Best TWAS P=8.43e-12 · Best GWAS P=9.83e-12 conditioned to 0.0019
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | WDR75 | 0.05 | 0.04 | lasso | 2 | 0.03 | 0.0012 | -6.3 | 6.4 | 1.3e-10 | -0.85 | 0.06 | 0.78 | FALSE |
| 2 | GTEx | Breast Mammary Tissue (Male) | WDR75 | 0.16 | 0.00 | lasso | 9 | 0.00 | 0.2640 | -6.3 | 5.8 | 5.4e-09 | -0.73 | 0.04 | 0.29 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | WDR75 | 0.05 | 0.04 | lasso | 4 | 0.03 | 0.0012 | -6.3 | 6.3 | 2.9e-10 | -0.89 | 0.04 | 0.94 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | COL5A2 | 0.04 | 0.00 | blup | 79 | 0.02 | 0.0059 | -6.5 | 6.8 | 8.4e-12 | -0.65 | 0.02 | 0.75 | TRUE |