[Hub]/) : Traits : Impedance of whole body :

chr1:8,655,495-12,013,869

Best TWAS P=1.15e-15 · Best GWAS P=1.09e-13 conditioned to 6.83e-12

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex EXOSC10 0.06 0.08 lasso 2 0.07 6.8e-09 -5.7 -5.6 1.8e-08 0.00 0.98 0.02 FALSE
2 GTEx Adipose Visceral Omentum RP4-635E18.7 0.19 0.08 lasso 6 0.05 9.0e-04 -5.7 -5.3 1.1e-07 0.01 0.44 0.03 FALSE
3 GTEx Brain Caudate basal ganglia KIF1B 0.25 0.00 lasso 5 0.02 1.1e-01 -4.4 -5.9 3.5e-09 0.02 0.06 0.14 FALSE
4 GTEx Brain Cerebellar Hemisphere EXOSC10 0.23 0.10 lasso 3 0.12 6.4e-04 -5.0 -5.5 3.6e-08 0.02 0.19 0.05 FALSE
5 GTEx Brain Cerebellum EXOSC10 0.33 0.16 lasso 6 0.18 3.8e-06 -5.8 -5.7 1.6e-08 0.00 0.77 0.02 FALSE
6 GTEx Brain Cerebellum RP4-635E18.7 0.17 0.17 lasso 5 0.09 1.3e-03 -5.8 -5.9 4.2e-09 0.02 0.38 0.04 FALSE
7 GTEx Brain Cortex RP4-635E18.7 0.17 0.05 lasso 4 0.07 6.4e-03 -5.2 -5.2 2.1e-07 0.00 0.18 0.04 FALSE
8 GTEx Cells Transformed fibroblasts UBE4B 0.09 0.00 enet 21 0.00 1.4e-01 -5.3 -5.6 2.6e-08 -0.01 0.05 0.10 FALSE
9 GTEx Esophagus Mucosa KIF1B 0.10 0.00 enet 17 0.01 1.2e-01 -5.3 -8.0 1.1e-15 0.08 0.17 0.25 TRUE
10 GTEx Lung EXOSC10 0.11 0.07 lasso 4 0.05 1.2e-04 -5.8 -5.7 1.4e-08 0.02 0.87 0.02 FALSE
11 GTEx Muscle Skeletal KIF1B 0.04 0.08 lasso 1 0.07 3.1e-07 -6.4 -6.4 1.6e-10 -0.06 0.83 0.16 FALSE
12 GTEx Nerve Tibial KIF1B 0.10 0.07 lasso 6 0.04 8.5e-04 -5.2 -5.6 2.5e-08 -0.09 0.89 0.05 FALSE
13 GTEx Thyroid KIF1B 0.13 0.14 lasso 5 0.16 5.3e-12 -6.4 -6.0 1.5e-09 -0.07 0.90 0.10 FALSE
14 GTEx Thyroid RP4-635E18.7 0.07 0.02 lasso 2 0.01 5.5e-02 -5.8 -6.7 2.2e-11 0.03 0.17 0.11 TRUE
15 METSIM Adipose MTOR 0.04 0.02 bslmm 434 0.02 1.5e-04 -5.2 -5.6 2.0e-08 0.08 0.89 0.01 FALSE
16 NTR Blood KIF1B 0.11 0.08 enet 11 0.09 3.7e-28 6.9 6.1 1.2e-09 -0.06 0.04 0.96 FALSE
17 ROSMAP Brain Pre-frontal Cortex EXOSC10 0.06 0.06 lasso 2 0.06 4.9e-08 -5.7 -5.6 1.7e-08 0.01 0.98 0.02 FALSE
18 ROSMAP Brain Pre-frontal Cortex MTOR 0.07 0.05 bslmm 423 0.04 2.0e-06 -5.2 -6.0 2.0e-09 -0.01 1.00 0.00 FALSE
19 YFS Blood KIF1B 0.30 0.26 enet 49 0.29 7.8e-97 6.9 5.9 3.4e-09 -0.11 0.05 0.95 FALSE
20 YFS Blood SPSB1 0.03 0.03 bslmm 425 0.03 1.5e-09 5.9 5.8 5.8e-09 0.04 0.18 0.82 TRUE
21 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma MTOR 0.02 0.02 blup 54 0.02 5.4e-03 -5.5 -5.5 3.1e-08 0.00 0.05 0.74 FALSE
22 The Cancer Genome Atlas Brain Lower Grade Glioma MTOR 0.03 0.01 blup 54 0.02 5.9e-03 -5.5 -5.6 2.6e-08 -0.01 0.03 0.74 FALSE