TWAS hub - GZMA

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Hippocampus	0.3206	0.1055	0.00430	0.001	NA	-0.001	NA	0.017	0.290	NA	0.34000	NA	0.130
2	GTEx	Testis	0.1040	0.0470	0.00260	0.040	NA	0.022	NA	0.033	0.007	NA	0.03500	NA	0.014
3	YFS	Blood	0.0288	0.0112	0.00081	0.003	0.003	0.010	0.007	0.007	0.036	0.023	0.00022	0.0019	0.002

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Sitting height	4.3	30.4	57.0	7.5	5.2	-2.6
Trunk fat-free mass	4.1	23.7	42.8	6.5	5.0	-2.0
Trunk predicted mass	4.1	23.6	42.4	6.5	5.0	-1.9
Standing height	4.1	40.5	80.8	9.0	5.9	-2.5
Age at First Birth	4.0	5.8	12.2	3.5	1.7	-1.5
Handedness (chirality/laterality): Left-handed	4.0	4.8	13.1	3.6	0.5	-1.0
Arm predicted mass (right)	3.9	19.8	33.1	5.8	4.6	-2.3
Arm fat-free mass (right)	3.8	19.6	32.1	5.7	4.7	-2.2
Whole body fat-free mass	3.7	21.3	36.8	6.1	4.8	-2.1
Height	3.6	69.1	157.3	12.5	6.5	-2.9
Whole body water mass	3.6	20.6	36.1	6.0	4.7	-2.0
Comparative height size at age 10	3.5	19.5	40.2	6.3	4.1	-1.2
Arm fat-free mass (left)	3.4	17.2	28.4	5.3	4.3	-2.1
Arm predicted mass (left)	3.2	16.2	28.3	5.3	4.0	-2.0
Lung FEV1/FVC ratio	3.0	15.3	24.4	-4.9	-4.6	-0.6
Basal metabolic rate	3.0	16.9	29.9	5.5	4.2	-1.8
Leg fat-free mass (left)	2.9	15.1	25.6	5.1	4.1	-1.8
Leg predicted mass (left)	2.8	15.1	25.5	5.0	4.1	-1.8
Leg fat-free mass (right)	2.8	15.2	25.3	5.0	4.1	-1.9
Leg predicted mass (right)	2.8	15.0	25.3	5.0	4.0	-1.9
Ovarian Cancer	2.7	3.6	4.1	-2.0	-1.8	1.9
Had menopause	2.5	3.1	6.4	2.5	1.6	0.5
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.3	2.7	4.3	-1.9	-2.1	0.1
Bipolar Disorder (2011)	2.2	2.1	6.1	0.1	0.6	2.5
Lung FVC	2.1	10.9	18.9	-3.7	-4.3	-0.7
Diabetes (mother)	2.1	2.6	7.8	0.3	-0.1	-2.8
Type 2 Diabetes (T2D) (2012)	2.0	2.3	4.3	1.6	0.3	-2.1
Pulse wave Arterial Stiffness index	2.0	2.3	4.3	0.5	1.6	2.1
Number of children fathered	2.0	2.2	3.2	-1.4	-1.8	1.2
Pulse wave peak to peak time	2.0	2.3	5.5	0.0	-1.2	-2.3
Emphysema/chronic bronchitis	2.0	2.3	5.0	0.8	2.2	-1.1
Heart disease (mother)	2.0	2.4	4.0	1.8	2.0	-0.3
Heel T-Score	1.9	14.8	41.2	-0.3	-6.4	-1.8
Respiratory disease	1.9	4.2	7.6	2.8	2.2	-0.5
Hearing difficulty/problems: Yes	1.9	3.0	6.0	-0.9	-1.4	2.5
Diastolic blood pressure, automated reading	1.9	5.9	9.7	2.5	3.1	-1.3
Mean Putamen Volume	1.8	2.1	3.9	1.5	2.0	0.1
Medication: Atenolol	1.8	2.2	6.6	0.2	0.3	2.6
Falls in the last year	1.8	2.5	3.4	1.4	1.4	1.9
Illnesses of father: Heart disease	1.8	2.5	4.1	2.0	1.8	-0.6
Qualifications: None of the above	1.7	3.5	5.1	-1.4	-2.3	1.9
Medication: Ibuprofen (e.g. Nurofen)	1.7	2.2	4.1	1.6	2.0	0.1
Number of full brothers	1.7	2.1	3.6	-1.3	-1.9	1.0
Alzheimer’s Disease (in mother)	1.6	1.8	3.4	1.8	1.3	0.6
Qualifications: CSEs or equivalent	1.6	2.1	5.0	-2.2	-1.0	-0.6
Hearing difficulty/problems with background noise	1.6	2.6	3.2	-1.3	-1.8	1.8
Family relationship satisfaction	1.6	1.9	3.2	1.8	1.1	-1.2
Waist Hip Ratio (WHR)	1.5	6.8	10.3	3.2	3.1	0.6
Frequency of tenseness / restlessness in last 2 weeks	1.5	2.4	3.8	1.8	1.9	-0.4
Smoking status: Previous	1.5	2.2	4.6	-0.9	-2.1	1.1
Mouth/teeth dental problems: Mouth ulcers	1.5	2.4	6.3	-0.6	-0.8	2.5
Alzheimer’s Disease (including proxy)	1.4	2.1	4.1	1.5	2.0	-0.0
Number of treatments/medications taken	1.4	2.5	4.5	2.1	1.3	1.2
Heel bone mineral density (BMD) T-score, automated (right)	1.4	3.3	9.0	0.9	-3.0	-0.1
Mouth/teeth dental problems	1.4	2.1	5.3	0.3	1.0	-2.3
Weight	1.4	7.1	12.8	3.6	2.8	-0.6
Frequency of tiredness / lethargy in last 2 weeks	1.4	2.3	2.8	1.6	1.7	-1.2
Prospective memory result	1.4	1.7	3.4	-0.9	-1.0	1.8
Pulse wave reflection index	1.4	1.8	3.3	0.4	1.8	1.4
Illnesses of siblings: Diabetes	1.4	1.7	4.5	0.7	0.4	-2.1
Long-standing illness, disability or infirmity	1.4	2.2	6.0	0.3	0.6	2.4
Diabetes diagnosed by doctor	1.4	2.3	5.4	1.2	0.1	2.3
Body Mass Index (BMI) (2010)	1.3	1.8	5.2	0.5	2.3	0.1
Fasting Glucose	1.3	1.5	3.0	-1.2	-1.7	0.3
Supplements: Zinc	1.3	1.4	2.0	0.9	1.1	1.4
Diabetes (self-reported)	1.3	1.9	5.2	0.8	-0.2	2.3
Mouth/teeth dental problems: Dentures	1.3	2.3	5.7	-0.8	-0.7	2.4
Seen doctor (GP) for nerves, anxiety, tension or depression	1.3	2.0	3.8	1.2	0.9	-2.0
Mouth/teeth dental problems: Bleeding gums	1.3	1.7	2.6	1.6	0.2	-1.6
Headache pain in last month	1.3	2.2	5.1	2.3	1.2	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.3	2.8	5.7	-1.6	-2.4	0.5
Average weekly beer plus cider intake	1.3	1.9	3.3	1.8	1.5	-0.2
Major Depression (MDD)	1.2	1.4	3.1	1.0	1.8	-0.4
Schizophrenia (2014)	1.2	2.5	6.9	0.7	-0.5	2.6
Blood Eosinophil Count	1.2	9.1	25.5	-1.2	-5.0	0.6
Type 2 Diabetes (T2D) (2018)	1.2	2.3	5.7	1.0	0.6	2.4
Illnesses of siblings	1.2	1.6	3.6	-1.1	0.2	1.9
Wheeze or whistling in the chest in last year	1.2	2.1	4.4	2.1	1.2	-0.6
Reason for reducing amount of alcohol drunk: Health precaution	1.2	1.4	2.7	0.8	1.7	1.0
Angina (self-reported)	1.2	1.6	2.3	-1.3	-0.9	1.5
Chest pain or discomfort	1.2	1.8	2.5	1.4	1.6	0.9
Smoking status: Current	1.2	1.9	4.1	2.0	1.2	-0.5
Supplements: Fish oil (including cod liver oil)	1.2	1.5	1.8	1.2	1.3	1.1
Medication: Lisinopril	1.2	1.6	3.4	-1.8	-1.2	-0.2
Primary Biliary Cirrhosis	1.1	1.5	3.1	-0.0	-1.2	1.8
Relative age of first facial hair	1.1	2.2	5.4	2.3	0.9	0.7
Medication: Metformin	1.1	1.5	3.8	0.5	-0.8	2.0
Frequency of unenthusiasm / disinterest in last 2 weeks	1.1	1.4	4.1	2.0	0.4	-0.3
Heel bone mineral density (BMD) T-score, automated (left)	1.1	2.4	5.3	1.3	-2.3	-0.5
Time employed in main current job	1.1	1.3	1.6	-0.9	-1.3	1.1
Pain type(s) experienced in last month: Hip pain	1.1	1.3	3.6	0.6	1.9	0.3
Basal cell carcinoma (self-reported)	1.1	1.3	4.0	-0.1	-0.1	2.0
Irritable Bowel Disease (IBD)	1.0	2.3	6.7	0.5	0.3	2.6
Chronotype (morning person)	1.0	2.3	6.1	-0.7	-0.7	2.5
Angina	1.0	1.3	2.2	-1.1	-0.8	1.5
Tinnitus: Yes, but not now, but have in the past	1.0	1.1	1.2	-0.9	-1.1	1.1
Past tobacco smoking	1.0	1.8	4.5	0.0	2.1	-0.9
Lung cancer (father)	1.0	1.2	2.3	1.5	1.0	-0.5
Loud music exposure frequency	1.0	1.1	2.4	0.4	1.6	-0.8
Glaucoma (self-reported)	1.0	1.2	3.3	0.4	-0.3	1.8
Ever taken oral contraceptive pill	1.0	1.1	1.9	0.9	-1.4	-0.7
Ulcerative Colitis	0.9	1.4	3.9	0.2	-0.4	2.0
Forced vital capacity (FVC)	0.9	3.6	5.6	2.2	0.8	-2.4
Pain all over the body in last month	0.9	1.0	2.0	-0.2	-0.9	1.4
Hair/balding pattern: Pattern 3	0.9	1.3	2.6	-1.0	-0.6	1.6
Peak expiratory flow (PEF)	0.9	2.1	3.9	-1.5	-0.2	-2.0
Medication for cholesterol, blood pressure or diabetes	0.9	1.4	2.2	-1.4	0.3	-1.5
Hypothyroidism/myxoedema (self-reported)	0.9	1.7	3.7	0.2	1.1	1.9
Medication: Blood pressure	0.9	1.7	2.5	0.1	-1.6	1.6
Migraine (self-reported)	0.9	1.1	1.8	1.4	0.9	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.9	1.0	2.0	1.4	0.9	-0.6
Guilty feelings	0.9	1.3	1.7	1.3	1.0	1.2
Wears glasses or contact lenses	0.9	1.0	1.4	1.2	1.1	0.7
Tinnitus: Yes, now most or all of the time	0.9	1.1	1.8	0.7	1.0	1.3
HDL Cholesterol	0.8	1.4	3.2	1.0	0.4	1.8
Neuroticism (2016)	0.8	1.2	1.9	1.3	1.4	-0.1
Current tobacco smoking	0.8	1.4	2.4	1.5	1.2	-0.6
Bilateral oophorectomy (both ovaries removed)	0.8	0.9	2.8	-0.2	1.7	-0.0
Multivitamins +/- minerals	0.8	1.0	3.0	0.1	1.7	0.2
Hair/balding pattern: Pattern 2	0.8	1.1	2.6	0.2	0.8	-1.6
Financial difficulties in last 2 years	0.8	1.1	1.5	-1.2	-0.6	1.2
Fluid intelligence score	0.8	1.6	2.9	1.7	0.7	-1.2
Forced expiratory volume in 1-second (FEV1)	0.8	2.6	6.7	-0.1	-1.1	-2.6
Noisy workplace	0.8	1.0	2.1	-1.5	-0.8	0.6
Medication: Lansoprazole	0.8	0.9	2.2	0.7	1.5	-0.2
Breastfed as a baby	0.8	1.0	2.6	-1.6	-0.4	0.5
Forced vital capacity (FVC), Best measure	0.8	2.9	4.1	2.0	0.7	-2.0
Qualifications: NVQ or HND or HNC or equivalent	0.8	1.0	2.2	-1.5	-0.8	0.4
Ever had stillbirth, spontaneous miscarriage or termination	0.8	0.9	2.1	-0.2	-0.7	-1.4
High cholesterol (Self-reported)	0.8	1.5	2.4	1.6	1.3	-0.6
Medication: Bendroflumethiazide	0.8	1.3	3.3	0.4	0.6	1.8
Ever had prostate specific antigen (PSA) test	0.8	1.0	1.6	-0.7	-1.3	-1.0
Pain experienced in last month	0.8	1.4	3.6	0.3	0.6	-1.9
Pack years of smoking	0.8	1.2	2.2	0.1	1.5	1.1
Bipolar Disorder or Schizophrenia	0.7	1.7	4.8	0.4	-0.1	2.2
Schizophrenia (2018)	0.7	1.5	2.8	1.3	-0.1	1.7
Ulcerative Colitis (UC)	0.7	1.4	3.8	0.4	0.4	1.9
Pack years adult smoking proportion	0.7	1.1	2.8	0.1	1.7	0.7
Townsend deprivation index at recruitment	0.7	0.9	2.6	0.1	0.5	1.6
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	2.0	-1.4	-0.7	0.5
Number of live births	0.7	1.0	1.4	-1.1	-0.5	-1.2
Happiness	0.7	0.8	1.3	0.7	0.8	-1.2
Qualifications: A levels/AS levels or equivalent	0.7	1.5	3.5	0.1	0.9	-1.9
Length of working week for main job	0.7	0.8	1.9	-1.4	0.8	0.0
Medication: Ventolin 100micrograms inhaler	0.7	0.8	1.5	0.0	1.2	1.0
Age at last live birth	0.7	1.1	1.6	-0.5	-1.3	-1.2
Bipolar Disorder (2018)	0.6	1.0	2.0	-1.0	-0.0	1.4
Alzheimer’s Disease (in father)	0.6	0.7	2.0	0.0	1.4	-0.1
Crohns Disease (2012)	0.6	0.9	2.6	-0.2	-0.1	1.6
HbA1C	0.6	0.7	0.9	0.8	0.7	-0.9
Rheumatoid Arthritis	0.6	0.8	1.8	-0.7	-0.3	1.3
Hypothyroidism (self reported)	0.6	1.4	4.1	-0.1	0.4	2.0
Hand grip strength (left)	0.6	1.5	3.3	1.1	0.2	-1.8
Average weekly spirits intake	0.6	0.8	1.8	0.6	0.5	1.3
Ever used hormone-replacement therapy (HRT)	0.6	0.8	1.2	0.9	1.1	-0.6
Medication: Co-codamol	0.6	0.6	1.2	1.1	0.1	-0.9
Taking other prescription medications	0.6	0.8	1.5	1.2	0.4	0.9
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	1.4	-0.7	1.2	-0.4
High blood pressure (mother)	0.6	0.8	1.2	-1.1	-0.6	-1.0
Waist circumference	0.6	2.1	3.0	1.7	1.7	0.7
Medication: Cholesterol lowering	0.6	0.9	1.5	1.2	-0.0	1.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.8	4.6	0.7	-0.4	-2.1
Medication: Paracetamol	0.6	0.9	2.2	0.5	0.6	1.5
Chronic bronchitis/emphysema (mother)	0.6	0.7	1.0	1.0	0.8	0.7
Age at first live birth	0.6	1.0	1.5	1.2	-0.5	-1.1
Qualifications: College or University degree	0.6	1.9	3.5	0.7	1.3	-1.9
Mouth/teeth dental problems: Loose teeth	0.6	0.7	1.1	1.0	-1.1	-0.0
Medication: Ibuprofen	0.6	0.7	1.1	0.7	1.1	0.7
Pulse rate, automated reading	0.6	2.0	3.7	0.5	1.4	-1.9
Leg pain on walking	0.6	0.7	1.0	1.0	0.9	-0.6
Average weekly red wine intake	0.6	0.9	2.0	1.4	-0.2	-0.8
Eye problems/disorders: Cataract	0.6	0.7	1.3	0.7	-0.5	1.1
Breast cancer (self-reported)	0.6	0.7	1.1	-0.5	0.7	-1.1
Illnesses of father: None of the above (group 1)	0.6	0.7	1.8	-1.4	0.1	-0.5
Number of self-reported non-cancer illnesses	0.6	1.0	2.7	0.0	-0.5	1.7
Eye problems/disorders: Glaucoma	0.6	0.8	1.4	-0.9	-1.2	0.2
Heart disease (siblings)	0.6	0.7	1.4	0.8	-0.3	1.2
Crohns Disease (2017)	0.5	1.1	1.8	1.0	0.6	1.4
Blood Platelet Count	0.5	5.5	13.2	3.6	1.8	-0.5
Blood White Count	0.5	3.5	5.7	2.4	2.1	-0.5
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	1.8	0.2	0.5	1.4
Impedance of leg (right)	0.5	2.4	3.7	-1.8	-1.9	0.4
Age when periods started (menarche)	0.5	1.2	3.0	1.7	0.8	-0.2
Impedance of leg (left)	0.5	2.5	3.9	-2.0	-1.8	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	1.3	0.8	-0.0	1.1
Illnesses of mother	0.5	0.6	1.0	-0.9	-1.0	-0.1
High blood pressure (siblings)	0.5	0.8	2.1	0.4	0.1	-1.4
Medication for pain relief, constipation, heartburn	0.5	0.8	0.8	-0.8	-0.9	-0.9
Number of full sisters	0.5	0.6	0.9	-0.7	-0.6	-1.0
Suffer from ‘nerves’	0.5	0.8	1.7	-0.2	0.8	1.3
Loneliness, isolation	0.5	0.7	1.5	-1.2	-0.7	0.3
Average weekly champagne plus white wine intake	0.5	0.7	1.1	-0.4	-1.1	0.9
Medication: Paracetamol	0.5	0.8	1.9	0.5	0.5	1.4
Alcohol drinker status: Never	0.5	0.6	0.9	-0.9	-0.3	-1.0
Myopia	0.5	0.7	1.5	0.5	0.6	1.2
Impedance of whole body	0.5	2.6	3.8	-1.9	-1.9	0.4
Neuroticism	0.4	0.9	2.4	0.5	1.6	0.2
Medication for hormone replacement therapy	0.4	0.5	0.8	-0.9	0.5	0.6
Vitamin and mineral supplements	0.4	0.6	1.1	-0.1	-1.1	-0.8
Average weekly fortified wine intake	0.4	0.5	1.2	0.3	1.1	-0.3
Maternal smoking around birth	0.4	0.6	1.2	1.1	-0.0	-0.8
Relative age voice broke	0.4	0.6	1.3	1.1	-0.4	-0.6
Hayfever, allergic rhinitis or eczema	0.4	0.8	2.0	-0.5	-1.4	0.2
Medication: Levothyroxine sodium	0.4	0.7	1.5	0.3	1.2	0.7
Trunk fat mass	0.4	1.7	3.0	1.7	1.4	0.1
Ever unenthusiastic/disinterested for a whole week	0.4	0.5	0.9	0.6	1.0	-0.4
Impedance of arm (right)	0.4	2.0	2.8	-1.4	-1.7	1.0
Ever highly irritable/argumentative for 2 days	0.4	0.4	1.1	-0.2	0.5	-1.0
Blood clot in the leg (DVT)	0.4	0.5	1.2	1.1	-0.4	0.3
Comparative body size at age 10	0.4	1.0	2.9	0.0	0.2	-1.7
Health satisfaction	0.4	0.6	0.9	0.7	0.6	0.9
Medication: Allopurinol	0.4	0.5	0.8	-0.9	-0.1	0.8
Overall health rating	0.4	0.9	1.1	1.0	1.0	0.8
Had major operations	0.4	0.5	1.2	0.3	0.4	1.1
Commuting to job workplace: Car/motor vehicle	0.4	0.5	1.0	-0.6	-1.0	0.1
Medication: Aspirin	0.4	0.6	0.9	0.9	0.9	0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.9	1.4	1.2	0.2	-1.1
Mineral and other dietary supplements	0.4	0.5	1.1	-0.3	-0.6	-1.1
Medication: Aspirin	0.4	0.5	0.6	0.7	0.6	0.8
Medication: Gliclazide	0.4	0.5	1.1	-0.2	-0.5	1.1
Illnesses of father: High blood pressure	0.4	0.5	1.2	-0.1	-1.1	0.5
Fractured/broken bones in last 5 years	0.4	0.5	1.0	-1.0	-0.3	0.6
Age started oral contraceptive pill	0.4	0.5	1.3	0.0	1.1	0.3
Cholesterol lowering medication	0.4	0.6	1.7	0.2	1.3	0.2
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	1.5	1.2	-0.4	0.0
Neuroticism (Nagel 2018)	0.3	0.8	2.0	-0.0	0.5	-1.4
Worry (Nagel 2018)	0.3	0.7	1.3	0.2	1.1	-0.8
Reaction Time	0.3	0.6	1.5	-0.5	-0.3	-1.2
LDL Cholesterol	0.3	0.4	0.8	-0.4	0.9	0.5
Triglycerides	0.3	0.5	1.4	0.4	1.2	-0.2
Blood Red Count	0.3	2.7	3.1	1.8	1.6	-1.6
Smoking Status	0.3	0.8	1.1	0.9	-1.1	-0.6
Systolic blood pressure, automated reading	0.3	0.7	1.6	0.6	1.3	0.5
Diabetes (father)	0.3	0.3	0.5	0.7	0.7	0.2
Severe depression (siblings)	0.3	0.4	0.7	0.8	0.5	0.4
Medication: Ramipril	0.3	0.4	0.7	0.6	0.2	0.8
Medication: Simvastatin	0.3	0.5	0.5	0.7	0.7	0.7
Arm fat percentage (right)	0.3	1.0	2.3	-0.7	-0.4	1.5
Depression (self-reported)	0.3	0.3	0.6	0.2	-0.7	0.6
Impedance of arm (left)	0.3	1.2	2.0	-1.2	-1.4	0.5
Tense / ‘highly strung’	0.3	0.5	0.6	-0.6	-0.6	0.8
Birth weight of first child	0.3	0.6	1.4	1.2	0.3	-0.6
Medication: Amlodipine	0.3	0.4	0.9	1.0	0.1	0.4
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.2	1.1	0.2	0.1
Medication: Omeprazole	0.3	0.4	0.9	-0.2	-0.3	1.0
Medication: Seretide 50 evohaler	0.3	0.3	0.5	0.6	-0.1	0.7
Whole body fat mass	0.3	1.1	1.6	1.3	1.3	0.4
Leg fat mass (right)	0.3	1.2	2.0	1.3	1.4	0.0
Supplements: Vitamin C	0.3	0.4	0.6	0.3	0.7	0.8
Knee pain experienced in last month	0.3	0.5	1.2	-0.6	-0.0	1.1
Arm fat mass (left)	0.3	1.3	2.0	1.4	1.4	0.2
Hearing aid user	0.3	0.4	0.9	-0.4	-0.9	-0.0
Irritability	0.3	0.6	0.8	0.9	0.9	-0.5
Risk taking	0.3	0.5	0.9	-0.1	0.7	-1.0
Unable to work because of sickness or disability	0.3	0.4	0.8	0.0	-0.6	0.9
Leg fat mass (left)	0.3	1.2	2.2	1.2	1.5	0.3
Depressed Affect (Nagel 2018)	0.2	0.5	1.3	-0.5	0.2	-1.1
Depression (Nagel 2018)	0.2	0.3	0.7	0.9	-0.5	-0.2
Intelligence (Savage-Jansen 2018)	0.2	0.7	1.2	0.8	1.1	-0.6
Schizophrenia vs Biploar Disorder	0.2	0.3	0.7	-0.1	-0.8	-0.5
Verbal and Numeric Reasoning (VNR)	0.2	0.5	0.9	0.4	0.6	-1.0
Breast Cancer	0.2	0.4	0.5	-0.7	-0.7	0.5
Prostate Cancer	0.2	0.3	0.6	-0.1	0.6	-0.8
Systolic Blood Pressure	0.2	0.9	1.5	1.2	0.6	0.9
Cardiovascular Disease	0.2	0.8	1.6	1.2	0.8	-0.0
Hand grip strength (right)	0.2	0.5	0.6	0.7	-0.6	-0.8
Stomach or abdominal pain in last month	0.2	0.3	0.3	0.5	0.5	-0.5
Alcohol usually taken with meals	0.2	0.3	1.0	-0.1	0.2	1.0
Nervous feelings	0.2	0.4	0.5	-0.6	0.7	-0.6
Had other major operations	0.2	0.3	0.4	-0.5	0.3	0.7
Heart attack	0.2	0.3	0.4	-0.6	-0.6	0.1
Hip circumference	0.2	1.0	1.4	1.2	1.1	-0.6
Worrier / anxious feelings	0.2	0.4	0.8	0.1	0.7	-0.9
Asthma	0.2	0.3	0.5	0.7	0.4	-0.5
Arm fat mass (right)	0.2	0.8	1.2	1.1	1.1	0.4
Exposure to tobacco smoke outside home	0.2	0.2	0.4	0.2	0.4	0.6
Worry too long after embarrassment	0.2	0.4	1.0	0.3	0.0	-1.0
Eye problems/disorders: None of the above	0.2	0.2	0.4	-0.2	0.6	-0.5
Neck or shoulder pain in last month	0.2	0.3	0.4	0.6	0.5	-0.6
Alcohol intake frequency.	0.2	0.5	0.9	-0.8	1.0	0.0
Mood swings	0.2	0.4	0.8	0.9	0.1	-0.7
Asthma (self-reported)	0.2	0.5	1.0	1.0	0.4	-0.5
Miserableness	0.2	0.3	0.5	-0.4	-0.7	-0.6
Mother’s age at death	0.2	0.2	0.6	0.1	0.8	-0.1
Financial situation satisfaction	0.2	0.3	0.8	-0.2	0.2	-0.9
Ever smoked	0.2	0.3	0.6	0.5	-0.8	-0.1
Leg fat percentage (left)	0.2	0.6	1.2	-0.8	0.1	1.1
Number of operations (self-reported)	0.2	0.4	0.5	0.4	0.6	0.7
Medication: Omeprazole (e.g. Zanprol)	0.2	0.2	0.5	0.1	0.7	0.1
Supplements: Calcium	0.2	0.3	0.7	0.3	0.2	-0.8
Coronary Artery Disease (CAD)	0.1	0.1	0.2	0.5	0.2	0.1
Lupus	0.1	0.2	0.6	0.1	-0.0	-0.8
BMI	0.1	0.6	1.4	-0.4	0.5	1.2
Allergy or Eczema	0.1	0.2	0.5	0.3	-0.7	-0.2
Tanning	0.1	0.7	1.3	-0.9	-1.1	0.4
Sensitivity / hurt feelings	0.1	0.2	0.5	-0.7	-0.4	0.1
Ever had hysterectomy (womb removed)	0.1	0.1	0.1	-0.4	0.3	0.4
Eye problems/disorders: Diabetes related eye disease	0.1	0.1	0.2	0.2	0.1	-0.4
Trunk fat percentage	0.1	0.3	0.7	-0.1	0.1	0.9
Fed-up feelings	0.1	0.2	0.4	-0.1	0.6	-0.5
Serious illness, injury or assault to yourself	0.1	0.1	0.2	0.4	0.5	0.1
High blood pressure	0.1	0.2	0.3	0.5	-0.5	0.3
Supplements: Glucosamine	0.1	0.2	0.4	-0.2	-0.2	-0.6
Number of incorrect matches in round	0.1	0.2	0.6	-0.7	0.1	0.2
Allergy	0.1	0.3	0.8	0.1	0.9	0.2
Neuroticism score	0.1	0.2	0.5	-0.1	0.7	0.3
Father’s age at death	0.1	0.1	0.3	-0.1	-0.4	0.5
Pulse rate	0.1	0.2	0.5	-0.2	-0.7	-0.2
Exposure to tobacco smoke at home	0.1	0.1	0.2	0.4	-0.0	-0.4
Birth weight	0.1	0.3	0.6	0.3	0.4	-0.8
Body fat percentage	0.1	0.4	0.9	-0.5	-0.2	0.9
Leg fat percentage (right)	0.1	0.5	1.1	-0.7	-0.0	1.0
Shortness of breath walking on level ground	0.1	0.1	0.3	-0.5	0.2	0.1
Mean time to correctly identify matches	0.1	0.1	0.2	-0.2	-0.5	-0.3
Illness, injury, bereavement, stress in last 2 years	0.1	0.2	0.4	-0.0	-0.4	-0.6
Hypertension (Self-reported)	0.1	0.4	0.5	0.4	-0.7	0.7
Arm fat percentage (left)	0.1	0.5	1.2	-0.5	0.0	1.1
Ever had bowel cancer screening	0.1	0.1	0.2	0.2	0.3	0.4
Friendships satisfaction	0.1	0.1	0.2	-0.4	0.3	0.4
Qualifications: nursing, teaching	0.1	0.2	0.5	0.7	0.4	-0.3
Commuting to job workplace: Walk	0.1	0.1	0.3	-0.6	0.0	0.0
Medication for cholesterol	0.1	0.1	0.2	0.4	-0.2	0.5
Back pain experienced in last month	0.1	0.1	0.2	-0.1	-0.2	0.5
Osteoporosis (self-reported)	0.1	0.1	0.3	-0.2	0.3	0.5
Osteoarthritis (self-reported)	0.1	0.2	0.5	0.1	0.1	0.7
Commuting to job workplace: Public transport	0.1	0.1	0.2	0.2	0.3	-0.4
Medication: Blood pressure	0.1	0.2	0.5	-0.7	-0.1	-0.2
Ever depressed for a whole week	0.1	0.1	0.2	0.3	0.5	0.0
Commuting to job workplace: Cycle	0.1	0.2	0.4	-0.6	-0.2	-0.2
Vascular/heart problems diagnosed by doctor	0.1	0.2	0.4	-0.1	0.6	-0.6
Heart attack/myocardial infarction (self-reported)	0.1	0.1	0.1	-0.3	-0.4	0.2
Alcohol drinker status: Previous	0.1	0.1	0.2	0.0	0.4	-0.5
Hair Pigment	0.0	0.1	0.2	0.1	0.2	-0.4
Frequency of depressed mood in last 2 weeks	0.0	0.1	0.1	-0.1	-0.2	0.4
Chronic bronchitis/emphysema (father)	0.0	0.0	0.0	0.1	-0.1	-0.2
Body mass index (BMI)	0.0	0.2	0.3	-0.2	0.4	0.5
Alcohol intake versus 10 years previously	0.0	0.0	0.1	0.3	-0.0	0.2
Hair/balding pattern: Pattern 4	0.0	0.0	0.0	-0.1	-0.1	0.2
Qualifications: O levels/GCSEs or equivalent	0.0	0.0	0.1	-0.2	0.3	0.1
Gout (self-reported)	0.0	0.0	0.1	-0.2	-0.1	0.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.0	0.0	0.1	-0.1	0.2	0.3
Medication: Atorvastatin	0.0	0.0	0.1	-0.1	0.3	-0.0

Hub : Genes

GZMA

Models

Trait associations