[Hub]/) : Traits : Impedance of whole body : ← →

chr2:197,134,790-200,117,777

Best TWAS P=1.89e-32 · Best GWAS P=1.82e-32 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
19	GTEx	Skin Sun Exposed Lower leg	MARS2	0.04	0.05	enet	8	0.03	1.2e-03	11.76	-11.9	1.9e-32	-0.98	0.06	0.94	TRUE
14	GTEx	Lung	RFTN2	0.06	0.08	lasso	8	0.06	2.7e-05	11.84	11.8	6.1e-32	0.99	0.04	0.96	FALSE
20	GTEx	Spleen	RFTN2	0.11	0.03	enet	26	0.05	2.4e-02	11.69	11.7	2.3e-31	0.96	0.05	0.65	FALSE
21	GTEx	Spleen	MARS2	0.12	0.04	lasso	5	0.00	3.4e-01	11.73	-11.5	1.1e-30	-0.94	0.05	0.50	FALSE
27	GTEx	Whole Blood	PLCL1	0.08	0.08	enet	15	0.05	4.1e-05	11.31	11.0	2.8e-28	0.89	0.31	0.69	FALSE
25	GTEx	Thyroid	PLCL1	0.04	0.01	lasso	4	0.00	2.6e-01	11.49	11.0	5.2e-28	0.89	0.16	0.60	FALSE
38	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	RFTN2	0.05	0.01	blup	61	0.02	3.1e-02	7.49	10.3	1.1e-24	0.81	0.04	0.39	FALSE
26	GTEx	Thyroid	RFTN2	0.04	0.01	enet	11	0.01	9.5e-02	11.73	10.3	1.2e-24	0.87	0.07	0.80	FALSE
3	GTEx	Adipose Subcutaneous	RFTN2	0.14	0.10	enet	11	0.13	5.3e-11	11.29	10.2	1.5e-24	0.87	0.12	0.88	FALSE
24	GTEx	Thyroid	SF3B1	0.04	0.02	enet	14	0.02	2.0e-02	7.74	10.1	5.7e-24	0.83	0.07	0.86	FALSE
7	GTEx	Breast Mammary Tissue (Female)	SF3B1	0.05	-0.01	lasso	3	-0.01	8.1e-01	7.49	9.8	8.9e-23	0.75	0.05	0.09	FALSE
34	YFS	Blood	PLCL1	0.10	0.10	lasso	9	0.14	1.5e-43	11.42	9.7	3.6e-22	0.84	0.75	0.25	FALSE
32	ROSMAP	Brain Pre-frontal Cortex	MARS2	0.05	0.03	enet	14	0.05	2.2e-07	-8.07	-9.4	5.5e-21	-0.86	0.06	0.94	FALSE
36	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PLCL1	0.04	0.00	blup	130	0.02	4.0e-03	-2.41	9.4	7.3e-21	0.66	0.04	0.44	FALSE
6	GTEx	Breast Mammary Tissue	SF3B1	0.06	0.06	lasso	4	0.03	6.6e-03	7.43	9.1	1.1e-19	0.70	0.18	0.66	FALSE
9	GTEx	Cells EBV-transformed lymphocytes	MARS2	0.15	0.14	lasso	4	0.07	2.6e-03	-8.51	-8.6	5.5e-18	-0.76	0.05	0.75	FALSE
30	NTR	Blood	PLCL1	0.02	0.01	enet	14	0.02	1.9e-06	11.29	8.5	2.1e-17	0.71	0.22	0.72	FALSE
23	GTEx	Testis	SF3B1	0.10	0.07	enet	17	0.08	2.6e-04	7.50	8.2	1.9e-16	0.63	0.42	0.53	FALSE
8	GTEx	Cells EBV-transformed lymphocytes	HSPD1	0.15	0.04	lasso	7	0.04	2.0e-02	5.78	-8.1	3.9e-16	-0.73	0.11	0.58	FALSE
28	METSIM	Adipose	PLCL1	0.06	0.01	blup	517	0.05	3.6e-08	-3.55	8.1	7.3e-16	0.76	0.12	0.88	FALSE
37	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	MOBKL3	0.03	0.01	blup	32	0.02	6.3e-03	10.29	7.9	3.0e-15	0.72	0.01	0.56	FALSE
15	GTEx	Nerve Tibial	SF3B1	0.06	0.09	lasso	8	0.08	3.3e-06	7.49	7.9	3.5e-15	0.61	0.97	0.02	FALSE
10	GTEx	Colon Transverse	MARS2	0.17	0.12	lasso	4	0.13	7.4e-07	-8.51	-7.9	3.8e-15	-0.69	0.21	0.49	FALSE
12	GTEx	Esophagus Muscularis	SF3B1	0.06	0.02	lasso	4	0.03	1.0e-02	8.00	7.6	2.3e-14	0.49	0.18	0.16	FALSE
2	CommonMind	Brain Pre-frontal Cortex	SF3B1	0.06	0.07	enet	10	0.07	2.5e-09	7.50	7.5	6.4e-14	0.56	1.00	0.00	FALSE
11	GTEx	Esophagus Mucosa	SF3B1	0.04	0.02	lasso	4	0.01	5.7e-02	7.66	7.5	8.4e-14	0.56	0.32	0.07	FALSE
29	NTR	Blood	ANKRD44	0.03	0.00	bslmm	417	0.02	2.7e-06	7.04	-7.3	3.4e-13	-0.54	0.18	0.69	FALSE
31	ROSMAP	Brain Pre-frontal Cortex	SF3B1	0.02	0.01	blup	336	0.01	6.2e-03	7.62	7.1	1.0e-12	0.55	0.56	0.10	FALSE
13	GTEx	Lung	SF3B1	0.06	0.04	enet	23	0.02	2.2e-02	7.66	6.0	2.0e-09	0.53	0.45	0.25	FALSE
1	CommonMind	Brain Pre-frontal Cortex	PLCL1	0.06	0.01	blup	397	0.02	4.9e-04	0.44	5.9	3.5e-09	0.51	0.06	0.56	FALSE
22	GTEx	Testis	ANKRD44	0.33	0.35	enet	15	0.36	6.2e-17	6.01	5.8	6.2e-09	0.45	1.00	0.00	FALSE
17	GTEx	Skin Not Sun Exposed Suprapubic	SF3B1	0.08	0.00	enet	19	0.01	1.6e-01	7.49	5.7	1.4e-08	0.38	0.31	0.05	FALSE
4	GTEx	Adrenal Gland	ANKRD44	0.15	0.05	lasso	5	0.15	3.9e-06	-1.29	-5.7	1.6e-08	-0.46	0.22	0.43	FALSE
33	YFS	Blood	ANKRD44	0.02	0.00	blup	416	0.01	6.3e-04	-1.18	-5.5	2.8e-08	-0.46	0.14	0.46	FALSE
16	GTEx	Pituitary	HSPD1	0.10	0.03	enet	12	0.06	1.3e-02	0.78	5.5	3.8e-08	0.50	0.08	0.33	FALSE
5	GTEx	Brain Frontal Cortex BA9	MARS2	0.18	0.12	lasso	2	0.07	5.1e-03	5.30	-5.3	1.1e-07	-0.53	0.14	0.10	FALSE
18	GTEx	Skin Not Sun Exposed Suprapubic	MARS2	0.22	0.02	enet	30	0.02	3.6e-02	11.70	-5.3	1.2e-07	-0.56	0.06	0.53	FALSE
35	The Cancer Genome Atlas	Breast Invasive Carcinoma	RFTN2	0.02	0.02	lasso	2	0.01	1.1e-03	5.41	5.2	2.3e-07	0.52	0.21	0.27	FALSE