Best TWAS P=3.37e-08 · Best GWAS P=2.68e-08 conditioned to 0.138
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Hippocampus | GZMA | 0.32 | 0.00 | lasso | 6 | 0.02 | 1.3e-01 | 3.8 | 5.5 | 4.5e-08 | 0.42 | 0.04 | 0.52 | FALSE |
| 2 | GTEx | Breast Mammary Tissue (Female) | GPX8 | 0.04 | 0.00 | lasso | 2 | 0.03 | 5.0e-02 | 5.4 | -5.2 | 1.7e-07 | -0.85 | 0.05 | 0.22 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | PPAP2A | 0.06 | 0.03 | lasso | 1 | 0.03 | 1.1e-06 | 5.5 | -5.5 | 5.0e-08 | -0.88 | 0.00 | 1.00 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | SLC38A9 | 0.03 | 0.04 | blup | 52 | 0.04 | 2.0e-04 | 5.3 | 5.5 | 3.4e-08 | 0.88 | 0.03 | 0.96 | TRUE |