Best TWAS P=3.89e-08 · Best GWAS P=1.39e-07 conditioned to 0.0853
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | FAN1 | 0.09 | 0.12 | lasso | 4 | 0.12 | 3.9e-14 | -4.8 | -5.3 | 1.3e-07 | -0.71 | 0.03 | 0.96 | FALSE |
2 | GTEx | Adipose Subcutaneous | FAN1 | 0.10 | 0.04 | lasso | 6 | 0.08 | 4.4e-07 | -4.2 | -5.5 | 3.9e-08 | -0.75 | 0.04 | 0.94 | TRUE |