TWAS hub - FGF2

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Artery Tibial	0.1758	0.0746	3.8e-03	0.052	NA	-0.002	NA	0.018	6.2e-05	NA	0.54000	NA	0.01300
2	GTEx	Breast Mammary Tissue (Female)	0.1956	0.0930	6.0e-03	-0.004	NA	-0.009	NA	-0.010	4.2e-01	NA	0.79000	NA	0.93000
3	TCGA	Kidney Renal Clear Cell Carcinoma	0.0612	0.0249	2.9e-05	0.038	0.047	0.038	NA	0.032	3.5e-05	4.4e-06	0.00004	NA	0.00014

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3
Waist Hip Ratio (WHR)	9.0	40.5	52.1	-7.2	-5.5	-6.3
Trunk fat-free mass	6.3	36.0	49.0	7.0	3.7	6.8
Trunk predicted mass	6.3	35.9	48.7	7.0	3.7	6.8
Medication: Ibuprofen (e.g. Nurofen)	5.6	7.1	10.8	2.7	1.9	3.3
Whole body fat-free mass	5.5	31.2	42.2	6.4	3.3	6.5
Whole body water mass	5.5	31.5	42.6	6.4	3.3	6.5
Arm fat-free mass (right)	5.3	27.4	36.9	5.8	3.3	6.1
Arm predicted mass (right)	5.2	26.4	35.2	5.9	3.1	5.8
Arm fat-free mass (left)	5.1	26.0	35.6	6.0	3.2	5.7
Basal metabolic rate	5.0	27.5	37.0	6.1	3.1	6.0
Arm predicted mass (left)	4.9	24.8	34.6	5.9	3.0	5.5
Impedance of leg (left)	4.6	22.2	31.4	-4.7	-3.6	-5.6
Diabetes (self-reported)	4.5	6.9	12.1	-1.8	-2.3	-3.5
Impedance of leg (right)	4.4	21.4	28.7	-4.8	-3.5	-5.4
Leg fat-free mass (left)	4.4	23.2	34.8	5.2	2.7	5.9
Leg fat-free mass (right)	4.4	23.7	34.6	5.4	2.7	5.9
Leg predicted mass (right)	4.4	23.6	34.3	5.4	2.7	5.9
Leg predicted mass (left)	4.3	22.9	34.0	5.2	2.7	5.8
Type 2 Diabetes (T2D) (2018)	4.0	7.4	11.6	-2.4	-2.2	-3.4
Diabetes diagnosed by doctor	4.0	6.5	10.2	-2.1	-2.2	-3.2
Medication: Ibuprofen	3.9	4.6	9.1	2.0	0.8	3.0
Heart disease (siblings)	3.9	4.7	8.6	-2.9	-1.6	-1.8
Impedance of whole body	3.9	19.6	26.8	-5.2	-3.8	-4.2
Allergy or Eczema	3.6	9.4	13.2	-3.3	-3.6	-2.0
Impedance of arm (right)	3.5	16.3	23.7	-4.9	-3.6	-3.5
Medication: Gliclazide	3.5	4.0	4.7	-2.2	-1.8	-2.0
Ever unenthusiastic/disinterested for a whole week	3.4	4.1	5.1	2.3	2.2	1.5
Hayfever/allergic rhinitis (self-reported)	3.1	4.1	5.8	-2.4	-2.3	1.2
Tinnitus: Yes, now most or all of the time	3.1	3.6	6.7	-2.6	-1.9	0.6
Asthma	2.9	5.7	8.2	-2.9	-2.8	-1.1
Impedance of arm (left)	2.9	13.4	20.8	-4.6	-3.2	-3.0
Supplements: Glucosamine	2.8	3.6	7.1	1.7	2.7	1.0
Hip circumference	2.8	12.1	19.2	4.4	2.3	3.4
Bipolar Disorder (2011)	2.7	2.6	5.0	-0.9	-2.2	-1.4
Height	2.7	51.8	106.1	6.2	3.3	10.3
Hayfever, allergic rhinitis or eczema	2.7	5.8	9.2	-2.7	-3.0	-1.1
Weight	2.7	13.3	20.1	4.5	2.1	3.9
Knee pain experienced in last month	2.7	4.2	6.6	2.1	2.6	1.3
Medication: Laxatives (e.g. Dulcolax, Senokot)	2.7	3.2	4.7	-2.2	-2.0	-0.9
Mineral and other dietary supplements	2.7	3.6	6.2	-2.0	-2.5	-0.8
Asthma (self-reported)	2.7	5.3	8.1	-2.9	-2.6	-0.9
Medication: Metformin	2.6	3.6	8.5	-0.3	-1.5	-2.9
Medication for pain relief, constipation, heartburn	2.6	4.5	9.3	-3.1	-1.5	-1.4
Had major operations	2.5	2.9	4.5	2.1	1.7	1.3
Blood clot in the leg (DVT)	2.3	2.9	5.1	1.5	1.1	2.3
Basal cell carcinoma (self-reported)	2.3	2.7	4.5	2.1	1.7	0.9
Standing height	2.2	22.2	41.7	4.8	1.4	6.5
Number of children fathered	2.2	2.5	2.8	-1.4	-1.7	-1.6
Deep venous thrombosis (DVT) (self-reported)	2.2	2.8	4.6	1.5	1.2	2.1
Qualifications: nursing, teaching	2.1	3.3	4.6	-1.8	-2.1	-1.3
Friendships satisfaction	2.0	2.5	4.2	1.5	2.1	1.0
Mean Putamen Volume	1.9	2.2	2.9	-1.5	-1.2	-1.7
Townsend deprivation index at recruitment	1.9	2.7	6.6	0.3	1.2	2.6
Allergy	1.9	4.4	7.7	2.4	2.8	0.2
Qualifications: College or University degree	1.9	5.9	7.6	-2.8	-2.0	-2.5
Age at last live birth	1.9	2.7	3.8	-1.2	-1.7	-1.9
Breast Cancer	1.8	4.3	6.4	-2.5	-2.0	-1.6
Lung FVC	1.8	9.0	24.3	-1.6	0.2	-4.9
Medication: Paracetamol	1.8	3.0	8.2	2.9	0.7	0.6
Forced expiratory volume in 1-second (FEV1), predicted	1.8	3.7	5.4	1.9	1.4	2.3
Medication: Atorvastatin	1.8	2.2	3.1	-1.6	-0.9	-1.8
Irritable Bowel Disease (IBD)	1.7	4.0	7.6	-2.0	-2.8	-0.5
Medication: Simvastatin	1.7	2.5	3.7	-1.8	-1.9	-0.7
Pulse rate	1.7	2.8	4.3	-1.7	-1.2	-2.1
Comparative height size at age 10	1.7	9.4	15.7	4.0	1.4	3.2
Chronic bronchitis/emphysema (father)	1.6	1.9	2.6	1.5	1.6	0.8
Hair/balding pattern: Pattern 4	1.6	3.9	4.9	-1.8	-2.2	-1.9
Glaucoma (self-reported)	1.6	1.9	5.4	0.5	0.4	2.3
Smoking status: Previous	1.6	2.4	3.6	1.6	1.9	-0.9
Average weekly beer plus cider intake	1.6	2.3	3.0	1.6	1.7	1.1
Hearing difficulty/problems: Yes	1.5	2.3	4.8	-2.2	-1.4	-0.6
Frequency of unenthusiasm / disinterest in last 2 weeks	1.5	2.0	3.1	1.8	1.6	0.2
Hair/balding pattern: Pattern 3	1.5	2.3	4.4	1.5	2.1	-0.2
Happiness	1.5	1.8	3.2	1.1	1.8	0.9
Family relationship satisfaction	1.5	1.9	2.8	1.1	1.3	1.7
Ever taken oral contraceptive pill	1.5	1.7	2.7	0.7	1.6	1.4
Supplements: Fish oil (including cod liver oil)	1.5	2.0	3.6	1.4	1.9	-0.4
Alzheimer’s Disease (including proxy)	1.4	2.1	4.9	0.6	-0.9	2.2
Type 2 Diabetes (T2D) (2012)	1.4	1.6	3.8	-0.8	-0.6	-2.0
Angina	1.4	1.9	2.9	-1.7	-1.5	-0.6
Relative age voice broke	1.4	2.1	5.0	0.5	1.0	2.2
Alcohol usually taken with meals	1.4	2.2	5.1	-1.2	-2.3	0.2
Had other major operations	1.4	1.7	3.3	-1.1	-1.8	-0.8
Alcohol intake versus 10 years previously	1.4	2.0	3.9	1.5	0.1	2.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.4	1.7	2.7	-1.6	-1.1	-1.1
Mood swings	1.4	2.5	5.8	2.4	1.3	-0.1
Hearing aid user	1.4	1.5	4.1	-2.0	-0.7	-0.1
Medication: Paracetamol	1.4	2.2	5.6	2.4	0.9	0.3
Alzheimer’s Disease (in mother)	1.3	1.6	2.7	0.1	-1.6	1.4
Alzheimer’s Disease (in father)	1.3	1.5	3.8	0.8	-0.0	1.9
Medication: Atenolol	1.3	1.6	2.9	1.2	1.7	-0.7
Hair/balding pattern: Pattern 2	1.3	1.7	4.9	0.3	2.2	0.3
Mouth/teeth dental problems: Loose teeth	1.3	1.6	2.1	1.5	1.2	1.1
Pain experienced in last month	1.3	2.2	3.2	-1.8	-1.2	-1.4
Fasting Glucose	1.2	1.4	1.8	-1.3	-1.1	-1.1
Schizophrenia (2014)	1.2	2.6	4.0	0.9	1.7	2.0
Supplements: Zinc	1.2	1.3	3.0	1.7	0.7	-0.6
Sitting height	1.2	8.5	21.1	2.1	0.1	4.6
Medication: Lansoprazole	1.2	1.3	3.4	-1.8	0.2	-0.8
Arm fat mass (right)	1.2	4.8	8.7	2.9	1.5	1.9
Loud music exposure frequency	1.2	1.3	3.4	-0.3	0.6	1.9
Worry too long after embarrassment	1.2	2.0	2.7	1.4	1.6	1.1
Age at first live birth	1.2	2.1	3.6	-0.7	-1.9	-1.5
Angina (self-reported)	1.2	1.6	2.4	-1.6	-1.4	-0.7
Arm fat mass (left)	1.2	4.8	8.1	2.8	1.5	2.0
Commuting to job workplace: Public transport	1.2	1.4	3.6	-0.6	0.4	1.9
Ever smoked	1.2	2.0	3.9	2.0	1.5	-0.3
Depressed Affect (Nagel 2018)	1.1	2.3	4.1	2.0	1.6	0.6
Depression (Nagel 2018)	1.1	1.6	3.0	1.3	1.7	0.1
Crohns Disease (2017)	1.1	2.4	5.1	-1.4	-2.3	0.3
Ulcerative Colitis (UC)	1.1	2.1	3.3	-1.5	-1.8	-0.8
Coronary Artery Disease (CAD)	1.1	1.3	2.8	1.7	0.6	-0.8
Number of live births	1.1	1.5	1.7	-1.3	-1.0	-1.3
Peak expiratory flow (PEF)	1.1	2.5	3.2	-1.5	-1.8	-1.4
Back pain experienced in last month	1.1	1.6	4.4	0.6	0.2	2.1
Osteoarthritis (self-reported)	1.1	1.4	2.2	1.4	1.5	0.4
Eye problems/disorders: Glaucoma	1.1	1.3	3.6	0.1	0.6	1.9
Hand grip strength (left)	1.0	2.7	4.9	-1.5	-2.2	-1.1
Ever used hormone-replacement therapy (HRT)	1.0	1.2	2.4	-1.2	0.1	1.5
Pack years adult smoking proportion	1.0	1.6	2.2	1.3	0.9	1.5
Fed-up feelings	1.0	1.9	4.2	2.0	1.1	0.6
Qualifications: CSEs or equivalent	1.0	1.3	2.2	1.3	0.3	1.5
Past tobacco smoking	1.0	1.8	2.7	-1.7	-1.6	0.1
Length of working week for main job	1.0	1.1	2.9	0.6	1.7	0.1
Headache pain in last month	1.0	1.8	4.8	2.2	0.5	0.5
Emphysema/chronic bronchitis	1.0	1.2	3.2	0.0	-0.5	1.8
Illnesses of father: High blood pressure	1.0	1.2	2.8	-0.5	-1.7	-0.7
Pack years of smoking	1.0	1.4	2.2	1.2	0.8	1.5
Neuroticism (Nagel 2018)	0.9	2.0	4.1	2.0	1.4	0.4
Blood Eosinophil Count	0.9	7.0	20.4	-4.5	-0.1	0.7
Systolic Blood Pressure	0.9	4.6	5.4	-2.3	-2.0	-2.1
Eye problems/disorders: Diabetes related eye disease	0.9	1.0	1.6	-0.9	-0.7	-1.3
Vitamin and mineral supplements	0.9	1.2	1.9	-1.4	-0.7	-1.2
Diabetes (mother)	0.9	1.2	3.2	-0.4	0.3	-1.8
Multivitamins +/- minerals	0.9	1.1	2.1	1.0	0.3	1.4
Nervous feelings	0.9	1.7	3.2	1.8	1.3	-0.4
Qualifications: None of the above	0.9	1.9	4.5	0.9	2.1	0.7
Schizophrenia (2018)	0.8	1.6	2.4	0.4	1.6	1.5
Reaction Time	0.8	1.5	2.2	-1.5	-1.5	0.4
Triglycerides	0.8	1.3	3.4	-0.6	-0.1	-1.8
Ulcerative Colitis	0.8	1.2	2.4	-0.9	-1.6	-0.7
Heel T-Score	0.8	6.3	11.9	-2.5	-0.9	-3.5
Ever had hysterectomy (womb removed)	0.8	0.9	1.3	0.7	1.1	1.0
High blood pressure (mother)	0.8	1.1	1.7	-1.3	-0.3	-1.2
Time employed in main current job	0.8	0.9	2.0	0.1	0.8	1.4
Frequency of tiredness / lethargy in last 2 weeks	0.8	1.3	3.3	1.8	0.7	0.4
Hypothyroidism/myxoedema (self-reported)	0.8	1.5	2.9	-1.3	-1.7	-0.1
Commuting to job workplace: Walk	0.8	0.9	2.3	-0.4	-0.5	1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.8	1.8	3.0	-1.7	-0.3	-1.5
Number of self-reported non-cancer illnesses	0.8	1.4	2.8	-0.5	-1.0	-1.7
Mother’s age at death	0.8	1.0	2.4	-0.3	-0.7	-1.6
Commuting to job workplace: Cycle	0.8	1.0	1.3	-0.9	-1.1	1.0
Cholesterol lowering medication	0.8	1.2	3.3	-1.8	-0.5	-0.3
Worry (Nagel 2018)	0.7	1.4	2.7	1.6	1.0	0.7
Hypothyroidism (self reported)	0.7	1.5	4.0	-0.7	-2.0	-0.0
Frequency of depressed mood in last 2 weeks	0.7	1.0	1.3	1.2	1.0	-0.9
Medication for hormone replacement therapy	0.7	0.8	2.0	-0.3	0.4	1.4
Maternal smoking around birth	0.7	1.0	2.9	0.2	0.4	-1.7
Tinnitus: Yes, but not now, but have in the past	0.7	0.7	1.4	-0.9	-1.2	0.2
Medication: Levothyroxine sodium	0.7	1.3	2.9	-0.8	-1.7	0.4
Body mass index (BMI)	0.7	3.0	5.7	2.4	1.5	1.1
Exposure to tobacco smoke at home	0.7	0.8	2.3	-0.3	0.3	1.5
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.0	1.6	1.3	1.1	-0.5
Exposure to tobacco smoke outside home	0.7	0.9	1.7	0.5	1.3	-0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.7	0.9	1.2	0.6	1.1	-1.1
Migraine (self-reported)	0.7	0.8	1.9	1.4	0.7	-0.3
Pulse rate, automated reading	0.7	2.3	2.9	-1.7	-1.7	-1.0
Average weekly red wine intake	0.7	1.0	1.8	-1.4	-0.9	0.6
Handedness (chirality/laterality): Left-handed	0.7	0.9	1.2	-1.1	-0.9	0.7
Loneliness, isolation	0.7	1.0	1.7	1.1	1.3	0.2
Medication for cholesterol	0.7	1.1	2.5	1.6	0.8	-0.3
Bipolar Disorder (2018)	0.6	0.9	2.0	1.4	-0.5	0.7
Bipolar Disorder or Schizophrenia	0.6	1.6	2.4	1.2	0.9	1.6
Schizophrenia vs Biploar Disorder	0.6	0.8	1.4	0.2	1.2	0.9
Body Mass Index (BMI) (2010)	0.6	0.8	2.4	1.6	0.1	0.3
Crohns Disease (2012)	0.6	1.0	1.7	0.3	-1.0	1.3
BMI	0.6	3.5	7.1	2.7	1.4	1.1
Respiratory disease	0.6	1.4	2.9	-1.7	-1.1	0.4
Relative age of first facial hair	0.6	1.3	2.5	0.5	1.1	1.6
Diabetes (father)	0.6	0.7	2.0	-0.2	-0.2	-1.4
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	1.3	1.1	0.8	0.3
Trunk fat mass	0.6	2.6	5.2	2.3	0.7	1.5
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	1.9	1.4	0.2	-0.9
Illnesses of siblings	0.6	0.8	1.2	1.1	1.0	0.6
Falls in the last year	0.6	0.8	1.5	0.7	0.7	-1.2
Prospective memory result	0.6	0.7	1.1	-0.7	-1.0	-0.7
Illnesses of mother	0.6	0.7	2.0	0.1	-0.4	1.4
Breastfed as a baby	0.6	0.7	1.5	0.4	0.8	1.2
Birth weight of first child	0.6	1.0	2.8	0.1	-1.7	-0.6
Qualifications: O levels/GCSEs or equivalent	0.6	0.9	1.1	-1.0	-1.0	-0.9
Eye problems/disorders: None of the above	0.6	0.7	1.3	-0.4	-1.1	-0.8
Heart disease (mother)	0.6	0.7	0.9	1.0	0.9	-0.4
Whole body fat mass	0.6	2.5	5.3	2.3	0.8	1.2
Leg pain on walking	0.6	0.8	1.3	-1.1	-1.0	0.2
Illness, injury, bereavement, stress in last 2 years	0.6	0.7	1.2	-1.0	-1.1	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.6	1.1	-1.1	-0.1	0.8
Mouth/teeth dental problems: Mouth ulcers	0.6	1.0	2.8	-0.5	-1.7	-0.1
Medication: Blood pressure	0.6	1.1	2.6	-1.6	-0.8	0.4
Medication: Bendroflumethiazide	0.6	0.9	1.3	-1.2	-1.1	0.4
Alcohol drinker status: Never	0.6	0.8	2.1	0.4	0.1	-1.5
Fractured/broken bones in last 5 years	0.6	0.7	2.1	1.5	-0.1	0.1
Ever depressed for a whole week	0.6	0.7	2.0	1.4	0.4	-0.1
HbA1C	0.5	0.6	1.6	-0.1	0.1	-1.3
Smoking Status	0.5	1.2	2.4	0.9	1.6	0.6
Chronotype (morning person)	0.5	1.1	3.1	-0.2	-0.4	-1.8
Heart attack	0.5	0.7	1.4	0.2	1.2	-0.8
Pain all over the body in last month	0.5	0.5	1.3	-0.4	1.1	0.4
Neuroticism score	0.5	1.1	2.4	1.6	1.0	0.1
Father’s age at death	0.5	0.6	0.7	0.9	0.7	-0.8
Serious illness, injury or assault of a close relative in last 2 years	0.5	0.6	1.2	-0.0	0.8	1.1
Medication: Cholesterol lowering	0.5	0.8	1.5	-0.7	-0.7	-1.2
Number of full brothers	0.5	0.6	1.4	-1.2	-0.2	0.5
Medication: Seretide 50 evohaler	0.5	0.6	1.0	-0.9	0.1	1.0
Leg fat mass (right)	0.5	1.8	4.7	2.2	0.8	0.5
Chest pain or discomfort	0.5	0.8	1.5	-0.6	-0.7	1.2
Commuting to job workplace: Car/motor vehicle	0.5	0.5	1.6	-0.0	-0.0	-1.2
Long-standing illness, disability or infirmity	0.5	0.8	1.2	-1.0	-1.1	0.4
Miserableness	0.5	0.9	2.6	1.6	0.1	0.1
Wears glasses or contact lenses	0.5	0.6	1.4	-0.2	-0.7	1.2
High cholesterol (Self-reported)	0.5	1.0	1.4	-1.1	-1.2	-0.6
Ever had prostate specific antigen (PSA) test	0.5	0.6	1.7	0.2	-0.3	-1.3
Myopia	0.5	0.7	1.4	0.4	-1.2	-0.8
Heart attack/myocardial infarction (self-reported)	0.5	0.6	1.4	0.3	1.2	-0.6
Leg fat mass (left)	0.5	2.0	4.9	2.2	0.9	0.5
Intelligence (Savage-Jansen 2018)	0.4	1.2	1.5	-1.2	-1.2	-0.8
Neuroticism (2016)	0.4	0.6	1.4	0.4	-0.3	-1.2
Rheumatoid Arthritis	0.4	0.6	1.8	-0.1	-0.0	-1.4
Cardiovascular Disease	0.4	1.3	2.1	-1.2	-1.4	-0.7
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	1.1	-0.3	1.0	-0.5
Severe depression (siblings)	0.4	0.4	1.0	-0.5	-0.3	-1.0
Hand grip strength (right)	0.4	1.0	2.4	-0.6	-1.6	-0.4
Taking other prescription medications	0.4	0.6	0.7	-0.9	-0.8	-0.6
Age when periods started (menarche)	0.4	0.9	2.7	-0.1	1.6	0.1
High blood pressure	0.4	1.1	2.1	-0.7	-1.5	-0.8
Mouth/teeth dental problems	0.4	0.6	0.8	-0.7	-0.8	-0.9
Mouth/teeth dental problems: Dentures	0.4	0.6	1.7	0.2	1.3	-0.2
High blood pressure (siblings)	0.4	0.6	1.0	-0.4	-0.7	-1.0
Medication: Omeprazole	0.4	0.5	1.3	0.1	-1.2	0.2
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.4	1.0	-0.3	-0.4	1.0
Ever had bowel cancer screening	0.4	0.5	1.2	-0.0	-0.6	1.1
Medication: Aspirin	0.4	0.5	1.2	-0.5	-0.1	-1.1
Smoking status: Current	0.4	0.7	1.7	-0.4	-0.5	1.3
Diastolic blood pressure, automated reading	0.4	1.4	2.2	1.5	1.2	0.6
Vascular/heart problems diagnosed by doctor	0.4	1.1	1.8	0.7	1.3	1.0
Ovarian Cancer	0.3	0.5	0.6	-0.8	-0.6	-0.7
Neuroticism	0.3	0.7	1.2	0.9	1.1	0.5
Tanning	0.3	4.1	9.3	0.8	1.6	3.0
Systolic blood pressure, automated reading	0.3	0.8	1.6	-0.7	-0.6	-1.3
Medication: Co-codamol	0.3	0.4	0.5	-0.7	-0.5	-0.5
Current tobacco smoking	0.3	0.5	1.3	-0.2	-0.3	1.1
Diverticular disease/diverticulitis (self-reported)	0.3	0.3	0.6	0.8	0.6	0.1
Hearing difficulty/problems with background noise	0.3	0.5	1.0	-0.7	0.3	-1.0
Forced vital capacity (FVC)	0.3	1.1	1.6	1.3	1.2	0.2
Fluid intelligence score	0.3	0.6	1.3	-0.6	-0.5	-1.1
Ever highly irritable/argumentative for 2 days	0.3	0.4	1.1	0.1	-1.0	0.2
Medication for cholesterol, blood pressure or diabetes	0.3	0.5	0.8	0.4	0.8	0.9
Seen a psychiatrist for nerves, anxiety, tension or depression	0.3	0.3	0.5	0.7	0.5	0.5
Wheeze or whistling in the chest in last year	0.3	0.5	1.2	-0.2	-0.5	1.1
Shortness of breath walking on level ground	0.3	0.4	0.9	-0.2	0.5	1.0
Overall health rating	0.3	0.7	1.6	1.3	0.1	-0.5
Hypertension (Self-reported)	0.3	0.9	1.4	-0.7	-1.2	-1.0
Illnesses of father: Heart disease	0.3	0.4	1.3	0.1	-0.0	-1.1
Breast cancer (self-reported)	0.3	0.3	0.5	-0.6	0.3	0.7
Average weekly champagne plus white wine intake	0.3	0.3	0.6	0.8	0.4	-0.5
Pain type(s) experienced in last month: Hip pain	0.3	0.4	1.0	1.0	-0.0	-0.4
Age started oral contraceptive pill	0.3	0.4	0.9	-0.6	-0.0	-1.0
Verbal and Numeric Reasoning (VNR)	0.2	0.4	0.5	0.6	0.6	0.7
Age at First Birth	0.2	0.3	0.9	0.9	0.2	0.0
HDL Cholesterol	0.2	0.4	0.7	-0.2	-0.6	0.8
Lupus	0.2	0.3	0.4	0.5	-0.4	-0.6
Primary Biliary Cirrhosis	0.2	0.3	0.5	-0.5	0.0	-0.7
Hair Pigment	0.2	5.1	10.3	1.7	3.2	1.5
Average weekly spirits intake	0.2	0.2	0.5	0.1	0.5	0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.2	0.5	1.0	-0.6	-0.1	-1.0
Financial difficulties in last 2 years	0.2	0.3	0.4	0.6	-0.1	-0.7
Medication: Ramipril	0.2	0.3	0.8	0.2	0.1	0.9
Forced expiratory volume in 1-second (FEV1)	0.2	0.6	1.1	1.0	0.9	-0.1
Depression (self-reported)	0.2	0.2	0.4	0.6	0.3	-0.2
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.5	0.7	0.8	0.9	0.3
Mouth/teeth dental problems: Bleeding gums	0.2	0.3	0.6	0.8	-0.3	0.4
Gout (self-reported)	0.2	0.3	0.7	0.6	-0.0	0.8
Medication: Amlodipine	0.2	0.3	0.7	0.8	0.5	0.1
Medication: Ventolin 100micrograms inhaler	0.2	0.3	0.8	-0.9	-0.2	-0.3
Chronic bronchitis/emphysema (mother)	0.2	0.3	0.3	-0.5	-0.4	0.6
Forced vital capacity (FVC), Best measure	0.2	0.6	0.8	0.8	0.9	0.5
Health satisfaction	0.2	0.3	0.6	0.8	0.3	0.3
Neck or shoulder pain in last month	0.2	0.3	0.4	0.5	-0.7	-0.2
Medication: Blood pressure	0.2	0.4	0.6	-0.4	-0.7	-0.8
Medication: Allopurinol	0.2	0.3	0.5	0.4	-0.7	-0.5
Mean time to correctly identify matches	0.2	0.3	0.5	-0.7	-0.4	0.4
Alcohol intake frequency.	0.2	0.4	0.8	0.9	-0.1	0.6
Suffer from ‘nerves’	0.2	0.4	1.0	0.2	0.2	-1.0
Medication: Aspirin	0.2	0.3	0.6	-0.3	-0.3	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.2	0.3	0.6	-0.3	-0.8	0.1
Illnesses of siblings: Diabetes	0.2	0.3	0.6	0.1	-0.8	-0.4
Illnesses of father: None of the above (group 1)	0.2	0.2	0.5	-0.2	0.3	0.7
Financial situation satisfaction	0.2	0.2	0.5	0.7	0.4	-0.1
Medication: Lisinopril	0.2	0.2	0.3	-0.4	-0.5	-0.6
Number of operations (self-reported)	0.2	0.3	0.9	0.9	-0.1	-0.1
Irritability	0.2	0.3	0.6	0.8	0.4	-0.4
Supplements: Calcium	0.2	0.3	0.4	0.5	0.7	0.3
Alcohol drinker status: Previous	0.2	0.2	0.5	0.1	-0.1	0.7
Prostate Cancer	0.1	0.1	0.3	-0.0	0.3	0.6
LDL Cholesterol	0.1	0.2	0.5	0.3	0.7	0.3
Blood White Count	0.1	0.9	1.8	-1.4	0.4	-0.9
Lung FEV1/FVC ratio	0.1	0.5	1.3	-0.4	-0.1	-1.2
Number of treatments/medications taken	0.1	0.1	0.2	-0.1	-0.4	0.5
Sensitivity / hurt feelings	0.1	0.1	0.3	0.0	-0.3	-0.5
Average weekly fortified wine intake	0.1	0.1	0.2	0.4	0.2	-0.4
Serious illness, injury or assault to yourself	0.1	0.1	0.2	-0.2	0.0	-0.4
Waist circumference	0.1	0.4	1.0	1.0	-0.3	-0.3
Number of incorrect matches in round	0.1	0.2	0.4	0.5	-0.3	-0.6
Had menopause	0.1	0.1	0.2	-0.1	0.5	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	0.1	0.3	0.7	0.1	0.8	-0.3
Arm fat percentage (right)	0.1	0.5	1.1	1.1	0.5	-0.2
Worrier / anxious feelings	0.1	0.2	0.3	0.6	-0.5	0.0
Noisy workplace	0.1	0.1	0.2	0.0	0.4	-0.2
Qualifications: A levels/AS levels or equivalent	0.1	0.2	0.3	-0.5	-0.2	0.5
Lung cancer (father)	0.1	0.2	0.4	0.1	-0.6	-0.2
Tense / ‘highly strung’	0.1	0.2	0.3	0.6	0.4	-0.4
Pulse wave reflection index	0.1	0.1	0.2	0.3	0.1	-0.4
Body fat percentage	0.1	0.3	0.6	0.4	-0.2	-0.8
Leg fat percentage (right)	0.1	0.4	1.2	0.2	-0.1	-1.1
Comparative body size at age 10	0.1	0.2	0.6	0.8	-0.1	-0.0
Pulse wave peak to peak time	0.1	0.1	0.3	0.2	0.1	0.5
Number of full sisters	0.1	0.2	0.4	0.0	-0.3	0.6
Supplements: Vitamin C	0.1	0.1	0.2	0.2	0.0	-0.5
Arm fat percentage (left)	0.1	0.5	1.2	1.1	0.6	0.2
Eye problems/disorders: Cataract	0.1	0.2	0.4	-0.7	-0.2	-0.2
Guilty feelings	0.1	0.1	0.2	0.0	-0.4	-0.5
Leg fat percentage (left)	0.1	0.5	1.3	0.4	0.1	-1.1
Risk taking	0.1	0.1	0.2	0.4	0.5	-0.0
Unable to work because of sickness or disability	0.1	0.1	0.2	0.2	0.4	-0.1
Medication: Omeprazole (e.g. Zanprol)	0.1	0.2	0.5	0.1	-0.7	-0.0
Major Depression (MDD)	0.0	0.0	0.1	0.3	0.0	0.2
Blood Platelet Count	0.0	0.3	0.7	-0.8	0.0	-0.3
Blood Red Count	0.0	0.5	1.3	-1.1	-0.3	0.3
Trunk fat percentage	0.0	0.1	0.2	0.3	-0.4	-0.3
Stomach or abdominal pain in last month	0.0	0.1	0.1	0.0	-0.4	0.2
Pulse wave Arterial Stiffness index	0.0	0.0	0.1	0.3	0.2	0.1
Birth weight	0.0	0.1	0.2	0.0	0.4	0.2
Osteoporosis (self-reported)	0.0	0.0	0.0	-0.1	-0.1	0.1

Hub : Genes

FGF2

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Trait associations