TWAS hub - POMC

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.3820	0.0530	0.0e+00	0.216	0.241	0.259	0.229	0.263	8.8e-26	4.5e-29	2.2e-31	1.9e-27	6.9e-32
2	GTEx	Brain Cerebellum	0.8990	0.0380	5.0e-05	0.064	NA	0.451	NA	0.009	6.1e-03	NA	6.6e-15	NA	1.7e-01
3	GTEx	Muscle Skeletal	0.3827	0.0941	1.5e-06	0.102	NA	0.073	NA	0.091	3.7e-10	NA	1.2e-07	NA	2.9e-09
4	GTEx	Stomach	0.7460	0.0550	7.8e-07	-0.006	NA	0.037	NA	-0.006	8.4e-01	NA	6.8e-03	NA	8.7e-01
5	METSIM	Adipose	0.1765	0.0512	1.7e-08	0.061	0.050	0.076	0.076	0.087	1.9e-09	5.6e-08	1.6e-11	1.8e-11	5.5e-13
6	ROSMAP	Brain Pre-frontal Cortex	0.3376	0.0496	0.0e+00	0.209	0.190	0.219	0.231	0.235	2.2e-26	7.5e-24	1.1e-27	3.0e-29	8.8e-30
7	YFS	Blood	0.3526	0.0444	0.0e+00	0.055	0.177	0.187	0.144	0.163	2.0e-17	1.3e-55	5.7e-59	1.0e-44	8.6e-51
8	TCGA	Breast Invasive Carcinoma	0.0777	0.0287	6.9e-09	0.048	0.054	0.059	NA	0.060	3.9e-10	3.0e-11	3.1e-12	NA	2.6e-12
9	TCGA	Head and Neck Squamous Cell Carcinoma	0.0581	0.0380	4.3e-03	0.000	0.018	0.034	NA	0.011	3.1e-01	3.5e-03	9.3e-05	NA	1.8e-02
10	TCGA	Kidney Renal Clear Cell Carcinoma	0.1552	0.0471	5.2e-10	0.046	0.110	0.103	NA	0.106	6.4e-06	2.4e-12	1.3e-11	NA	6.7e-12
11	TCGA	Kidney Renal Papillary Cell Carcinoma	0.4340	0.1320	1.8e-04	0.113	0.007	0.100	NA	0.111	5.2e-07	1.2e-01	2.5e-06	NA	6.6e-07
12	TCGA	Brain Lower Grade Glioma	0.2615	0.0914	3.2e-09	0.116	0.104	0.103	NA	0.107	4.5e-13	7.1e-12	9.7e-12	NA	4.1e-12
13	TCGA	Lung Adenocarcinoma	0.1425	0.0570	1.2e-08	0.038	0.082	0.084	NA	0.075	2.5e-05	7.8e-10	5.3e-10	NA	3.8e-09
14	TCGA	Ovarian Serous Cystadenocarcinoma	0.1860	0.0920	4.4e-04	0.014	0.054	0.041	NA	0.034	3.5e-02	1.5e-04	8.5e-04	NA	2.4e-03
15	TCGA	Pancreatic Adenocarcinoma	0.2180	0.1010	3.2e-03	0.047	0.029	0.025	NA	0.028	4.6e-03	2.1e-02	3.2e-02	NA	2.3e-02
16	TCGA	Prostate Adenocarcinoma	0.1081	0.0402	1.1e-07	0.079	0.078	0.088	NA	0.086	1.1e-08	1.6e-08	1.6e-09	NA	2.7e-09
17	TCGA	Stomach Adenocarcinoma	0.1420	0.0750	2.7e-03	-0.004	0.016	0.007	NA	0.008	8.4e-01	2.2e-02	9.1e-02	NA	8.3e-02
18	TCGA	Thyroid Carcinoma	0.1340	0.0590	8.9e-05	0.044	0.029	0.018	NA	0.031	3.8e-05	7.5e-04	6.0e-03	NA	4.7e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	3	5	6	7	8	9	10	11	12	13	14	15	16	17	18
Comparative body size at age 10	19.0	52.5	136.9	-3.6	-7.8	-5.7	-2.5	-11.2	-8.8	-11.5	-7.9	-2.7	-2.2	-9.3	-11.7	-7.6	-10.7	-4.6	-2.4
Body mass index (BMI)	9.7	41.3	94.7	-4.7	-4.5	-5.8	-3.7	-9.7	-7.9	-8.1	-6.8	-4.2	-3.6	-8.6	-8.9	-7.5	-8.9	-6.9	-4.1
BMI	9.4	54.6	123.2	-5.3	-4.9	-7.1	-4.4	-11.1	-9.1	-9.2	-7.9	-4.9	-4.1	-10.1	-10.2	-8.3	-10.2	-8.1	-4.6
Arm fat percentage (left)	7.7	30.9	69.7	-3.3	-3.9	-4.3	-2.6	-8.3	-7.1	-8.1	-5.4	-3.1	-2.8	-7.8	-7.8	-7.0	-8.1	-5.3	-3.1
Arm fat percentage (right)	7.6	30.0	67.4	-3.3	-3.8	-4.4	-2.6	-8.2	-7.0	-7.8	-5.3	-3.0	-2.8	-7.8	-7.7	-7.0	-8.0	-5.2	-3.1
Arm fat mass (left)	7.2	29.7	63.0	-3.8	-2.9	-4.1	-3.3	-7.3	-6.9	-7.3	-5.2	-3.7	-3.6	-7.9	-6.8	-7.6	-7.8	-5.7	-4.1
Arm fat mass (right)	7.0	28.9	61.5	-3.6	-2.7	-4.0	-3.1	-7.4	-6.8	-7.2	-5.1	-3.5	-3.4	-7.8	-6.9	-7.5	-7.8	-5.6	-3.9
Leg fat percentage (left)	6.3	22.6	54.5	-2.7	-2.8	-4.0	-2.1	-7.4	-6.0	-6.6	-4.7	-2.6	-2.0	-6.8	-7.1	-5.8	-6.8	-5.0	-2.3
Leg fat percentage (right)	6.2	22.6	51.4	-2.6	-2.6	-3.8	-2.0	-7.2	-6.0	-6.8	-4.6	-2.5	-2.1	-6.9	-7.1	-5.9	-6.8	-4.8	-2.4
Leg fat mass (right)	6.2	24.0	52.1	-3.4	-2.2	-3.9	-2.8	-6.8	-6.1	-6.3	-4.7	-3.2	-2.9	-7.2	-6.3	-6.8	-6.9	-5.5	-3.5
Leg fat mass (left)	6.2	24.1	51.1	-3.4	-2.3	-4.0	-2.9	-6.9	-6.1	-6.2	-4.7	-3.3	-2.9	-7.2	-6.3	-6.8	-6.9	-5.6	-3.5
Whole body fat mass	5.0	21.0	49.3	-3.0	-1.6	-3.2	-2.7	-5.9	-5.8	-6.1	-4.0	-3.1	-3.1	-7.0	-5.5	-6.9	-6.6	-5.0	-3.5
Body fat percentage	4.9	19.2	44.0	-2.2	-2.0	-3.1	-1.8	-6.5	-5.6	-6.5	-3.9	-2.3	-2.0	-6.6	-6.1	-6.0	-6.4	-4.4	-2.4
Hip circumference	4.7	20.3	42.8	-3.5	-1.6	-3.1	-3.2	-5.6	-5.7	-5.5	-4.2	-3.8	-3.5	-6.5	-4.8	-6.3	-6.4	-5.4	-4.1
Waist circumference	4.6	16.7	44.1	-2.8	-1.4	-3.4	-2.4	-6.1	-5.1	-5.3	-2.9	-2.3	-2.6	-6.2	-4.6	-6.6	-5.7	-4.2	-2.9
Impedance of whole body	4.5	22.9	43.2	4.9	4.3	5.1	4.0	6.6	5.5	4.0	6.2	4.0	3.4	5.4	6.2	4.7	6.0	5.8	3.8
Impedance of leg (right)	4.2	20.2	44.0	4.5	4.4	4.8	3.5	6.6	5.1	3.6	5.7	3.6	3.0	5.0	5.7	4.5	5.6	5.5	3.3
Impedance of leg (left)	4.2	20.6	41.7	4.4	4.3	4.6	3.5	6.5	5.2	4.2	5.7	3.5	3.1	5.2	5.9	4.7	5.8	5.4	3.5
Ever smoked	4.0	7.0	17.1	-3.6	-1.0	-4.1	-3.4	-3.0	-2.6	-1.9	-2.5	-2.8	-2.7	-2.7	-2.1	-2.6	-2.6	-3.0	-2.7
Weight	3.8	18.7	52.8	-3.3	-0.5	-2.3	-3.2	-4.3	-5.4	-5.1	-3.4	-3.4	-3.8	-6.7	-4.2	-7.3	-6.0	-5.1	-4.5
Worrier / anxious feelings	3.7	6.9	16.5	1.9	1.7	2.1	1.8	4.0	3.0	3.6	3.0	2.1	1.5	3.4	4.1	2.9	3.1	2.7	1.5
Mouth/teeth dental problems: Loose teeth	3.7	4.4	9.9	-2.3	-0.9	-2.6	-2.1	-3.1	-2.9	-3.1	-1.6	-1.9	-1.9	-2.3	-2.5	-1.0	-2.5	-1.6	-1.8
Body Mass Index (BMI) (2010)	3.6	5.0	9.1	-1.3	-2.5	-0.7	-1.6	-2.8	-2.9	-2.8	-2.2	-1.8	-1.9	-2.6	-3.0	-2.9	-3.0	-2.3	-1.8
Trunk fat mass	3.6	15.5	39.9	-2.4	-0.7	-2.3	-2.2	-4.9	-5.1	-5.4	-3.0	-2.5	-2.7	-6.3	-4.5	-6.3	-5.8	-4.2	-3.1
Nervous feelings	3.5	6.6	15.8	2.2	1.1	1.3	2.2	3.1	3.3	4.0	2.5	2.3	2.4	3.5	3.4	2.7	3.2	2.1	2.5
Commuting to job workplace: Car/motor vehicle	3.5	4.0	7.3	-2.2	-0.9	-1.4	-2.2	-1.4	-2.4	-1.5	-2.1	-2.2	-2.1	-2.4	-2.2	-2.7	-2.4	-2.6	-2.3
Height	3.3	63.9	265.7	5.8	11.8	11.5	2.9	16.3	7.8	8.8	10.3	3.3	0.3	5.5	13.5	0.3	8.6	5.2	-0.6
Impedance of arm (left)	3.2	14.8	29.7	4.3	3.1	4.9	3.4	5.5	4.2	2.4	5.0	3.4	2.7	4.1	4.9	3.3	4.4	4.9	2.9
Trunk fat percentage	3.1	12.6	31.6	-1.6	-1.1	-2.2	-1.3	-5.1	-4.6	-5.5	-2.7	-1.7	-1.7	-5.6	-4.7	-5.4	-5.3	-3.4	-2.0
Past tobacco smoking	3.1	5.8	11.4	3.0	0.4	3.4	2.7	2.6	2.7	2.3	2.4	2.4	2.2	2.9	2.3	2.4	2.6	3.0	2.3
Medication: Ramipril	3.1	3.9	10.4	-2.2	-0.4	-3.2	-1.8	-2.4	-2.2	-1.8	-2.0	-1.6	-1.1	-2.4	-2.9	-2.1	-2.2	-2.4	-1.0
Impedance of arm (right)	2.9	13.7	29.3	3.8	2.9	4.2	3.1	5.4	4.1	2.8	4.8	3.2	2.5	4.2	4.9	3.4	4.3	4.9	2.8
Reason for reducing amount of alcohol drunk: Health precaution	2.9	3.4	10.2	1.5	1.4	1.2	1.2	2.5	1.9	2.5	2.6	1.8	1.0	2.0	3.2	1.2	1.9	2.4	1.3
Standing height	2.7	26.6	114.5	2.6	8.4	7.1	0.7	10.7	4.4	5.7	6.8	1.1	-1.0	3.0	9.3	-0.5	5.2	2.8	-1.5
Pulse wave reflection index	2.7	3.3	8.2	-2.1	-1.1	-1.4	-2.5	-0.9	-1.9	-1.2	-1.4	-2.2	-2.6	-1.9	-0.9	-2.5	-1.8	-1.9	-2.9
Breast Cancer	2.6	6.3	16.6	-1.5	-3.5	-2.5	-0.9	-4.1	-2.9	-2.9	-2.9	-0.9	-0.8	-2.7	-3.8	-2.7	-3.5	-2.4	-1.2
Comparative height size at age 10	2.6	14.1	50.4	2.5	5.7	5.0	1.4	7.1	3.7	5.2	5.0	1.4	0.3	2.5	6.7	-0.7	3.9	1.9	0.0
High blood pressure (mother)	2.5	3.5	7.5	-2.1	-1.4	-1.2	-2.1	-0.8	-2.0	-1.6	-2.0	-2.3	-2.1	-2.3	-2.2	-2.7	-2.1	-1.8	-2.1
Forced expiratory volume in 1-second (FEV1), predicted	2.4	4.9	18.9	1.7	3.0	2.8	1.4	4.3	2.3	1.9	2.9	1.3	0.6	1.4	4.0	0.5	2.3	2.1	0.2
Commuting to job workplace: Public transport	2.4	2.9	5.6	1.6	0.3	0.9	1.6	1.5	2.1	1.3	2.0	1.7	1.6	2.2	2.3	2.3	2.4	2.1	1.7
Number of operations (self-reported)	2.4	3.5	13.0	-1.3	1.6	-0.5	-1.4	-2.1	-2.0	-0.4	-1.4	-1.9	-1.6	-2.5	-2.5	-2.8	-1.8	-3.6	-1.8
Diabetes (mother)	2.3	2.9	6.0	1.3	1.1	0.3	1.4	1.3	1.7	2.4	2.1	1.4	1.6	2.4	2.0	2.3	1.6	2.4	2.2
Illnesses of siblings: Diabetes	2.3	2.8	6.0	1.8	1.0	0.9	2.1	1.4	1.9	2.4	1.5	1.6	2.2	2.1	1.1	2.0	2.0	0.9	2.4
Arm fat-free mass (left)	2.3	11.4	35.0	-3.3	0.8	-1.7	-3.5	-1.7	-3.8	-2.2	-2.4	-3.6	-4.1	-4.9	-2.0	-5.9	-3.9	-4.5	-4.7
Worry (Nagel 2018)	2.2	4.6	13.5	1.3	0.4	1.2	1.3	3.3	2.7	3.7	1.9	1.5	1.5	3.1	3.3	2.1	2.6	2.0	1.6
Sitting height	2.2	15.8	81.2	0.4	6.0	5.0	-0.5	9.0	3.3	6.7	2.5	-0.7	-1.2	3.5	6.5	2.4	3.9	0.5	-1.5
Pulse wave peak to peak time	2.2	2.6	4.2	2.0	0.1	1.9	2.1	1.7	1.8	1.4	1.5	2.0	1.8	1.8	1.5	1.6	1.7	1.6	1.8
Basal metabolic rate	2.2	12.0	40.7	-3.1	0.6	-1.4	-3.3	-2.0	-4.0	-2.9	-2.4	-3.3	-3.9	-5.2	-2.1	-6.4	-4.3	-4.5	-4.7
Heart attack/myocardial infarction (self-reported)	2.2	2.9	6.8	-2.2	0.2	-2.1	-2.0	-2.6	-2.2	-0.9	-1.2	-1.8	-1.7	-1.8	-1.8	-1.4	-1.7	-2.2	-1.6
Waist Hip Ratio (WHR)	2.1	9.6	27.2	3.1	3.7	1.1	3.2	1.3	3.6	3.6	5.2	4.2	3.3	2.7	3.5	0.6	3.8	3.2	3.5
Supplements: Glucosamine	2.1	2.7	5.4	-2.3	-0.7	-2.1	-2.2	-1.5	-1.6	-1.4	-1.2	-2.2	-1.9	-2.0	-1.0	-1.8	-1.6	-1.6	-1.9
Heart attack	2.1	2.7	7.6	-2.1	0.4	-2.2	-1.9	-2.8	-2.1	-0.8	-1.0	-1.6	-1.6	-1.7	-1.7	-1.2	-1.6	-2.0	-1.4
Medication: Lansoprazole	2.1	2.4	6.3	1.6	2.5	-0.3	1.9	-0.9	1.5	1.7	2.0	2.5	2.2	1.2	1.1	0.9	1.4	0.6	2.0
Loneliness, isolation	2.1	3.0	7.5	-2.3	-2.7	-1.9	-1.7	-2.5	-1.7	-1.3	-1.8	-1.5	-1.6	-1.4	-1.6	-1.6	-1.8	-1.4	-1.7
Arm predicted mass (left)	2.1	10.5	35.2	-3.1	0.9	-1.4	-3.4	-1.5	-3.6	-2.2	-2.1	-3.4	-4.0	-4.8	-1.8	-5.9	-3.8	-4.2	-4.6
Triglycerides	2.0	3.3	7.4	2.5	0.7	0.9	2.5	0.9	2.1	1.6	1.9	2.7	2.6	2.1	1.4	1.1	1.8	1.8	2.5
Leg fat-free mass (left)	2.0	10.5	34.6	-2.9	0.0	-1.6	-2.9	-2.6	-3.7	-2.9	-2.5	-2.8	-3.4	-4.8	-2.2	-5.9	-4.1	-4.3	-4.1
Leg predicted mass (left)	2.0	10.5	34.3	-3.0	0.1	-1.7	-2.9	-2.7	-3.7	-2.8	-2.5	-2.9	-3.3	-4.8	-2.2	-5.9	-4.1	-4.4	-4.1
Ever used hormone-replacement therapy (HRT)	1.9	2.4	6.6	1.1	2.6	0.7	0.8	1.5	1.6	2.4	2.5	1.0	0.9	1.8	2.1	1.5	2.0	1.2	1.2
Had other major operations	1.9	2.4	10.4	-0.9	1.6	-1.0	-0.9	-2.4	-1.7	-0.6	-1.1	-1.4	-0.9	-1.8	-2.1	-1.7	-1.4	-3.2	-1.1
Pulse wave Arterial Stiffness index	1.9	2.2	4.6	-1.9	0.4	-1.4	-2.1	-1.0	-1.6	-1.1	-1.1	-2.1	-2.0	-1.6	-0.9	-1.7	-1.5	-1.5	-2.0
Arm predicted mass (right)	1.9	9.8	29.5	-3.2	0.9	-1.5	-3.4	-1.6	-3.4	-2.1	-2.1	-3.4	-3.8	-4.5	-1.6	-5.4	-3.5	-4.2	-4.4
Miserableness	1.9	3.2	5.8	-2.0	-1.4	-1.4	-1.6	-1.8	-2.0	-2.1	-2.3	-1.8	-1.7	-2.0	-2.4	-1.8	-2.4	-1.6	-1.9
Commuting to job workplace: Cycle	1.9	2.3	6.7	2.6	1.3	2.3	2.3	1.4	1.0	0.1	1.3	1.3	1.6	1.0	0.3	2.1	1.2	1.4	1.9
Schizophrenia vs Biploar Disorder	1.8	2.4	5.8	1.0	-0.9	-0.4	1.2	0.8	2.1	2.1	0.9	1.3	1.6	2.3	1.8	2.4	2.2	1.6	1.6
Neuroticism (2016)	1.8	2.5	5.6	1.4	0.6	1.9	1.4	2.2	2.1	1.6	1.5	1.4	1.2	2.4	1.7	1.6	1.9	2.1	1.0
Tinnitus: Yes, but not now, but have in the past	1.8	1.9	4.0	-1.7	-0.9	-2.0	-1.2	-1.6	-1.5	-1.3	-1.9	-0.7	-0.7	-1.5	-1.8	-1.4	-1.6	-1.7	-1.2
Medication: Atenolol	1.8	2.2	7.3	-0.8	-0.0	-0.1	-1.0	-1.7	-2.0	-2.7	-1.2	-1.4	-1.3	-2.1	-2.6	-1.5	-1.9	-0.9	-1.0
Medication: Blood pressure	1.8	3.1	6.5	-2.0	1.4	-1.4	-1.9	-1.0	-2.1	-0.7	-1.8	-1.7	-1.7	-2.5	-2.2	-2.3	-2.0	-2.5	-1.6
Alcohol drinker status: Previous	1.8	2.0	5.9	-1.5	-0.2	-1.4	-1.4	-1.5	-1.6	-2.4	-1.6	-1.2	-1.0	-1.9	-1.8	-1.1	-1.7	-1.1	-1.4
HbA1C	1.7	1.9	6.5	-1.9	-1.1	-2.4	-1.8	-2.5	-1.4	-1.5	-0.4	-1.0	-1.4	-1.4	-0.4	-0.9	-1.5	0.0	-1.3
Chronotype (morning person)	1.7	3.8	7.3	1.1	2.7	0.2	1.3	2.6	2.7	2.6	2.2	1.6	1.7	2.2	2.5	1.9	2.6	1.9	1.7
Tanning	1.7	20.6	50.6	4.0	4.8	4.2	3.7	5.3	5.4	7.1	6.0	3.8	3.2	4.5	6.8	2.7	5.6	3.7	3.3
Worry too long after embarrassment	1.7	2.9	6.1	2.3	0.3	1.6	2.5	0.8	1.6	0.6	1.9	2.3	1.9	1.8	2.2	1.6	1.3	2.3	2.0
Whole body fat-free mass	1.7	9.5	33.3	-3.0	1.0	-1.1	-3.2	-1.2	-3.3	-1.9	-1.9	-3.1	-3.8	-4.5	-1.3	-5.8	-3.5	-4.2	-4.5
Leg fat-free mass (right)	1.7	9.1	30.9	-2.8	0.0	-1.5	-2.7	-2.4	-3.4	-2.3	-2.3	-2.8	-3.2	-4.4	-1.8	-5.6	-3.7	-4.2	-3.9
Whole body water mass	1.7	9.5	33.3	-3.0	1.0	-1.1	-3.2	-1.2	-3.3	-2.0	-1.9	-3.1	-3.8	-4.5	-1.3	-5.8	-3.5	-4.1	-4.5
Leg predicted mass (right)	1.7	9.1	30.9	-2.8	0.0	-1.5	-2.8	-2.4	-3.4	-2.3	-2.3	-2.8	-3.2	-4.4	-1.7	-5.6	-3.7	-4.1	-4.0
Time employed in main current job	1.6	1.9	14.0	1.3	1.7	3.7	0.7	2.6	0.9	1.0	1.4	0.2	0.0	0.7	1.4	-0.0	1.2	0.6	0.1
Arm fat-free mass (right)	1.6	8.2	26.3	-2.9	1.0	-1.3	-3.1	-1.4	-3.1	-1.8	-1.8	-3.1	-3.5	-4.2	-1.4	-5.1	-3.1	-4.0	-4.1
Eye problems/disorders: None of the above	1.6	1.8	6.4	0.7	-0.1	0.4	0.8	1.7	1.9	2.3	1.3	0.7	0.9	1.6	2.5	1.2	1.8	1.2	1.0
Average weekly red wine intake	1.6	2.4	5.2	-1.7	1.6	-0.3	-2.0	-0.4	-2.0	-2.2	-0.6	-1.8	-2.3	-2.1	-0.9	-1.3	-1.8	-0.7	-2.2
Ever had bowel cancer screening	1.6	1.8	3.5	1.3	1.3	1.8	0.9	1.4	1.4	1.5	1.7	0.9	0.9	1.9	1.8	1.6	1.6	1.2	1.1
Schizophrenia (2018)	1.5	3.2	13.2	0.9	2.3	-0.9	0.9	0.2	2.1	3.6	1.8	0.8	1.4	2.4	2.4	2.4	2.5	0.2	1.7
Schizophrenia (2014)	1.5	3.2	11.2	0.9	2.3	-1.3	1.0	-0.2	2.2	3.4	2.0	1.2	1.8	2.2	2.2	2.1	2.7	0.4	1.9
Smoking Status	1.5	3.5	8.8	-2.0	-0.6	-3.0	-1.8	-2.9	-1.6	-0.9	-2.0	-1.7	-1.2	-2.3	-2.1	-1.9	-1.6	-2.9	-1.5
Trunk fat-free mass	1.5	8.5	30.7	-2.8	1.7	-0.5	-3.2	-0.1	-3.0	-1.4	-1.4	-3.0	-3.9	-4.2	-0.7	-5.5	-3.0	-3.8	-4.7
Trunk predicted mass	1.5	8.8	31.5	-2.9	1.7	-0.6	-3.3	-0.2	-3.0	-1.5	-1.5	-3.1	-4.0	-4.2	-0.8	-5.6	-3.1	-3.8	-4.7
Tense / ‘highly strung’	1.5	2.5	13.2	1.1	0.7	1.5	0.7	3.6	1.5	2.4	1.7	0.8	0.5	1.8	2.2	1.2	1.5	1.7	0.8
Wheeze or whistling in the chest in last year	1.5	2.6	9.2	-1.9	0.1	-3.0	-1.7	-1.9	-1.4	0.4	-1.0	-1.4	-1.2	-1.9	-1.1	-2.4	-1.6	-2.5	-1.3
Qualifications: College or University degree	1.5	4.7	9.9	2.6	-1.2	2.2	2.1	2.9	2.4	1.3	2.7	2.3	1.5	2.5	3.1	1.5	2.3	3.1	1.7
Smoking status: Previous	1.5	2.3	4.7	-1.5	0.2	-2.2	-1.3	-1.7	-1.8	-2.1	-1.5	-1.2	-1.0	-2.0	-1.9	-1.2	-1.7	-2.0	-1.0
Angina	1.4	1.8	4.1	-0.7	0.9	-1.0	-0.6	-2.0	-1.9	-1.4	-1.2	-0.7	-0.6	-2.0	-1.9	-1.6	-2.0	-1.9	-0.7
Forced vital capacity (FVC)	1.4	5.4	24.6	0.6	4.3	2.9	-0.4	5.0	1.6	0.8	3.3	0.0	-1.3	1.3	3.9	0.6	2.3	2.2	-1.3
Illnesses of mother	1.4	1.7	7.2	1.0	0.9	0.3	1.2	0.5	1.4	0.6	1.4	1.5	1.3	1.7	1.4	2.7	1.5	1.9	1.2
Health satisfaction	1.4	1.8	4.0	1.1	2.0	-0.1	1.5	0.5	1.6	1.6	1.8	1.8	1.8	1.3	1.3	1.1	1.7	0.6	1.6
Medication: Bendroflumethiazide	1.4	2.2	6.8	-1.5	-1.6	-1.0	-1.7	0.1	-1.4	-2.0	-1.4	-1.1	-1.5	-2.0	-1.6	-2.6	-1.8	-0.4	-1.6
Myopia	1.4	2.1	10.0	0.3	0.8	-0.5	0.5	1.2	1.6	3.2	1.9	0.9	0.6	1.8	2.7	1.0	1.8	1.1	1.1
Ever had hysterectomy (womb removed)	1.3	1.5	3.8	-1.7	-0.0	-0.7	-1.9	-0.3	-1.4	-1.0	-0.8	-1.9	-1.8	-1.4	-1.0	-1.3	-1.0	-1.1	-1.4
Current tobacco smoking	1.3	2.1	4.5	-1.8	-0.8	-2.0	-1.7	-1.9	-1.1	-0.4	-1.4	-1.5	-1.2	-1.6	-1.4	-1.9	-1.3	-2.1	-1.5
Taking other prescription medications	1.3	2.0	5.9	1.8	1.4	-0.3	2.0	-0.8	1.4	1.9	1.4	2.0	2.4	0.9	0.5	0.2	1.3	-0.1	2.3
Medication: Ibuprofen (e.g. Nurofen)	1.3	1.7	4.0	-1.8	-0.3	-2.0	-1.6	-0.6	-1.2	-0.8	-0.8	-1.6	-1.8	-1.6	-1.0	-1.7	-1.1	-1.2	-1.6
Medication for pain relief, constipation, heartburn	1.3	2.2	5.4	1.2	-0.6	1.4	1.4	1.9	1.8	0.4	0.8	1.5	1.5	2.0	1.4	2.3	1.6	2.2	1.5
Angina (self-reported)	1.3	1.8	4.1	-0.5	1.0	-0.9	-0.5	-2.0	-1.9	-1.4	-1.2	-0.5	-0.5	-2.0	-1.9	-1.6	-2.0	-2.0	-0.7
Qualifications: NVQ or HND or HNC or equivalent	1.3	1.5	3.7	1.1	0.4	0.4	1.5	0.5	1.2	1.7	1.1	1.5	1.8	1.6	0.9	1.6	1.2	1.1	1.9
Medication: Aspirin	1.3	1.8	3.8	-1.4	0.3	-0.4	-1.6	-1.1	-1.8	0.0	-1.1	-1.4	-1.5	-1.6	-1.2	-1.9	-1.7	-2.0	-1.5
Guilty feelings	1.3	1.9	3.6	-1.5	-0.9	-0.9	-1.6	-1.9	-1.8	-1.0	-0.9	-1.7	-1.7	-1.5	-0.6	-1.6	-1.7	-1.6	-1.7
Eye problems/disorders: Diabetes related eye disease	1.2	1.3	3.0	-1.3	-0.2	-1.0	-1.2	-1.3	-1.7	-0.9	-1.2	-1.4	-0.9	-1.0	-1.6	-0.8	-1.4	-1.7	-0.7
Birth weight of first child	1.2	2.1	5.9	1.0	2.1	1.0	0.9	2.0	1.8	2.3	1.5	0.8	1.0	1.6	2.4	1.1	1.9	0.8	1.0
Loud music exposure frequency	1.2	1.3	3.7	0.4	-0.2	-0.6	0.5	0.9	1.7	0.7	1.1	0.8	0.9	1.9	1.4	1.8	1.9	1.6	1.2
Glaucoma (self-reported)	1.2	1.4	3.9	-0.9	-1.4	-0.6	-0.8	-0.7	-1.2	-2.0	-1.9	-1.0	-0.8	-1.4	-1.9	-0.6	-1.3	-1.0	-1.1
Medication: Ibuprofen	1.2	1.4	3.5	-1.6	-0.1	-1.9	-1.6	-0.9	-1.1	-0.3	-0.5	-1.6	-1.6	-1.3	-0.7	-1.6	-0.9	-1.5	-1.4
Alcohol intake frequency.	1.2	2.9	5.9	-2.1	-1.1	-1.5	-1.9	-1.7	-1.9	-2.4	-1.9	-1.8	-1.4	-2.0	-1.8	-1.9	-2.0	-1.7	-1.5
Knee pain experienced in last month	1.2	1.8	4.9	-1.1	0.2	-1.4	-1.0	-1.3	-1.5	-1.1	-0.9	-1.2	-1.3	-2.0	-1.1	-2.1	-1.4	-2.2	-1.7
Handedness (chirality/laterality): Left-handed	1.2	1.4	3.0	0.9	0.6	0.1	1.4	1.5	1.5	0.6	0.8	1.7	1.6	1.4	1.1	1.6	1.2	1.6	1.3
Illnesses of father: High blood pressure	1.2	1.5	4.3	-1.4	-1.2	-0.6	-1.8	0.9	-0.9	-0.8	-0.9	-2.1	-2.0	-1.2	-0.4	-1.8	-0.9	-0.5	-1.6
Crohns Disease (2017)	1.1	2.3	10.0	0.6	-1.1	-0.7	0.7	-3.2	-1.3	-2.6	-0.8	0.7	0.6	-2.1	-2.6	-2.3	-1.6	-1.0	0.2
Hayfever, allergic rhinitis or eczema	1.1	2.3	6.3	1.8	-0.5	0.6	1.5	1.4	1.9	2.1	1.8	1.1	1.1	1.8	2.5	1.6	2.2	1.3	1.1
Peak expiratory flow (PEF)	1.1	2.5	12.2	1.6	3.5	2.6	1.3	2.3	1.4	0.6	2.1	0.8	0.4	1.0	2.0	1.0	1.6	1.1	0.4
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.3	4.9	0.8	1.1	1.7	0.7	2.2	1.2	1.7	0.8	0.6	0.7	1.4	1.5	1.1	1.1	0.7	0.8
Family relationship satisfaction	1.1	1.3	5.2	1.0	1.2	1.0	1.0	1.8	1.4	2.3	1.1	0.9	0.9	1.3	1.2	0.5	1.5	0.3	0.7
Medication: Aspirin	1.1	1.5	4.1	-1.1	0.5	0.1	-1.3	-1.0	-1.6	0.1	-1.0	-1.2	-1.3	-1.6	-1.0	-2.0	-1.6	-1.9	-1.4
Bipolar Disorder or Schizophrenia	1.0	2.5	10.0	1.1	3.2	-1.0	1.0	0.3	1.7	2.5	2.1	1.1	1.5	1.5	1.9	1.5	2.0	0.7	1.7
Fasting Glucose	1.0	1.2	3.0	1.2	-0.5	1.3	1.2	1.5	1.3	1.6	0.4	1.0	1.1	1.7	0.9	1.1	1.0	0.8	0.9
Medication for hormone replacement therapy	1.0	1.1	3.2	0.6	1.4	-0.9	0.7	-0.4	1.0	1.7	1.2	0.7	1.0	1.3	0.7	1.8	1.6	0.2	1.1
Pack years adult smoking proportion	1.0	1.6	5.0	-1.2	0.1	-2.2	-1.0	-2.2	-1.4	-0.4	-0.9	-1.1	-0.6	-1.7	-0.9	-1.4	-1.4	-1.9	-0.6
Allergy	1.0	2.4	5.2	-1.9	0.7	-1.1	-1.7	-1.8	-1.9	-2.2	-1.5	-1.1	-1.3	-1.8	-2.3	-1.4	-2.0	-1.2	-1.2
Forced vital capacity (FVC), Best measure	1.0	3.6	18.4	0.3	3.9	2.6	-0.5	4.3	1.0	0.2	2.3	-0.3	-1.4	0.4	2.9	-0.3	1.4	1.4	-1.6
Exposure to tobacco smoke outside home	1.0	1.4	4.0	-0.8	0.5	-0.1	-0.6	-1.3	-1.7	-1.5	-1.6	-0.9	-0.7	-1.6	-2.0	-1.0	-1.8	-1.3	-0.8
Age at first live birth	1.0	1.7	7.3	1.2	1.0	1.7	0.9	2.7	1.4	1.5	1.1	0.7	0.4	1.5	1.8	1.5	1.4	1.3	0.3
Smoking status: Current	1.0	1.7	4.0	-1.6	-0.7	-1.7	-1.5	-1.7	-0.9	-0.0	-1.2	-1.3	-1.0	-1.4	-1.1	-1.9	-1.1	-2.0	-1.4
Ever taken oral contraceptive pill	1.0	1.1	3.5	-1.8	-0.4	-1.8	-1.9	-0.2	-0.8	-0.4	-0.4	-1.3	-1.7	-0.6	0.4	-0.7	-0.5	-0.5	-1.6
Medication: Lisinopril	1.0	1.2	5.5	-0.7	0.7	0.2	-0.4	0.0	-1.2	-1.2	-1.2	-0.2	-0.5	-1.7	-1.8	-2.3	-1.4	-1.3	-1.0
Alzheimer’s Disease (in father)	0.9	1.0	4.6	0.3	-0.7	-0.1	0.6	0.7	1.3	0.4	-0.1	0.6	1.2	1.7	0.5	2.1	1.2	1.3	1.2
Hand grip strength (left)	0.9	2.3	9.9	-1.6	1.3	0.5	-2.3	2.5	-0.4	-0.2	0.2	-1.9	-2.8	-0.5	1.4	-1.0	0.2	-0.5	-3.1
Other serious medical condition/disability diagnosed by doctor	0.9	1.2	5.3	-0.1	1.6	-2.3	0.5	-1.7	0.9	1.3	1.4	1.3	1.3	0.6	0.5	0.2	0.9	-0.2	1.1
Severe depression (siblings)	0.9	1.0	5.0	-1.3	-1.2	-2.2	-1.0	-1.8	-0.5	1.0	-0.4	-0.8	-0.5	-0.4	-0.1	-1.1	-0.7	-0.8	-0.1
Hand grip strength (right)	0.9	2.6	9.6	-1.4	2.1	0.9	-2.1	2.5	-0.7	0.1	0.2	-2.2	-2.9	-0.7	1.6	-1.1	-0.1	-0.9	-3.1
Townsend deprivation index at recruitment	0.9	1.3	3.0	-1.7	0.7	-1.6	-1.4	-1.6	-1.2	-0.7	-0.5	-1.2	-1.1	-1.0	-1.4	-1.2	-0.9	-1.2	-0.8
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	2.1	1.4	0.9	1.1	1.4	0.6	1.0	1.2	1.1	0.9	1.3	1.0	0.4	1.4	1.3	0.7	1.5
Medication: Levothyroxine sodium	0.9	1.5	4.2	1.4	-0.5	-0.4	1.5	0.1	1.4	0.8	1.4	1.6	1.8	1.4	1.1	0.9	1.5	1.3	2.0
Hearing difficulty/problems with background noise	0.9	1.4	5.3	0.7	-0.3	-1.8	0.8	-0.4	1.3	2.3	1.4	1.1	1.1	1.4	1.5	0.6	1.4	0.8	1.3
Hair/balding pattern: Pattern 2	0.9	1.2	4.3	-1.1	0.2	-1.6	-0.8	-2.1	-1.4	-1.1	-0.4	-0.6	-0.6	-1.5	-1.4	-1.3	-1.4	-1.0	-0.5
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.0	4.4	-2.0	-0.8	-1.6	-2.1	-1.1	-1.8	-0.3	-1.7	-1.9	-1.7	-1.0	-1.6	-0.4	-1.5	-1.8	-1.4
Ever unenthusiastic/disinterested for a whole week	0.9	1.0	3.7	-1.9	0.7	-1.9	-1.7	-1.6	-0.9	-1.1	-0.1	-1.0	-0.9	-0.5	-0.2	-0.5	-0.6	-0.4	-0.7
Forced expiratory volume in 1-second (FEV1)	0.9	3.2	14.1	1.3	3.8	2.8	0.6	3.2	1.2	-0.2	2.6	0.6	-0.3	0.9	2.3	0.8	1.7	2.0	-0.2
Breastfed as a baby	0.9	1.1	9.4	-0.1	0.3	2.1	-0.6	3.1	-0.4	0.3	-0.1	-1.0	-1.4	-0.4	0.4	-0.8	-0.1	0.0	-1.1
Heart disease (mother)	0.9	1.0	5.7	-0.1	0.4	0.3	-0.3	-0.2	-1.1	-1.5	-0.6	-0.3	-0.4	-1.8	-1.7	-2.4	-1.2	-0.9	-0.6
Age at last live birth	0.9	1.4	8.2	0.1	0.4	0.6	0.1	2.9	1.4	1.4	1.0	0.3	-0.0	1.4	1.9	1.2	1.4	1.5	0.1
Eye problems/disorders: Glaucoma	0.9	1.1	2.3	-0.9	-1.0	-0.2	-0.9	-0.3	-1.3	-1.5	-1.4	-1.2	-1.0	-1.2	-1.5	-0.9	-1.4	-0.9	-1.2
Vascular/heart problems diagnosed by doctor	0.9	2.6	9.6	1.5	-0.8	1.4	1.3	1.4	1.9	1.5	1.0	0.7	1.0	2.5	2.3	3.1	2.1	1.7	1.0
Medication: Omeprazole (e.g. Zanprol)	0.9	1.1	3.4	1.8	1.5	1.8	1.5	0.5	0.8	0.9	0.7	1.3	1.3	0.9	-0.2	0.4	0.9	0.2	1.4
Pain experienced in last month	0.9	1.6	4.5	1.6	-0.2	0.5	1.7	0.6	1.3	0.3	1.0	1.8	1.9	1.2	0.4	1.5	1.3	1.5	2.1
Pack years of smoking	0.9	1.3	4.6	-0.9	0.3	-1.7	-0.7	-2.1	-1.3	-0.3	-0.8	-0.9	-0.4	-1.5	-0.9	-1.3	-1.4	-1.8	-0.4
Irritable Bowel Disease (IBD)	0.8	1.8	12.3	1.0	-0.7	-0.7	1.1	-3.5	-0.5	-1.6	-0.3	1.0	1.2	-1.5	-2.2	-1.8	-0.9	-1.0	0.8
Age at First Birth	0.8	1.2	3.3	0.7	1.3	0.4	0.9	1.7	1.1	1.5	0.8	0.7	0.9	1.3	1.1	1.8	1.1	1.0	1.1
Heel T-Score	0.8	6.7	18.0	-3.6	-2.6	-2.1	-3.4	-1.8	-3.0	-0.7	-4.2	-3.8	-2.9	-1.2	-2.9	0.6	-2.6	-3.0	-2.4
Type 2 Diabetes (T2D) (2018)	0.8	1.4	4.4	1.6	0.8	0.4	1.6	0.1	0.7	2.1	1.2	1.5	1.7	1.3	0.7	0.7	0.8	0.3	2.1
Happiness	0.8	1.0	5.1	-1.5	0.2	-2.3	-1.1	-1.2	-0.3	1.5	-0.1	-0.9	-0.6	-0.4	0.1	-1.4	-0.3	-1.3	-0.7
Suffer from ‘nerves’	0.8	1.2	5.5	0.1	0.2	1.0	0.2	1.8	1.2	2.2	1.2	0.6	0.3	1.4	2.4	0.3	0.9	0.8	0.2
Commuting to job workplace: Walk	0.8	0.9	2.2	0.6	0.1	0.2	0.6	-0.0	1.3	0.7	0.7	0.8	1.1	1.5	1.3	1.5	1.1	1.3	1.2
Mineral and other dietary supplements	0.8	1.1	2.8	1.6	0.1	1.1	1.7	0.5	0.9	0.4	0.8	1.5	1.4	1.2	0.3	1.1	0.9	1.0	1.3
Risk taking	0.8	1.2	3.6	-0.9	1.3	0.1	-1.1	-1.2	-1.5	-0.6	-1.1	-1.4	-1.1	-1.2	-1.4	-0.4	-1.2	-1.9	-1.2
Ever had prostate specific antigen (PSA) test	0.8	1.0	3.1	0.6	0.8	0.8	0.7	0.9	1.3	1.8	0.9	0.8	0.8	1.3	1.2	1.3	1.3	0.4	0.9
Blood White Count	0.7	5.2	14.8	-1.6	-1.8	-2.4	-1.3	-3.7	-2.4	-3.1	-1.1	-1.0	-1.3	-3.3	-3.3	-3.9	-2.5	-1.5	-1.2
Number of treatments/medications taken	0.7	1.2	7.1	-0.8	1.1	-2.7	-0.5	-2.3	-0.8	0.3	0.3	-0.4	0.1	-1.0	-0.9	-1.3	-0.4	-1.6	0.3
Systolic blood pressure, automated reading	0.7	1.9	4.4	1.2	1.9	0.6	1.1	2.1	1.7	1.2	1.8	1.7	1.3	1.1	1.3	0.5	1.5	2.0	1.3
Vitamin and mineral supplements	0.7	0.9	2.8	1.7	0.0	1.6	1.5	0.0	0.5	-0.6	0.8	1.5	1.2	0.4	-0.0	0.3	0.2	1.5	1.1
Qualifications: None of the above	0.7	1.4	4.6	-1.2	0.2	-0.6	-1.3	-1.7	-1.3	-0.6	-1.0	-1.5	-1.2	-1.2	-1.3	-1.2	-0.9	-2.1	-1.4
Father’s age at death	0.7	0.9	4.7	-1.2	-2.2	-0.3	-1.4	0.8	-0.4	-0.1	-0.8	-1.0	-1.4	-0.6	-0.1	-1.1	-0.3	-0.6	-1.5
Noisy workplace	0.7	0.9	4.0	0.1	-0.0	-1.2	0.4	-0.3	1.1	2.0	0.7	0.8	1.0	1.4	1.7	1.0	0.9	0.3	0.9
Depression (self-reported)	0.7	0.8	4.0	-1.3	-1.5	-1.3	-1.1	-2.0	-0.7	-0.2	-0.9	-0.8	-0.5	-0.1	-1.0	-0.4	-0.5	-0.5	-0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.1	12.9	1.0	3.6	2.5	0.4	2.8	0.6	-0.7	1.9	0.4	-0.5	0.1	1.6	0.0	0.9	1.2	-0.7
Emphysema/chronic bronchitis	0.7	0.8	3.8	0.5	0.7	-1.0	0.5	0.7	1.2	1.9	0.9	1.0	0.9	0.8	1.1	0.6	1.1	0.6	0.6
Medication: Omeprazole	0.7	0.8	4.2	1.3	2.0	1.9	1.0	0.9	0.3	0.4	0.7	0.8	0.8	0.3	-0.3	-0.0	0.5	-0.1	0.8
Friendships satisfaction	0.7	0.9	4.9	0.5	0.8	0.1	0.8	0.9	1.5	2.2	0.5	0.9	0.8	1.2	1.2	0.4	1.2	0.2	0.4
Qualifications: nursing, teaching	0.7	1.0	3.3	1.8	0.4	1.4	1.5	0.1	0.8	0.0	1.2	1.2	1.2	1.1	0.7	1.1	0.9	1.0	1.2
Osteoporosis (self-reported)	0.7	0.9	3.7	0.4	0.7	0.8	0.2	-0.8	-0.9	-1.3	-0.6	-0.4	-0.4	-1.6	-1.3	-1.9	-1.2	-1.2	-0.9
Hearing aid user	0.7	0.8	5.1	0.4	-1.0	-1.5	0.8	-2.3	-0.1	0.0	-0.4	0.7	1.1	-0.4	-1.2	0.1	-0.5	-0.5	0.9
Medication: Atorvastatin	0.7	0.8	3.7	-0.7	-0.6	-1.9	-0.3	-1.9	-0.3	-1.1	-1.0	0.0	0.1	-0.8	-1.3	-0.2	-0.3	-1.1	-0.4
Ever depressed for a whole week	0.7	0.9	2.6	-1.6	0.4	-0.7	-1.5	-1.0	-1.1	-0.5	-0.6	-1.3	-1.2	-0.8	-0.5	-0.7	-0.9	-1.1	-1.2
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	8.1	1.3	0.3	2.9	1.0	1.5	0.3	0.2	0.6	0.6	0.4	0.5	0.5	0.3	0.4	0.6	0.5
Verbal and Numeric Reasoning (VNR)	0.6	1.4	8.0	0.5	-2.1	1.2	0.6	0.9	-0.8	-2.8	-1.2	0.3	0.0	-1.0	-1.6	-0.7	-1.5	0.7	-0.1
HDL Cholesterol	0.6	1.1	3.5	-1.1	-0.7	0.5	-1.4	1.0	-1.0	-0.4	-1.2	-1.7	-1.9	-0.6	-0.6	-0.5	-0.6	-0.9	-1.7
Primary Biliary Cirrhosis	0.6	0.9	2.6	0.9	0.3	-0.1	1.2	-1.0	-0.2	-1.6	0.2	1.3	1.3	-0.4	-1.4	0.7	-0.4	1.1	1.6
Allergy or Eczema	0.6	1.5	5.7	1.5	-0.5	0.3	1.0	1.6	1.5	1.9	1.4	0.8	0.6	1.2	2.4	0.8	1.6	1.0	0.4
Lung FEV1/FVC ratio	0.6	3.3	15.1	0.8	-0.3	-0.9	1.5	-3.9	-1.5	-2.7	-1.2	1.4	1.7	-1.9	-3.6	-0.5	-2.0	-0.7	1.8
Lung FVC	0.6	3.1	9.2	-1.7	-0.3	-0.1	-2.5	0.6	-1.9	-3.0	-1.1	-2.7	-3.0	-1.7	-1.7	-1.3	-1.4	-0.4	-2.6
Supplements: Zinc	0.6	0.6	2.3	-1.5	1.0	-0.9	-1.4	-0.7	-0.9	-0.4	0.1	-1.3	-1.2	-0.2	0.3	0.3	-0.4	-0.4	-0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	0.6	0.8	1.7	-1.1	-1.1	0.0	-1.0	-0.5	-1.3	-0.6	-0.9	-1.3	-1.3	-0.6	-1.1	-1.0	-1.2	-0.6	-1.0
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	3.5	-0.3	1.9	0.4	-0.6	0.4	-0.8	0.3	0.1	-0.6	-1.0	-1.1	-0.4	-1.3	-0.7	-1.1	-1.2
Qualifications: CSEs or equivalent	0.6	0.8	5.1	0.9	2.2	0.3	1.0	-0.1	0.3	1.6	0.9	0.7	1.0	0.4	0.2	0.7	0.3	-0.3	1.1
Serious illness, injury or assault to yourself	0.6	0.7	4.9	0.7	2.2	-0.4	0.8	-1.1	0.2	0.9	0.9	1.0	1.0	0.2	0.5	0.5	0.2	-0.4	0.7
Chronic bronchitis/emphysema (father)	0.6	0.7	4.6	0.1	0.7	2.1	-0.3	0.9	-0.7	-0.7	-0.9	-0.9	-0.9	-0.5	-0.7	-0.2	-0.7	-0.5	-1.1
Pain all over the body in last month	0.6	0.6	2.5	-1.3	-0.6	-1.6	-1.4	-1.2	-0.2	-0.5	-0.3	-0.8	-0.9	-0.3	-0.2	-0.3	-0.1	-0.1	-0.9
Mouth/teeth dental problems: Bleeding gums	0.6	0.7	2.0	1.2	1.2	0.6	1.3	-0.8	0.6	0.5	0.8	1.4	1.3	0.7	-0.1	0.7	0.5	0.5	1.1
Headache pain in last month	0.6	1.0	3.2	0.9	-0.3	0.4	0.9	0.3	1.6	1.3	1.4	0.9	0.8	1.3	1.8	0.4	1.3	1.2	0.8
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	3.1	1.0	-0.9	1.8	0.9	1.4	0.9	-0.1	1.1	0.6	0.4	1.3	1.5	1.0	0.9	1.4	0.4
Migraine (self-reported)	0.6	0.7	2.7	-0.7	-1.3	-0.0	-0.8	-0.5	-0.9	-0.4	-1.0	-0.7	-0.8	-1.1	-0.8	-1.6	-1.1	-0.7	-0.6
Hypertension (Self-reported)	0.6	1.8	8.6	-0.9	1.7	-0.8	-0.8	-0.6	-1.5	-1.1	-0.5	-0.2	-0.6	-2.4	-1.9	-2.9	-1.7	-1.3	-0.7
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	2.0	-1.1	-0.4	-1.3	-1.2	-1.4	-0.2	0.7	-0.4	-1.4	-1.1	0.1	0.1	0.4	0.3	-0.6	-1.0
Illnesses of father: None of the above (group 1)	0.6	0.7	1.3	1.0	0.6	0.5	0.9	-0.6	0.9	1.0	1.1	1.0	0.9	0.9	1.1	0.9	0.9	0.6	0.8
Supplements: Calcium	0.6	0.7	4.9	1.1	0.7	1.5	0.3	2.2	0.0	0.4	1.0	-0.2	-0.2	0.5	0.8	0.6	0.3	0.8	0.1
Major Depression (MDD)	0.5	0.6	1.5	0.1	0.6	1.1	0.1	-0.7	-0.8	-1.2	-0.8	-0.1	0.0	-1.0	-1.2	-0.9	-1.0	-1.0	-0.3
Crohns Disease (2012)	0.5	0.9	3.0	1.7	-1.4	0.4	1.6	-1.1	0.3	-0.9	0.1	1.4	1.3	-0.5	-0.7	-0.9	-0.1	0.4	0.9
Systolic Blood Pressure	0.5	2.5	10.2	0.9	1.7	1.6	0.6	3.2	2.0	1.5	1.9	1.4	0.7	1.5	1.8	0.0	2.1	2.4	0.7
Average weekly spirits intake	0.5	0.6	3.6	1.2	1.9	1.4	0.9	0.4	-0.0	-0.0	-0.2	0.1	0.5	-0.8	-0.5	-0.8	-0.2	-0.7	0.3
Frequency of depressed mood in last 2 weeks	0.5	0.7	2.3	-0.8	-1.3	-0.4	-0.7	-0.5	-0.7	-1.0	-0.9	-0.3	-0.7	-0.8	-0.8	-1.5	-1.0	-0.5	-1.1
Diabetes (father)	0.5	0.6	3.6	0.4	-1.8	0.8	0.3	1.1	-0.0	1.9	-0.8	-0.4	-0.1	0.5	0.0	-0.4	-0.1	-0.8	0.1
Average weekly fortified wine intake	0.5	0.5	2.2	1.5	-0.3	1.4	1.2	1.0	0.5	0.2	0.7	0.8	0.6	0.5	0.6	0.4	0.5	0.7	0.4
Heel bone mineral density (BMD) T-score, automated (left)	0.5	1.2	4.3	-1.6	-0.4	-2.1	-1.4	-1.3	-1.1	0.5	-1.2	-1.3	-0.9	-0.1	-1.2	0.8	-0.6	-1.7	-0.6
High blood pressure	0.5	1.4	7.5	-0.7	1.4	-0.6	-0.6	-0.4	-1.2	-1.2	-0.5	-0.1	-0.4	-2.1	-1.9	-2.7	-1.5	-1.0	-0.5
Number of incorrect matches in round	0.5	0.8	3.1	-0.8	-0.9	0.3	-1.1	1.8	0.4	1.2	0.4	-0.6	-1.0	0.7	1.8	-0.1	0.6	0.6	-0.8
Had menopause	0.5	0.7	1.3	0.8	1.1	0.6	0.6	1.0	1.0	0.5	1.1	0.7	0.7	1.0	0.6	0.9	1.1	0.9	0.8
Fluid intelligence score	0.5	1.1	4.8	1.6	-0.2	2.2	1.8	0.9	0.2	-1.4	-0.2	1.2	1.1	0.1	-0.8	0.6	-0.1	1.0	1.0
Frequency of tiredness / lethargy in last 2 weeks	0.5	0.7	2.5	-0.9	-0.6	-1.6	-0.6	-1.4	-0.6	-0.2	-1.1	-0.7	-0.3	-0.9	-1.2	-0.9	-1.0	-0.9	-0.5
Falls in the last year	0.5	0.7	2.8	1.2	1.0	0.9	0.8	-0.0	1.0	-0.3	1.7	1.0	0.6	0.6	1.2	0.1	0.8	1.1	0.5
Hair/balding pattern: Pattern 3	0.5	0.7	2.5	0.3	-1.6	1.1	-0.5	1.5	0.3	1.3	0.2	-0.9	-1.0	0.9	1.3	-0.2	0.6	-0.1	-0.7
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	2.2	-1.0	0.2	-1.5	-0.8	-0.9	-0.8	-0.5	-0.2	-0.8	-0.8	-0.7	-0.3	-0.3	-0.4	-1.2	-0.9
Blood clot in the leg (DVT)	0.5	0.6	6.6	1.2	0.3	2.6	1.0	1.0	0.2	0.1	0.3	0.5	0.4	0.3	0.2	0.3	0.2	0.3	0.5
High blood pressure (siblings)	0.5	0.8	2.9	-0.5	-0.1	-0.2	-0.8	0.2	-0.6	-0.8	-1.4	-1.0	-0.7	-1.1	-1.7	-1.3	-0.7	-1.1	-0.9
Mean time to correctly identify matches	0.5	0.9	5.3	0.1	1.3	1.6	-0.2	2.3	0.3	1.5	0.7	-0.3	-0.6	0.6	1.2	0.6	0.9	-0.3	-0.6
Illness, injury, bereavement, stress in last 2 years	0.5	0.7	4.9	0.2	-1.5	1.4	-0.2	2.2	0.6	-0.3	-0.2	-0.2	-0.3	0.5	0.7	-0.1	0.2	1.2	-0.0
Medication for cholesterol	0.5	0.7	2.1	-0.4	-1.2	1.3	-0.8	1.5	-0.1	0.4	-0.2	-1.2	-1.3	0.5	1.1	0.6	0.0	0.3	-1.1
Osteoarthritis (self-reported)	0.5	0.6	1.8	-0.3	0.9	-0.5	-0.3	-1.3	-1.0	-0.8	0.4	-0.5	-0.5	-1.2	-0.4	-1.3	-0.8	-1.1	-0.4
High cholesterol (Self-reported)	0.5	0.9	2.7	0.9	1.3	-0.8	1.1	-0.4	0.9	0.8	1.1	1.5	1.6	0.6	0.5	0.7	0.8	0.5	1.6
Medication: Paracetamol	0.5	0.7	3.1	-0.9	0.6	-1.8	-1.0	-1.5	-0.8	-0.6	0.7	-0.8	-1.0	-0.8	0.1	-1.1	-0.4	-0.3	-0.8
Fractured/broken bones in last 5 years	0.5	0.7	1.6	1.0	-0.1	0.4	0.8	1.0	1.1	1.3	1.2	0.9	0.8	0.7	0.9	-0.3	1.0	0.6	0.7
Depressed Affect (Nagel 2018)	0.4	0.9	3.3	-1.0	-0.8	-0.9	-0.5	-0.9	-1.0	-1.7	-1.4	-0.4	-0.4	-1.1	-1.8	-0.6	-1.2	-0.5	-0.6
Depression (Nagel 2018)	0.4	0.6	1.7	-0.6	-1.0	-0.9	-0.5	-1.2	-1.0	-1.3	-0.6	-0.5	-0.5	-0.6	-1.0	-0.8	-1.1	-0.2	-0.4
Intelligence (Savage-Jansen 2018)	0.4	1.3	9.6	1.3	-1.4	1.2	1.2	-0.0	-0.7	-3.1	-0.5	1.0	0.5	-1.1	-1.4	-1.0	-1.2	0.6	0.1
Neuroticism (Nagel 2018)	0.4	0.9	2.5	0.8	-0.1	0.7	1.0	1.1	1.1	1.6	0.6	0.9	1.0	1.5	1.1	1.1	1.1	0.8	1.0
Alzheimer’s Disease (including proxy)	0.4	0.5	1.2	0.9	1.0	0.4	0.7	0.2	0.8	0.7	0.7	0.8	0.8	1.0	0.4	1.1	0.9	0.7	0.8
Reaction Time	0.4	0.8	3.2	-0.0	1.8	1.0	-0.2	1.8	0.3	1.4	0.7	-0.2	-0.7	0.5	1.3	0.4	0.9	-0.5	-1.0
Rheumatoid Arthritis	0.4	0.5	1.5	1.1	0.4	1.0	1.2	-0.4	0.2	-0.6	-0.2	0.6	1.0	0.3	-0.6	0.9	0.0	0.4	1.1
Cardiovascular Disease	0.4	1.4	5.1	-0.8	0.9	-1.5	-0.3	-1.3	-1.1	-1.5	-0.8	0.1	0.1	-2.0	-2.2	-2.3	-1.3	-0.8	0.0
Respiratory disease	0.4	0.8	3.6	1.2	-0.2	0.3	1.4	0.8	1.1	1.9	0.4	1.0	1.4	0.6	0.9	0.2	0.7	-0.2	0.9
Hearing difficulty/problems: Yes	0.4	0.6	3.2	0.7	-0.5	-1.6	0.8	-1.8	0.6	0.2	-0.0	0.9	1.0	0.1	-0.3	-0.1	0.3	-0.2	0.6
Relative age of first facial hair	0.4	0.9	2.9	1.3	-0.7	0.8	1.5	-0.3	0.9	-0.0	0.5	1.7	1.5	0.8	0.2	1.2	0.9	0.8	1.1
Medication: Metformin	0.4	0.5	2.6	0.6	-0.4	-0.8	0.7	-1.3	-0.1	1.2	-0.0	0.4	1.1	0.4	-0.4	0.2	-0.0	-0.7	1.6
Multivitamins +/- minerals	0.4	0.5	2.0	-1.1	0.2	-1.0	-0.9	0.2	0.0	1.4	-0.4	-0.9	-0.5	0.1	0.5	0.3	0.3	-1.1	-0.4
Financial difficulties in last 2 years	0.4	0.6	3.9	-0.5	0.2	-1.8	0.2	-2.0	0.3	0.6	-0.5	0.3	0.7	0.0	-0.7	-0.0	0.2	-0.9	0.4
Mouth/teeth dental problems	0.4	0.5	2.0	-0.4	0.1	0.9	-0.8	1.4	-0.5	-0.5	-0.3	-1.1	-1.4	-0.5	0.3	-0.2	-0.4	-0.1	-1.4
Hayfever/allergic rhinitis (self-reported)	0.4	0.5	2.8	0.3	0.0	-0.3	0.2	1.7	0.7	0.9	1.1	0.5	0.0	0.6	1.3	0.2	0.8	1.1	-0.1
Medication: Simvastatin	0.4	0.6	2.0	0.7	1.2	-0.5	1.0	-0.6	0.4	0.9	0.6	1.1	1.4	0.3	-0.1	-0.1	0.3	-0.2	1.4
Illnesses of siblings	0.4	0.6	4.0	0.3	0.4	0.4	0.4	0.1	0.5	0.5	1.4	0.8	0.0	0.8	2.0	0.9	0.7	1.0	0.0
Alcohol intake versus 10 years previously	0.4	0.7	1.5	-1.2	-1.1	-0.5	-1.1	0.3	-0.6	0.8	-0.6	-1.1	-1.1	-0.4	-0.1	-1.2	-0.4	-1.1	-1.0
Qualifications: A levels/AS levels or equivalent	0.4	0.8	5.3	0.8	-0.5	2.1	0.2	2.3	0.1	-0.3	0.5	0.1	-0.5	0.5	0.9	-0.0	0.1	1.3	-0.1
Medication: Cholesterol lowering	0.4	0.6	3.2	-0.1	0.8	-1.5	0.3	-1.8	-0.1	0.9	-0.5	0.5	0.9	-0.1	-1.3	0.4	-0.0	-0.9	0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	0.4	0.6	2.1	0.7	0.3	-0.1	1.1	-0.3	0.5	1.2	0.8	1.4	1.4	0.8	0.3	0.2	0.5	0.3	1.4
Medication: Paracetamol	0.4	0.7	2.9	-1.1	0.6	-1.7	-1.1	-1.0	-0.8	-0.5	0.5	-0.9	-1.1	-0.8	0.2	-0.8	-0.6	0.1	-0.9
Gout (self-reported)	0.4	0.5	3.0	0.4	1.7	-0.5	0.6	-1.1	0.5	0.8	0.6	0.6	1.0	0.5	0.2	0.4	0.9	-0.6	0.8
Hypothyroidism/myxoedema (self-reported)	0.4	0.9	5.8	-0.7	-1.7	-2.1	-0.5	-2.4	-0.3	-0.4	-0.6	-0.6	-0.0	-0.1	-0.4	-0.3	-0.3	-0.5	0.3
Number of children fathered	0.4	0.4	4.1	0.8	2.0	0.9	0.6	0.4	-0.3	-0.3	0.1	0.5	0.4	-0.5	-0.6	-0.2	-0.3	-0.5	0.1
Medication: Seretide 50 evohaler	0.4	0.5	1.8	1.1	1.4	0.4	1.2	-0.0	0.4	0.8	0.7	0.8	1.0	0.2	0.3	0.4	0.3	0.1	1.0
Number of full sisters	0.4	0.5	3.1	-0.5	0.1	-1.8	-0.1	-1.1	-0.0	1.0	-0.7	-0.1	0.3	-0.2	-0.6	-0.1	-0.2	-1.3	-0.0
Had major operations	0.4	0.5	3.1	-0.7	1.1	-0.6	-0.5	-0.3	-0.3	1.2	-0.2	-0.5	-0.5	-0.5	-0.2	-0.9	-0.2	-1.8	-0.7
Supplements: Vitamin C	0.4	0.5	1.3	-1.0	-0.5	-0.6	-1.0	-0.1	-0.7	-0.1	-0.6	-1.1	-1.1	-0.5	-0.1	-0.7	-0.6	-1.0	-0.9
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	1.8	0.5	1.4	-0.5	0.7	-0.1	0.6	1.2	0.1	0.6	1.0	0.7	0.2	0.9	0.5	-0.1	1.0
Medication: Gliclazide	0.4	0.4	1.4	-0.1	-0.3	0.7	-0.5	0.6	-0.9	-0.4	-0.2	-0.9	-0.9	-0.8	-0.4	-1.2	-0.8	-0.7	-0.6
Average weekly champagne plus white wine intake	0.4	0.6	2.7	0.3	0.8	0.2	0.2	0.6	0.6	0.7	1.6	0.7	0.2	0.8	1.5	0.6	0.7	1.1	0.3
Wears glasses or contact lenses	0.4	0.5	2.0	-0.7	-1.4	-0.8	-0.8	-0.8	-0.4	-0.0	-0.1	-0.3	-0.8	-0.7	-0.0	-1.3	-0.6	-0.0	-0.8
Medication: Blood pressure	0.4	0.7	3.5	-0.2	0.4	-0.9	-0.0	-0.7	-0.6	-1.5	-0.2	0.6	0.3	-1.2	-1.4	-1.9	-0.9	-0.2	-0.1
Unable to work because of sickness or disability	0.4	0.5	3.2	-0.0	1.1	-1.4	0.1	-1.8	-0.1	0.6	0.9	0.2	0.6	-0.1	-0.3	-0.1	-0.0	-0.2	0.9
Cholesterol lowering medication	0.4	0.6	1.9	0.5	1.0	-1.1	0.7	-0.1	0.5	-0.0	1.1	1.4	1.2	0.1	0.5	-0.7	0.4	0.3	1.0
Bipolar Disorder (2018)	0.3	0.5	4.6	0.6	2.1	-0.5	0.4	0.1	0.2	-0.5	1.1	0.7	0.6	-0.5	0.0	-0.6	-0.0	0.7	0.6
Ulcerative Colitis (UC)	0.3	0.5	5.0	0.5	-0.4	-0.5	0.7	-2.2	0.3	-0.1	0.1	0.6	1.0	-0.2	-0.8	-0.5	0.1	-0.4	0.8
Ovarian Cancer	0.3	0.4	2.4	-0.1	-0.9	-0.0	-0.4	0.1	-0.7	-1.2	0.1	-0.1	-0.2	0.4	-0.4	1.0	-0.5	1.6	0.6
LDL Cholesterol	0.3	0.5	2.5	0.7	1.6	0.2	0.8	-0.7	0.2	0.1	0.3	0.9	0.9	0.3	-0.4	1.1	0.0	0.5	0.9
Lupus	0.3	0.4	2.0	-0.1	-0.4	0.6	-0.6	1.1	-0.4	-0.0	0.9	-0.5	-1.0	0.2	1.4	-0.5	-0.2	0.1	-0.8
Type 2 Diabetes (T2D) (2012)	0.3	0.3	2.9	0.7	0.7	1.1	0.3	1.7	-0.2	0.6	0.0	0.3	-0.1	0.0	0.1	-0.1	-0.1	0.3	-0.1
Ulcerative Colitis	0.3	0.5	1.7	0.9	0.3	-0.0	1.0	-1.0	0.7	0.3	0.5	0.9	1.3	0.4	-0.1	0.5	0.5	0.0	1.3
Hypothyroidism (self reported)	0.3	0.7	5.1	-0.3	-1.5	-1.4	-0.1	-2.3	-0.4	-0.4	-0.8	-0.4	0.2	-0.4	-0.8	-0.6	-0.6	-0.5	0.5
Fed-up feelings	0.3	0.6	2.4	-0.7	0.4	-1.3	-0.1	-1.5	-0.5	-0.4	-1.0	-0.2	0.0	-0.7	-1.5	-0.4	-0.6	-1.3	-0.4
Age when periods started (menarche)	0.3	0.7	6.5	-0.0	0.4	1.3	-0.4	2.5	0.1	-0.2	-0.1	-0.1	-1.0	0.3	0.4	0.9	0.5	0.6	-1.4
Alcohol usually taken with meals	0.3	0.6	2.7	-0.6	0.5	-1.0	-0.6	0.4	0.4	-1.0	1.1	0.2	-0.5	0.3	1.5	0.2	0.2	1.6	-0.4
Diabetes (self-reported)	0.3	0.5	3.0	-0.1	0.3	-1.5	0.2	-1.0	-0.2	1.7	0.4	0.3	0.7	0.4	0.1	0.1	0.1	-0.9	1.1
Mouth/teeth dental problems: Dentures	0.3	0.6	3.0	-0.2	-0.3	-0.9	0.1	-1.7	-0.4	-0.4	-0.5	0.3	0.8	-0.7	-1.2	-1.1	-0.6	-0.8	0.9
Asthma	0.3	0.5	1.3	1.1	-0.6	0.5	1.1	1.1	0.6	0.5	0.8	0.8	0.9	0.5	0.8	-0.1	0.3	0.8	0.8
Lung cancer (father)	0.3	0.4	2.4	0.1	1.5	1.3	-0.1	0.5	-0.6	0.0	-0.3	-0.5	-0.3	-0.6	-0.6	-0.3	-0.5	-0.7	-0.2
Length of working week for main job	0.3	0.3	0.7	0.6	0.2	0.4	0.8	-0.1	0.8	-0.1	0.5	0.8	0.8	0.4	0.5	0.1	0.7	0.9	0.7
Qualifications: O levels/GCSEs or equivalent	0.3	0.6	3.7	0.5	-0.2	1.6	0.1	1.9	-0.3	-0.9	-0.6	-0.3	-0.6	-0.6	-0.2	-0.4	-0.7	0.5	-0.7
Medication: Amlodipine	0.3	0.4	2.5	0.1	0.5	-0.1	0.1	0.6	-0.3	-0.4	-0.9	0.2	0.1	-0.8	-1.6	-1.0	-0.8	-0.7	-0.2
Number of full brothers	0.3	0.3	1.5	-0.4	-1.0	-1.0	-0.6	-1.2	-0.1	0.8	0.0	-0.8	-0.4	0.1	-0.1	-0.0	0.1	-0.7	-0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.4	1.6	0.4	0.6	0.5	0.4	-0.3	0.6	1.3	0.8	0.7	0.7	1.0	0.7	0.3	0.6	0.2	0.6
Pulse rate, automated reading	0.3	0.9	4.0	0.2	2.0	-1.7	0.7	-0.0	0.9	1.2	1.0	1.1	1.0	0.5	0.9	1.0	0.9	0.3	0.8
Overall health rating	0.3	0.6	2.9	0.2	1.4	-1.7	0.5	-0.9	0.9	1.3	0.2	0.6	1.1	0.0	0.2	-0.8	0.4	-0.8	0.6
Chest pain or discomfort	0.3	0.5	2.5	-0.4	0.3	-0.6	-0.4	-1.6	-0.7	-0.1	-0.4	-0.6	-0.4	-0.7	-0.8	-0.6	-0.4	-1.3	-0.6
Illnesses of father: Heart disease	0.3	0.4	1.6	0.7	0.8	-0.1	1.0	-0.9	-0.2	0.1	-0.3	0.5	1.0	-0.5	-1.2	-0.2	-0.2	-0.7	1.1
Mood swings	0.3	0.6	2.3	0.5	1.5	0.8	0.7	0.4	0.2	-1.0	1.2	1.0	0.4	0.4	0.3	0.7	0.2	1.3	0.4
Long-standing illness, disability or infirmity	0.3	0.5	2.8	0.2	0.2	-1.7	0.2	-1.0	0.4	1.2	0.9	0.7	0.7	0.3	0.4	-0.7	0.5	-0.6	0.6
Breast cancer (self-reported)	0.3	0.4	2.1	0.7	-0.3	0.7	0.4	1.4	0.7	1.5	-0.1	-0.0	0.2	0.6	0.8	0.3	0.7	-0.4	-0.1
Financial situation satisfaction	0.3	0.4	2.1	-0.8	0.3	-1.5	-0.3	-0.9	0.1	1.0	-0.2	-0.1	-0.0	0.0	-0.1	-0.6	0.2	-1.2	-0.4
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.9	-0.3	-0.8	-0.8	-0.5	-1.2	-0.4	0.6	-0.2	-0.5	-0.4	-0.7	-0.1	-1.4	-0.5	-0.7	-0.3
Basal cell carcinoma (self-reported)	0.3	0.4	1.3	0.5	0.6	-0.1	0.4	-0.0	0.7	1.1	0.3	0.3	0.7	1.0	0.2	1.2	0.8	0.3	0.8
Heart disease (siblings)	0.3	0.4	2.0	0.3	0.4	-0.0	0.5	-0.3	-0.2	1.3	-0.4	0.1	0.6	-0.3	-0.8	-0.4	-0.3	-1.4	0.7
Alzheimer’s Disease (in mother)	0.2	0.3	2.0	0.6	1.4	0.9	0.3	-0.4	-0.2	0.6	0.6	0.4	-0.1	-0.2	0.3	-0.5	0.0	-0.4	-0.2
Bipolar Disorder (2011)	0.2	0.2	2.5	0.3	1.6	-0.4	-0.0	0.0	0.2	0.8	0.5	0.0	0.1	-0.0	0.3	-0.5	0.1	-0.3	0.1
Coronary Artery Disease (CAD)	0.2	0.3	1.0	-0.5	0.6	0.0	-0.5	-0.3	-0.6	-0.8	-0.2	-0.7	-0.5	-1.0	-0.8	-0.2	-0.4	-0.8	-0.4
Blood Platelet Count	0.2	2.2	7.1	1.5	0.8	0.8	2.0	0.3	1.1	0.1	0.6	2.2	2.4	1.4	-0.5	2.5	1.1	1.5	2.7
Neuroticism	0.2	0.5	2.4	-0.7	-0.5	-0.1	-0.4	-0.5	-0.8	-1.3	-1.3	-0.4	-0.2	-0.7	-1.6	-0.3	-1.0	-0.4	-0.2
Sensitivity / hurt feelings	0.2	0.4	0.9	1.0	0.2	0.9	1.0	-0.1	-0.1	-0.9	-0.6	0.6	0.8	-0.0	-1.0	0.6	-0.4	0.2	0.6
Medication: Co-codamol	0.2	0.3	0.9	0.3	-0.9	-0.4	0.2	0.5	0.7	0.9	0.7	0.3	0.4	0.7	0.5	-0.1	0.8	0.2	0.4
Maternal smoking around birth	0.2	0.2	2.9	0.2	1.7	0.2	0.1	-0.1	-0.2	0.4	0.5	-0.1	0.4	-0.0	0.3	0.5	0.1	-0.1	0.6
Relative age voice broke	0.2	0.4	2.2	0.2	-1.5	0.0	0.3	-0.2	0.4	-1.1	0.1	0.8	0.4	0.4	-0.5	0.6	0.6	0.9	0.1
Number of live births	0.2	0.3	1.1	-0.7	-0.4	-0.6	-0.5	-0.6	-0.2	-0.7	-0.5	-0.4	-0.3	-0.6	-0.8	-1.1	-0.4	-0.8	-0.6
Pulse rate	0.2	0.3	1.1	0.1	0.9	-1.0	0.5	-0.3	0.7	0.3	0.3	0.4	0.9	0.3	0.2	0.6	0.7	0.3	0.8
Hair/balding pattern: Pattern 4	0.2	0.4	2.0	-0.3	0.2	-0.6	-0.3	-1.4	-0.7	-0.9	-0.8	-0.5	-0.1	-0.8	-0.7	-0.3	-1.0	-0.4	-0.1
Birth weight	0.2	0.5	5.5	0.3	0.4	1.0	0.1	0.7	0.2	-2.4	0.2	0.3	0.0	-0.1	-0.2	0.3	0.1	1.4	-0.1
Chronic bronchitis/emphysema (mother)	0.2	0.3	1.0	0.4	0.8	-0.2	0.4	-0.1	0.6	0.4	1.0	0.4	0.4	0.5	0.5	0.2	0.7	0.7	0.6
Shortness of breath walking on level ground	0.2	0.3	2.9	-0.7	-0.6	-1.7	-0.4	-0.6	0.2	0.0	0.4	0.1	-0.1	0.4	0.4	0.1	0.2	0.3	-0.1
Medication: Allopurinol	0.2	0.3	2.0	-0.5	1.4	-0.6	-0.3	-0.8	0.1	0.1	0.3	-0.1	0.2	0.3	-0.1	0.5	0.6	-0.5	0.2
Leg pain on walking	0.2	0.3	1.6	-0.1	0.8	-1.0	0.4	-1.3	0.2	0.2	0.0	0.5	0.5	-0.5	-0.3	-0.1	0.3	-1.0	-0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.2	2.4	0.1	1.5	-0.5	-0.2	-0.9	-0.3	-0.3	0.5	0.2	-0.0	-0.3	-0.4	-0.3	-0.1	-0.3	0.1
Diabetes diagnosed by doctor	0.2	0.3	1.6	0.2	-0.0	-0.7	0.4	-0.7	-0.4	1.3	0.1	0.2	0.6	0.1	-0.3	-0.1	-0.3	-0.8	1.0
Eye problems/disorders: Cataract	0.2	0.3	2.2	0.3	1.5	0.1	0.5	-0.1	0.2	-0.3	0.5	0.7	0.5	0.2	-0.8	0.4	0.4	0.3	0.6
Mouth/teeth dental problems: Mouth ulcers	0.2	0.3	1.1	0.2	1.1	-0.1	0.3	0.9	0.1	1.1	0.7	0.1	0.2	0.5	0.5	0.6	0.4	0.4	0.6
Back pain experienced in last month	0.2	0.3	1.6	-0.4	1.2	-0.5	-0.8	0.3	-0.5	0.1	-0.0	-0.7	-0.7	-0.7	0.0	-0.8	-0.5	-0.5	-0.9
Asthma (self-reported)	0.2	0.4	0.9	0.9	-0.8	0.4	1.0	0.9	0.5	0.6	0.5	0.7	0.8	0.3	0.7	-0.4	0.1	0.5	0.6
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.2	0.3	3.4	0.4	1.8	0.5	0.1	-0.0	-0.3	-1.1	0.6	0.1	-0.2	-0.5	-0.5	-0.0	-0.2	0.5	0.1
Number of self-reported non-cancer illnesses	0.2	0.3	1.7	0.3	0.2	-0.9	0.4	-1.3	0.1	0.5	0.7	0.6	0.6	-0.2	-0.2	-0.9	0.3	-0.4	0.5
Tinnitus: Yes, now most or all of the time	0.2	0.3	2.8	0.2	0.2	-0.2	0.3	-1.7	-0.5	-0.8	0.2	0.4	0.3	-0.4	-0.4	-0.6	-0.3	-0.5	0.1
Alcohol drinker status: Never	0.2	0.2	1.4	0.1	0.4	1.2	-0.2	-0.1	-0.5	-0.5	-0.3	-0.6	-0.6	-0.4	-0.1	-0.5	-0.4	-0.6	-0.6
Average weekly beer plus cider intake	0.2	0.2	1.1	0.4	-0.2	-0.3	0.4	0.7	0.4	1.0	0.2	0.2	0.3	0.6	0.6	0.7	0.4	0.3	0.4
Age started oral contraceptive pill	0.2	0.2	1.6	-0.1	0.3	-1.3	0.0	-0.6	0.0	0.2	0.7	0.5	0.6	0.4	-0.1	0.5	0.4	0.1	0.8
Prostate Cancer	0.1	0.2	1.7	0.1	-1.3	-0.3	0.1	-0.1	0.1	0.4	-0.7	0.1	0.3	0.4	-0.3	-0.1	-0.2	0.2	0.7
Mean Putamen Volume	0.1	0.1	0.4	-0.2	-0.2	0.3	-0.3	0.7	0.0	-0.3	-0.1	-0.4	-0.2	0.1	-0.2	0.3	0.2	0.5	0.2
Blood Eosinophil Count	0.1	1.0	4.0	1.0	-0.8	0.5	1.1	-1.0	-0.0	-1.1	-0.7	0.8	1.2	-1.4	-1.4	-2.0	-0.7	-0.7	0.9
Blood Red Count	0.1	0.9	5.2	1.0	-0.3	1.4	0.9	0.2	-0.2	-1.5	0.9	1.0	0.3	-1.1	0.0	-2.3	-0.6	1.1	0.1
Hair Pigment	0.1	3.3	13.1	1.6	0.8	2.7	1.2	-1.2	-2.2	-3.6	1.2	1.6	0.7	-1.9	-3.1	-1.6	-1.9	0.9	1.3
Stomach or abdominal pain in last month	0.1	0.2	0.7	0.0	0.1	0.1	-0.1	-0.5	-0.2	0.7	0.1	-0.2	-0.5	0.0	0.1	-0.6	-0.2	-0.9	-0.8
Frequency of tenseness / restlessness in last 2 weeks	0.1	0.2	1.6	0.3	0.3	1.3	0.1	0.6	-0.1	0.4	0.7	0.3	-0.3	0.0	0.1	-0.9	-0.1	0.4	-0.3
Prospective memory result	0.1	0.2	1.1	0.4	0.6	-0.1	0.3	-0.4	-0.1	1.1	0.6	0.5	0.3	0.0	0.2	-0.4	0.1	-0.5	0.3
Exposure to tobacco smoke at home	0.1	0.2	1.0	-0.3	1.0	0.6	-0.3	0.3	0.0	0.5	-0.3	-0.6	-0.3	0.1	0.3	-0.2	0.1	-0.6	-0.4
Ever highly irritable/argumentative for 2 days	0.1	0.1	0.4	0.1	-0.1	-0.5	0.4	-0.5	0.6	0.3	0.5	0.6	0.4	0.3	0.5	0.1	0.4	0.4	-0.0
Medication: Ventolin 100micrograms inhaler	0.1	0.2	1.5	0.2	0.2	0.9	0.2	1.2	-0.2	0.0	0.2	-0.2	-0.2	-0.3	0.3	-0.3	-0.2	-0.1	-0.2
Neck or shoulder pain in last month	0.1	0.1	0.5	-0.1	0.5	-0.1	-0.0	-0.6	0.2	0.7	0.4	-0.0	0.2	0.5	0.2	0.7	0.2	0.2	0.5
Mother’s age at death	0.1	0.1	1.0	-0.3	-1.0	-0.1	-0.3	-0.0	-0.3	0.4	-0.5	-0.3	-0.2	-0.1	-0.6	-0.3	-0.1	-0.3	-0.1
Supplements: Fish oil (including cod liver oil)	0.1	0.1	0.8	-0.4	0.4	-0.0	-0.3	0.4	0.4	0.9	0.2	0.0	-0.1	0.1	0.2	-0.1	0.4	-0.3	-0.1
Diastolic blood pressure, automated reading	0.1	0.4	3.1	-0.1	1.8	-1.0	0.2	0.5	0.4	0.4	0.7	0.8	0.1	-0.4	0.3	-0.9	0.2	0.3	-0.2
Neuroticism score	0.0	0.1	0.2	-0.1	0.1	-0.2	0.3	-0.1	-0.0	-0.3	-0.1	0.4	0.3	0.2	-0.0	0.4	-0.3	0.4	0.2
Irritability	0.0	0.1	0.2	0.5	-0.1	0.2	0.5	0.1	-0.2	0.2	-0.1	0.3	0.4	0.1	-0.4	-0.0	-0.3	-0.1	0.4

Hub : Genes

POMC

Models

Trait associations