[Hub]/) : Traits : Impedance of whole body : ← →

chr1:8,655,495-12,013,869

Best TWAS P=1.15e-15 · Best GWAS P=1.09e-13 conditioned to 6.83e-12

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
9	GTEx	Esophagus Mucosa	KIF1B	0.10	0.00	enet	17	0.01	1.2e-01	-5.3	-8.0	1.1e-15	0.08	0.17	0.25	TRUE
14	GTEx	Thyroid	RP4-635E18.7	0.07	0.02	lasso	2	0.01	5.5e-02	-5.8	-6.7	2.2e-11	0.03	0.17	0.11	TRUE
20	YFS	Blood	SPSB1	0.03	0.03	bslmm	425	0.03	1.5e-09	5.9	5.8	5.8e-09	0.04	0.18	0.82	TRUE
11	GTEx	Muscle Skeletal	KIF1B	0.04	0.08	lasso	1	0.07	3.1e-07	-6.4	-6.4	1.6e-10	-0.06	0.83	0.16	FALSE
16	NTR	Blood	KIF1B	0.11	0.08	enet	11	0.09	3.7e-28	6.9	6.1	1.2e-09	-0.06	0.04	0.96	FALSE
13	GTEx	Thyroid	KIF1B	0.13	0.14	lasso	5	0.16	5.3e-12	-6.4	-6.0	1.5e-09	-0.07	0.90	0.10	FALSE
18	ROSMAP	Brain Pre-frontal Cortex	MTOR	0.07	0.05	bslmm	423	0.04	2.0e-06	-5.2	-6.0	2.0e-09	-0.01	1.00	0.00	FALSE
19	YFS	Blood	KIF1B	0.30	0.26	enet	49	0.29	7.8e-97	6.9	5.9	3.4e-09	-0.11	0.05	0.95	FALSE
3	GTEx	Brain Caudate basal ganglia	KIF1B	0.25	0.00	lasso	5	0.02	1.1e-01	-4.4	-5.9	3.5e-09	0.02	0.06	0.14	FALSE
6	GTEx	Brain Cerebellum	RP4-635E18.7	0.17	0.17	lasso	5	0.09	1.3e-03	-5.8	-5.9	4.2e-09	0.02	0.38	0.04	FALSE
10	GTEx	Lung	EXOSC10	0.11	0.07	lasso	4	0.05	1.2e-04	-5.8	-5.7	1.4e-08	0.02	0.87	0.02	FALSE
5	GTEx	Brain Cerebellum	EXOSC10	0.33	0.16	lasso	6	0.18	3.8e-06	-5.8	-5.7	1.6e-08	0.00	0.77	0.02	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	EXOSC10	0.06	0.06	lasso	2	0.06	4.9e-08	-5.7	-5.6	1.7e-08	0.01	0.98	0.02	FALSE
1	CommonMind	Brain Pre-frontal Cortex	EXOSC10	0.06	0.08	lasso	2	0.07	6.8e-09	-5.7	-5.6	1.8e-08	0.00	0.98	0.02	FALSE
15	METSIM	Adipose	MTOR	0.04	0.02	bslmm	434	0.02	1.5e-04	-5.2	-5.6	2.0e-08	0.08	0.89	0.01	FALSE
12	GTEx	Nerve Tibial	KIF1B	0.10	0.07	lasso	6	0.04	8.5e-04	-5.2	-5.6	2.5e-08	-0.09	0.89	0.05	FALSE
8	GTEx	Cells Transformed fibroblasts	UBE4B	0.09	0.00	enet	21	0.00	1.4e-01	-5.3	-5.6	2.6e-08	-0.01	0.05	0.10	FALSE
22	The Cancer Genome Atlas	Brain Lower Grade Glioma	MTOR	0.03	0.01	blup	54	0.02	5.9e-03	-5.5	-5.6	2.6e-08	-0.01	0.03	0.74	FALSE
21	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	MTOR	0.02	0.02	blup	54	0.02	5.4e-03	-5.5	-5.5	3.1e-08	0.00	0.05	0.74	FALSE
4	GTEx	Brain Cerebellar Hemisphere	EXOSC10	0.23	0.10	lasso	3	0.12	6.4e-04	-5.0	-5.5	3.6e-08	0.02	0.19	0.05	FALSE
2	GTEx	Adipose Visceral Omentum	RP4-635E18.7	0.19	0.08	lasso	6	0.05	9.0e-04	-5.7	-5.3	1.1e-07	0.01	0.44	0.03	FALSE
7	GTEx	Brain Cortex	RP4-635E18.7	0.17	0.05	lasso	4	0.07	6.4e-03	-5.2	-5.2	2.1e-07	0.00	0.18	0.04	FALSE