.40	FALSE
12	GTEx	Cells EBV-transformed lymphocytes	GGCX	0.36	0.31	enet	18	0.29	4.5e-10	4.5	5.6	2.1e-08	0.71	0.74	0.26	FALSE
1	CommonMind	Brain Pre-frontal Cortex	RNF181	0.07	0.02	bslmm	476	0.03	3.4e-04	5.5	5.6	2.6e-08	0.59	0.02	0.91	FALSE
18	GTEx	Lung	GGCX	0.17	0.17	lasso	2	0.18	2.3e-13	5.5	5.5	3.4e-08	0.72	0.78	0.22	FALSE
30	The Cancer Genome Atlas	Brain Lower Grade Glioma	GGCX	0.05	0.05	lasso	1	0.04	1.2e-05	5.5	5.5	3.8e-08	0.72	0.57	0.31	FALSE
37	The Cancer Genome Atlas	Thyroid Carcinoma	VAMP8	0.04	0.05	lasso	3	0.05	1.2e-05	5.5	-5.5	3.8e-08	-0.77	0.32	0.54	FALSE
29	The Cancer Genome Atlas	Colon Adenocarcinoma	C2orf68	0.06	0.06	lasso	2	0.05	1.1e-03	5.5	-5.5	4.2e-08	-0.88	0.02	0.67	FALSE
8	GTEx	Brain Cortex	GGCX	0.38	0.17	enet	30	0.02	1.1e-01	4.8	5.4	5.5e-08	0.60	0.42	0.27	FALSE
10	GTEx	Breast Mammary Tissue	GGCX	0.14	0.01	lasso	3	0.01	1.0e-01	5.5	5.4	6.3e-08	0.69	0.13	0.13	FALSE
11	GTEx	Breast Mammary Tissue (Male)	GGCX	0.10	0.00	enet	4	0.00	3.3e-01	4.2	5.4	6.9e-08	0.69	0.05	0.10	FALSE
2	GTEx	Adipose Subcutaneous	GGCX	0.16	0.09	lasso	5	0.08	3.1e-07	5.5	5.3	9.2e-08	0.71	0.76	0.24	FALSE
31	The Cancer Genome Atlas	Lung Adenocarcinoma	USP39	0.04	0.02	blup	67	0.03	2.0e-04	5.5	-5.3	9.4e-08	-0.76	0.08	0.82	FALSE
3	GTEx	Adipose Visceral Omentum	GGCX	0.13	0.03	lasso	7	0.03	1.1e-02	5.5	5.3	1.1e-07	0.68	0.28	0.35	FALSE
32	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	VAMP5	0.07	0.04	blup	44	0.05	2.1e-06	6.1	-5.3	1.3e-07	-0.49	0.12	0.79	FALSE
27	NTR	Blood	VAMP8	0.05	0.04	lasso	8	0.04	2.0e-12	5.1	-5.2	1.6e-07	-0.74	0.76	0.24	FALSE
9	GTEx	Brain Nucleus accumbens basal ganglia	GGCX	0.28	0.09	enet	7	0.02	7.6e-02	4.8	5.1	2.8e-07	0.67	0.10	0.26	FALSE