Best TWAS P=1.52e-07 · Best GWAS P=1.38e-07 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Aorta | RHOT1 | 0.11 | 0.00 | enet | 20 | 0.01 | 7.8e-02 | 3.4 | -5.1 | 2.8e-07 | 0.02 | 0.03 | 0.49 | TRUE |
2 | GTEx | Breast Mammary Tissue (Male) | CTC-542B22.2 | 0.21 | 0.07 | enet | 47 | 0.05 | 3.1e-02 | 3.4 | 5.2 | 2.0e-07 | -0.25 | 0.06 | 0.10 | FALSE |
3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | EVI2A | 0.03 | 0.03 | blup | 38 | 0.03 | 6.9e-07 | -5.0 | 5.2 | 1.5e-07 | -0.97 | 0.02 | 0.98 | TRUE |