[Hub]/) : Traits : Impedance of whole body :

chr14:101,910,147-104,866,687

Best TWAS P=1.3e-10 · Best GWAS P=3.98e-11 conditioned to 0.0311

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex WDR20 0.14 0.18 lasso 3 0.18 9.0e-21 -5.8 -5.6 1.9e-08 0.90 0.27 0.73 FALSE
2 GTEx Adipose Subcutaneous MARK3 0.12 0.05 lasso 3 0.06 2.5e-05 5.4 5.6 1.9e-08 0.05 0.02 0.98 FALSE
3 GTEx Adipose Visceral Omentum KLC1 0.06 0.02 lasso 2 0.00 2.2e-01 5.1 -5.4 5.9e-08 0.01 0.08 0.46 FALSE
4 GTEx Artery Aorta KLC1 0.10 0.14 lasso 3 0.14 6.1e-08 5.1 -5.3 1.3e-07 0.03 0.06 0.94 FALSE
5 GTEx Artery Tibial TRMT61A 0.07 0.07 lasso 3 0.06 2.4e-05 5.2 5.5 2.9e-08 0.05 0.02 0.98 FALSE
6 GTEx Brain Cerebellum ZNF839 0.22 0.04 lasso 4 0.07 5.2e-03 -4.1 -5.3 1.2e-07 0.54 0.09 0.26 FALSE
7 GTEx Breast Mammary Tissue MARK3 0.12 0.11 lasso 2 0.08 3.9e-05 5.4 5.5 5.1e-08 0.02 0.01 0.98 FALSE
8 GTEx Breast Mammary Tissue (Male) MARK3 0.08 0.00 enet 9 -0.01 7.2e-01 5.4 5.8 5.4e-09 0.03 0.02 0.47 TRUE
9 GTEx Cells Transformed fibroblasts APOPT1 0.14 0.12 lasso 3 0.10 6.4e-08 5.0 5.2 2.0e-07 -0.02 0.08 0.91 FALSE
10 GTEx Esophagus Muscularis MOK 0.13 0.02 lasso 5 0.01 4.1e-02 -6.1 5.3 9.9e-08 -0.76 0.04 0.73 FALSE
11 GTEx Lung MARK3 0.06 0.02 lasso 3 0.01 6.6e-02 5.4 5.7 1.1e-08 0.03 0.02 0.96 FALSE
12 GTEx Lung CKB 0.07 0.01 lasso 2 0.01 3.4e-02 5.1 5.7 1.0e-08 0.02 0.02 0.93 FALSE
13 GTEx Pituitary MARK3 0.21 0.27 enet 8 0.25 4.9e-07 5.4 5.6 1.9e-08 0.02 0.01 0.98 FALSE
14 GTEx Prostate MARK3 0.18 0.22 enet 11 0.20 8.0e-06 5.5 5.3 1.2e-07 0.02 0.01 0.97 FALSE
15 GTEx Skin Not Sun Exposed Suprapubic MARK3 0.16 0.10 lasso 3 0.10 6.7e-06 5.4 5.7 1.3e-08 0.02 0.01 0.99 FALSE
16 GTEx Skin Sun Exposed Lower leg MARK3 0.10 0.09 enet 13 0.08 7.5e-07 5.4 5.3 1.5e-07 0.03 0.01 0.99 FALSE
17 GTEx Stomach MARK3 0.10 0.09 lasso 2 0.04 4.5e-03 5.4 5.4 8.3e-08 0.03 0.01 0.96 FALSE
18 GTEx Stomach TRMT61A 0.12 0.11 lasso 5 0.08 1.2e-04 5.4 5.5 5.0e-08 0.02 0.01 0.98 FALSE
19 GTEx Thyroid ZNF839 0.10 0.08 enet 9 0.13 5.6e-10 -5.7 -5.7 1.2e-08 0.64 0.67 0.32 FALSE
20 GTEx Thyroid MARK3 0.38 0.48 lasso 4 0.48 2.8e-41 5.4 5.4 5.6e-08 0.02 0.01 0.99 FALSE
21 METSIM Adipose WDR20 0.03 0.04 lasso 8 0.04 1.6e-06 -6.4 6.4 1.3e-10 -0.92 0.03 0.97 TRUE
22 YFS Blood KLC1 0.01 0.01 blup 389 0.01 1.0e-03 4.6 -5.6 1.7e-08 -0.02 0.08 0.79 FALSE
23 The Cancer Genome Atlas Colon Adenocarcinoma RAGE 0.08 0.09 blup 60 0.09 7.3e-06 -6.2 5.7 1.2e-08 -0.82 0.02 0.97 FALSE
24 The Cancer Genome Atlas Lung Adenocarcinoma RAGE 0.04 0.01 blup 60 0.03 2.5e-04 -6.2 5.8 8.6e-09 -0.75 0.02 0.98 FALSE
25 The Cancer Genome Atlas Lung Squamous Cell Carcinoma TRMT61A 0.02 0.00 blup 34 0.01 6.2e-02 -3.4 5.3 1.4e-07 0.05 0.01 0.70 FALSE
26 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma BAG5 0.08 0.09 lasso 2 0.08 3.7e-04 5.4 5.4 6.3e-08 0.03 0.00 0.96 FALSE
27 The Cancer Genome Atlas Prostate Adenocarcinoma C14orf153 0.09 0.08 blup 38 0.09 6.2e-10 5.0 5.3 9.5e-08 -0.02 0.02 0.98 FALSE
28 The Cancer Genome Atlas Prostate Adenocarcinoma MARK3 0.07 0.06 enet 7 0.08 1.0e-08 4.9 5.5 4.2e-08 0.05 0.03 0.97 FALSE
29 The Cancer Genome Atlas Prostate Adenocarcinoma TRMT61A 0.03 0.01 blup 32 0.01 1.4e-02 5.2 5.2 2.2e-07 0.03 0.00 0.64 FALSE
30 The Cancer Genome Atlas Testicular Germ Cell Tumors RAGE 0.09 0.00 blup 58 0.03 3.0e-02 -3.5 5.1 3.0e-07 -0.76 0.02 0.64 FALSE
31 The Cancer Genome Atlas Thyroid Carcinoma MARK3 0.10 0.03 blup 61 0.03 4.0e-04 4.9 5.3 9.9e-08 -0.01 0.01 0.58 FALSE