Best TWAS P=5.82e-08 · Best GWAS P=1.57e-07 conditioned to 1.1e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | BBS12 | 0.06 | 0.06 | enet | 9 | 0.06 | 8.7e-08 | -5.0 | -5.4 | 5.8e-08 | 0.14 | 0.03 | 0.96 | TRUE |
2 | GTEx | Artery Tibial | FGF2 | 0.18 | 0.05 | lasso | 3 | 0.02 | 1.3e-02 | -5.0 | -5.2 | 2.3e-07 | 0.36 | 0.01 | 0.80 | FALSE |
3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | CCNA2 | 0.03 | 0.01 | blup | 34 | 0.02 | 1.5e-03 | 4.3 | -5.1 | 2.7e-07 | 0.02 | 0.00 | 0.63 | TRUE |