Best TWAS P=6e-08 · Best GWAS P=2e-08 conditioned to 1.61e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | DHRS11 | 0.12 | 0.08 | lasso | 2 | 0.06 | 5.1e-05 | -4.9 | -5.1 | 3.0e-07 | 0.05 | 0.02 | 0.97 | FALSE |
| 2 | NTR | Blood | GGNBP2 | 0.03 | 0.02 | bslmm | 331 | 0.02 | 7.7e-07 | 4.4 | 5.4 | 6.0e-08 | -0.07 | 0.04 | 0.94 | TRUE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | ZNHIT3 | 0.05 | 0.03 | enet | 4 | 0.04 | 4.7e-05 | -4.9 | -5.2 | 2.3e-07 | 0.04 | 0.01 | 0.98 | FALSE |