Best TWAS P=1.42e-09 · Best GWAS P=4.39e-12 conditioned to 4.02e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Hypothalamus | PDE1A | 0.24 | -0.01 | enet | 21 | -0.01 | 0.75800 | -5.4 | -6.0 | 1.4e-09 | -0.60 | 0.07 | 0.31 | TRUE |
| 2 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | PDE1A | 0.05 | 0.04 | blup | 206 | 0.04 | 0.00005 | 4.4 | -5.4 | 6.3e-08 | -0.42 | 0.65 | 0.02 | FALSE |