TWAS
hub
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Usage
Models
Genes
Traits
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Traits
:
Basal metabolic rate
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chr5:53,702,093-55,248,943
Best TWAS P=3.37e-08 · Best GWAS P=2.68e-08 conditioned to 0.138
53.8M
54M
54.2M
54.4M
54.6M
54.8M
55M
55.2M
0
2
4
6
8
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
The Cancer Genome Atlas
Thyroid Carcinoma
SLC38A9
0.03
0.04
blup
52
0.04
2.0e-04
5.3
5.5
3.4e-08
0.88
0.03
0.96
TRUE
1
GTEx
Brain Hippocampus
GZMA
0.32
0.00
lasso
6
0.02
1.3e-01
3.8
5.5
4.5e-08
0.42
0.04
0.52
FALSE
3
The Cancer Genome Atlas
Breast Invasive Carcinoma
PPAP2A
0.06
0.03
lasso
1
0.03
1.1e-06
5.5
-5.5
5.0e-08
-0.88
0.00
1.00
FALSE
2
GTEx
Breast Mammary Tissue (Female)
GPX8
0.04
0.00
lasso
2
0.03
5.0e-02
5.4
-5.2
1.7e-07
-0.85
0.05
0.22
FALSE