[Hub]/) : Traits : Impedance of whole body : ← →

chr2:23,453,834-26,088,769

Best TWAS P=2.51e-11 · Best GWAS P=3.28e-12 conditioned to 4.02e-10

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	UBXN2A	0.22	0.18	enet	28	0.24	3.0e-28	6.1	-6.0	1.6e-09	0.05	0.03	0.97	FALSE
2	GTEx	Cells EBV-transformed lymphocytes	PFN4	0.18	0.13	lasso	12	0.12	8.9e-05	3.9	5.3	1.1e-07	-0.03	0.09	0.73	FALSE
3	GTEx	Cells EBV-transformed lymphocytes	RP11-443B20.1	0.13	0.13	enet	9	0.05	9.2e-03	-5.0	5.5	4.5e-08	0.05	0.31	0.17	FALSE
4	GTEx	Esophagus Gastroesophageal Junction	PFN4	0.13	0.01	lasso	12	0.01	9.7e-02	6.4	5.8	8.5e-09	-0.06	0.07	0.42	FALSE
5	GTEx	Heart Atrial Appendage	UBXN2A	0.08	0.02	lasso	3	0.02	5.2e-02	6.7	6.7	2.9e-11	-0.04	0.02	0.94	FALSE
6	GTEx	Heart Atrial Appendage	PFN4	0.22	0.06	lasso	7	0.10	2.8e-05	-2.2	5.3	1.2e-07	-0.05	0.10	0.86	FALSE
7	GTEx	Nerve Tibial	ADCY3	0.09	0.05	enet	6	0.03	2.2e-03	-3.9	5.4	7.8e-08	0.01	0.85	0.12	FALSE
8	METSIM	Adipose	POMC	0.18	0.06	lasso	9	0.09	5.5e-13	2.9	5.1	2.7e-07	-0.09	0.97	0.03	FALSE
9	METSIM	Adipose	UBXN2A	0.07	0.03	bslmm	403	0.06	5.3e-10	3.9	5.2	1.7e-07	-0.02	0.17	0.83	FALSE
10	ROSMAP	Brain Pre-frontal Cortex	UBXN2A	0.03	0.01	lasso	4	0.02	2.2e-03	6.7	-6.6	4.9e-11	0.07	0.02	0.95	FALSE
11	YFS	Blood	POMC	0.35	0.05	enet	71	0.19	5.7e-59	7.0	6.6	5.1e-11	-0.06	0.00	1.00	TRUE
12	The Cancer Genome Atlas	Breast Invasive Carcinoma	POMC	0.08	0.05	lasso	3	0.06	2.6e-12	3.2	5.5	4.9e-08	-0.05	0.63	0.37	FALSE
13	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	EFR3B	0.03	0.05	lasso	1	0.04	1.9e-05	5.2	5.2	1.7e-07	0.02	0.09	0.85	FALSE
14	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	POMC	0.16	0.05	blup	39	0.11	2.4e-12	7.0	6.2	7.5e-10	-0.07	0.00	1.00	FALSE
15	The Cancer Genome Atlas	Brain Lower Grade Glioma	UBXN2A	0.04	0.04	lasso	1	0.03	1.4e-04	6.7	-6.7	2.5e-11	0.05	0.01	0.98	TRUE
16	The Cancer Genome Atlas	Lung Adenocarcinoma	POMC	0.14	0.04	enet	7	0.08	5.3e-10	3.2	5.4	5.6e-08	-0.08	0.10	0.89	FALSE
17	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	POMC	0.19	0.01	blup	38	0.05	1.5e-04	7.0	6.2	4.3e-10	-0.07	0.00	0.85	FALSE
18	The Cancer Genome Atlas	Prostate Adenocarcinoma	POMC	0.11	0.08	enet	7	0.09	1.6e-09	3.2	6.0	2.7e-09	-0.06	0.13	0.87	FALSE
19	The Cancer Genome Atlas	Stomach Adenocarcinoma	POMC	0.14	0.00	blup	40	0.02	2.2e-02	3.6	5.8	8.6e-09	-0.04	0.00	0.62	FALSE