[Hub]/) : Traits : Impedance of whole body :

chr1:752,566-2,761,863

Best TWAS P=1.47e-15 · Best GWAS P=1.07e-16 conditioned to 0.588

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex SLC35E2 0.35 0.15 enet 24 0.17 1.0e-20 6.9 -6.4 1.9e-10 -0.71 0.99 0.01 FALSE
2 GTEx Adipose Subcutaneous C1orf86 0.15 0.05 enet 10 0.04 2.0e-04 3.0 5.7 1.6e-08 0.37 0.38 0.14 FALSE
3 GTEx Adipose Visceral Omentum RP1-283E3.4 0.26 0.05 enet 25 0.16 1.5e-08 1.5 6.0 1.5e-09 0.21 0.15 0.07 TRUE
4 GTEx Brain Caudate basal ganglia RP4-758J18.10 0.20 -0.01 lasso 5 0.03 5.6e-02 7.1 -5.3 1.2e-07 -0.50 0.03 0.30 FALSE
5 GTEx Brain Cerebellar Hemisphere NADK 0.18 0.11 lasso 7 0.09 3.1e-03 7.4 7.6 2.3e-14 0.85 0.02 0.70 FALSE
6 GTEx Brain Cerebellar Hemisphere RP5-890O3.9 0.24 0.02 lasso 9 0.02 1.3e-01 8.2 -8.0 1.5e-15 -0.91 0.01 0.75 TRUE
7 GTEx Cells Transformed fibroblasts CDK11B 0.10 0.06 lasso 4 0.05 2.1e-04 -1.9 6.0 1.5e-09 0.85 0.03 0.89 FALSE
8 GTEx Esophagus Mucosa TMEM52 0.17 0.18 lasso 2 0.20 2.9e-13 6.7 -6.8 8.2e-12 -0.83 0.99 0.01 FALSE
9 GTEx Heart Atrial Appendage NADK 0.19 0.00 lasso 5 0.00 3.1e-01 6.9 5.1 2.8e-07 0.62 0.03 0.32 FALSE
10 GTEx Lung NADK 0.07 0.03 lasso 3 0.02 8.5e-03 -6.3 7.4 1.3e-13 0.94 0.02 0.93 FALSE
11 GTEx Muscle Skeletal NADK 0.06 0.00 enet 9 0.00 1.3e-01 7.4 7.5 4.3e-14 0.79 0.05 0.85 FALSE
12 GTEx Muscle Skeletal TMEM52 0.11 0.08 lasso 6 0.10 7.2e-10 7.7 -7.5 7.5e-14 -0.84 0.35 0.65 FALSE
13 GTEx Pancreas TMEM52 0.19 0.00 enet 30 0.00 2.6e-01 1.4 5.5 3.1e-08 0.59 0.02 0.76 FALSE
14 GTEx Pituitary NADK 0.21 0.09 enet 15 0.07 9.5e-03 7.7 6.2 5.5e-10 0.67 0.03 0.56 FALSE
15 GTEx Skin Not Sun Exposed Suprapubic TMEM52 0.19 0.18 lasso 4 0.14 2.6e-08 -6.3 -6.9 5.0e-12 -0.92 0.03 0.97 FALSE
16 GTEx Skin Sun Exposed Lower leg TMEM52 0.17 0.14 lasso 7 0.15 2.0e-12 -7.3 -7.4 1.0e-13 -0.92 0.05 0.95 FALSE
17 GTEx Spleen TMEM52 0.47 0.21 lasso 5 0.22 2.3e-06 3.5 5.2 2.1e-07 0.58 0.25 0.36 FALSE
18 ROSMAP Brain Pre-frontal Cortex C1orf222 0.11 0.14 enet 18 0.14 1.8e-17 4.7 -6.9 6.3e-12 -0.70 1.00 0.00 FALSE
19 ROSMAP Brain Pre-frontal Cortex MMP23B 0.05 0.04 lasso 2 0.03 1.9e-04 6.9 6.8 7.4e-12 0.80 0.06 0.93 FALSE
20 ROSMAP Brain Pre-frontal Cortex SLC35E2 0.03 0.00 blup 291 0.01 1.4e-02 1.4 -5.4 8.0e-08 -0.73 0.03 0.66 FALSE
21 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma SLC35E2 0.03 0.03 blup 35 0.01 7.0e-02 8.1 7.1 1.4e-12 0.95 0.01 0.99 FALSE
22 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma TMEM52 0.02 0.01 blup 37 0.02 6.6e-03 7.0 -7.2 5.2e-13 -0.91 0.01 0.81 FALSE
23 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma SLC35E2 0.03 0.00 blup 34 0.01 5.3e-02 7.1 -7.0 3.1e-12 -0.82 0.02 0.55 FALSE
24 The Cancer Genome Atlas Brain Lower Grade Glioma SLC35E2 0.04 0.03 lasso 5 0.05 1.4e-06 7.1 -6.1 1.2e-09 -0.79 0.02 0.98 FALSE